Cytotoxic, genotoxic and cell-cycle disruptive effects of thio-dimethylarsinate in cultured human cells and the role of glutathione

Toxicology and Applied Pharmacology

Volumn 228, Issue 1, 2008, Pages 59-67

  Ochi, Takafumi ^a   Kita, Kayoko ^a   Suzuki, Toshihide ^a   Rumpler, Alice ^b   Goessler, Walter ^b   Francesconi, Kevin A ^b  

^a TEIKYO UNIVERSITY   (Japan)

^b UNIVERSITY OF GRAZ   (Austria)

Author keywords

Apoptosis; Cytotoxicity; Genotoxicity; Glutathione; Spindle abnormality; Thio dimethylarsinate (thio DMA)

Indexed keywords

CACODYLIC ACID; GLUTATHIONE; THIO DIMETHYLARSINATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL DISRUPTION; CELL STRAIN HEPG2; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; GENOTOXICITY; HUMAN; HUMAN CELL;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CACODYLIC ACID; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CENTROSOME; CHROMATIDS; CHROMOSOME ABERRATIONS; CHROMOSOMES; CRICETINAE; DNA FRAGMENTATION; FLOW CYTOMETRY; GLUTATHIONE; HUMANS; MITOTIC SPINDLE APPARATUS; MUTAGENS;

MESOCRICETUS AURATUS;

EID: 40849085135     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.11.023     Document Type: Article

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