-
1
-
-
0023851885
-
Reduced rate of energy expenditure as a risk factor for body-weight gain
-
Ravussin, E., S. Lillioja, W. C. Knowler, L. Christin, D. Freymond, W. G. Abbott, V. Boyce, B. V. Howard, and C. Bogardus. 1988. Reduced rate of energy expenditure as a risk factor for body-weight gain. N. Engl. J. Med. 318: 467-472.
-
(1988)
N. Engl. J. Med.
, vol.318
, pp. 467-472
-
-
Ravussin, E.1
Lillioja, S.2
Knowler, W.C.3
Christin, L.4
Freymond, D.5
Abbott, W.G.6
Boyce, V.7
Howard, B.V.8
Bogardus, C.9
-
2
-
-
0025302098
-
Metabolic rate and physical development in children at risk of obesity
-
Griffiths, M., P. R. Pazne, A. J. Stunkard, J. P. Rivers, and M. Cox. 1990. Metabolic rate and physical development in children at risk of obesity. Lancet. 336: 76-78.
-
(1990)
Lancet
, vol.336
, pp. 76-78
-
-
Griffiths, M.1
Pazne, P.R.2
Stunkard, A.J.3
Rivers, J.P.4
Cox, M.5
-
3
-
-
0022592847
-
Familial dependence of the resting metabolic rate
-
Bogardus, C., S. Lillioja, E. Ravussin, W. Abbott, J. K. Zawadzki, A. Young, W. C. Knowler, R. Jacobowitz, and P. P. Moll. 1986. Familial dependence of the resting metabolic rate. N. Engl. J. Med. 315: 96-100.
-
(1986)
N. Engl. J. Med.
, vol.315
, pp. 96-100
-
-
Bogardus, C.1
Lillioja, S.2
Ravussin, E.3
Abbott, W.4
Zawadzki, J.K.5
Young, A.6
Knowler, W.C.7
Jacobowitz, R.8
Moll, P.P.9
-
4
-
-
0024503903
-
Genetic effect in resting and exercise metabolic rates
-
Bouchard, C., A. Tremblay, A. Nadeau, J. P. Despres, G. Theriault, M. R. Boulay, G. Lortie, C. Leblanc, and G. Fournier. 1989. Genetic effect in resting and exercise metabolic rates. Metabolism. 38: 364-370.
-
(1989)
Metabolism
, vol.38
, pp. 364-370
-
-
Bouchard, C.1
Tremblay, A.2
Nadeau, A.3
Despres, J.P.4
Theriault, G.5
Boulay, M.R.6
Lortie, G.7
Leblanc, C.8
Fournier, G.9
-
5
-
-
0024831575
-
Brown adipose tissue thermogenesis and obesity
-
Himms-Hagen, J. 1989. Brown adipose tissue thermogenesis and obesity. Prog. Lipid Res. 28: 67-115.
-
(1989)
Prog. Lipid Res.
, vol.28
, pp. 67-115
-
-
Himms-Hagen, J.1
-
6
-
-
0021322138
-
Thermogenic mechanisms in brown fat
-
Nicholls, D. G., and R. M. Locke. 1984. Thermogenic mechanisms in brown fat. Physiol. Rev. 64: 1-64.
-
(1984)
Physiol. Rev.
, vol.64
, pp. 1-64
-
-
Nicholls, D.G.1
Locke, R.M.2
-
7
-
-
0025861442
-
The uncoupling protein UCP: A membraneous mitochondrial ion carrier exclusively expressed in brown adipose tissue
-
Klaus, S., L. Casteilla, F. Bouillaud, and D. Ricquier. 1991. The uncoupling protein UCP: a membraneous mitochondrial ion carrier exclusively expressed in brown adipose tissue. Int. J. Biochem. 23: 791-801.
-
(1991)
Int. J. Biochem.
, vol.23
, pp. 791-801
-
-
Klaus, S.1
Casteilla, L.2
Bouillaud, F.3
Ricquier, D.4
-
8
-
-
0030039607
-
On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein
-
Garlid, K. D., D. E. Orosz, M. Modriansky, S. Vassanelli, and P. J. Jezek. 1996. On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein. J. Biol. Chem. 271: 2615-2620.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2615-2620
-
-
Garlid, K.D.1
Orosz, D.E.2
Modriansky, M.3
Vassanelli, S.4
Jezek, P.J.5
-
9
-
-
0031019249
-
Uncoupling protein-2: A novel gene linked to obesity and hyperin-sulinemia
-
Fleury, C., M. Neverova, S. Collins, S. Raimbault, O. Champigny, C. Levy-Meyrueis, F. Bouillaud, M. F. Seldin, R.S. Surwit, D. Riquier, and C. H. Warden. 1997. Uncoupling protein-2: a novel gene linked to obesity and hyperin-sulinemia. Nat. Genet. 15: 269-272.
-
(1997)
Nat. Genet.
, vol.15
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levy-Meyrueis, C.6
Bouillaud, F.7
Seldin, M.F.8
Surwit, R.S.9
Riquier, D.10
Warden, C.H.11
-
10
-
-
15144356206
-
Cloning and characterization of an uncoupling protein homolog. A potential molecular mediator of human thermogenesis
-
Gimeno, R. E., M. Dembski, X. Weng, N. Deng, A. W. Shyjan, C. J. Gimeno, F. Iris, S. J. Ellis, E. A. Woolf, and L. A. Tartaglia. 1997. Cloning and characterization of an uncoupling protein homolog. A potential molecular mediator of human thermogenesis. Diabetes. 46: 900-906.
-
(1997)
Diabetes
, vol.46
, pp. 900-906
-
-
Gimeno, R.E.1
Dembski, M.2
Weng, X.3
Deng, N.4
Shyjan, A.W.5
Gimeno, C.J.6
Iris, F.7
Ellis, S.J.8
Woolf, E.A.9
Tartaglia, L.A.10
-
11
-
-
0030988140
-
Uncoupling protein-3: A new member of the mitochondrial carrier family with tissue-specific expression
-
Boss, O., S. Samec, A. Paoloni-Giacobino, C. Rossier, A. Dulloo, J. Seydoux, P. Muzzin, and J-P. Giacobino. 1997. Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408: 39-42.
-
(1997)
FEBS Lett.
, vol.408
, pp. 39-42
-
-
Boss, O.1
Samec, S.2
Paoloni-Giacobino, A.3
Rossier, C.4
Dulloo, A.5
Seydoux, J.6
Muzzin, P.7
Giacobino, J.-P.8
-
12
-
-
0031560941
-
UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
-
Vidal-Puig, A., G. Solanes, D. Grujic, J. S. Flier, and B. B. Lowell. 1997. UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem. Biophys. Res. Commun. 235: 79-82.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.235
, pp. 79-82
-
-
Vidal-Puig, A.1
Solanes, G.2
Grujic, D.3
Flier, J.S.4
Lowell, B.B.5
-
13
-
-
0024997854
-
α- and β-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture
-
Rehnmark, S., M. Nechad, D. Herron, B. Cannon, and J. Nedergaard. 1990. α- and β-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture. J. Biol. Chem. 265: 16464-16471.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 16464-16471
-
-
Rehnmark, S.1
Nechad, M.2
Herron, D.3
Cannon, B.4
Nedergaard, J.5
-
14
-
-
0019814864
-
Metabolic relationships between lipolysis and respiration in rat brown adipocytes. The role of long chain fatty acids as regulators of mitochondrial respiration and feedback inhibitors of lipolysis
-
Bukowiecki, L. J., N. Follea, J. Lupien, and A. J. Paradis. 1981. Metabolic relationships between lipolysis and respiration in rat brown adipocytes. The role of long chain fatty acids as regulators of mitochondrial respiration and feedback inhibitors of lipolysis. J. Biol. Chem. 256: 12840-12848.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 12840-12848
-
-
Bukowiecki, L.J.1
Follea, N.2
Lupien, J.3
Paradis, A.J.4
-
15
-
-
0028838836
-
3-adrenergic receptor gene
-
3-adrenergic receptor gene. J. Biol. Chem. 270: 29483-29492.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29483-29492
-
-
Susulic, V.S.1
Frederich, R.C.2
Lawitts, J.3
Tozzo, E.4
Kahn, B.B.5
Harper, M.-E.6
Himms-Hagen, J.7
Flier, J.S.8
Lowell, B.B.9
-
16
-
-
0029887455
-
3-adrenergic agonist
-
3-adrenergic agonist. J. Clin. Invest. 97: 2898-2904.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2898-2904
-
-
Nagase, I.1
Yoshida, T.2
Kumamoto, K.3
Umekawa, T.4
Sakane, N.5
Nikami, H.6
Kawada, T.7
Saito, M.8
-
17
-
-
0029084088
-
3-adrenergic-receptor gene
-
3-adrenergic-receptor gene. N. Engl. J. Med. 333: 348-351.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 348-351
-
-
Walston, J.1
Silver, K.2
Bogardus, C.3
Knowler, W.C.4
Celi, F.S.5
Austin, S.6
Manning, B.7
Strosberg, A.D.8
Stern, M.P.9
Raben, N.10
Sorkin, J.D.11
Roth, J.12
Shuldiner, A.R.13
-
19
-
-
0028978910
-
3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity
-
3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N. Engl. J. Med. 333: 352-354.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 352-354
-
-
Clement, K.1
Vaisse, C.2
Manning, B.St.J.3
Basdevant, A.4
Guy-Grand, B.5
Ruiz, J.6
Silver, K.D.7
Shuldiner, A.R.8
Froguel, P.9
Strosberg, A.D.10
-
20
-
-
0029843407
-
Additive effect of A→G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity
-
Clement, K., J. Ruiz, A. M. Cassard-Doulcier, F. Bouillaud, D. Ricquier, A. Basdevant, B. Guygrand, P. Froguel. 1996. Additive effect of A→G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity. Int. J. Obes. Relat. Metab. Disord. 20: 1062-1066.
-
(1996)
Int. J. Obes. Relat. Metab. Disord.
, vol.20
, pp. 1062-1066
-
-
Clement, K.1
Ruiz, J.2
Cassard-Doulcier, A.M.3
Bouillaud, F.4
Ricquier, D.5
Basdevant, A.6
Guygrand, B.7
Froguel, P.8
-
21
-
-
0029800686
-
Polymorphism of uncoupling protein (UCP) and beta 3-adrenoreceptor gene in obese people submitted to a low calorie diet
-
Fumeron, F., I. Durackbown, D. Betoulle, A. M. Cassard-Doulcier, S. Tuzet, F. Bouillaud, J. C. Melchior, D. Ricquier, and M. Apfelbaum. 1996. Polymorphism of uncoupling protein (UCP) and beta 3-adrenoreceptor gene in obese people submitted to a low calorie diet. Int. J. Obes. Relat. Metab. Disord. 20: 1051-1054.
-
(1996)
Int. J. Obes. Relat. Metab. Disord.
, vol.20
, pp. 1051-1054
-
-
Fumeron, F.1
Durackbown, I.2
Betoulle, D.3
Cassard-Doulcier, A.M.4
Tuzet, S.5
Bouillaud, F.6
Melchior, J.C.7
Ricquier, D.8
Apfelbaum, M.9
-
22
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, N., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, N.1
Sacchi, N.2
-
23
-
-
0030717887
-
Uncoupling protein gene: Quantification of expression levels in adipose tissues of obese and non-obese humans
-
Oberkofler, H., G. Dallinger, Y-M. Liu, E. Hell, F. Krempler, and W. Patsch. 1997. Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans. J. Lipid Res. 38: 2125-2133.
-
(1997)
J. Lipid Res.
, vol.38
, pp. 2125-2133
-
-
Oberkofler, H.1
Dallinger, G.2
Liu, Y.-M.3
Hell, E.4
Krempler, F.5
Patsch, W.6
-
24
-
-
0025326334
-
Gene splicing by overlap extension: Tailor-made genes using the polymerase chain reaction
-
Horton, R. M., Z. Cai, S. N. Ho, and L. R. Pease. 1990. Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. Bio-Techniques. 8: 528-535.
-
(1990)
Bio-Techniques
, vol.8
, pp. 528-535
-
-
Horton, R.M.1
Cai, Z.2
Ho, S.N.3
Pease, L.R.4
-
25
-
-
0029928645
-
The Bcl I polymorphism of the human uncoupling protein (ucp) gene is due to a point mutation in the 5′ region
-
Cassard-Doulcier, A. M., F. Bouillaud, M. Chagnon, C. Gelly, F. T. Dionne, J. M. Oppert, C. Bouchard, Y. Chagnon, and D. Ricquier. 1996. The Bcl I polymorphism of the human uncoupling protein (ucp) gene is due to a point mutation in the 5′ region. Int. J. Obes. Relat. Metab. Disord. 20: 278-279.
-
(1996)
Int. J. Obes. Relat. Metab. Disord.
, vol.20
, pp. 278-279
-
-
Cassard-Doulcier, A.M.1
Bouillaud, F.2
Chagnon, M.3
Gelly, C.4
Dionne, F.T.5
Oppert, J.M.6
Bouchard, C.7
Chagnon, Y.8
Ricquier, D.9
-
26
-
-
0023430504
-
Gametic disequilibrium measures: Proceed with caution
-
Hedrick, P. W. 1987. Gametic disequilibrium measures: proceed with caution. Genetics. 117: 331-341.
-
(1987)
Genetics
, vol.117
, pp. 331-341
-
-
Hedrick, P.W.1
-
27
-
-
0016319012
-
Estimation of linkage disequilibrium in randomly mating populations
-
Hill, W. G. 1974. Estimation of linkage disequilibrium in randomly mating populations. Heredity. 33: 229-239.
-
(1974)
Heredity
, vol.33
, pp. 229-239
-
-
Hill, W.G.1
-
28
-
-
0004149270
-
-
Irwin, Inc., Chicago, IL
-
Neter, J., M. H. Kutner, C. J. Nachtsheim, and W. Wasserman. 1996. Applied Linear Statistical Methods. Irwin, Inc., Chicago, IL.
-
(1996)
Applied Linear Statistical Methods
-
-
Neter, J.1
Kutner, M.H.2
Nachtsheim, C.J.3
Wasserman, W.4
-
30
-
-
0028136536
-
DNA polymorphism in the uncoupling protein (UCP) gene and human body fat
-
Oppert, J-M., M-C. Vohl, M. Chagnon, F. T. Dionne, A-M. Cassard-Doulcier, D. Riquier, L. Perusse, and C. Bouchard. 1994. DNA polymorphism in the uncoupling protein (UCP) gene and human body fat. Int. J. Obes. Relat. Metab. Disord. 18: 526-531.
-
(1994)
Int. J. Obes. Relat. Metab. Disord.
, vol.18
, pp. 526-531
-
-
Oppert, J.-M.1
Vohl, M.-C.2
Chagnon, M.3
Dionne, F.T.4
Cassard-Doulcier, A.-M.5
Riquier, D.6
Perusse, L.7
Bouchard, C.8
-
31
-
-
0027392074
-
Tissue distribution of β3-adrenergic receptor mRNA in man
-
Krief, S., F. Lönnqvist, S. Raimbault, B. Baude, A. Van Spronsen, P. Arner, A. D. Strosberg, D. Ricquier, and L. J. Emorine. 1993. Tissue distribution of β3-adrenergic receptor mRNA in man. J. Clin. Invest. 91: 344-349.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 344-349
-
-
Krief, S.1
Lönnqvist, F.2
Raimbault, S.3
Baude, B.4
Van Spronsen, A.5
Arner, P.6
Strosberg, A.D.7
Ricquier, D.8
Emorine, L.J.9
-
32
-
-
0029823249
-
β3-Adrenoreceptor gene variant in obesity and insulin resistance
-
Shuldiner, A. R., K. Silver, J. Roth, and J. Walston. 1996. β3-Adrenoreceptor gene variant in obesity and insulin resistance. Lancet. 348: 1584-1585.
-
(1996)
Lancet
, vol.348
, pp. 1584-1585
-
-
Shuldiner, A.R.1
Silver, K.2
Roth, J.3
Walston, J.4
-
33
-
-
0029658675
-
The Trp64Arg mutation of the β3-adrenergic receptor gene has no effect on obesity phenotypes in the Quebec family study and Swedish obese subjects cohort
-
Gagnon, J., P. Mauriege, S. Roy, D. Sjöström, U. C. Chagnon, F. R. Dionne, J-M. Oppert, L. Perusse, L. Sjöström, and C. Bouchard. 1996. The Trp64Arg mutation of the β3-adrenergic receptor gene has no effect on obesity phenotypes in the Quebec family study and Swedish obese subjects cohort. J. Clin. Invest. 98: 2086-2093.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2086-2093
-
-
Gagnon, J.1
Mauriege, P.2
Roy, S.3
Sjöström, D.4
Chagnon, U.C.5
Dionne, F.R.6
Oppert, J.-M.7
Perusse, L.8
Sjöström, L.9
Bouchard, C.10
-
34
-
-
0028856750
-
Mutation of β3-adrenergic-receptor gene and response to treatment of obesity
-
Yoshida, T., N. Sakane, T. Umekawa, M. Sekal, T. Takahashi, and M. Rondo. 1995. Mutation of β3-adrenergic-receptor gene and response to treatment of obesity. Lancet. 346: 1433-1434.
-
(1995)
Lancet
, vol.346
, pp. 1433-1434
-
-
Yoshida, T.1
Sakane, N.2
Umekawa, T.3
Sekal, M.4
Takahashi, T.5
Rondo, M.6
-
35
-
-
0029131574
-
Expression of ob mRNA and its encoded protein in rodents: Impact of nutrition and obesity
-
Frederich, R. C., B. Lollmann, A. Hamann, A. Napolitano-Rosen, B. B. Kahn, B. B. Lowell, and J. S. Flier. 1995. Expression of ob mRNA and its encoded protein in rodents: impact of nutrition and obesity. J. Clin. Invest. 96: 1658-1663.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1658-1663
-
-
Frederich, R.C.1
Lollmann, B.2
Hamann, A.3
Napolitano-Rosen, A.4
Kahn, B.B.5
Lowell, B.B.6
Flier, J.S.7
-
36
-
-
0028793697
-
Leptin levels reflect lipid content in mice: Evidence for diet-induced resistance to leptin action
-
Frederich, R. C., A. Hamann, S. Anderson, B. Lollmann, B. B. Lowell, and J. S. Flier. Leptin levels reflect lipid content in mice: evidence for diet-induced resistance to leptin action. Nature Med. 1: 1311-1314.
-
Nature Med.
, vol.1
, pp. 1311-1314
-
-
Frederich, R.C.1
Hamann, A.2
Anderson, S.3
Lollmann, B.4
Lowell, B.B.5
Flier, J.S.6
-
37
-
-
0027731309
-
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
-
Lowell, B. B., V. S. Susulic, A. Hamann, J. A. Lawitts, J. Himms-Hagen, B. B. Boyer, L. P. Kozak, and J. S. Flier. 1993. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature. 366: 740-742.
-
(1993)
Nature
, vol.366
, pp. 740-742
-
-
Lowell, B.B.1
Susulic, V.S.2
Hamann, A.3
Lawitts, J.A.4
Himms-Hagen, J.5
Boyer, B.B.6
Kozak, L.P.7
Flier, J.S.8
-
38
-
-
0030876056
-
Chronic leptin treatment does not prevent the development of obesity in transgenic mice with brown fat deficiency
-
Hamann, A., B. Büsing, C. Kausch, J. Ertl, G. Preibisch, H. Greten, and S. Matthaei. 1997. Chronic leptin treatment does not prevent the development of obesity in transgenic mice with brown fat deficiency. Diabetologia. 40: 810-815.
-
(1997)
Diabetologia
, vol.40
, pp. 810-815
-
-
Hamann, A.1
Büsing, B.2
Kausch, C.3
Ertl, J.4
Preibisch, G.5
Greten, H.6
Matthaei, S.7
-
39
-
-
1842409029
-
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
-
Enerbäck, S., A. Jacobsson, E. M. Simpson, C. Guerra, H. Yamashita, M-E. Harper, and L. P. Kozak. 1997. Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature. 387: 90-94.
-
(1997)
Nature
, vol.387
, pp. 90-94
-
-
Enerbäck, S.1
Jacobsson, A.2
Simpson, E.M.3
Guerra, C.4
Yamashita, H.5
Harper, M.-E.6
Kozak, L.P.7
-
40
-
-
0030987368
-
Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation
-
Zhou, Y.-T., M. Shimabukuro, K. Koyama, Y. Lee, M-Y. Wang, F. Trieu, C. B. Newgard, and R. H. Unger. 1997. Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. Proc. Natl. Acad. Sci. USA. 94: 6386-6390.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6386-6390
-
-
Zhou, Y.-T.1
Shimabukuro, M.2
Koyama, K.3
Lee, Y.4
Wang, M.-Y.5
Trieu, F.6
Newgard, C.B.7
Unger, R.H.8
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