Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct

Biochemistry

Volumn 48, Issue 30, 2009, Pages 7079-7088

  Eoff, Robert L ^a   Stafford, Jennifer B ^a   Szekely, Jozsef ^a   Rizzo, Carmelo J ^a   Egli, Martin ^a   Guengerich, F Peter ^a   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; DNA POLYMERASE; DUPLEX DNA; ELECTROPHILES; FRAMESHIFT; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MALONDIALDEHYDE; MAMMALIAN CELLS; MINOR GROOVES; MUTAGENICITY; PEROXIDATION; PHYSIOLOGICAL PH; PROPENALS; RING OPENING; SOS RESPONSE; STRUCTURAL STUDIES; SULFOLOBUS SOLFATARICUS; TRANSLESION; TYPE II;

ALDEHYDES; ESCHERICHIA COLI; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PH; POLYMERS;

DNA;

ARCHAEAL PROTEIN; DEOXYGUANOSINE; DNA; DNA DIRECTED DNA POLYMERASE; MALONALDEHYDE;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA ADDUCT; DNA REPLICATION; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; MACROMOLECULE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; SULFOLOBUS SOLFATARICUS; X RAY CRYSTALLOGRAPHY;

ANIMALS; ARCHAEAL PROTEINS; BASE SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DEOXYGUANOSINE; DNA; DNA ADDUCTS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; MACROMOLECULAR SUBSTANCES; MALONDIALDEHYDE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; SULFOLOBUS SOLFATARICUS;

EID: 70350714934     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi9003588     Document Type: Article

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