Adapting the logical basis of tests for Hardy-Weinberg equilibrium to the real needs of association studies in human and medical genetics

Genetic Epidemiology

Volumn 33, Issue 7, 2009, Pages 569-580

  Goddard, Katrina A B ^a,b,e   Ziegler, Andreas ^c   Wellek, Stefan ^d  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^c UNIVERSITY OF LÜBECK   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e CENTER FOR HEALTH RESEARCH   (United States)

Author keywords

Equivalence test; Genome wide association study; Genotyping error; Goodness of fit test; One sided test; Population stratification

Indexed keywords

ARTICLE; CALCULATION; CONTROLLED STUDY; GENETIC ASSOCIATION; GENOTYPE; HARDY WEINBERG DISTRIBUTION LAW; HUMAN; HUMAN GENETICS; MEDICAL GENETICS; NULL HYPOTHESIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VARIANCE;

ALLELES; DATA INTERPRETATION, STATISTICAL; GENE FREQUENCY; GENETICS, POPULATION; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MODELS, GENETIC; MODELS, STATISTICAL; MODELS, THEORETICAL; REPRODUCIBILITY OF RESULTS; STATISTICS AS TOPIC;

EID: 70350686160     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20409     Document Type: Article

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