Genotype of the CYBA promoter -930A/G, polymorphism C677T of the MTHFR and APOE genotype in patients with hypertensive disorders of pregnancy: An observational study

Medicina Clinica

Volumn 133, Issue 17, 2009, Pages 657-661

  Stiefel, Pablo ^a   Miranda, María Luisa ^a   Bellido, Lola M ^b   Luna, Jerónimo ^b   Jiménez, Luis ^a   Pamies, Encarnación ^a   De Frutos, Pablo García ^b   Villar, José ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Apolipoprotein E; CYBA; Gestational hypertension; MTHFR; P22phox; Polymorphism; Preeclampsia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALANINE; APOLIPOPROTEIN E; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; CHOLESTEROL; CYSTEINE; CYTOCHROME B; CYTOCHROME B245; GLYCINE; HOMOCYSTEINE; LIPOPROTEIN; THREONINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE COURSE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; HYPERTENSION; LABORATORY TEST; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; NONPROTEINURIC HYPERTENSION; OBSERVATIONAL STUDY; PREECLAMPSIA; PREGNANCY; PROMOTER REGION; PROTEIN LOCALIZATION; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; APOLIPOPROTEINS E; FEMALE; GENOTYPE; HUMANS; HYPERTENSION; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); NADPH OXIDASE; POLYMORPHISM, GENETIC; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR;

EID: 70350572246     PISSN: 00257753     EISSN: 15788989     Source Type: Journal    
DOI: 10.1016/j.medcli.2009.03.042     Document Type: Article

References (30)

1. C. Calvo, R.C. Hermida, D.E. Ayala, J.E. López, J.R. Fernández, A. Mojón, et al. Effects of time-dependent administration of antihypertensive treatment in patients with resistant hypertension Med Clin (Barc) 126 2006 364 372
2. C. Sierra, A. De la Sierra, J. Sobrino, J. Segura, J.R. Banegas, M. Gorostidi, et al. en representación de los Investigadores del Registro Nacional de MAPA. Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA). Ambulatory blood pressure monitoring (CABPM): clinical characteristics of 31,530 patients Med Clin (Barc) 129 2007 1 5
3. E. Rodilla, J.A. Costa, F. Pérez-Lahiguera, C. González, and J.M. Pascual Spironolactone in patients with resistant hypertension Med Clin (Barc) 131 2008 406 411
4. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy Am J Obstet Gynecol 183 2000 S1 S22
5. F. Broughton-Pipkin What is the place of genetics in the pathogenesis of pre-eclampsia? Biol Neonate 76 1999 325 330
6. A. Hata Role of angiotensinogen in the genetics of essential hypertension Life Sci 57 1995 2385 2395
7. L. Morgan, F. Foster, R. Hayman, S. Crawshaw, P.N. Baker, P.F. Broughton, et al. Angiotensin-converting enzyme insertion-deletion polymorphism in normotensive and pre-eclamptic pregnancies J Hypertens 17 1999 765 768
8. J.C. Cross The genetics of pre-eclampsia: a feto-placental or maternal problem? Clin Genet 64 2003 96 103
9. S. Chappell, and L. Morgan Searching for genetic clues to the causes of pre-eclampsia Clin Sci (Lond) 110 2006 443 458
10. K. Tsukimori, K. Fukushima, A. Tsushima, and H. Nakano Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnancies Hypertension 46 2005 696 700
11. I. Craici, S. Wagner, and V.D. Garovic Preeclampsia and future cardiovascular risk: formal risk factor or failed stress test? Ther Adv Cardiovasc Dis 2 2008 249 259
12. O.S. Descamps, M. Bruniaux, P.F. Guilmot, R. Tonglet, and F.R. Heller Lipoprotein metabolism of pregnant women is associated with both their genetic polymorphisms and those of their newborn children J Lipid Res 46 2005 2405 2414
13. P.M. Ueland, H. Refsum, S.P. Stabler, M.R. Malinow, A. Andersson, and R.H. Allen Total homocysteine in plasma or serum: methods and clinical applications Clin Chem 39 1993 1764 1779
14. M.U. Moreno, G. San Jose, J. Orbe, J.A. Paramo, O. Beloqui, J. Diez, et al. Preliminary characterisation of the promoter of the human p22(phox) gene: identification of a new polymorphism associated with hypertension FEBS Lett 542 2003 27 31
15. P.R. Wenham, W.H. Price, and G. Blandell Apolipoprotein E genotyping by one-stage PCR Lancet 337 1991 1158 1159
16. P. Frosst, H.J. Blom, R. Milos, P. Goyette, C.A. Sheppard, R.G. Matthews, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Nat Genet 10 1995 111 113
17. G. Zalba, G. San Jose, F.J. Beaumont, M.A. Fortuno, A. Fortuno, and J. Diez Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats Circ Res 88 2001 217 222
18. G. San Jose, M.U. Moreno, S. Olivan, O. Beloqui, A. Fortuno, J. Diez, et al. Functional effect of the p22phox -930A/G polymorphism on p22phox expression and NADPH oxidase activity in hypertension Hypertension 44 2004 163 169
19. Y. Kokubo, N. Iwai, N. Tago, N. Inamoto, A. Okayama, and H. Yamawaki Association analysis between hypertension and CYBA, CLCNKB, and KCNMB1 functional polymorphisms in the Japanese population--the Suita Study Circ J 69 2005 138 142 (Pubitemid 40313030)
20. A. Agarwal, S. Gupta, and R. Sharma Role of oxidative stress in female reproduction Reprod Biol Endocrinol 3 2005 28
21. Y. Song, M.J. Stampfer, and S. Liu Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease Ann Intern Med 141 2004 137 147 (Pubitemid 38937836)
22. C. Sudlow, N.A. Martinez Gonzalez, J. Kim, and C. Clark Does apolipoprotein E genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic review and meta-analyses of 31 studies among 5961 cases and 17,965 controls Stroke 37 2006 364 370
23. K.A. Volcik, R.A. Barkley, R.G. Hutchinson, T.H. Mosley, G. Heiss, A.R. Sharrett, et al. Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants Am J Epidemiol 164 2006 342 348
24. P. Stiefel, C. Montilla, O. Muniz-Grijalvo, R. Garcia-Lozano, A. Alonso, M.L. Miranda, et al. Apolipoprotein E gene polymorphism is related to metabolic abnormalities, but does not influence erythrocyte membrane lipid composition or sodium-lithium countertransport activity in essential hypertension Metabolism 50 2001 157 160
25. J. Francoual, F. Audibert, P. Trioche, J. Chalas, L. Capel, A. Lindenbaum, et al. Is a polymorphism of the apolipoprotein E gene associated with preeclampsia? Hypertens Pregnancy 21 2002 127 133
26. A.B. Chikosi, J. Moodley, R.J. Pegoraro, P.A. Lanning, and L. Rom Apolipoprotein E polymorphism in South African Zulu women with preeclampsia Hypertens Pregnancy 19 2000 309 314 (Pubitemid 30952239)
27. J.M. Roberts, and H.S. Gammill Preeclampsia: recent insights Hypertension 46 2005 1243 1249
28. H. Yilmaz, Y. Unlucerci, F. Gurdol, E. Isbilen, and T. Isbir Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population Aust N Z J Obstet Gynaecol 44 2004 423 427
29. D. Girelli, S. Friso, E. Trabetti, O. Olivieri, C. Russo, R. Pessotto, et al. Methylenetetrahydrofolate reductase C677T mutation, plasma homocysteine, and folate in subjects from northern Italy with or without angiographically documented severe coronary atherosclerotic disease: evidence for an important genetic-environmental interaction Blood 91 1998 4158 4163
30. P. Stiefel, S. Arguelles, S. Garcia, L. Jimenez, R. Aparicio, J. Carneado, et al. Effects of short-term supplementation with folic acid on different oxidative stress parameters in patients with hypertension Biochim Biophys Acta 1726 2005 152 159