메뉴 건너뛰기




Volumn 29, Issue 1, 2009, Pages 108-118

Association between polymorphism in uncoupling proteins and type 2 diabetes in a northwestern colombian population;Asociación de variantes en genes de las proteínas desacoplantes con diabetes mellitus tipo 2 en una población del nordeste colombiano

Author keywords

Diabetes mellitus genetics; Genotype; Haplotypes; Insulin resistance; Obesity; Polymorphism

Indexed keywords

ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; MITOCHONDRIAL UNCOUPLING PROTEIN 3;

EID: 70350464781     PISSN: 01204157     EISSN: None     Source Type: Journal    
DOI: 10.7705/biomedica.v29i1.46     Document Type: Article
Times cited : (13)

References (55)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414:782-7.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 2
    • 1842526874 scopus 로고    scopus 로고
    • Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification
    • McCarthy MI. Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification. Hum Mol Genet. 2004;13:33-41.
    • (2004) Hum Mol Genet , vol.13 , pp. 33-41
    • McCarthy, M.I.1
  • 3
    • 19944363176 scopus 로고    scopus 로고
    • Genes and type 2 diabetes mellitus
    • Tusie Luna MT. Genes and type 2 diabetes mellitus. Arch Med Res. 2005;36:210-22.
    • (2005) Arch Med Res , vol.36 , pp. 210-222
    • Tusie Luna, M.T.1
  • 4
    • 11844255438 scopus 로고    scopus 로고
    • Evolution of mitochondrial uncoupling proteins: novel invertebrate UCP homologues suggest early evolutionary divergence of the UCP family
    • Sokolova IM, Sokolov EP. Evolution of mitochondrial uncoupling proteins: novel invertebrate UCP homologues suggest early evolutionary divergence of the UCP family. FEBS Lett. 2005;579:313-7.
    • (2005) FEBS Lett , vol.579 , pp. 313-317
    • Sokolova, I.M.1    Sokolov, E.P.2
  • 5
    • 38849084502 scopus 로고    scopus 로고
    • UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells
    • Li Y, Maedler K, Shu L, Haataja L. UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells. PLoS ONE. 2008;3:e1397.
    • (2008) PLoS ONE , vol.3
    • Li, Y.1    Maedler, K.2    Shu, L.3    Haataja, L.4
  • 6
    • 0037253404 scopus 로고    scopus 로고
    • The 'novel' 'uncoupling' proteins UCP2 and UCP3: what do they really do? Pros and cons for suggested functions
    • Nedergaard J, Cannon B. The 'novel' 'uncoupling' proteins UCP2 and UCP3: what do they really do? Pros and cons for suggested functions. Exp Physiol. 2003;88:65-84.
    • (2003) Exp Physiol , vol.88 , pp. 65-84
    • Nedergaard, J.1    Cannon, B.2
  • 9
    • 34247246709 scopus 로고    scopus 로고
    • The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study
    • Sale MM, Hsu FC, Palmer ND, Gordon CJ, Keene KL, Borgerink HM, et al. The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study. BMC Endocr Disord. 2007;7:1.
    • (2007) BMC Endocr Disord , vol.7 , pp. 1
    • Sale, M.M.1    Hsu, F.C.2    Palmer, N.D.3    Gordon, C.J.4    Keene, K.L.5    Borgerink, H.M.6
  • 11
    • 42449114459 scopus 로고    scopus 로고
    • Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study
    • Hsu YH, Niu T, Song Y, Tinker L, Kuller LH, Liu S. Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study. Diabetes. 2008;57:1101-7.
    • (2008) Diabetes , vol.57 , pp. 1101-1107
    • Hsu, Y.H.1    Niu, T.2    Song, Y.3    Tinker, L.4    Kuller, L.H.5    Liu, S.6
  • 12
    • 33745312588 scopus 로고    scopus 로고
    • Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men
    • Gable DR, Stephens JW, Cooper JA, Miller GJ, Humphries SE. Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men. Diabetes. 2006;55:1504-11.
    • (2006) Diabetes , vol.55 , pp. 1504-1511
    • Gable, D.R.1    Stephens, J.W.2    Cooper, J.A.3    Miller, G.J.4    Humphries, S.E.5
  • 13
    • 23744516219 scopus 로고    scopus 로고
    • The effects of UCP-1 polymorphisms on obesity phenotypes among Korean female subjects
    • Shin HD, Kim KS, Cha MH, Yoon Y. The effects of UCP-1 polymorphisms on obesity phenotypes among Korean female subjects. Biochem Biophys Res Commun. 2005;335:624-30.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 624-630
    • Shin, H.D.1    Kim, K.S.2    Cha, M.H.3    Yoon, Y.4
  • 14
    • 70349566593 scopus 로고
    • Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?
    • Neel JV. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet. 1962;14:353-62.
    • (1962) Am J Hum Genet , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 15
    • 0022896508 scopus 로고
    • Relationship of prevalence of non-insulin-dependent diabetes mellitus to Amerindian admixture in the Mexican Americans of San Antonio
    • Chakraborty R, Ferrell RE, Stern MP, Haffner SM, Hazuda HP, Rosenthal M. Relationship of prevalence of non-insulin-dependent diabetes mellitus to Amerindian admixture in the Mexican Americans of San Antonio, Texas. Genet Epidemiol. 1986;3:435-54.
    • (1986) Texas. Genet Epidemiol , vol.3 , pp. 435-454
    • Chakraborty, R.1    Ferrell, R.E.2    Stern, M.P.3    Haffner, S.M.4    Hazuda, H.P.5    Rosenthal, M.6
  • 16
    • 0031897103 scopus 로고    scopus 로고
    • Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994
    • Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care. 1998;21:518-24.
    • (1998) Diabetes Care , vol.21 , pp. 518-524
    • Harris, M.I.1    Flegal, K.M.2    Cowie, C.C.3    Eberhardt, M.S.4    Goldstein, D.E.5    Little, R.R.6
  • 17
    • 0033925030 scopus 로고    scopus 로고
    • Individual estimates of European genetic admixture associated with lower body-mass index, plasma glucose, and prevalence of type 2 diabetes in Pima Indians
    • Williams RC, Long JC, Hanson RL, Sievers ML, Knowler WC. Individual estimates of European genetic admixture associated with lower body-mass index, plasma glucose, and prevalence of type 2 diabetes in Pima Indians. Am J Hum Genet. 2000;66:527-38.
    • (2000) Am J Hum Genet , vol.66 , pp. 527-538
    • Williams, R.C.1    Long, J.C.2    Hanson, R.L.3    Sievers, M.L.4    Knowler, W.C.5
  • 19
    • 33646561827 scopus 로고    scopus 로고
    • Admixture dynamics in Hispanics: a shift in the nuclear genetic ancestry of a South American population isolate
    • Bedoya G, Montoya P, García J, Soto I, Bourgeois S, Carvajal L, et al. Admixture dynamics in Hispanics: a shift in the nuclear genetic ancestry of a South American population isolate. Proc Natl Acad Sci USA. 2006;103:7234-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7234-7239
    • Bedoya, G.1    Montoya, P.2    García, J.3    Soto, I.4    Bourgeois, S.5    Carvajal, L.6
  • 20
    • 0344211847 scopus 로고    scopus 로고
    • Using genetic admixture to explain racial differences in insulin-related phenotypes
    • Gower BA, Fernández JR, Beasley TM, Shriver MD, Goran MI. Using genetic admixture to explain racial differences in insulin-related phenotypes. Diabetes. 2003;52:1047-51.
    • (2003) Diabetes , vol.52 , pp. 1047-1051
    • Gower, B.A.1    Fernández, J.R.2    Beasley, T.M.3    Shriver, M.D.4    Goran, M.I.5
  • 22
    • 17144403675 scopus 로고    scopus 로고
    • Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley
    • Parra EJ, Hoggart CJ, Bonilla C, Dios S, Norris JM, Marshall JA, et al. Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado. J Med Genet. 2004;41:e116.
    • (2004) Colorado. J Med Genet. , vol.41
    • Parra, E.J.1    Hoggart, C.J.2    Bonilla, C.3    Dios, S.4    Norris, J.M.5    Marshall, J.A.6
  • 26
    • 77649314332 scopus 로고
    • GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism
    • Raymond M, Rousset F. GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Hered. 1995;86.
    • (1995) J Hered , pp. 86
    • Raymond, M.1    Rousset, F.2
  • 28
    • 0033930943 scopus 로고    scopus 로고
    • Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations
    • McKeigue PM, Carpenter JR, Parra EJ, Shriver MD. Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations. Ann Hum Genet. 2000;64:171-86.
    • (2000) Ann Hum Genet , vol.64 , pp. 171-186
    • McKeigue, P.M.1    Carpenter, J.R.2    Parra, E.J.3    Shriver, M.D.4
  • 29
    • 0346101854 scopus 로고    scopus 로고
    • The -3826 A-->G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys
    • Nagai N, Sakane N, Ueno LM, Hamada T, Moritani T. The -3826 A-->G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys. J Clin Endocrinol Metab. 2003;88:5661-7.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5661-5667
    • Nagai, N.1    Sakane, N.2    Ueno, L.M.3    Hamada, T.4    Moritani, T.5
  • 31
    • 0033999008 scopus 로고    scopus 로고
    • Association of -3826 G variant in uncoupling protein-1 with increased BMI in overweight Australian women
    • Heilbronn LK, Kind KL, Pancewicz E, Morris AM, Noakes M, Clifton PM. Association of -3826 G variant in uncoupling protein-1 with increased BMI in overweight Australian women. Diabetologia. 2000;43:242-4.
    • (2000) Diabetologia , vol.43 , pp. 242-244
    • Heilbronn, L.K.1    Kind, K.L.2    Pancewicz, E.3    Morris, A.M.4    Noakes, M.5    Clifton, P.M.6
  • 32
    • 20444498707 scopus 로고    scopus 로고
    • The finding of new genetic polymorphism of UCP-1 A-1766G and its effects on body fat accumulation
    • Kim KS, Cho DY, Kim YJ, Choi SM, Kim JY, Shin SU, et al. The finding of new genetic polymorphism of UCP-1 A-1766G and its effects on body fat accumulation. Biochim Biophys Acta. 2005;1741:149-55.
    • (2005) Biochim Biophys Acta , vol.1741 , pp. 149-155
    • Kim, K.S.1    Cho, D.Y.2    Kim, Y.J.3    Choi, S.M.4    Kim, J.Y.5    Shin, S.U.6
  • 33
    • 4844229786 scopus 로고    scopus 로고
    • Common variants in beta2- and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish Diabetes Prevention Study
    • Salopuro T, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, et al. Common variants in beta2- and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish Diabetes Prevention Study. Clin Genet. 2004;66:365-7.
    • (2004) Clin Genet , vol.66 , pp. 365-367
    • Salopuro, T.1    Lindstrom, J.2    Eriksson, J.G.3    Valle, T.T.4    Hamalainen, H.5    Ilanne-Parikka, P.6
  • 34
    • 0031957513 scopus 로고    scopus 로고
    • Uncoupling protein-1 mRNA expression in obese human subjects: the role of sequence variations at the uncoupling protein-1 gene locus
    • Esterbauer H, Oberkofler H, Liu YM, Breban D, Hell E, Krempler F, et al. Uncoupling protein-1 mRNA expression in obese human subjects: the role of sequence variations at the uncoupling protein-1 gene locus. J Lipid Res. 1998;39:834-44.
    • (1998) J Lipid Res , vol.39 , pp. 834-844
    • Esterbauer, H.1    Oberkofler, H.2    Liu, Y.M.3    Breban, D.4    Hell, E.5    Krempler, F.6
  • 35
    • 0036588521 scopus 로고    scopus 로고
    • Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells
    • Nakazaki M, Kakei M, Ishihara H, Koriyama N, Hashiguchi H, Aso K, et al. Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells. J Physiol. 2002;540:781-9.
    • (2002) J Physiol , vol.540 , pp. 781-789
    • Nakazaki, M.1    Kakei, M.2    Ishihara, H.3    Koriyama, N.4    Hashiguchi, H.5    Aso, K.6
  • 36
    • 0036078412 scopus 로고    scopus 로고
    • Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice
    • Bernal-Mizrachi C, Weng S, Li B, Nolte LA, Feng C, Coleman T, et al. Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice. Arterioscler Thromb Vasc Biol. 2002;22:961-8.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 961-968
    • Bernal-Mizrachi, C.1    Weng, S.2    Li, B.3    Nolte, L.A.4    Feng, C.5    Coleman, T.6
  • 37
    • 3242734890 scopus 로고    scopus 로고
    • Starvation-sensitive UCP 3 protein expression in thymus and spleen mitochondria
    • Carroll AM, Porter RK. Starvation-sensitive UCP 3 protein expression in thymus and spleen mitochondria. Biochim Biophys Acta. 2004;1700:145-50.
    • (2004) Biochim Biophys Acta , vol.1700 , pp. 145-150
    • Carroll, A.M.1    Porter, R.K.2
  • 38
    • 3042730677 scopus 로고    scopus 로고
    • Quantitative rt-PCR analysis of uncoupling protein isoforms in mouse brain cortex: methodological optimization and comparison of expression with brown adipose tissue and skeletal muscle
    • Lengacher S, Magistretti PJ, Pellerin L. Quantitative rt-PCR analysis of uncoupling protein isoforms in mouse brain cortex: methodological optimization and comparison of expression with brown adipose tissue and skeletal muscle. J Cereb Blood Flow Metab. 2004;24:780-8.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 780-788
    • Lengacher, S.1    Magistretti, P.J.2    Pellerin, L.3
  • 40
    • 42749100308 scopus 로고    scopus 로고
    • PPARs in the control of uncoupling proteins gene expression
    • Villarroya F, Iglesias R, Giralt M. PPARs in the control of uncoupling proteins gene expression. PPAR Res. 2007;2007:74364.
    • (2007) PPAR Res , vol.2007 , pp. 74364
    • Villarroya, F.1    Iglesias, R.2    Giralt, M.3
  • 41
    • 0033735893 scopus 로고    scopus 로고
    • An uncoupling protein 3 gene polymorphism associated with a lower risk of developing type II diabetes and with atherogenic lipid profile in a French cohort
    • Meirhaeghe A, Amouyel P, Helbecque N, Cottel D, Otabe S, Froguel P, et al. An uncoupling protein 3 gene polymorphism associated with a lower risk of developing type II diabetes and with atherogenic lipid profile in a French cohort. Diabetologia. 2000;43:1424-8.
    • (2000) Diabetologia , vol.43 , pp. 1424-1428
    • Meirhaeghe, A.1    Amouyel, P.2    Helbecque, N.3    Cottel, D.4    Otabe, S.5    Froguel, P.6
  • 42
    • 1842427206 scopus 로고    scopus 로고
    • Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females
    • Damcott CM, Feingold E, Moffett SP, Barmada MM, Marshall JA, Hamman RF, et al. Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females. Metabolism. 2004;53:458-64.
    • (2004) Metabolism , vol.53 , pp. 458-464
    • Damcott, C.M.1    Feingold, E.2    Moffett, S.P.3    Barmada, M.M.4    Marshall, J.A.5    Hamman, R.F.6
  • 43
    • 0033406189 scopus 로고    scopus 로고
    • A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians
    • Schrauwen P, Xia J, Walder K, Snitker S, Ravussin E. A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians. Int J Obes Relat Metab Disord. 1999;23:1242-5.
    • (1999) Int J Obes Relat Metab Disord , vol.23 , pp. 1242-1245
    • Schrauwen, P.1    Xia, J.2    Walder, K.3    Snitker, S.4    Ravussin, E.5
  • 45
    • 0006877856 scopus 로고    scopus 로고
    • Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean
    • Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, et al. Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean. Nature. 2000;406:415-8.
    • (2000) Nature , vol.406 , pp. 415-418
    • Clapham, J.C.1    Arch, J.R.2    Chapman, H.3    Haynes, A.4    Lister, C.5    Moore, G.B.6
  • 46
    • 34447130778 scopus 로고    scopus 로고
    • Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance
    • Choi CS, Fillmore JJ, Kim JK, Liu ZX, Kim S, Collier EF, et al. Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. J Clin Invest. 2007;117:1995-2003.
    • (2007) J Clin Invest , vol.117 , pp. 1995-2003
    • Choi, C.S.1    Fillmore, J.J.2    Kim, J.K.3    Liu, Z.X.4    Kim, S.5    Collier, E.F.6
  • 47
    • 0034972150 scopus 로고    scopus 로고
    • A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
    • Esterbauer H, Schneitler C, Oberkofler H, Ebenbichler C, Paulweber B, Sandhofer F, et al. A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat Genet. 2001;28:178-83.
    • (2001) Nat Genet , vol.28 , pp. 178-183
    • Esterbauer, H.1    Schneitler, C.2    Oberkofler, H.3    Ebenbichler, C.4    Paulweber, B.5    Sandhofer, F.6
  • 50
    • 2242479140 scopus 로고    scopus 로고
    • La política farmacéutica nacional en Colombia y la reforma de la seguridad social: acceso y uso racional de medicamentos
    • Mejía S, Vélez A, Buriticá O, Arango M, Del-Río J. La política farmacéutica nacional en Colombia y la reforma de la seguridad social: acceso y uso racional de medicamentos. Cad Saude Publica. 2002;18:1025-39.
    • (2002) Cad Saude Publica , vol.18 , pp. 1025-1039
    • Mejía, S.1    Vélez, A.2    Buriticá, O.3    Arango, M.4    Del-Río, J.5
  • 51
    • 53149093601 scopus 로고    scopus 로고
    • Genes, environment, and interactions in prevention of type 2 diabetes: a focus on physical activity and lifestyle changes
    • Qi L, Hu FB, Hu G. Genes, environment, and interactions in prevention of type 2 diabetes: a focus on physical activity and lifestyle changes. Curr Mol Med. 2008;8:519-32.
    • (2008) Curr Mol Med , vol.8 , pp. 519-532
    • Qi, L.1    Hu, F.B.2    Hu, G.3
  • 52
    • 0028917432 scopus 로고
    • Weight gain as a risk factor for clinical diabetes mellitus in women
    • Colditz GA, Willett WC, Rotnitzky A, Manson JE. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med. 1995;122:481-6.
    • (1995) Ann Intern Med , vol.122 , pp. 481-486
    • Colditz, G.A.1    Willett, W.C.2    Rotnitzky, A.3    Manson, J.E.4
  • 53
    • 19944390213 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus
    • Leahy JL. Pathogenesis of type 2 diabetes mellitus. Arch Med Res. 2005;36:197-209.
    • (2005) Arch Med Res , vol.36 , pp. 197-209
    • Leahy, J.L.1
  • 55
    • 42449098483 scopus 로고    scopus 로고
    • The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men
    • Cheurfa N, Dubois-Laforgue D, Ferrarezi DA, Reis AF, Brenner GM, Bouche C, et al. The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men. Diabetes. 2008;57:1063-8.
    • (2008) Diabetes , vol.57 , pp. 1063-1068
    • Cheurfa, N.1    Dubois-Laforgue, D.2    Ferrarezi, D.A.3    Reis, A.F.4    Brenner, G.M.5    Bouche, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.