Large animal models of fulminant hepatic failure in artificial and bioartificial liver support research

Biomaterials

Volumn 25, Issue 9, 2004, Pages 1613-1625

  Van De Kerkhove, M P ^a   Hoekstra, R ^a   Van Gulik, T M ^a   Chamuleau, R A F M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Animal model; Bioartificial liver; Bioreactor; Dog; Liver failure; Pig

Indexed keywords

BIOLOGICAL ORGANS; PATIENT TREATMENT; PHYSIOLOGICAL MODELS; SAFETY TESTING; TISSUE;

LIVER SUPPORT SYSTEMS;

BIOMATERIALS;

AMMONIA; ATROPINE; HALOTHANE; KETAMINE; MIDAZOLAM; PANCURONIUM BROMIDE; PARACETAMOL;

ARTIFICIAL LIVER; BIOARTIFICIAL ORGAN; BIOREACTOR; BLOOD VESSEL; BRAIN EDEMA; CARDIOTOXICITY; CARTILAGE; CLINICAL TRIAL; DRUG INTOXICATION; EXPERIMENTAL ANIMAL; EXTRACORPOREAL CIRCULATION; GRAFT FAILURE; HUMAN; ISCHEMIA; LIVER FAILURE; LIVER FUNCTION; LIVER GRAFT; LIVER REGENERATION; LIVER TOXICITY; LIVER TRANSPLANTATION; LUNG INJURY; METHEMOGLOBINEMIA; NEPHROTOXICITY; NONHUMAN; PARTIAL HEPATECTOMY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REVIEW; SAFETY; SKIN; TISSUE ENGINEERING; TISSUE NECROSIS;

ANIMALIA; CANIS FAMILIARIS; SUS SCROFA;

EID: 0347124671     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(03)00509-X     Document Type: Article

References (104)

1. Fruhauf N.R., Kaiser G.M., Nosser S.A., Bader A., Oldhafer K.J. Large animal models for testing bioartificial liver support systems. Biomed Sci Instrum. 37:2001;511-516.
2. Terblanche J., Hickman R. Animal models of fulminant hepatic failure. Dig Dis Sci. 36(6):1991;770-774.
3. Newsome P.N., Plevris J.N., Nelson L.J., Hayes P.C. Animal models of fulminant hepatic failure. a critical evaluation Liver Transplant. 6(1):2000;21-31.
4. Rahman T.M., Hodgson H.J. Animal models of acute hepatic failure. Int J Exp Pathol. 81(2):2000;145-157.
5. Filipponi F., Mosca F. Animal models of fulminant hepatic failure. need to test liver support devices Dig Liver Dis. 33(7):2001;607-613.
6. Tessier G., Villeneuve E., Villeneuve J.P. Etiology and outcome of acute liver failure. experience from a liver transplantation centre in Montreal Can J Gastroenterol. 16(10):2002;672-676.
7. Gill R.Q., Sterling R.K. Acute liver failure. J Clin Gastroenterol. 33(3):2001;191-198.
8. Shakil A.O., Kramer D., Mazariegos G.V., Fung J.J., Rakela J. Acute liver failure. clinical features, outcome analysis, and applicability of prognostic criteria Liver Transplant. 6(2):2000;163-169.
9. Capocaccia L., Angelico M. Fulminant hepatic failure. Clinical features, etiology, epidemiology, and current management. Dig Dis Sci. 36(6):1991;775-779.
10. Bernuau J., Rueff B., Benhamou J.P. Fulminant and subfulminant liver failure. definitions and causes Semin Liver Dis. 6(2):1986;97-106.
11. Conn H.O., Lieberthal M.M. The hepatic coma syndromes and lactulose. 1979;University Park Press, Baltimore.
12. Schafer D.F., Shaw B.W. Jr. Fulminant hepatic failure and orthotopic liver transplantation. Semin Liver Dis. 9(3):1989;189-194.
13. Bass N.M. Monitoring and treatment of intracranial hypertension. Liver Transplant. 6(4 Suppl. 1):2000;S21-S26.
14. Moore K. Renal failure in acute liver failure. Eur J Gastroenterol Hepatol. 11(9):1999;967-975.
15. Bernuau J., Benhamou J.P. Fulminant and subfulminant liver failure. Mc Intyre N., Benhamou J.P., Bircher J., Rizzetto M., Rodes J. Oxford textbook of clinical hepatology. 1991;923-942 Oxford University Press, Oxford, New York, Tokyo.
16. Adam R., Cailliez V., Majno P., Karam V., McMaster P., Caine R.Y.et al. Normalised intrinsic mortality risk in liver transplantation. European liver transplant registry study Lancet. 356(9230):2000;621-627.
17. Lidofsky S.D., Bass N.M., Prager M.C., Washington D.E., Read A.E., Wright T.L.et al. Intracranial pressure monitoring and liver transplantation for fulminant hepatic failure. Hepatology. 16(1):1992;1-7.
18. De Rave S., Tilanus H.W., van der Linden J., de Man R.A., van der Berg B., Hop W.J.et al. The importance of orthotopic liver transplantation in acute hepatic failure. Transpl Int. 15(1):2002;29-33.
19. Wall W.J., Adams P.C. Liver transplantation for fulminant hepatic failure. North American experience Liver Transpl Surg. 1(3):1995;178-182.
20. United Network for Organ Sharing. Liver transplantation data 2002; www.unos.org.
21. Palmes D., Qayumi A.K., Spiegel H.U. Liver bridging techniques in the treatment of acute liver failure. J Invest Surg. 13(6):2000;299-311.
22. Stange J., Hassanein T.I., Mehta R., Mitzner S.R., Bartlett R.H. The molecular adsorbents recycling system as a liver support system based on albumin dialysis. a summary of preclinical investigations, prospective, randomized, controlled clinical trial, and clinical experience from 19 centers Artif Organs. 26(2):2002;103-110.
23. Schachschal G., Morgera S., Kupferling S., Neumayer H.H., Lochs H., Schmidt H.H. Emerging indications for MARS dialysis. Liver. 22(2):2002;63-68.
24. Steiner C., Mitzner S. Experiences with MARS liver support therapy in liver failure. analysis of 176 patients of the international mars registry Liver. 22(2):2002;20-25.
25. van de Kerkhove MP, Hoekstra R, van Gulik TM, Chamuleau RA. MARS treatment in posthepatectomy liver failure. Liver International, in press.
26. Seige M., Kreymann B., Jeschke B., Schweigart U., Kopp K.F., Classen M. Long-term treatment of patients with acute exacerbation of chronic liver failure by albumin dialysis. Transplant Proc. 31(1-2):1999;1371-1375.
27. Ash S.R. Extracorporeal blood detoxification by sorbents in treatment of hepatic encephalopathy. Adv Renal Replace Ther. 9(1):2002;3-18.
28. Lanjuan L., Qian Y., Jianrong H., Xiaowei X., Yuemei C., Yagang C.et al. Severe hepatitis treated with an artificial liver support system. Int J Artif Organs. 24(5):2001;297-303.
29. van de Kerkhove M.P., Chamuleau R.A.F.M., van Gulik T.M. Clincial application of bioartificial liver support systems. Jones E.A., Meijer A.J., Chamuleau R.A.F.M. Encephalopathy and nitrogen metabolism in liver failure. vol. 38:2003;389-414 Kluwer Academic Publishers, Dordrecht. [Review].
30. Ellis A.J., Hughes R.D., Wendon J.A., Dunne J., Langley P.G., Kelly J.H.et al. Pilot-controlled trial of the extracorporeal liver assist device in acute liver failure. Hepatology. 24(6):1996;1446-1451.
31. Watanabe F.D., Mullon C.J., Hewitt W.R., Arkadopoulos N., Kahaku E., Eguchiet al. Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial. Ann Surg. 225(5):1997;484-491.
32. Xue Y.L., Zhao S.F., Luo Y., Li X.J., Duan Z.P., Chen X.P.et al. TECA hybrid artificial liver support system in treatment of acute liver failure. World J Gastroenterol. 7(6):2001;826-829.
33. Mazariegos G.V., Kramer D.J., Lopez R.C., Shakil A.O., Rosenbloom A.J., DeVera M.et al. Safety observations in phase I clinical evaluation of the Excorp Medical Bioartificial Liver Support System after the first four patients. ASAIO J. 47(5):2001;471-475.
34. Morsiani E., Pazzi P., Puviani A.C., Brogli M., Valieri L., Gorini P.et al. Early experiences with a porcine hepatocyte-based bioartificial liver in acute hepatic failure patients. Int J Artif Organs. 25(3):2002;192-202.
35. Mundt A., Puhl G., Muller A., Sauer I., Muller C., Richard R.et al. A method to assess biochemical activity of liver cells during clinical application of extracorporeal hybrid liver support. Int J Artif Organs. 25(6):2002;542-548.
36. Donini A., Baccarani U., Risaliti A., Degrassi A., Bresadola F. Temporary neurological improvement in a patient with acute or chronic liver failure treated with a bioartificial liver device. Am J Gastroenterol. 95(4):2000;1102-1104.
37. van de Kerkhove M.P., Di Florio E., Scuderi V., Mancini A., Belli A., Bracco A.et al. Phase I clinical trial with the AMC-bioartificial liver. Academic Medical Center. Int J Artif Organs. 25(10):2002;950-959.
38. Fourneau I. A potential reversible model of acute liver failure in the pig; a model to test the efficiency of a bioartificial liver. Thesis, University of Leuven, 2001. p. 41-56.
39. Janke J., Gerlach J., Kardassis D., Bohmer C., Rossaint R. Effect of a hybrid liver support system on cardiopulmonary function in healthy pigs. Int J Artif Organs. 20(10):1997;570-575.
40. Sosef M.N., Abrahamse L.S., van de Kerkhove M.P., Hartman R., Chamuleau R.A., van Gulik T.M. Assessment of the AMC-bioartificial liver in the anhepatic pig. Transplantation. 73(2):2002;204-209.
41. Fourneau I., Pirenne J., Roskams T., Yap S.H. An improved model of acute liver failure based on transient ischemia of the liver. Arch Surg. 135(10):2000;1183-1189.
42. Kelly J.H., Koussayer T., He D., Chong M.G., Shang T.A., Whisennand H.H.et al. Assessment of an extracorporeal liver assist device in anhepatic dogs. Artif Organs. 16(4):1992;418-422.
43. Gerlach J., Trost T., Ryan C.J., Meissler M., Hole O., Muller C.et al. Hybrid liver support system in a short term application on hepatectomized pigs. Int J Artif Organs. 17(10):1994;549-553.
44. Rozga J., Williams F., Ro M.S., Neuzil D.F., Giorgio T.D., Backfisch G. et al. Development of a bioartificial liver. properties and function of a hollow-fiber module inoculated with liver cells Hepatology. 17(2):1993;258-265.
45. Kahn D., Hickman R., Terblanche J., Von Sommoggy S. Partial hepatectomy and liver regeneration in pigs - the response to different resection sizes. J Surg Res. 45(2):1988;176-180.
46. Filipponi F., Fabbri L.P., Marsili M., Falcini F., Benassai C., Nucera M.et al. A new surgical model of acute liver failure in the pig. experimental procedure and analysis of liver injury Eur Surg Res. 23(1):1991;58-64.
47. Chen X.P., Xue Y.L., Li X.J., Zhang Z.Y., Li Y.L., Huang Z.Q. Experimental research on TECA-I bioartificial liver support system to treat canines with acute liver failure. World J Gastroenterol. 7(5):2001;706-709.
48. Karrer F.M., Rhenman B., Buckley A.R., Steinbronn K.K., Putnam C.W. A reproducible large animal model of acute hepatic failure. Curr Surg. 41(6):1984;464-467.
49. Tonnesen K. Experimental liver failure. A comparison between hepatectomy and hepatic devascularization in the pig. Acta Chir Scand. 143(5):1977;271-277.
50. Bozzetti F., Gennari L., Regalia E., Bignami P., Montalto F., Mazzaferro V.et al. Morbidity and mortality after surgical resection of liver tumors. Analysis of 229 cases. Hepatogastroenterology. 39(3):1992;237-241.
51. Shirabe K., Shimada M., Gion T., Hasegawa H., Takenaka K., Utsunomiya T.et al. Postoperative liver failure after major hepatic resection for hepatocellular carcinoma in the modern era with special reference to remnant liver volume. J Am Coll Surg. 188(3):1999;304-309.
52. Farges O., Malassagne B., Flejou J.F., Balzan S., Sauvanet A., Belghiti J. Risk of major liver resection in patients with underlying chronic liver disease. a reappraisal Ann Surg. 229(2):1999;210-215.
53. Dinant S, Van Vliet AK, Straatsburg IH, van Gulik TM. FLEXICOR study. Unpublished work, Academic Medical Center, Amsterdam, 2002.
54. Mann J.C. Studies in the physiology of the liver. I. Technique and general effects of removal. Am J Med Sci. 161:1921;37.
55. Markowitz J., Soskin S. A simplified technique for hepatectomy. Proc Soc Exp Biol Med. 25:1927;7.
56. Firor W., Stinson E. Total extirpation of dog liver in one stage. Bull John Hupkins Hosp. 44:1929;138.
57. Grindlay F.H., Mann F.C. Removal of liver of dog. Experimental surgical technique. Surgery. 31:1952;900.
58. Starzl T.E., Bernharce V.M., Benvemuter R., Cortes M. A new method for one-stage hepatectomy in dogs. Surgery. 46:1959;880.
59. Hickman R., Saunders S.J., Terblanche J. Liver function in the pig. Total hepatic and portal flow values in vivo. S Afr Med J. 48(28):1974;1197- 1200.
60. Klotzer B., Staffa G., Keitel R., Balster U., Walter F. Animal model for the study of the anhepatic state. Z Exp Chir. 10(4):1977;188-191.
61. Thompson J.F., Bell R., Bookallil M.J., Sheil A.G. Effects of total hepatectomy. studies in a porcine model Aust N Z J Surg. 64(8):1994;560-564.
62. Filipponi F., Boggi U., Meacci L., Burchielli S., Vistoli F., Bellini R.et al. A new technique for total hepatectomy in the pig for testing liver support devices. Surgery. 125(4):1999;448-455.
63. Ringe B., Pichlmayr R., Ziegler H., Grosse H., Kuse E., Oldhafer K.et al. Management of severe hepatic trauma by two-stage total hepatectomy and subsequent liver transplantation. Surgery. 109(6):1991;792-795.
64. Ringe B., Pichlmayr R., Lubbe N., Bornscheuer A., Kuse E. Total hepatectomy as temporary approach to acute hepatic or primary graft failure. Transplant Proc. 20(1 Suppl. 1):1988;552-557.
65. Ringe B., Lubbe N., Kuse E., Frei U., Pichlmayr R. Total hepatectomy and liver transplantation as two-stage procedure. Ann Surg. 218(1):1993;3-9.
66. de Groot G.H., Reuvers C.B., Schalm S.W., Boks A.L., Terpstra O.T., Jeekel H.et al. A reproducible model of acute hepatic failure by transient ischemia in the pig. J Surg Res. 42(1):1987;92-100.
67. Ytrebo L.M., Nedredal G.I., Langbakk B., Revhaug A. An experimental large animal model for the assessment of bioartificial liver support systems in fulminant hepatic failure. Scand J Gastroenterol. 37(9):2002;1077-1088.
68. Benoist S., Sarkis R., Baudrimont M., Delelo R., Robert A., Vaubourdolle M.et al. A reversible model of acute hepatic failure by temporary hepatic ischemia in the pig. J Surg Res. 88(2):2000;63-69.
69. Nakazawa K., Ijima H., Fukuda J., Sakiyama R., Yamashita Y., Shimada M. et al. Development of a hybrid artificial liver using polyurethane foam/hepatocyte spheroid culture in a preclinical pig experiment. Int J Artif Organs. 25(1):2002;51-60.
70. Awad S.S., Hemmila M.R., Soldes O.S., Sawada S., Rich P.B., Mahler S.et al. A novel stable reproducible model of hepatic failure in canines. J Surg Res. 94(2):2000;167-171.
71. Enosawa S., Miyashita T., Fujita Y., Suzuki S., Amemiya H., Omasa T.et al. In vivo estimation of bioartificial liver with recombinant HepG2 cells using pigs with ischemic liver failure. Cell Transplant. 10(4-5):2001;429-433.
72. Argibay P., Vazquez J., Barros P., Verge D., Nunez F., Garcia H.et al. Extracorporeal auxiliary xenoperfusion. animal model of support in fulminant liver failure Transplant Proc. 28(2):1996;749-750.
73. Flendrig L.M., Calise F., Di Florio E., Mancini A., Ceriello A., Santaniello W.et al. Significantly improved survival time in pigs with complete liver ischemia treated with a novel bioartificial liver. Int J Artif Organs. 22(10):1999;701-709.
74. Hanid M.A., Mackenzie R.L., Jenner R.E., Chase R.A., Mellon P.J., Trewby P.N.et al. Intracranial pressure in pigs with surgically induced acute liver failure. Gastroenterology. 76(1):1979;123-131.
75. Weston M.J., Gazzard B.G., Buxton B.H., Winch J., Machado A.L., Flax H. et al. Effects of haemoperfusion through charcoal or XAD-2 resin on an animal model of fulminant liver failure. Gut. 15(6):1974;482-486.
76. Rappaport A.M., Malcolm H., MacDonald H.et al. Hepatic coma following ischemia of the liver. Surg Gynecol Obstet. 97:1953;763-768.
77. Rappaport AM. Experimental ischemia of the liver, hepatic coma. Transactions of 10th Liver Injury Conferences, Josiah Macy Jr. Foundation, New York, 1951. p. 146-79.
78. Giges B., Dein D.H., Sborov V.M., Seligson D., Howard J.M. Experimental hepatic coma. Gynecol Obstet. 97:1953;763-769.
79. Huguet C., Opolon P., Blocj P., Gallot D., Morisot P., Hadchouel P. Coma hepatique experimental par necrose ischemique aigue du foie chez le porc. J Chir. 103:1972;63-76.
80. Sielaff T.D., Hu M.Y., Rollins M.D., Bloomer J.R., Amiot B., Hu W.S.et al. An anesthetized model of lethal canine galactosamine fulminant hepatic failure. Hepatology. 21(3):1995;796-804.
81. Diaz-Buxo J.A., Blumenthal S., Hayes D., Gores P., Gordon B. Galactosamine-induced fulminant hepatic necrosis in unanesthetized canines. Hepatology. 25(4):1997;950-957. [see comments].
82. Kalpana K., Ong H.S., Soo K.C., Tan S.Y., Prema R.J. An improved model of galactosamine-induced fulminant hepatic failure in the pig. J Surg Res. 82(2):1999;121-130.
83. Patzer J.F., Mazariegos G.V., Lopez R. Preclinical evaluation of the Excorp Medical, Inc, Bioartificial Liver Support System. J Am Coll Surg. 195(3):2002;299-310.
84. Plevris J.N., Schina M., Hayes P.C. Review article. the management of acute liver failure Aliment Pharmacol Ther. 12(5):1998;405-418. [Review] [120 refs].
85. Miller D.J., Hickman R., Fratter R., Terblanche J., Saunders S.J. An animal model of fulminant hepatic failure. a feasibility study Gastroenterology. 71(1):1976;109-113.
86. Francavilla A., Makowka L., Polimeno L., Barone M., Demetris J., Prelich J.et al. A dog model for acetaminophen-induced fulminant hepatic failure. Gastroenterology. 96(2 Part 1):1989;470-478.
87. Kelly J.H., Koussayer T., He D.E., Chong M.G., Shang T.A., Whisennand H.H.et al. An improved model of acetaminophen-induced fulminant hepatic failure in dogs. Hepatology. 15(2):1992;329-335.
88. Gazzard B.G., Hughes R.D., Mellon P.J., Portmann B., Williams R. A dog model of fulminant hepatic failure produced by paracetamol administration. Br J Exp Pathol. 56(5):1975;408-411.
89. Hickman R., Alp M.H. A predictable pathophysiological model of porcine hepatic failure. Eur Surg Res. 18(5):1986;283-292.
90. Clemmesen J.O., Larsen F.S., Kondrup J., Hansen B.A., Ott P. Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration. Hepatology. 29(3):1999;648-653.
91. Muting D., Kalk J.F., Koussouris P., Motschenbacher M.T., Rausche A. The role of protein metabolism in 204 liver cirrhotics with and without hepatic encephalopathy. I. Clinical and general biochemical findings. Hepatogastroenterology. 33(2):1986;61-65.
92. Husberg B.S., Goldstein R.M., Klintmalm G.B., Gonwa T., Ramsay M., Cofer J.et al. A totally failing liver may be more harmful than no liver at all. three cases of total hepatic devascularization in preparation for emergency liver transplantation Transplant Proc. 23(1 Part 2):1991;1533-1535.
93. Ringe B., Lubbe N., Kuse E., Frei U., Pichlmayr R. Total hepatectomy and liver transplantation as two-stage procedure. Ann Surg. 218(1):1993;3-9.
94. Oldhafer K.J., Bornscheuer A., Fruhauf N.R., Frerker M.K., Schlitt H.J., Ringe B.et al. Rescue hepatectomy for initial graft non-function after liver transplantation. Transplantation. 67(7):1999;1024-1028.
95. Mazziotti A., Bernardi M., Antonini L., Dioguardi F.S., Bellusci R., Papaet al. Plasma amino acid patterns in experimental acute hepatic failure. comparison between hepatectomy and liver devascularization in pigs Surgery. 90(3):1981;527-534.
96. Theodoraki K., Kostopanagiotou G., Smyrniotis V., Arkadopoulos N., Prachalias A., Pyrsopoulos N.et al. Haemodynamic changes in ischaemic vs. anhepatic pig experimental model of acute liver failure. Eur J Anaesthesiol. 19(1):2002;40-46.
97. Lee W.M. Total hepatectomy for acute liver failure. don't take out my liver! Gastroenterology. 107(3):1994;894-897.
98. Khalili T.M., Navarro A., Ting P., Kamohara Y., Arkadopoulos N., Solomon B.A.et al. Bioartificial liver treatment prolongs survival and lowers intracranial pressure in pigs with fulminant hepatic failure. Artif Organs. 25(7):2001;566-570.
99. 2, and pH during hypo- and hyperventilation at constant mean airway pressure in pigs. Intensive Care Med. 28(1):2002;68-73.
100. Ytrebo L.M., Korvald C., Nedredal G.I., Elvenes O.P., Nielsen Grymyr O.J., Revhaug A. N-acetylcysteine increases cerebral perfusion pressure in pigs with fulminant hepatic failure. Crit Care Med. 29(10):2001;1989-1995.
101. Flecknell P.A. Laboratory animal anaesthesia. 2nd ed:2002;Academic Press Harcourt Brace & Company Publishers, San Diego.
102. Jalan R., Damink S.W., Deutz N.E., Lee A., Hayes P.C. Moderate hypothermia for uncontrolled intracranial hypertension in acute liver failure. Lancet. 354(9185):1999;1164-1168.
103. Norton N.S., McConnell J.R., Rodriguez-Sierra J.F. Behavioral and physiological sex differences observed in an animal model of fulminant hepatic encephalopathy in the rat. Physiol Behav. 62(5):1997;1113-1124.
104. Osanai T., Miyoshi I., Hiramune T., Kasai N. Spontaneous urinary calculus in young LEW rats caused by corynebacterium renale. J Urol. 152(3):1994;1002-1004.