Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells

Toxicology and Applied Pharmacology

Volumn 241, Issue 3, 2009, Pages 275-282

  Suzuki, Toshihide ^a   Miyazaki, Koichi ^a   Kita, Kayoko ^a   Ochi, Takafumi ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Arsenite; Aurora B kinase; Cytokinesis; Dimethylarsinous acid DMA(III) ; Histone H3; Multipolar spindles; Phosphorylation

Indexed keywords

ARSENIC DERIVATIVE; AURORA B KINASE; DIMETHYLARSINOUS ACID DERIVATIVE; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CELLULAR DISTRIBUTION; CENTROSOME; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; CYTOKINESIS; CYTOTOXICITY; HUMAN; HUMAN CELL; MITOSIS; MITOSIS SPINDLE; MULTINUCLEAR CELL; PROMETAPHASE; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TELOPHASE;

ARSENITES; BENZAMIDES; BLOTTING, WESTERN; CACODYLIC ACID; CELL LINE; CELL SURVIVAL; CENTROSOME; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HISTONES; HUMANS; LIVER; MITOTIC INDEX; MITOTIC SPINDLE APPARATUS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; QUINAZOLINES;

EID: 70350599526     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.08.017     Document Type: Article

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