-
1
-
-
33846637379
-
Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies
-
Sarwar, N., J. Danesh, G. Eiriksdottir, G. Sigurdsson, N. Wareham, S. Bingham, S. M. Boekholdt, K. T. Khaw, and V. Gudnason. 2007. Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation. 115: 450-458.
-
(2007)
Circulation
, vol.115
, pp. 450-458
-
-
Sarwar, N.1
Danesh, J.2
Eiriksdottir, G.3
Sigurdsson, G.4
Wareham, N.5
Bingham, S.6
Boekholdt, S.M.7
Khaw, K.T.8
Gudnason, V.9
-
2
-
-
34547858847
-
High-density lipoprotein as a therapeutic target: A systematic review
-
Singh, I. M., M. H. Shishehbor, and B. J. Ansell. 2007. High-density lipoprotein as a therapeutic target: a systematic review. JAMA. 298: 786-798.
-
(2007)
JAMA
, vol.298
, pp. 786-798
-
-
Singh, I.M.1
Shishehbor, M.H.2
Ansell, B.J.3
-
3
-
-
0016630250
-
Clofibrate and niacin in coronary heart disease
-
1975. Clofibrate and niacin in coronary heart disease. JAMA. 231: 360-381.
-
(1975)
JAMA
, vol.231
, pp. 360-381
-
-
-
4
-
-
0034604225
-
Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: The Bezafibrate Infarction Prevention (BIP) study
-
2000. Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study. Circulation. 102: 21-27.
-
(2000)
Circulation
, vol.102
, pp. 21-27
-
-
-
5
-
-
0035969564
-
Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
-
Brown, B. G., X. Q. Zhao, A. Chait, L. D. Fisher, M. C. Cheung, J. S. Morse, A. A. Dowdy, E. K. Marino, E. L. Bolson, P. Alaupovic, et al. 2001. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N. Engl. J. Med. 345: 1583-1592.
-
(2001)
N. Engl. J. Med
, vol.345
, pp. 1583-1592
-
-
Brown, B.G.1
Zhao, X.Q.2
Chait, A.3
Fisher, L.D.4
Cheung, M.C.5
Morse, J.S.6
Dowdy, A.A.7
Marino, E.K.8
Bolson, E.L.9
Alaupovic, P.10
-
6
-
-
0023001772
-
Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin
-
Canner, P. L., K. G. Berge, N. K. Wenger, J. Stamler, L. Friedman, R. J. Prineas, and W. Friedewald. 1986. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J. Am. Coll. Cardiol. 8: 1245-1255.
-
(1986)
J. Am. Coll. Cardiol
, vol.8
, pp. 1245-1255
-
-
Canner, P.L.1
Berge, K.G.2
Wenger, N.K.3
Stamler, J.4
Friedman, L.5
Prineas, R.J.6
Friedewald, W.7
-
7
-
-
0023232216
-
Helsinki Heart Study: Primary-prevention trial with gemfi brozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
-
Frick, M. H., O. Elo, K. Haapa, O. P. Heinonen, P. Heinsalmi, P. Helo, J. K. Huttunen, P. Kaitaniemi, P. Koskinen, V. Manninen, et al. 1987. Helsinki Heart Study: primary-prevention trial with gemfi brozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N. Engl. J. Med. 317: 1237-1245.
-
(1987)
N. Engl. J. Med
, vol.317
, pp. 1237-1245
-
-
Frick, M.H.1
Elo, O.2
Haapa, K.3
Heinonen, O.P.4
Heinsalmi, P.5
Helo, P.6
Huttunen, J.K.7
Kaitaniemi, P.8
Koskinen, P.9
Manninen, V.10
-
9
-
-
0033527030
-
Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
-
Rubins, H. B., S. J. Robins, D. Collins, C. L. Fye, J. W. Anderson, M. B. Elam, F. H. Faas, E. Linares, E. J. Schaefer, G. Schectman, et al. 1999. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N. Engl. J. Med. 341: 410-418.
-
(1999)
N. Engl. J. Med
, vol.341
, pp. 410-418
-
-
Rubins, H.B.1
Robins, S.J.2
Collins, D.3
Fye, C.L.4
Anderson, J.W.5
Elam, M.B.6
Faas, F.H.7
Linares, E.8
Schaefer, E.J.9
Schectman, G.10
-
10
-
-
41149170003
-
Niacin use and cutaneous flushing: Mechanisms and strategies for prevention
-
Davidson, M. H. 2008. Niacin use and cutaneous flushing: mechanisms and strategies for prevention. Am. J. Cardiol. 101: 14B-19B.
-
(2008)
Am. J. Cardiol
, vol.101
-
-
Davidson, M.H.1
-
12
-
-
0037417218
-
Effects of nonstatin lipid drug therapy on high-density lipoprotein metabolism
-
Rader, D. J. 2003. Effects of nonstatin lipid drug therapy on high-density lipoprotein metabolism. Am. J. Cardiol. 91: 18E-23E.
-
(2003)
Am. J. Cardiol
, vol.91
-
-
Rader, D.J.1
-
13
-
-
33645566760
-
Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: Systematic review
-
Hooper, L., R. L. Thompson, R. A. Harrison, C. D. Summerbell, A. R. Ness, H. J. Moore, H. V. Worthington, P. N. Durrington, J. P. Higgins, N. E. Capps, et al. 2006. Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. BMJ. 332: 755-760.
-
(2006)
BMJ
, vol.332
, pp. 755-760
-
-
Hooper, L.1
Thompson, R.L.2
Harrison, R.A.3
Summerbell, C.D.4
Ness, A.R.5
Moore, H.J.6
Worthington, H.V.7
Durrington, P.N.8
Higgins, J.P.9
Capps, N.E.10
-
14
-
-
0037317469
-
Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
-
Kris-Etherton, P. M., W. S. Harris, and L. J. Appel. 2003. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Arterioscler. Thromb. Vasc. Biol. 23: e20-e30.
-
(2003)
Arterioscler. Thromb. Vasc. Biol
, vol.23
-
-
Kris-Etherton, P.M.1
Harris, W.S.2
Appel, L.J.3
-
15
-
-
33748178360
-
Genetics of high-density lipoproteins
-
Dastani, Z., J. C. Engert, J. Genest, and M. Marcil. 2006. Genetics of high-density lipoproteins. Curr. Opin. Cardiol. 21: 329-335.
-
(2006)
Curr. Opin. Cardiol
, vol.21
, pp. 329-335
-
-
Dastani, Z.1
Engert, J.C.2
Genest, J.3
Marcil, M.4
-
16
-
-
11844280278
-
Genetics of variation in HDL cholesterol in humans and mice
-
Wang, X., and B. Paigen. 2005. Genetics of variation in HDL cholesterol in humans and mice. Circ. Res. 96: 27-42.
-
(2005)
Circ. Res
, vol.96
, pp. 27-42
-
-
Wang, X.1
Paigen, B.2
-
17
-
-
35748938784
-
A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study
-
Kathiresan, S., A. K. Manning, S. Demissie, R. B. D'Agostino, A. Surti, C. Guiducci, L. Gianniny, N. P. Burtt, O. Melander, M. Orho-Melander, et al. 2007. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Med. Genet. 8 (Suppl. 1): S17.
-
(2007)
BMC Med. Genet
, vol.8
, Issue.SUPPL. 1
-
-
Kathiresan, S.1
Manning, A.K.2
Demissie, S.3
D'Agostino, R.B.4
Surti, A.5
Guiducci, C.6
Gianniny, L.7
Burtt, N.P.8
Melander, O.9
Orho-Melander, M.10
-
18
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
Willer, C. J., S. Sanna, A. U. Jackson, A. Scuteri, L. L. Bonnycastle, R. Clarke, S. C. Heath, N. J. Timpson, S. S. Najjar, H. M. Stringham, et al. 2008. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat. Genet. 40: 161-169.
-
(2008)
Nat. Genet
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
Heath, S.C.7
Timpson, N.J.8
Najjar, S.S.9
Stringham, H.M.10
-
19
-
-
59249102911
-
-
Deo, R. C., D. Reich, A. Tandon, E. Akylbekova, N. Patterson, A. Waliszewska, S. Kathiresan, D. Sarpong, H. A. Taylor, Jr., and J. G. Wilson. 2009. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet. 5: e1000342.
-
Deo, R. C., D. Reich, A. Tandon, E. Akylbekova, N. Patterson, A. Waliszewska, S. Kathiresan, D. Sarpong, H. A. Taylor, Jr., and J. G. Wilson. 2009. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet. 5: e1000342.
-
-
-
-
20
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
Kathiresan, S., O. Melander, C. Guiducci, A. Surti, N. P. Burtt, M. J. Rieder, G. M. Cooper, C. Roos, B. F. Voight, A. S. Havulinna, et al. 2008. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat. Genet. 40: 189-197.
-
(2008)
Nat. Genet
, vol.40
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, M.J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
-
21
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan, S., C. J. Willer, G. M. Peloso, S. Demissie, K. Musunuru, E. E. Schadt, L. Kaplan, D. Bennett, Y. Li, T. Tanaka, et al. 2009. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat. Genet. 41: 56-65.
-
(2009)
Nat. Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
Demissie, S.4
Musunuru, K.5
Schadt, E.E.6
Kaplan, L.7
Bennett, D.8
Li, Y.9
Tanaka, T.10
-
22
-
-
38649084407
-
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
-
Kooner, J. S., J. C. Chambers, C. A. Aguilar-Salinas, D. A. Hinds, C. L. Hyde, G. R. Warnes, F. J. Gomez Perez, K. A. Frazer, P. Elliott, J. Scott, et al. 2008. Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat. Genet. 40: 149-151.
-
(2008)
Nat. Genet
, vol.40
, pp. 149-151
-
-
Kooner, J.S.1
Chambers, J.C.2
Aguilar-Salinas, C.A.3
Hinds, D.A.4
Hyde, C.L.5
Warnes, G.R.6
Gomez Perez, F.J.7
Frazer, K.A.8
Elliott, P.9
Scott, J.10
-
23
-
-
38649110731
-
A treasure trove for lipoprotein biology
-
Lusis, A. J., and P. Pajukanta. 2008. A treasure trove for lipoprotein biology. Nat. Genet. 40: 129-130.
-
(2008)
Nat. Genet
, vol.40
, pp. 129-130
-
-
Lusis, A.J.1
Pajukanta, P.2
-
24
-
-
38749149611
-
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: Serum urate and dyslipidemia
-
Wallace, C., S. J. Newhouse, P. Braund, F. Zhang, M. Tobin, M. Falchi, K. Ahmadi, R. J. Dobson, A. C. Marcano, C. Hajat, et al. 2008. Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am. J. Hum. Genet. 82: 139-149.
-
(2008)
Am. J. Hum. Genet
, vol.82
, pp. 139-149
-
-
Wallace, C.1
Newhouse, S.J.2
Braund, P.3
Zhang, F.4
Tobin, M.5
Falchi, M.6
Ahmadi, K.7
Dobson, R.J.8
Marcano, A.C.9
Hajat, C.10
-
25
-
-
58149161560
-
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
-
Aulchenko, Y. S., S. Ripatti, I. Lindqvist, D. Boomsma, I. M. Heid, P. P. Pramstaller, B. W. Penninx, A. C. Janssens, J. F. Wilson, T. Spector, et al. 2009. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat. Genet. 41: 47-55.
-
(2009)
Nat. Genet
, vol.41
, pp. 47-55
-
-
Aulchenko, Y.S.1
Ripatti, S.2
Lindqvist, I.3
Boomsma, D.4
Heid, I.M.5
Pramstaller, P.P.6
Penninx, B.W.7
Janssens, A.C.8
Wilson, J.F.9
Spector, T.10
-
26
-
-
58149159573
-
-
Sabatti, C., S. K. Service, A. L. Hartikainen, A. Pouta, S. Ripatti, J. Brodsky, C. G. Jones, N. A. Zaitlen, T. Varilo, M. Kaakinen, et al. 2009. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat. Genet. 41: 35-46.
-
Sabatti, C., S. K. Service, A. L. Hartikainen, A. Pouta, S. Ripatti, J. Brodsky, C. G. Jones, N. A. Zaitlen, T. Varilo, M. Kaakinen, et al. 2009. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat. Genet. 41: 35-46.
-
-
-
-
27
-
-
33748519211
-
In search of new targets for plasma high-density lipoprotein cholesterol levels: Promise of human-mouse comparative genomics
-
Rollins, J., Y. Chen, B. Paigen, and X. Wang. 2006. In search of new targets for plasma high-density lipoprotein cholesterol levels: promise of human-mouse comparative genomics. Trends Cardiovasc. Med. 16: 220-234.
-
(2006)
Trends Cardiovasc. Med
, vol.16
, pp. 220-234
-
-
Rollins, J.1
Chen, Y.2
Paigen, B.3
Wang, X.4
-
28
-
-
58149467316
-
Differences in DBA/1J and DBA/2J reveal lipid QTL genes
-
Stylianou, I. M., S. R. Langley, K. Walsh, Y. Chen, C. Revenu, and B. Paigen. 2008. Differences in DBA/1J and DBA/2J reveal lipid QTL genes. J. Lipid Res. 49: 2402-2413.
-
(2008)
J. Lipid Res
, vol.49
, pp. 2402-2413
-
-
Stylianou, I.M.1
Langley, S.R.2
Walsh, K.3
Chen, Y.4
Revenu, C.5
Paigen, B.6
-
29
-
-
27744519434
-
Bioinformatics toolbox for narrowing rodent quantitative trait loci
-
DiPetrillo, K., X. Wang, I. M. Stylianou, and B. Paigen. 2005. Bioinformatics toolbox for narrowing rodent quantitative trait loci. Trends Genet. 21: 683-692.
-
(2005)
Trends Genet
, vol.21
, pp. 683-692
-
-
DiPetrillo, K.1
Wang, X.2
Stylianou, I.M.3
Paigen, B.4
-
30
-
-
36049051389
-
Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice
-
Sheehan, S., S. W. Tsaih, B. L. King, C. Stanton, G. A. Churchill, B. Paigen, and K. DiPetrillo. 2007. Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice. Am. J. Physiol. Renal Physiol. 293: F1649-F1656.
-
(2007)
Am. J. Physiol. Renal Physiol
, vol.293
-
-
Sheehan, S.1
Tsaih, S.W.2
King, B.L.3
Stanton, C.4
Churchill, G.A.5
Paigen, B.6
DiPetrillo, K.7
-
31
-
-
0033787384
-
Maternal environment and genotype interact to establish diabesity in mice
-
Reifsnyder, P. C., G. Churchill, and E. H. Leiter. 2000. Maternal environment and genotype interact to establish diabesity in mice. Genome Res. 10: 1568-1578.
-
(2000)
Genome Res
, vol.10
, pp. 1568-1578
-
-
Reifsnyder, P.C.1
Churchill, G.2
Leiter, E.H.3
-
32
-
-
50949088445
-
Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJ
-
Su, Z., S. W. Tsaih, J. Szatkiewicz, Y. Shen, and B. Paigen. 2008. Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJ. J. Lipid Res. 49: 1500-1510.
-
(2008)
J. Lipid Res
, vol.49
, pp. 1500-1510
-
-
Su, Z.1
Tsaih, S.W.2
Szatkiewicz, J.3
Shen, Y.4
Paigen, B.5
-
33
-
-
47249116535
-
Candidate genes for obesity revealed from a C57BL/6J × 129S1/SvImJ intercross
-
Su, Z., R. Korstanje, S. W. Tsaih, and B. Paigen. 2008. Candidate genes for obesity revealed from a C57BL/6J × 129S1/SvImJ intercross. Int. J. Obes. (Lond). 32: 1180-1189.
-
(2008)
Int. J. Obes. (Lond)
, vol.32
, pp. 1180-1189
-
-
Su, Z.1
Korstanje, R.2
Tsaih, S.W.3
Paigen, B.4
-
34
-
-
0028151261
-
Empirical threshold values for quantitative trait mapping
-
Churchill, G. A., and R. W. Doerge. 1994. Empirical threshold values for quantitative trait mapping. Genetics. 138: 963-971.
-
(1994)
Genetics
, vol.138
, pp. 963-971
-
-
Churchill, G.A.1
Doerge, R.W.2
-
35
-
-
33644656566
-
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse
-
Moran, J. L., A. D. Bolton, P. V. Tran, A. Brown, N. D. Dwyer, D. K. Manning, B. C. Bjork, C. Li, K. Montgomery, S. M. Siepka, et al. 2006. Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. Genome Res. 16: 436-440.
-
(2006)
Genome Res
, vol.16
, pp. 436-440
-
-
Moran, J.L.1
Bolton, A.D.2
Tran, P.V.3
Brown, A.4
Dwyer, N.D.5
Manning, D.K.6
Bjork, B.C.7
Li, C.8
Montgomery, K.9
Siepka, S.M.10
-
36
-
-
17144370488
-
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping
-
Li, R., M. A. Lyons, H. Wittenburg, B. Paigen, and G. A. Churchill. 2005. Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping. Genetics. 169: 1699-1709.
-
(2005)
Genetics
, vol.169
, pp. 1699-1709
-
-
Li, R.1
Lyons, M.A.2
Wittenburg, H.3
Paigen, B.4
Churchill, G.A.5
-
37
-
-
34548295740
-
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains
-
Frazer, K. A., E. Eskin, H. M. Kang, M. A. Bogue, D. A. Hinds, E. J. Beilharz, R. V. Gupta, J. Montgomery, M. M. Morenzoni, G. B. Nilsen, et al. 2007. A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature. 448: 1050-1053.
-
(2007)
Nature
, vol.448
, pp. 1050-1053
-
-
Frazer, K.A.1
Eskin, E.2
Kang, H.M.3
Bogue, M.A.4
Hinds, D.A.5
Beilharz, E.J.6
Gupta, R.V.7
Montgomery, J.8
Morenzoni, M.M.9
Nilsen, G.B.10
-
38
-
-
52449135524
-
An imputed genotype resource for the laboratory mouse
-
Szatkiewicz, J. P., G. L. Beane, Y. Ding, L. Hutchins, F. Pardo-Manuel de Villena, and G. A. Churchill. 2008. An imputed genotype resource for the laboratory mouse. Mamm. Genome. 19: 199-208.
-
(2008)
Mamm. Genome
, vol.19
, pp. 199-208
-
-
Szatkiewicz, J.P.1
Beane, G.L.2
Ding, Y.3
Hutchins, L.4
Pardo-Manuel de Villena, F.5
Churchill, G.A.6
-
39
-
-
0037452982
-
Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse
-
Wiltshire, T., M. T. Pletcher, S. Batalov, S. W. Barnes, L. M. Tarantino, M. P. Cooke, H. Wu, K. Smylie, A. Santrosyan, N. G. Copeland, et al. 2003. Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc. Natl. Acad. Sci. USA. 100: 3380-3385.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3380-3385
-
-
Wiltshire, T.1
Pletcher, M.T.2
Batalov, S.3
Barnes, S.W.4
Tarantino, L.M.5
Cooke, M.P.6
Wu, H.7
Smylie, K.8
Santrosyan, A.9
Copeland, N.G.10
-
40
-
-
45149115741
-
Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification
-
Stylianou, I. M., J. P. Affourtit, K. R. Shockley, R. Y. Wilpan, F. A. Abdi, S. Bhardwaj, J. Rollins, G. A. Churchill, and B. Paigen. 2008. Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification. Genetics. 178: 1795-1805.
-
(2008)
Genetics
, vol.178
, pp. 1795-1805
-
-
Stylianou, I.M.1
Affourtit, J.P.2
Shockley, K.R.3
Wilpan, R.Y.4
Abdi, F.A.5
Bhardwaj, S.6
Rollins, J.7
Churchill, G.A.8
Paigen, B.9
-
41
-
-
4644219642
-
Haplotype analysis in multiple crosses to identify a QTL gene
-
Wang, X., R. Korstanje, D. Higgins, and B. Paigen. 2004. Haplotype analysis in multiple crosses to identify a QTL gene. Genome Res. 14: 1767-1772.
-
(2004)
Genome Res
, vol.14
, pp. 1767-1772
-
-
Wang, X.1
Korstanje, R.2
Higgins, D.3
Paigen, B.4
-
42
-
-
58849139151
-
Farp2 and Stk25 are candidate genes for the HDL cholesterol locus on mouse chromosome 1
-
Su, Z., A. Cox, Y. Shen, I. M. Stylianou, and B. Paigen. 2009. Farp2 and Stk25 are candidate genes for the HDL cholesterol locus on mouse chromosome 1. Arterioscler. Thromb. Vasc. Biol. 29: 107-113.
-
(2009)
Arterioscler. Thromb. Vasc. Biol
, vol.29
, pp. 107-113
-
-
Su, Z.1
Cox, A.2
Shen, Y.3
Stylianou, I.M.4
Paigen, B.5
-
43
-
-
33745495993
-
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: Relation to dysregulated phosphatidylcholine metabolism
-
Pan, H. J., Y. Lin, Y. E. Chen, D. E. Vance, and E. H. Leiter. 2006. Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism. Vascul. Pharmacol. 45: 65-71.
-
(2006)
Vascul. Pharmacol
, vol.45
, pp. 65-71
-
-
Pan, H.J.1
Lin, Y.2
Chen, Y.E.3
Vance, D.E.4
Leiter, E.H.5
-
44
-
-
0038449114
-
Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice
-
Colinayo, V. V., J. H. Qiao, X. Wang, K. L. Krass, E. Schadt, A. J. Lusis, and T. A. Drake. 2003. Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice. Mamm. Genome. 14: 464-471.
-
(2003)
Mamm. Genome
, vol.14
, pp. 464-471
-
-
Colinayo, V.V.1
Qiao, J.H.2
Wang, X.3
Krass, K.L.4
Schadt, E.5
Lusis, A.J.6
Drake, T.A.7
-
45
-
-
0035287508
-
Modifi er genes in mice and humans
-
Nadeau, J. H. 2001. Modifi er genes in mice and humans. Nat. Rev. Genet. 2: 165-174.
-
(2001)
Nat. Rev. Genet
, vol.2
, pp. 165-174
-
-
Nadeau, J.H.1
-
46
-
-
23744479594
-
A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships
-
Kullo, I. J., S. T. Turner, E. Boerwinkle, S. L. Kardia, and M. de Andrade. 2005. A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships. Am. J. Hypertens. 18: 1084-1090.
-
(2005)
Am. J. Hypertens
, vol.18
, pp. 1084-1090
-
-
Kullo, I.J.1
Turner, S.T.2
Boerwinkle, E.3
Kardia, S.L.4
de Andrade, M.5
-
47
-
-
0037204994
-
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome
-
Mural, R. J., M. D. Adams, E. W. Myers, H. O. Smith, G. L. Miklos, R. Wides, A. Halpern, P. W. Li, G. G. Sutton, J. Nadeau, et al. 2002. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science. 296: 1661-1671.
-
(2002)
Science
, vol.296
, pp. 1661-1671
-
-
Mural, R.J.1
Adams, M.D.2
Myers, E.W.3
Smith, H.O.4
Miklos, G.L.5
Wides, R.6
Halpern, A.7
Li, P.W.8
Sutton, G.G.9
Nadeau, J.10
-
48
-
-
0035671407
-
The genetic architecture of quantitative traits
-
Mackay, T. F. 2001. The genetic architecture of quantitative traits. Annu. Rev. Genet. 35: 303-339.
-
(2001)
Annu. Rev. Genet
, vol.35
, pp. 303-339
-
-
Mackay, T.F.1
-
49
-
-
11844254278
-
Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice
-
Yalcin, B., S. A. Willis-Owen, J. Fullerton, A. Meesaq, R. M. Deacon, J. N. Rawlins, R. R. Copley, A. P. Morris, J. Flint, and R. Mott. 2004. Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Nat. Genet. 36: 1197-1202.
-
(2004)
Nat. Genet
, vol.36
, pp. 1197-1202
-
-
Yalcin, B.1
Willis-Owen, S.A.2
Fullerton, J.3
Meesaq, A.4
Deacon, R.M.5
Rawlins, J.N.6
Copley, R.R.7
Morris, A.P.8
Flint, J.9
Mott, R.10
-
50
-
-
33748894674
-
Sometimes the result is not the answer: The truths and the lies that come from using the complementation test
-
Hawley, R. S., and W. D. Gilliland. 2006. Sometimes the result is not the answer: the truths and the lies that come from using the complementation test. Genetics. 174: 5-15.
-
(2006)
Genetics
, vol.174
, pp. 5-15
-
-
Hawley, R.S.1
Gilliland, W.D.2
-
51
-
-
0344406740
-
Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism
-
Ma, K., M. Cilingiroglu, J. D. Otvos, C. M. Ballantyne, A. J. Marian, and L. Chan. 2003. Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc. Natl. Acad. Sci. USA. 100: 2748-2753.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2748-2753
-
-
Ma, K.1
Cilingiroglu, M.2
Otvos, J.D.3
Ballantyne, C.M.4
Marian, A.J.5
Chan, L.6
-
52
-
-
63449123597
-
Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: Importance of testing candidate genes in targeted mutant mice
-
Su, Z., X. Wang, S. W. Tsaih, A. Zhang, A. Cox, S. Sheehan, and B. Paigen. 2009. Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice. J. Lipid Res. 50: 116-125.
-
(2009)
J. Lipid Res
, vol.50
, pp. 116-125
-
-
Su, Z.1
Wang, X.2
Tsaih, S.W.3
Zhang, A.4
Cox, A.5
Sheehan, S.6
Paigen, B.7
-
53
-
-
0031087023
-
Interval-specifi c congenic strains (ISCS): An experimental design for mapping a QTL into a 1-centimorgan interval
-
Darvasi, A. 1997. Interval-specifi c congenic strains (ISCS): an experimental design for mapping a QTL into a 1-centimorgan interval. Mamm. Genome. 8: 163-167.
-
(1997)
Mamm. Genome
, vol.8
, pp. 163-167
-
-
Darvasi, A.1
-
54
-
-
66249146060
-
A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci
-
Gale, G. D., R. D. Yazdi, A. H. Khan, A. J. Lusis, R. C. Davis, and D. J. Smith. 2008. A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci. Mol. Psychiatry. 14: 631-645.
-
(2008)
Mol. Psychiatry
, vol.14
, pp. 631-645
-
-
Gale, G.D.1
Yazdi, R.D.2
Khan, A.H.3
Lusis, A.J.4
Davis, R.C.5
Smith, D.J.6
-
55
-
-
33750478317
-
Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses
-
Stylianou, I. M., S. W. Tsaih, K. DiPetrillo, N. Ishimori, R. Li, B. Paigen, and G. Churchill. 2006. Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses. Genetics. 174: 999-1007.
-
(2006)
Genetics
, vol.174
, pp. 999-1007
-
-
Stylianou, I.M.1
Tsaih, S.W.2
DiPetrillo, K.3
Ishimori, N.4
Li, R.5
Paigen, B.6
Churchill, G.7
-
56
-
-
33749017409
-
The human obesity gene map: The 2005 update
-
Rankinen, T., A. Zuberi, Y. C. Chagnon, S. J. Weisnagel, G. Argyropoulos, B. Walts, L. Perusse, and C. Bouchard. 2006. The human obesity gene map: the 2005 update. Obesity (Silver Spring). 14: 529-644.
-
(2006)
Obesity (Silver Spring)
, vol.14
, pp. 529-644
-
-
Rankinen, T.1
Zuberi, A.2
Chagnon, Y.C.3
Weisnagel, S.J.4
Argyropoulos, G.5
Walts, B.6
Perusse, L.7
Bouchard, C.8
-
57
-
-
20544467972
-
Identifying novel genes for atherosclerosis through mouse-human comparative genetics
-
Wang, X., N. Ishimori, R. Korstanje, J. Rollins, and B. Paigen. 2005. Identifying novel genes for atherosclerosis through mouse-human comparative genetics. Am. J. Hum. Genet. 77: 1-15.
-
(2005)
Am. J. Hum. Genet
, vol.77
, pp. 1-15
-
-
Wang, X.1
Ishimori, N.2
Korstanje, R.3
Rollins, J.4
Paigen, B.5
-
58
-
-
0242286640
-
Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase
-
Maugeais, C., U. J. Tietge, U. C. Broedl, D. Marchadier, W. Cain, M. G. McCoy, S. Lund-Katz, J. M. Glick, and D. J. Rader. 2003. Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase. Circulation. 108: 2121-2126.
-
(2003)
Circulation
, vol.108
, pp. 2121-2126
-
-
Maugeais, C.1
Tietge, U.J.2
Broedl, U.C.3
Marchadier, D.4
Cain, W.5
McCoy, M.G.6
Lund-Katz, S.7
Glick, J.M.8
Rader, D.J.9
-
59
-
-
0037314398
-
Endothelial lipase is a major determinant of HDL level
-
Ishida, T., S. Choi, R. K. Kundu, K. Hirata, E. M. Rubin, A. D. Cooper, and T. Quertermous. 2003. Endothelial lipase is a major determinant of HDL level. J. Clin. Invest. 111: 347-355.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 347-355
-
-
Ishida, T.1
Choi, S.2
Kundu, R.K.3
Hirata, K.4
Rubin, E.M.5
Cooper, A.D.6
Quertermous, T.7
-
60
-
-
10044225895
-
Compendium of genome-wide scans of lipid-related phenotypes: Adding a new genomewide search of apolipoprotein levels
-
Bosse, Y., Y. C. Chagnon, J. P. Despres, T. Rice, D. C. Rao, C. Bouchard, L. Perusse, and M. C. Vohl. 2004. Compendium of genome-wide scans of lipid-related phenotypes: adding a new genomewide search of apolipoprotein levels. J. Lipid Res. 45: 2174-2184.
-
(2004)
J. Lipid Res
, vol.45
, pp. 2174-2184
-
-
Bosse, Y.1
Chagnon, Y.C.2
Despres, J.P.3
Rice, T.4
Rao, D.C.5
Bouchard, C.6
Perusse, L.7
Vohl, M.C.8
-
61
-
-
27244458482
-
Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I
-
Jahangiri, A., D. J. Rader, D. Marchadier, L. K. Curtiss, D. J. Bonnet, and K. A. Rye. 2005. Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I. J. Lipid Res. 46: 896-903.
-
(2005)
J. Lipid Res
, vol.46
, pp. 896-903
-
-
Jahangiri, A.1
Rader, D.J.2
Marchadier, D.3
Curtiss, L.K.4
Bonnet, D.J.5
Rye, K.A.6
-
62
-
-
30944449662
-
Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans
-
Hutter, C. M., M. A. Austin, F. M. Farin, H. M. Viernes, K. L. Edwards, D. L. Leonetti, M. J. McNeely, and W. Y. Fujimoto. 2006. Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans. Atherosclerosis. 185: 78-86.
-
(2006)
Atherosclerosis
, vol.185
, pp. 78-86
-
-
Hutter, C.M.1
Austin, M.A.2
Farin, F.M.3
Viernes, H.M.4
Edwards, K.L.5
Leonetti, D.L.6
McNeely, M.J.7
Fujimoto, W.Y.8
-
63
-
-
1242292260
-
Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels
-
Mank-Seymour, A. R., K. L. Durham, J. F. Thompson, A. B. Seymour, and P. M. Milos. 2004. Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels. Biochim. Biophys. Acta. 1636: 40-46.
-
(2004)
Biochim. Biophys. Acta
, vol.1636
, pp. 40-46
-
-
Mank-Seymour, A.R.1
Durham, K.L.2
Thompson, J.F.3
Seymour, A.B.4
Milos, P.M.5
-
64
-
-
65249186429
-
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
-
Edmondson, A. C., R. J. Brown, S. Kathiresan, L. A. Cupples, S. Demissie, A. K. Manning, M. K. Jensen, E. B. Rimm, J. Wang, A. Rodrigues, et al. 2009. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J. Clin. Invest. 119: 1042-1050.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 1042-1050
-
-
Edmondson, A.C.1
Brown, R.J.2
Kathiresan, S.3
Cupples, L.A.4
Demissie, S.5
Manning, A.K.6
Jensen, M.K.7
Rimm, E.B.8
Wang, J.9
Rodrigues, A.10
-
65
-
-
34548188837
-
Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains
-
Wergedal, J. E., C. L. Ackert-Bicknell, W. G. Beamer, S. Mohan, D. J. Baylink, and A. K. Srivastava. 2007. Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains. J. Lipid Res. 48: 1724-1734.
-
(2007)
J. Lipid Res
, vol.48
, pp. 1724-1734
-
-
Wergedal, J.E.1
Ackert-Bicknell, C.L.2
Beamer, W.G.3
Mohan, S.4
Baylink, D.J.5
Srivastava, A.K.6
-
66
-
-
36348998197
-
Genetic control of lipids in the mouse cross DU6i x DBA/2
-
Brockmann, G. A., E. Karatayli, C. Neuschl, I. M. Stylianou, S. Aksu, A. Ludwig, U. Renne, C. S. Haley, and S. Knott. 2007. Genetic control of lipids in the mouse cross DU6i x DBA/2. Mamm. Genome. 18: 757-766.
-
(2007)
Mamm. Genome
, vol.18
, pp. 757-766
-
-
Brockmann, G.A.1
Karatayli, E.2
Neuschl, C.3
Stylianou, I.M.4
Aksu, S.5
Ludwig, A.6
Renne, U.7
Haley, C.S.8
Knott, S.9
-
67
-
-
36348998626
-
Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice
-
Wang, S. S., W. Shi, X. Wang, L. Velky, S. Greenlee, M. T. Wang, T. A. Drake, and A. J. Lusis. 2007. Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. Arterioscler. Thromb. Vasc. Biol. 27: 2671-2676.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 2671-2676
-
-
Wang, S.S.1
Shi, W.2
Wang, X.3
Velky, L.4
Greenlee, S.5
Wang, M.T.6
Drake, T.A.7
Lusis, A.J.8
-
68
-
-
0030893854
-
Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism
-
Machleder, D., B. Ivandic, C. Welch, L. Castellani, K. Reue, and A. J. Lusis. 1997. Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism. J. Clin. Invest. 99: 1406-1419.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 1406-1419
-
-
Machleder, D.1
Ivandic, B.2
Welch, C.3
Castellani, L.4
Reue, K.5
Lusis, A.J.6
-
69
-
-
0034519043
-
Genetic control of HDL levels and composition in an interspecific mouse cross (CAST/Ei x C57BL/6J)
-
Mehrabian, M., L. W. Castellani, P. Z. Wen, J. Wong, T. Rithaporn, S. Y. Hama, G. P. Hough, D. Johnson, J. J. Albers, G. A. Mottino, et al. 2000. Genetic control of HDL levels and composition in an interspecific mouse cross (CAST/Ei x C57BL/6J). J. Lipid Res. 41: 1936-1946.
-
(2000)
J. Lipid Res
, vol.41
, pp. 1936-1946
-
-
Mehrabian, M.1
Castellani, L.W.2
Wen, P.Z.3
Wong, J.4
Rithaporn, T.5
Hama, S.Y.6
Hough, G.P.7
Johnson, D.8
Albers, J.J.9
Mottino, G.A.10
-
70
-
-
2142751020
-
Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population
-
Korstanje, R., R. Li, T. Howard, P. Kelmenson, J. Marshall, B. Paigen, and G. Churchill. 2004. Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population. J. Lipid Res. 45: 881-888.
-
(2004)
J. Lipid Res
, vol.45
, pp. 881-888
-
-
Korstanje, R.1
Li, R.2
Howard, T.3
Kelmenson, P.4
Marshall, J.5
Paigen, B.6
Churchill, G.7
|