G Protein-Coupled Receptor Internalization Signaling Is Required for Cardioprotection in Ischemic Preconditioning

Circulation Research

Volumn 94, Issue 8, 2004, Pages 1133-1141

  Tong, Haiyan ^a,b   Rockman, Howard A ^b   Koch, Walter J ^b,c   Steenbergen, Charles ^b   Murphy, Elizabeth ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

G ; Ischemic preconditioning; Isolated heart; Phosphatidylinositol 3 kinase; Transgenic mice

Indexed keywords

BAFILOMYCIN A1; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; S6 KINASE; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOSOME; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE PRESSURE; HEART PROTECTION; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOCYTOSIS; ENDOSOMES; ENZYME INHIBITORS; FEMALE; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; ISOENZYMES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIAL INFARCTION; PERTUSSIS TOXIN; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS;

EID: 2342516104     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000126048.32383.6B     Document Type: Article

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