Induction of G1 arrest and apoptosis by schisandrin C isolated from Schizandra chinensis Baill in human leukemia U937 cells

International Journal of Molecular Medicine

Volumn 24, Issue 4, 2009, Pages 495-502

  Park, Cheol ^a   Choi, Young Whan ^b   Hyun, Sook Kyung ^a   Kwon, Hyun Ju ^a   Hwang, Hye Jin ^a   Kim, Gi Young ^c   Choi, Byung Tae ^a,b   Kim, Byung Woo ^a   Choi, Il Whan ^d   Moon, Sung Kwon ^e   Kim, Wun Jae ^f   Choi, Yung Hyun ^a  

^a Dong Eui University   (South Korea)

^b Pusan National University   (South Korea)

^c Jeju National University   (South Korea)

^d Inje University College of Medicine   (South Korea)

^e Chungju National University   (South Korea)

^f Chungbuk National University College of Medicine   (South Korea)

Author keywords

Apoptosis; G1 arrest; Schisandrin C; U937

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN E; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; RETINOBLASTOMA PROTEIN; SCHIZANDRIN; SCHIZANDRIN C; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL STRAIN U937; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SCHISANDRACEAE; STRUCTURE ACTIVITY RELATION; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CYCLOOCTANES; DNA FRAGMENTATION; G1 PHASE; HUMANS; LEUKEMIA; LIGNANS; MOLECULAR STRUCTURE; POLYCYCLIC COMPOUNDS; SCHISANDRA; U937 CELLS;

EID: 70350763608     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000258     Document Type: Article

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