Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo

Biomaterials

Volumn 31, Issue 2, 2010, Pages 339-344

  Tang, Benjamin C ^a   Fu, Jie ^a   Watkins, D Neil ^c   Hanes, Justin ^a,b  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c MONASH MEDICAL CENTRE   (Australia)

Author keywords

Biodegradable polymers; Cancer; Controlled release; Drug delivery; Mucus penetrating particles

Indexed keywords

AEROSOLIZATION; CANCER; CONTROLLED RELEASE; CYTOTOXIC ACTIVITIES; DRUG CARRIER; ETOPOSIDE; HUMAN LUNG TUMORS; HUMAN MUCUS; IN-VITRO; IN-VIVO; INTRAPERITONEAL ADMINISTRATION; LOCAL THERAPY; MOUSE MODELS; MUCUS-PENETRATING PARTICLES; ONE-STEP PROCESS; SEBACIC ACID; SMALL CELL LUNG CANCERS;

ANIMALS; BIODEGRADABLE POLYMERS; BIOLOGICAL ORGANS; BODY FLUIDS; CELL CULTURE; CYTOTOXICITY; DRUG THERAPY; ETHERS; ETHYLENE; ETHYLENE GLYCOL; PEELING; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; TUMORS;

CONTROLLED DRUG DELIVERY;

DRUG CARRIER; ETOPOSIDE; MACROGOL CO POLY(SEBACIC ACID); PLACEBO; POLY(ETHER ANHYDRIDE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG RELEASE; ENCAPSULATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; CELL LINE, TUMOR; DECANOIC ACIDS; DICARBOXYLIC ACIDS; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; ETOPOSIDE; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; KINETICS; LUNG NEOPLASMS; MICE; MICROSCOPY, ELECTRON, SCANNING; POLYETHYLENE GLYCOLS; SMALL CELL LUNG CARCINOMA; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA;

EID: 70350709937     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.09.033     Document Type: Article

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