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Volumn 164, Issue 4, 2006, Pages 342-348

Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants

Author keywords

Apolipoproteins E; Carotid arteries; Coronary disease; Lipoproteins, LDL cholesterol; Polymorphism, genetic

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 33748074100     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwj202     Document Type: Article
Times cited : (114)

References (40)
  • 1
    • 4243696675 scopus 로고
    • Update on the pathogenesis of atherosclerosis
    • Wissler RW. Update on the pathogenesis of atherosclerosis. Am J Med 1991;91:3S-9S.
    • (1991) Am J Med , vol.91
    • Wissler, R.W.1
  • 3
    • 0032966835 scopus 로고    scopus 로고
    • Relationships of cerebral MRI findings to ultrasonographic carotid atherosclerosis in older adults: The Cardiovascular Health Study
    • CHS Collaborative Research Group
    • Manolio TA, Burke GL, O'Leary DH, et al. Relationships of cerebral MRI findings to ultrasonographic carotid atherosclerosis in older adults: the Cardiovascular Health Study. CHS Collaborative Research Group. Arterioscler Thromb Vasc Biol 1999;19:356-65.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 356-365
    • Manolio, T.A.1    Burke, G.L.2    O'Leary, D.H.3
  • 4
    • 0025681539 scopus 로고
    • Relation of risk factors for cardiovascular disease to early atherosclerosis detected by ultrasonography in middle-aged normotensive hypercholesterolemic men
    • Giral P, Filitti V, Levenson J, et al. Relation of risk factors for cardiovascular disease to early atherosclerosis detected by ultrasonography in middle-aged normotensive hypercholesterolemic men. Atherosclerosis 1990;85:151-9.
    • (1990) Atherosclerosis , vol.85 , pp. 151-159
    • Giral, P.1    Filitti, V.2    Levenson, J.3
  • 5
    • 0026056004 scopus 로고
    • Carotid atherosclerosis measured by B-mode ultrasound in populations: Associations with cardiovascular risk factors in the ARIC Study
    • Heiss G, Sharrett AR, Barnes R, et al. Carotid atherosclerosis measured by B-mode ultrasound in populations: associations with cardiovascular risk factors in the ARIC Study. Am J Epidemiol 1991;134:250-6.
    • (1991) Am J Epidemiol , vol.134 , pp. 250-256
    • Heiss, G.1    Sharrett, A.R.2    Barnes, R.3
  • 6
    • 0028352793 scopus 로고
    • Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study
    • Kuller L, Borhani N, Furberg C, et al. Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study. Am J Epidemiol 1994;139:1164-79.
    • (1994) Am J Epidemiol , vol.139 , pp. 1164-1179
    • Kuller, L.1    Borhani, N.2    Furberg, C.3
  • 7
    • 0028040275 scopus 로고
    • Relation of carotid artery wall thickness to diabetes mellitus, fasting glucose and insulin, body size, and physical activity
    • Folsom AR, Eckfeldt J, Weitzman S. Relation of carotid artery wall thickness to diabetes mellitus, fasting glucose and insulin, body size, and physical activity. Stroke 1994;25:66-73.
    • (1994) Stroke , vol.25 , pp. 66-73
    • Folsom, A.R.1    Eckfeldt, J.2    Weitzman, S.3
  • 8
    • 0030826182 scopus 로고    scopus 로고
    • Common carotid artery intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study
    • Bots ML, Hoes AW, Koudstaal PJ, et al. Common carotid artery intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation 1997;96:1432-7.
    • (1997) Circulation , vol.96 , pp. 1432-1437
    • Bots, M.L.1    Hoes, A.W.2    Koudstaal, P.J.3
  • 9
    • 0030848434 scopus 로고    scopus 로고
    • Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: The Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993
    • Chambless LE, Heiss G, Folsom AR, et al. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. Am J Epidemiol 1997;146:483-94.
    • (1997) Am J Epidemiol , vol.146 , pp. 483-494
    • Chambless, L.E.1    Heiss, G.2    Folsom, A.R.3
  • 10
    • 0032519844 scopus 로고    scopus 로고
    • The role of carotid arterial intima-media thickness in predicting clinical coronary events
    • Hodis HN, Mack WJ, LaBree L, et al. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med 1998;128:262-9.
    • (1998) Ann Intern Med , vol.128 , pp. 262-269
    • Hodis, H.N.1    Mack, W.J.2    LaBree, L.3
  • 11
    • 0033531215 scopus 로고    scopus 로고
    • Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults: Cardiovascular Health Study Collaborative Research Group
    • O'Leary DH, Polak JF, Kronmal RA, et al. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults: Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999;340:14-22.
    • (1999) N Engl J Med , vol.340 , pp. 14-22
    • O'Leary, D.H.1    Polak, J.F.2    Kronmal, R.A.3
  • 12
    • 0021824223 scopus 로고
    • Role of apolipoprotein E genetic polymorphism in determining normal plasma lipid and lipoprotein variation
    • Sing CF, Davignon J. Role of apolipoprotein E genetic polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet 1985;37:268-85.
    • (1985) Am J Hum Genet , vol.37 , pp. 268-285
    • Sing, C.F.1    Davignon, J.2
  • 13
    • 0022644527 scopus 로고
    • Apolipoprotein E polymorphism in the Finnish population: Gene frequencies and relation to lipoprotein concentrations
    • Ehnholm C, Lukka M, Kuusi T, et al. Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations. J Lipid Res 1986;27:227-35.
    • (1986) J Lipid Res , vol.27 , pp. 227-235
    • Ehnholm, C.1    Lukka, M.2    Kuusi, T.3
  • 14
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988;8:1-21.
    • (1988) Arteriosclerosis , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 15
    • 0025816694 scopus 로고
    • Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health
    • Xhignesse M, Lussier-Cacan S, Sing CF, et al. Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health. Arterioscler Thromb 1991;11:1100-10.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1100-1110
    • Xhignesse, M.1    Lussier-Cacan, S.2    Sing, C.F.3
  • 16
    • 0027418199 scopus 로고
    • Impact of apolipoprotein e polymorphism in determining interindividual variation in total cholesterol and low density lipoprotein cholesterol in Hispanics and non-Hispanic whites
    • Kamboh MI, Aston CE, Ferrell RE, et al. Impact of apolipoprotein E polymorphism in determining interindividual variation in total cholesterol and low density lipoprotein cholesterol in Hispanics and non-Hispanic whites. Atherosclerosis 1993;98:201-11.
    • (1993) Atherosclerosis , vol.98 , pp. 201-211
    • Kamboh, M.I.1    Aston, C.E.2    Ferrell, R.E.3
  • 17
    • 0021347464 scopus 로고
    • Apolipoprotein E phenotypes in patients with myocardial infarction
    • Utermann G, Hardewig A, Zimmer F. Apolipoprotein E phenotypes in patients with myocardial infarction. Hum Genet 1984;65:237-41.
    • (1984) Hum Genet , vol.65 , pp. 237-241
    • Utermann, G.1    Hardewig, A.2    Zimmer, F.3
  • 18
    • 84942951233 scopus 로고
    • Apolipoprotein E alleles, dyslipidemia, and coronary heart disease: The Framingham Offspring Study
    • Wilson PW, Myers RH, Larson MG, et al. Apolipoprotein E alleles, dyslipidemia, and coronary heart disease: the Framingham Offspring Study. JAMA 1994;272:1666-71.
    • (1994) JAMA , vol.272 , pp. 1666-1671
    • Wilson, P.W.1    Myers, R.H.2    Larson, M.G.3
  • 19
    • 0029745022 scopus 로고    scopus 로고
    • Apolipoprotein E polymorphism is associated with segment-specific extracranial carotid artery intima-media thickening
    • Terry JG, Howard G, Mercuri M, et al. Apolipoprotein E polymorphism is associated with segment-specific extracranial carotid artery intima-media thickening. Stroke 1996;27:1755-9.
    • (1996) Stroke , vol.27 , pp. 1755-1759
    • Terry, J.G.1    Howard, G.2    Mercuri, M.3
  • 20
    • 0034466788 scopus 로고    scopus 로고
    • The independent correlation of the impact of lipoprotein(a) levels and apolipoprotein E polymorphism on carotid artery intima thickness
    • Horejsi B, Spacil J, Ceska R, et al. The independent correlation of the impact of lipoprotein(a) levels and apolipoprotein E polymorphism on carotid artery intima thickness. Int Angiol 2000;19:331-6.
    • (2000) Int Angiol , vol.19 , pp. 331-336
    • Horejsi, B.1    Spacil, J.2    Ceska, R.3
  • 21
    • 0033780830 scopus 로고    scopus 로고
    • Apolipoprotein E polymorphism and carotid artery intima-media thickness in a random sample of middle-aged men
    • Ilveskoski E, Loimaala A, Mercuri MF, et al. Apolipoprotein E polymorphism and carotid artery intima-media thickness in a random sample of middle-aged men. Atherosclerosis 2000;153:147-53.
    • (2000) Atherosclerosis , vol.153 , pp. 147-153
    • Ilveskoski, E.1    Loimaala, A.2    Mercuri, M.F.3
  • 22
    • 3142706539 scopus 로고    scopus 로고
    • Meta-analysis: Apolipoprotein E genotypes and risk for coronary heart disease
    • Song Y, Stampfer MJ, Liu S. Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease. Ann Intern Med 2004;141:137-47.
    • (2004) Ann Intern Med , vol.141 , pp. 137-147
    • Song, Y.1    Stampfer, M.J.2    Liu, S.3
  • 23
    • 0024591825 scopus 로고
    • The Atherosclerosis Risk in Communities (ARIC) Study: Design and objectives
    • The ARIC investigators
    • The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. Am J Epidemiol 1989;129:687-702.
    • (1989) Am J Epidemiol , vol.129 , pp. 687-702
  • 24
    • 0030465255 scopus 로고    scopus 로고
    • Differences between respondents and non-respondents in a multi-center community-based study vary by gender and ethnicity
    • Jackson R, Chambless LE, Yang K, et al. Differences between respondents and non-respondents in a multi-center community-based study vary by gender and ethnicity. J Clin Epidemiol 1996;49:1441-6.
    • (1996) J Clin Epidemiol , vol.49 , pp. 1441-1446
    • Jackson, R.1    Chambless, L.E.2    Yang, K.3
  • 25
    • 0029976359 scopus 로고    scopus 로고
    • Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: Methods and initial 2 years' experience
    • White A, Folsom A, Chambless L, et al. Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial 2 years' experience. J Clin Epidemiol 1996;49:223-33.
    • (1996) J Clin Epidemiol , vol.49 , pp. 223-233
    • White, A.1    Folsom, A.2    Chambless, L.3
  • 26
    • 0020539888 scopus 로고
    • Reagent for the enzymatic determination of serum total cholesterol with improved lipolytic efficiency
    • Siedel J, Hagele EO, Ziegenhorn J, et al. Reagent for the enzymatic determination of serum total cholesterol with improved lipolytic efficiency. Clin Chem 1983;29:1075-85.
    • (1983) Clin Chem , vol.29 , pp. 1075-1085
    • Siedel, J.1    Hagele, E.O.2    Ziegenhorn, J.3
  • 27
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein in plasma, without use of preparative ultracentrifuge
    • Friedwald WT, Levy RI, Frederickson DS. Estimation of the concentration of low-density lipoprotein in plasma, without use of preparative ultracentrifuge. Clin Chem 1972;18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedwald, W.T.1    Levy, R.I.2    Frederickson, D.S.3
  • 28
    • 0000751086 scopus 로고
    • Quantitation of highdensity lipoprotein subclasses after separation by dextran sulfate and Mg2+ precipitation
    • Warnick GR, Benderson JM, Albers JJ. Quantitation of highdensity lipoprotein subclasses after separation by dextran sulfate and Mg2+ precipitation. (Abstract). Clin Chem 1982;28:1574.
    • (1982) Clin Chem , vol.28 , pp. 1574
    • Warnick, G.R.1    Benderson, J.M.2    Albers, J.J.3
  • 29
    • 84910922375 scopus 로고
    • High-resolution B-mode ultrasound scanning methods in the Atherosclerosis Risk in Communities Study (ARIC)
    • The ARIC Study Group
    • High-resolution B-mode ultrasound scanning methods in the Atherosclerosis Risk in Communities Study (ARIC). The ARIC Study Group. J Neuroimaging 1991;1:68-73.
    • (1991) J Neuroimaging , vol.1 , pp. 68-73
  • 30
    • 0032520896 scopus 로고    scopus 로고
    • Body weight change and carotid artery wall thickness: The Atherosclerosis Risk in Communities (ARIC) Study
    • Stevens J, Tyroler HA, Cai J, et al. Body weight change and carotid artery wall thickness: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Epidemiol 1998;147:563-73.
    • (1998) Am J Epidemiol , vol.147 , pp. 563-573
    • Stevens, J.1    Tyroler, H.A.2    Cai, J.3
  • 31
    • 0029900106 scopus 로고    scopus 로고
    • Variability in B-mode ultrasound measurements in the Atherosclerosis Risk in Communities (ARIC) Study
    • Chambless LE, Zhong MM, Arnett D, et al. Variability in B-mode ultrasound measurements in the Atherosclerosis Risk in Communities (ARIC) Study. Ultrasound Med Biol 1996;22:545-54.
    • (1996) Ultrasound Med Biol , vol.22 , pp. 545-554
    • Chambless, L.E.1    Zhong, M.M.2    Arnett, D.3
  • 32
    • 0036090623 scopus 로고    scopus 로고
    • Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: NHLBI Family Heart Study
    • Djousse L, Myers RH, Province MA, et al. Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: NHLBI Family Heart Study. Stroke 2002;33:1357-61.
    • (2002) Stroke , vol.33 , pp. 1357-1361
    • Djousse, L.1    Myers, R.H.2    Province, M.A.3
  • 33
    • 0037383551 scopus 로고    scopus 로고
    • Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: Results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
    • Beilby JP, Hunt CCJ, Palmer LJ, et al. Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS). Stroke 2003;34:869-74.
    • (2003) Stroke , vol.34 , pp. 869-874
    • Beilby, J.P.1    Hunt, C.C.J.2    Palmer, L.J.3
  • 34
    • 0042823560 scopus 로고    scopus 로고
    • Mortality and apolipoprotein E in African-American and white elders: An attempted replication
    • Fillenbaum GG, Burchett BM, Lee JH, et al. Mortality and apolipoprotein E in African-American and white elders: an attempted replication. Am J Med Genet A 2003;119:141-6.
    • (2003) Am J Med Genet A , vol.119 , pp. 141-146
    • Fillenbaum, G.G.1    Burchett, B.M.2    Lee, J.H.3
  • 35
    • 16644370972 scopus 로고    scopus 로고
    • Association of APOE genotype with carotid atherosclerosis in men and women: The Framingham Heart Study
    • Elosua R, Ordovas JM, Cupples LA, et al. Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study. J Lipid Res 2004;45:1868-75.
    • (2004) J Lipid Res , vol.45 , pp. 1868-1875
    • Elosua, R.1    Ordovas, J.M.2    Cupples, L.A.3
  • 36
    • 0034820210 scopus 로고    scopus 로고
    • Apolipoprotein E and carotid artery atherosclerosis: The Rotterdam Study
    • Slooter AJC, Bots ML, Havekes LM, et al. Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam Study. Stroke 2001;32:1947-52.
    • (2001) Stroke , vol.32 , pp. 1947-1952
    • Slooter, A.J.C.1    Bots, M.L.2    Havekes, L.M.3
  • 37
    • 0029057476 scopus 로고
    • Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis
    • de Andrade M, Thandi I, Brown S, et al. Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis. Am J Hum Genet 1995;56:1379-90.
    • (1995) Am J Hum Genet , vol.56 , pp. 1379-1390
    • De Andrade, M.1    Thandi, I.2    Brown, S.3
  • 38
    • 0029019338 scopus 로고
    • No association between plasma lipoprotein(a) concentrations and the presence or absence of coronary atherosclerosis in African-Americans
    • Moliterno DJ, Jokinen EV, Miserez AR, et al. No association between plasma lipoprotein(a) concentrations and the presence or absence of coronary atherosclerosis in African-Americans. Arterioscler Thromb Vasc Biol 1995;15:850-5.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 850-855
    • Moliterno, D.J.1    Jokinen, E.V.2    Miserez, A.R.3
  • 39
    • 0035806916 scopus 로고    scopus 로고
    • Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: The Atherosclerosis Risk in Communities (ARIC) Study
    • Sharrett AR, Ballantyne CM, Coady SA, et al. Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 2001;104:1108-13.
    • (2001) Circulation , vol.104 , pp. 1108-1113
    • Sharrett, A.R.1    Ballantyne, C.M.2    Coady, S.A.3
  • 40
    • 0001575895 scopus 로고
    • Type III hyperlipoproteinemia (dys-betalipoproteinemia): The role of apolipoprotein E in normal and abnormal lipoprotein metabolism
    • Scriver CR, Beaudet AL, Sly WS, et al, eds. New York, NY: McGraw-Hill
    • Mahley RW, Rall SC Jr. Type III hyperlipoproteinemia (dys- betalipoproteinemia): the role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: Scriver CR, Beaudet AL, Sly WS, et al, eds. The metabolic and molecular bases of inherited disease. Vol II. New York, NY: McGraw-Hill, 1995:1953-80.
    • (1995) The Metabolic and Molecular Bases of Inherited Disease , vol.2 , pp. 1953-1980
    • Mahley, R.W.1    Rall Jr., S.C.2


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