Quantitative interference by cysteine and N-acetylcysteine metabolites during the LC-MS/MS bioanalysis of a small molecule

Drug Metabolism Letters

Volumn 3, Issue 3, 2009, Pages 181-190

  Barricklow, Jason ^a   Ryder, Tim F ^a   Furlong, Michael T ^a  

^a PFIZER INC   (United States)

Author keywords

Chromatography; Co elution; Cysteine; Interference; Metabolite; Quantification

Indexed keywords

ACETYLCYSTEINE; CYSTEINE; GLUTATHIONE; THIOL;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; HUMAN; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MOLECULAR STABILITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY;

ACETYLCYSTEINE; ARTIFACTS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; CYSTEINE; HUMANS; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; URINALYSIS;

EID: 70350716451     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231209789352148     Document Type: Article

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