In vitro evaluation of a multi-layer radial-flow bioreactor based on galactosylated chitosan nanofiber scaffolds

Biomaterials

Volumn 30, Issue 27, 2009, Pages 4533-4538

  Chu, Xue Hui ^a   Shi, Xiao Lei ^a   Feng, Zhang Qi ^b   Gu, Jin Yang ^a   Xu, Hai Yun ^a   Zhang, Yue ^a   Gu, Zhong Ze ^b   Ding, Yi Tao ^a  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b SOUTHEAST UNIVERSITY   (China)

Author keywords

Bioartificial liver; Bioreactor; Chitosan; Hepatocyte; Nanotopography

Indexed keywords

BIOARTIFICIAL LIVER; CLINICAL USE; CULTURE MEDIUM; FLAT PLATE; GALACTOSYLATED CHITOSAN; HEPATOCYTE; HEPATOCYTES; IN-VITRO; IN-VITRO EVALUATION; NANOFIBER SCAFFOLD; NANOTOPOGRAPHY; OXYGEN CONSUMPTION RATE; RADIAL-FLOW BIOREACTORS; RED BLOOD CELL;

ADHESION; BIOREACTORS; BLOOD; CELL ADHESION; CELL CULTURE; CELL MEMBRANES; CHITIN; CHITOSAN; INDUSTRIAL CHEMICALS; LIVER; METABOLISM; NANOFIBERS; NANOTECHNOLOGY; OXYGEN; RADIAL FLOW; SCAFFOLDS; UREA;

BIOCONVERSION;

CHITOSAN; MOLECULAR SCAFFOLD; NANOFIBER; OXYGEN; UREA;

ANIMAL CELL; ARTICLE; ARTIFICIAL LIVER; BIOREACTOR; CELL ADHESION; CELL FUNCTION; CONTROLLED STUDY; CULTURE MEDIUM; ERYTHROCYTE; IMMOBILIZED CELL; IN VITRO STUDY; LIVER CELL; METABOLISM; NONHUMAN; OXYGEN CONSUMPTION; PERFUSION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SCANNING ELECTRON MICROSCOPY; SWINE;

ANIMALS; BIOREACTORS; CELL COUNT; CELL SURVIVAL; CHITOSAN; GALACTOSE; GLYCOSYLATION; HEPATOCYTES; NANOSTRUCTURES; ORGAN SPECIFICITY; OXYGEN; OXYGEN CONSUMPTION; RHEOLOGY; SUS SCROFA; TISSUE SCAFFOLDS;

SUIDAE;

EID: 67651152587     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.05.020     Document Type: Article

References (41)

1. Cattral M.S., and Levy G.A. Artificial liver support-pipe dream or reality. N Engl J Med 331 4 (1994) 268-269
2. Onodera K., Sakata H., Yonekawa M., and Kawamura A. Artificial liver support at present and in the future. J Artif Organs 9 1 (2006) 17-28
3. Ellis A.J., Hughes R.D., Wendon J.A., Dunne J., Langley P.G., Kelly J.H., et al. Pilot-controlled trial of the extracorporeal liver assist device in acute liver failure. Hepatology 24 6 (1996) 1446-1451
4. Cho C.S., Seo S.J., and Park I.K. Galactose-carrying polymers as extracellular matrices for liver tissue engineering. Biomaterials 27 4 (2006) 576-585
5. Hong Z., Zhang P., He C., Qiu X., Liu A., Chen L., et al. Nano-composite of poly(l-lactide) and surface grafted hydroxyapatite: mechanical properties and biocompatibility. Biomaterials 26 (2005) 6296-6304
6. Ghasemi-Mobarakeh L., Prabhakaran M.P., Morshed M., Nasr-Esfahani M.H., and Ramakrishna S. Electrospun poly(epsilon-caprolactone)/gelatin nanofibrous scaffolds for nerve tissue engineering. Biomaterials 29 34 (2008) 4532-4539
7. Dégano I.R., Quintana L., Vilalta M., Horna D., Rubio N., Borrós S., et al. The effect of self-assembling peptide nanofiber scaffolds on mouse embryonic fibroblast implantation and proliferation. Biomaterials 30 6 (2009) 1156-1165
8. Wang H., Li Y., Zuo Y., Li J., Ma S., and Cheng L. Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering. Biomaterials 28 22 (2007 Aug) 3338-3348
9. Yang F., Murugan R., Ramakrishna S., Wang X., Ma Y.X., and Wang S. Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering. Biomaterials 25 10 (2004 May) 1891-1900
10. Pattison M.A., Wurster S., and Webster T.J. Three-dimensional, nano-structured PLGA scaffolds for bladder tissue replacement applications. Biomaterials 26 (2005) 2491-2500
11. Chu X.H., Shi X.L., Feng Z.Q., Gu Z.Z., and Ding Y.T. Chitosan nanofiber scaffold enhances hepatocyte adhesion and function. Biotechnol Lett 31 3 (2009 Mar) 347-352
12. Weigel P.H. Rat hepatocytes bind to synthetic galactoside surface via a patch of asialoglycoprotein receptors. J Cell Biol 87 (1980) 855-861
13. Kobayashi A., Akaike T., Kobayashi K., and Sumitomo H. Enhanced adhesion and survival efficacy of liver cells in culture dishes coated with a lactose-carrying styrene homopolymer. Macromol Chem Rapid Commun 7 (1986) 645-650
14. Gutsche A.T., Parsons-Wingerter P., Chand D., Saltzman W.M., Saltzman W.M., and Leong K.W. N-acetyl glucosamine and adenosine derivatized surfaces for cell culture: 3T3 fibroblast and chicken hepatocyte response. Biotechnol Bioeng 43 8 (1994) 801-809
15. Yin C., Ying L., Zhang P.C., Zhuo R.X., Kang E.T., Leong K.W., et al. High density of immobilized galactose ligand enhances hepatocyte attachment and function. J Biomed Mater Res 67A 4 (2003) 1093-1104
16. Ying L., Yin C., Zhuo R.X., Leong K.W., Mao H.Q., Kang E.T., et al. Immobilization of galactose ligands on acrylic acid graft copolymerized poly(ethylene terephthalate) film and its application to hepatocyte culture. Biomacromolecules 4 1 (2003) 157-165
17. Tong J.Z., De Lagausie P., Furlan V., Cresteil T., Bernard O., and Alvarez F. Long-term culture of adult rat hepatocyte spheroids. Exp Cell Res 200 2 (1992) 326-332
18. Yang J., Chung T.W., Nagaoka M., Goto M., Cho C.S., and Akaike T. Hepatocyte-specific porous polymer-scaffolds of alginate/galactosylated chitosan sponge for liver tissue engineering. Biotechnol Lett 23 17 (2001) 1385-1389
19. Yang J., Goto M., Ise H., Cho C.S., and Akaike T. Galactosylated alginate as a scaffold for hepatocytes entrapment. Biomaterials 23 2 (2002) 471-479
20. Seo S.J., Akaike T., Choi Y.J., Shirakawa M., Kang I.K., and Cho C.S. Alginate microcapsules prepared with xyloglucan as a synthetic extracellular matrix for hepatocyte attachment. Biomaterials 26 17 (2005) 3607-3615
21. Feng Z.Q., Chu X., Huang N.P., Wang T., Wang Y., Shi X., et al. The effect of nanofibrous galactosylated chitosan scaffolds on the formation of rat primary hepatocyte aggregates and the maintenance of liver function. Biomaterials 30 14 (2009 May) 2753-2763
22. Seglen P.O. Preparation of isolated rat liver cells. Methods Cell Biol 13 (1976) 29-83
23. Park I.K., Yang J., Jeong H.J., Bom H.S., Harada I., Akaike T., et al. Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment. Biomaterials 24 13 (2003) 2331-2337
24. Sullivan J.P., Gordon J.E., and Palmer A.F. Simulation of oxygen carrier mediated oxygen transport to C3A hepatoma cells housed within a hollow fiber bioreactor. Biotechnol Bioeng 93 (2006) 306-317
25. McKenzie T.J., Lillegard J.B., and Nyberg S.L. Artificial and bioartificial liver support. Semin Liver Dis 28 2 (2008) 210-217
26. Chan C., Berthiaume F., Nath B.D., Tilles A.W., Toner M., and Yarmush M.L. Hepatic tissue engineering for adjunct and temporary liver support: critical technologies. Liver Transpl 10 11 (2004) 1331-1342
27. Park J.K., and Lee D.H. Bioartificial liver systems: current status and future perspective. J Biosci Bioeng 99 4 (2005) 311-319
28. De Bartolo L., and Bader A. Review of a flat membrane bioreactor as a bioartificial liver. Ann Transplant 6 3 (2001) 40-46
29. Park J., Li Y., Berthiaume F., Toner M., Yarmush M.L., and Tilles A.W. Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates. Biotechnol Bioeng 99 2 (2008) 455-467
30. Chang T.T., and Hughes-Fulford M. Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes. Tissue Eng Part A 15 3 (2009 Mar) 559-567
31. Brophy C.M., Luebke-Wheeler J.L., Amiot B.P., Khan H., Remmel R.P., Rinaldo P., et al. Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function. Hepatology 49 2 (2009 Feb) 578-586
32. Uchino J., Tsuburaya T., Kumagai F., Hase T., Hamada T., Komai T., et al. A hybrid bioartificial liver composed of multiplated hepatocyte monolayers. ASAIO Trans 34 (1988) 972-977
33. De Bartolo L., Jarosch-Von Schweder G., Haverich A., and Bader A. A novel full-scale flat membrane bioreactor utilizing porcine hepatocytes: cell viability and tissue-specific functions. Biotechnol Prog 16 (2000) 102-108
34. Nahmias Y., Berthiaume F., and Yarmush M.L. Integration of technologies for hepatic tissue engineering. Adv Biochem Eng Biotechnol 103 (2007) 309-329
35. Sussman N.L., Gislason G.T., Conlin C.A., and Kelly J.H. The hepatix extracorporeal liver assist device: initial clinical experience. Artif Organs 18 (1994) 390-396
36. Rozga J., Holzman M.D., Ro M.S., Griffin D.W., Neuzil D.F., Giorgio T., et al. Development of a hybrid bioartificial liver. Ann Surg 217 (1993) 502-509
37. Sauer I.M., Obermeyer N., Kardassis D., Theruvath T., and Gerlach J.C. Development of a hybrid liver support system. Ann N Y Acad Sci 944 (2001 Nov) 308-319
38. Sullivan J.P., and Palmer A.F. Targeted oxygen delivery within hepatic hollow fiber bioreactors via supplementation of hemoglobin-based oxygen carriers. Biotechnol Prog 22 (2006) 1374-1387
39. Sullivan J.P., Gordon J.E., Bou-Akl T., Matthew H.W., and Palmer A.F. Enhanced oxygen delivery to primary hepatocytes within a hollow fiber bioreactor facilitated via hemoglobin-based oxygen carriers. Artif Cells Blood Substit Immobil Biotechnol 35 (2007) 585-606
40. Sullivan J.P., Harris D.R., and Palmer A.F. Convection and hemoglobin-based oxygen carrier enhanced oxygen transport in a hepatic hollow fiber bioreactor. Artif Cells Blood Substit Immobil Biotechnol 36 (2008) 386-402
41. Khattak S.F., Chin K.S., Bhatia S.R., and Roberts S.C. Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons. Biotechnol Bioeng 96 (2007) 156-166