Expression and localisation of BDNF, NT4 and TrkB in proliferative vitreoretinopathy

Experimental Eye Research

Volumn 86, Issue 5, 2008, Pages 819-827

  Ghazi Nouri, Seyed M S ^a,b   Ellis, James S ^b   Moss, Stephen ^b   Astrid Limb, G ^b   Charteris, David G ^a  

^a MOORFIELDS EYE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

brain derived neurotrophic factor (BDNF); CRALBP; GFAP; neurotrophin 4 (NT4); neurotrophins; proliferative vitreoretinopathy; retinal ganglion cells; retinal M ller cells; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROTROPHIN 4; OPSIN; RETINOID BINDING PROTEIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MUELLER CELL; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETINA GANGLION CELL; RETINA SURGERY; UPREGULATION; VITREORETINOPATHY;

AGED; AGED, 80 AND OVER; BRAIN-DERIVED NEUROTROPHIC FACTOR; EYE PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; RECEPTOR, TRKB; RETINA; RETINAL GANGLION CELLS; ROD OUTER SEGMENTS; VITREORETINOPATHY, PROLIFERATIVE;

EID: 42749090958     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.02.010     Document Type: Article

References (42)

1. Avwenagha O., Bird M.M., Lieberman A.R., Yan Q., and Campbell G. Patterns of expression of brain-derived neurotrophic factor and tyrosine kinase B mRNAs and distribution and ultrastructural localization of their proteins in the visual pathway of the adult rat. Neuroscience 140 (2006) 913-928
2. Biffo S., Offenhauser N., Carter B.D., and Barde Y.A. Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development. Development 121 (1995) 2461-2470
3. Bignami A., and Dahl D. The radial glia of Muller in the rat retina and their response to injury. An immunofluorescence study with antibodies to the glial fibrillary acidic (GFA) protein. Exp. Eye Res. 28 (1979) 63-69
4. Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci. 18 (1995) 223-253
5. Bringmann A., Francke M., Pannicke T., Biedermann B., Faude F., Enzmann V., et al. Human Muller glial cells: altered potassium channel activity in proliferative vitreoretinopathy. Invest. Ophthalmol. Vis. Sci. 40 (1999) 3316-3323
6. Bringmann A., Pannicke T., Moll V., Milenkovic I., Faude F., Enzmann V., et al. Upregulation of P2X(7) receptor currents in Muller glial cells during proliferative vitreoretinopathy. Invest. Ophthalmol. Vis. Sci. 42 (2001) 860-867
7. Bunt-Milam A.H., and Saari J.C. Immunocytochemical localization of two retinoid-binding proteins in vertebrate retina. J. Cell Biol. 97 (1983) 703-712
8. Chao M.V. The p75 neurotrophin receptor. J. Neurobiol. 25 (1994) 1373-1385
9. Cheng A., Coksaygan T., Tang H., Khatri R., Balice-Gordon R.J., Rao M.S., and Mattson M.P. Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism. J. Neurochem. 100 (2007) 1515-3150
10. Cheng L., Sapieha P., Kittlerova P., Hauswirth W.W., and Di Polo A. TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo. J. Neurosci. 22 (2002) 3977-3986
11. Eide F.F., Vining E.R., Eide B.L., Zang K., Wang X.Y., and Reichardt L.F. Naturally occurring truncated trkB receptors have dominant inhibitory effects on brain-derived neurotrophic factor signaling. J. Neurosci. 16 (1996) 3123-3129
12. Erickson P.A., Fisher S.K., Guerin C.J., Anderson D.H., and Kaska D.D. Glial fibrillary acidic protein increases in Muller cells after retinal detachment. Exp. Eye Res. 44 (1987) 37-48
13. Fryer R.H., Kaplan D.R., and Kromer L.F. Truncated trkB receptors on nonneuronal cells inhibit BDNF-induced neurite outgrowth in vitro. Exp. Neurol. 148 (1997) 616-627
14. Gao H., Qiao X., Hefti F., Hollyfield J.G., and Knusel B. Elevated mRNA expression of brain-derived neurotrophic factor in retinal ganglion cell layer after optic nerve injury. Invest. Ophthalmol. Vis. Sci. 38 (1997) 1840-1847
15. Garcia M., Forster V., Hicks D., and Vecino E. In vivo expression of neurotrophins and neurotrophin receptors is conserved in adult porcine retina in vitro. Invest. Ophthalmol. Vis. Sci. 44 (2003) 4532-4541
16. Ghazi-Nouri S.M., Assi A., Limb G.A., Scott R.A., von Bussmann K., Humphrey I., et al. Laser photocoagulation alters the pattern of staining for neurotrophin-4, GFAP, and CD68 in human retina. Br. J. Ophthalmol. 87 (2003) 488-492
17. Hiscott P.S., Grierson I., Trombetta C.J., Rahi A.H., Marshall J., and McLeod D. Retinal and epiretinal glia - an immunohistochemical study. Br. J. Ophthalmol. 68 (1984) 698-707
18. Honjo M., Tanihara H., Kido N., Inatani M., Okazaki K., and Honda Y. Expression of ciliary neurotrophic factor activated by retinal Muller cells in eyes with. Invest. Ophthalmol. Vis. Sci. 41 (2000) 552-560
19. Klein R., Conway D., Parada L.F., and Barbacid M. The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain. Cell 61 (1990) 647-656
20. Kobayashi N.R., Fan D.P., Giehl K.M., Bedard A.M., Wiegand S.J., and Tetzlaff W. BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. J. Neurosci. 17 (1997) 9583-9595
21. Lamballe F., Klein R., and Barbacid M. trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell 66 (1991) 967-979
22. Lambert W., Agarwal R., Howe W., Clark A.F., and Wordinger R.J. Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosa. Invest. Ophthalmol. Vis. Sci. 42 (2001) 2315-2323
23. Liebl D.J., Huang W., Young W., and Parada L.F. Regulation of Trk receptors following contusion of the rat spinal cord. Exp. Neurol. 167 (2001) 15-26
24. Mansour-Robaey S., Clarke D.B., Wang Y.C., Bray G.M., and Aguayo A.J. Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 1632-1636
25. Martin-Zanca D., Barbacid M., and Parada L.F. Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes Dev. 4 (1990) 683-694
26. Middlemas D.S., Lindberg R.A., and Hunter T. trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. Mol. Cell Biol. 11 (1991) 143-153
27. Milenkovic I., Weick M., Wiedemann P., Reichenbach A., and Bringmann A. P2Y receptor-mediated stimulation of Muller glial cell DNA synthesis: dependence on EGF and PDGF receptor transactivation. Invest. Ophthalmol. Vis. Sci. 44 (2003) 1211-1220
28. Morino I., Hiscott P., McKechnie N., and Grierson I. Variation in epiretinal membrane components with clinical duration of the proliferative tissue. Br. J. Ophthalmol. 74 (1990) 393-399
29. Mu X., and Klein W.H. A gene regulatory hierarchy for retinal ganglion cell specification and differentiation. Semin. Cell Dev. Biol. 15 (2004) 115-123
30. Okada M., Matsumura M., Ogino N., and Honda Y. Müller cells in detached human retina express glial fibrillary acidic protein and vimentin. Graefes Arch. Clin. ExpOphthalmol. 228 (1990) 467-474
31. Oku H., Ikeda T., Honma Y., Sotozono C., Nishida K., Nakamura Y., et al. Gene expression of neurotrophins and their high-affinity Trk receptors in cultured human Muller cells. Ophthalmic Res. 34 (2002) 38-42
32. Osborne N.N., Block F., and Sontag K.H. Reduction of ocular blood flow results in glial fibrillary acidic protein (GFAP) expression in rat retinal Muller cells. Vis. Neurosci. 7 (1991) 637-639
33. Reichardt L.F., and Farinas I. Neurotrophic factors and their receptors: roles in neuronal development and function. In: Cowan W.M., Zipursky L., and Jelles T.M. (Eds). Molecular and Cellular Approaches to Neural Development (1997), Oxford University Press, New York 220-263
34. Rodrigues M.M., Newsome D.A., and Machemer R. Further characterization of epiretinal membranes in human massive periretinal proliferation. Curr. Eye Res. 1 (1981) 311-315
35. Sethi C.S., Lewis G.P., Fisher S.K., Leitner W.P., Mann D.L., Luthert P.J., and Charteris D.G. Glial remodeling and neural plasticity in human retinal detachment with proliferative vitreoretinopathy. Invest. Ophthalmol. Vis. Sci. 46 (2005) 329-342
36. Turner B.A., Sparrow J., Cai B., Monroe J., Mikawa T., and Hempstead B.L. TrkB/BDNF signaling regulates photoreceptor progenitor cell fate decisions. Dev. Biol. 299 (2006) 455-465
37. Tsoulfas P., Soppet D., Escandon E., Tessarollo L., Mendoza-Ramirez J.L., Rosenthal A., et al. The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells. Neuron 10 (1993) 975-990
38. Valenzuela D.M., Maisonpierre P.C., Glass D.J., Rojas E., Nunez L., Kong Y., et al. Alternative forms of rat TrkC with different functional capabilities. Neuron 10 (1993) 963-974
39. Van Horn D.L., Aaberg T.M., Machemer R., and Fenzl R. Glial cell proliferation in human retinal detachment with massive periretinal proliferation. Am. J. Ophthalmol. 84 (1977) 383-393
40. Venero J.L., Knusel B., Beck K.D., and Hefti F. Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administration. Neuroscience 59 (1994) 797-815
41. Wahlin K.J., Campochiaro P.A., Zack D.J., and Adler R. Neurotrophic factors cause activation of intracellular signaling pathways in Muller cells and other cells of the inner retina, but not photoreceptors. Invest. Ophthalmol. Vis. Sci. 41 (2000) 927-936
42. Wordinger R.J., Lambert W., Agarwal R., Talati M., and Clark A.F. Human trabecular meshwork cells secrete neurotrophins and express neurotrophin receptors (Trk). Invest. Ophthalmol. Vis. Sci. 41 (2000) 3833-3841