Heterozygous NTF4 Mutations Impairing Neurotrophin-4 Signaling in Patients with Primary Open-Angle Glaucoma

American Journal of Human Genetics

Volumn 85, Issue 4, 2009, Pages 447-456

  Pasutto, Francesca ^a   Matsumoto, Tomoya ^b   Mardin, Christian Y ^a   Sticht, Heinrich ^a   Brandstätter, Johann H ^a   Michels Rautenstrauss, Karin ^a   Weisschuh, Nicole ^c   Gramer, Eugen ^d   Ramdas, Wishal D ^e   van Koolwijk, Leonieke M E ^e   Klaver, Caroline C W ^e   Vingerling, Johannes R ^e   Weber, Bernhard H F ^f   Kruse, Friedrich E ^a   Rautenstrauss, Bernd ^a   Barde, Yves Alain ^b   Reis, André ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^d UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN 4; TYROSINE KINASE RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NERVE GROWTH FACTOR;

ADOLESCENT; ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; DISEASE COURSE; EUROPE; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC VARIABILITY; HETEROZYGOSITY; HUMAN; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; MALE; MICROSCOPY; MOLECULAR MODEL; NEUROTROPHIN 4 GENE; NUCLEOTIDE SEQUENCE; OPEN ANGLE GLAUCOMA; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCREENING TEST; GENETICS; HETEROZYGOTE; METABOLISM; MIDDLE AGED; MUTATION; NERVE CELL; PATHOLOGY; SIGNAL TRANSDUCTION;

ADULT; AGED; AGED, 80 AND OVER; DISEASE PROGRESSION; FEMALE; GLAUCOMA, OPEN-ANGLE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; NERVE GROWTH FACTORS; NEURONS; RECEPTOR, TRKB; SIGNAL TRANSDUCTION;

EID: 70350500461     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajhg.2009.08.016     Document Type: Article

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