Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: A hospital-based case-control study in Japan

Scandinavian Journal of Gastroenterology

Volumn 44, Issue 8, 2009, Pages 952-959

  Kobayashi, Minatsu ^a,b   Otani, Tetsuya ^a   Iwasaki, Motoki ^a   Natsukawa, Shusuke ^c   Shaura, Kozo ^d   Koizumi, Yoichi ^e   Kasuga, Yoshio ^f   Sakamoto, Hiromi ^g   Yoshida, Teruhiko ^g   Tsugane, Shoichiro ^a  

^a NATIONAL CANCER CENTER   (Japan)

^b OTSUMA WOMEN'S UNIVERSITY   (Japan)

^c Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare   (Japan)

^d Hokushin General Hospital   (Japan)

^e Shinonoi General Hospital   (Japan)

^f Nagano Matsushiro General Hospital   (Japan)

^g NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Colorectal cancer; CYP1A1; CYP1A2; HCA; NAT2

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; HETEROCYCLIC AMINE;

ADULT; AGED; ALLELE; ARTICLE; CANCER RISK; COLORECTAL CANCER; CONTROLLED STUDY; DIET; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HAIR; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; QUESTIONNAIRE; SAMPLE SIZE;

ADULT; AGED; ARYLAMINE N-ACETYLTRANSFERASE; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; FEMALE; HETEROCYCLIC COMPOUNDS; HUMANS; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 70350657309     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520902964721     Document Type: Article

References (34)

1. Augustsson K, Skog K, Jagerstad M, Dickman PW, Steineck G. Dietary heterocyclic amines and cancer of the colon, rectum, bladder, and kidney: a population-based study. Lancet 1999;/353:/703-7.
2. Butler LM, Sinha R, Millikan RC, Martin CF, Newman B, Gammon MD, et al. Heterocyclic amines, meat intake, and association with colon cancer in a population-based study. Am J Epidemiol 2003;/157:/434-45.
3. Nowell S, Coles B, Sinha R, MacLeod S, Luke Ratnasinghe D, Stotts C, et al. Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk. Mutat Res 2002;/506-507:/175-85.
4. Sinha R, Kulldorff M, Chow WH, Denobile J, Rothman N. Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomas. Cancer Epidemiol Biomarkers Prev 2001;/10:/559-62.
5. Wu K, Giovannucci E, Byrne C, Platz EA, Fuchs C, Willett WC, et al. Meat mutagens and risk of distal colon adenoma in a cohort of U.S. men. Cancer Epidemiol Biomarkers Prev 2006;/15:/1120-5.
6. Kobayashi M, Hanaoka T, Tsugane S. Validity of a selfadministered food frequency questionnaire in the assessment of heterocyclic amine intake using 2-amino-1-methyl-6- phenylimidazo [4,5-b] pyridine (PhIP) levels in hair. Mutat Res 2007;/630:/14-9.
7. Kobayashi M, Hanaoka T, Nishioka S, Kataoka H, Tsugane S. Estimation of dietary HCA intakes in a large-scale population-based prospective study in Japan. Mutat Res 2002;/506-507:/233-41.
8. McManus ME, Burgess WM, Veronese ME, Huggett A, Quattrochi LC, Tukey RH. Metabolism of 2-acetylamino- fluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450. Cancer Res 1990;/50:/3367-76.
9. Brockton N, Little J, Sharp L, Cotton SC. N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review. Am J Epidemiol 2000;/151:/846-61. (Pubitemid 30461126)
10. Barrett JH, Smith G, Waxman R, Gooderham N, Lightfoot T, Garner RC, et al. Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer. Carcinogenesis 2003;/24:/ 275-82.
11. Goode EL, Potter JD, Bamlet WR, Rider DN, Bigler J. Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps. Carcinogenesis 2007;/28:/328-41.
12. Le Marchand L, Hankin JH, Wilkens LR, Pierce LM, Franke A, Kolonel LN, et al. Combined effects of welldone red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2001;/10:/1259-66.
13. Murtaugh MA, Sweeney C, Ma KN, Caan BJ, Slattery ML. The CYP1A1 genotype may alter the association of meat consumption patterns and preparation with the risk of colorectal cancer in men and women. J Nutr 2005;/135:/ 179-86.
14. Sasaki S, Kobayashi M, Ishihara J, Tsugane S. Selfadministered food frequency questionnaire used in the 5-year follow-up survey of the JPHC Study: questionnaire structure, computation algorithms, and area-based mean intake: Japan Epidemiological Association. J Epidemiol 2003;/13 Suppl 1:/S13-22.
15. Ross P, Hall L, Smirnov I, Haff L. High level multiplex genotyping by MALDI-TOF mass spectrometry. Nat Biotechnol 1998;/16:/1347-51.
16. Yoshimura K, Hanaoka T, Ohnami S, Ohnami S, Kohno T, Liu Y, et al. Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples. J Hum Genet 2003;/48:/654-8.
17. WillettW, Stampfer MJ. Total energy intake: implications for epidemiologic analyses. Am J Epidemiol 1986;/124:/17-27.
18. Shin A, Shrubsole MJ, Ness RM, Wu H, Sinha R, Smalley WE, et al. Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: the Tennessee Colorectal Polyp Study. Int J Cancer 2007;/121:/136-42.
19. GunterMJ, Probst-Hensch NM, Cortessis VK, Kulldorff M, Haile RW, Sinha R. Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study. Carcinogenesis 2005;/26:/637-42.
20. Mucci LA, Wedren S, Tamimi RM, Trichopoulos D, Adami HO. The role of gene-environment interaction in the aetiology of human cancer: examples from cancers of the large bowel, lung and breast. J Intern Med 2001;/249:/ 477-93.
21. Hein DW. Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis. Mutat Res 2002;/506-507:/65-77.
22. Roberts-Thomson IC, Ryan P, Khoo KK, Hart WJ, McMichael AJ, Butler RN. Diet, acetylator phenotype, and risk of colorectal neoplasia. Lancet 1996;/347:/1372-4.
23. Hein DW, Doll MA, Fretland AJ, Leff MA, Webb SJ, Xiao GH, et al. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol Biomarkers Prev 2000;/9:/29-42.
24. Agundez JAG, Lozano L, Ladero JM, Sastre J, Cerdan FJ, Diaz-Rubio M, et al. N-acetyltransferase 2 (NAT2) genotype and colorectal carcinoma: risk variability according to tumour site? Scand J Gastroenterol 2000;/35:/1087-91.
25. Chan AT, Tranah GJ, Giovannucci EL, Willett WC, Hunter DJ, Fuchs CS. Prospective study of N-acetyltransferase-2 genotypes, meat intake, smoking and risk of colorectal cancer. Int J Cancer 2005;/115:/648-52.
26. Sorensen M, Autrup H, Olsen A, Tjonneland A, Overvad K, Raaschou-Nielsen O. Prospective study of NAT1 and NAT2 polymorphisms, tobacco smoking and meat consumption and risk of colorectal cancer. Cancer Lett 2008;/266:/186-93.
27. van der Hel OL, Bueno de Mesquita HB, Sandkuijl L, van Noord PA, Pearson PL, Grobbee DE, et al. Rapid N-acetyltransferase 2 imputed phenotype and smoking may increase risk of colorectal cancer in women (Netherlands). Cancer Causes Control 2003;/14:/293-8.
28. Le Marchand L, Hankin JH, Pierce LM, Sinha R, Nerurkar PV, Franke AA, et al. Well-done red meat, metabolic phenotypes and colorectal cancer in Hawaii. Mutat Res 2002;/506-7:/205-14. (Pubitemid 35286555)
29. Tiemersma EW, Voskuil DW, Bunschoten A, Hogendoorn EA, Witteman BJ, Nagengast FM, et al. Risk of colorectal adenomas in relation to meat consumption, meat preparation, and genetic susceptibility in a Dutch population. Cancer Causes Control 2004;/15:/225-36.
30. Ishibe N, Sinha R, Hein DW, Kulldorff M, Strickland P, Fretland AJ, et al. Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas. Pharmacogenetics 2002;/12:/145-50.
31. Kato R. Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates. Crit Rev Toxicol 1986;/16:/307-48.
32. Shimada T, Guengerich FP. Activation of amino-alphacarboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes. Cancer Res 1991;/51:/ 5284-91.
33. Sachse C, Smith G, Wilkie MJ, Barrett JH, Waxman R, Sullivan F, et al. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. Carcinogenesis 2002;/23:/1839-49.
34. Bae SY, Choi SK, Kim KR, Park CS, Lee SK, Roh HK, et al. Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans. Cancer Sci 2006;/97:/774-9.