메뉴 건너뛰기




Volumn 48, Issue 8, 2007, Pages 1724-1734

Mapping genetic loci that regulate lipid levels in a NZB/B1NJ3RF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains

Author keywords

Cholesterol; Combined cross linkage analysis; High density lipoprotein cholesterol; Quantitative trait loci; Triglyceride

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN;

EID: 34548188837     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700015-JLR200     Document Type: Article
Times cited : (18)

References (53)
  • 1
    • 34548165168 scopus 로고    scopus 로고
    • American Heart Association. 2003. Heart and Stroke Statistics: 2003 Update. American Heart Association, Dallas, TX.
    • American Heart Association. 2003. Heart and Stroke Statistics: 2003 Update. American Heart Association, Dallas, TX.
  • 2
    • 34548183453 scopus 로고    scopus 로고
    • National Center for Health Statistics, Centers for Disease Control and Prevention, US Department of Health and Human Services. 2003. Fast stats A to Z: leading causes of death. Accessed April 12, 2007, at http://www.cdc.gov/nchs/ fastats/lcod.htm.
    • National Center for Health Statistics, Centers for Disease Control and Prevention, US Department of Health and Human Services. 2003. Fast stats A to Z: leading causes of death. Accessed April 12, 2007, at http://www.cdc.gov/nchs/ fastats/lcod.htm.
  • 5
    • 0036605170 scopus 로고    scopus 로고
    • Significant impact of the highly informative (CA)n repeat polymorphism of the APOA-II gene on the plasma APOA-II concentrations and HDL subfractions: The ECTIM Study
    • Brousseau, T., A. M. Dupuy-Gorce, A. Evans, D. Arveiler, J. B. Ruidavets, B. Haas, J. P. Cambou, G. Luc, P. Ducimetiere, P. Amouyel, et al. 2002. Significant impact of the highly informative (CA)n repeat polymorphism of the APOA-II gene on the plasma APOA-II concentrations and HDL subfractions: the ECTIM Study. Am. J. Med. Genet. 110: 19-24.
    • (2002) Am. J. Med. Genet , vol.110 , pp. 19-24
    • Brousseau, T.1    Dupuy-Gorce, A.M.2    Evans, A.3    Arveiler, D.4    Ruidavets, J.B.5    Haas, B.6    Cambou, J.P.7    Luc, G.8    Ducimetiere, P.9    Amouyel, P.10
  • 6
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown, M. S., and J. L. Goldstein. 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 89: 331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 0028228359 scopus 로고
    • Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: Evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci
    • Bu, X., C. H. Warden, Y. R. Xia, C. De Meester, D. L. Puppione, S. Teruya, B. Lokensgard, S. Daneshmand, J. Brown, R. J. Gray, et al. 1994. Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci. Hum. Genet. 93: 639-648.
    • (1994) Hum. Genet , vol.93 , pp. 639-648
    • Bu, X.1    Warden, C.H.2    Xia, Y.R.3    De Meester, C.4    Puppione, D.L.5    Teruya, S.6    Lokensgard, B.7    Daneshmand, S.8    Brown, J.9    Gray, R.J.10
  • 11
    • 0028788492 scopus 로고
    • Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach
    • Purcell-Huynh, D. A., A. Weinreb, L. W. Castellani, M. Mehrabian, M. H. Doolittle, and A. J. Lusis. 1995. Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach. J. Clin. Invest. 96: 1845-1858.
    • (1995) J. Clin. Invest , vol.96 , pp. 1845-1858
    • Purcell-Huynh, D.A.1    Weinreb, A.2    Castellani, L.W.3    Mehrabian, M.4    Doolittle, M.H.5    Lusis, A.J.6
  • 12
    • 0031956686 scopus 로고    scopus 로고
    • Genetic analysis of the difference in diet-induced atherosclerosis between the inbred mouse strains SM/J and NZB/BINJ
    • Pitman, W. A., M. H. Hunt, C. McFarland, and B. Paigen. 1998. Genetic analysis of the difference in diet-induced atherosclerosis between the inbred mouse strains SM/J and NZB/BINJ. Arterioscler. Thromb. Vasc. Biol. 18: 615-620.
    • (1998) Arterioscler. Thromb. Vasc. Biol , vol.18 , pp. 615-620
    • Pitman, W.A.1    Hunt, M.H.2    McFarland, C.3    Paigen, B.4
  • 14
    • 4444293999 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J X RR F2 mice
    • Suto, J., Y. Takahashi, and K. Sekikawa. 2004. Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J X RR F2 mice. Biochem. Genet. 42: 347-363.
    • (2004) Biochem. Genet , vol.42 , pp. 347-363
    • Suto, J.1    Takahashi, Y.2    Sekikawa, K.3
  • 17
    • 2142751020 scopus 로고    scopus 로고
    • Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population
    • Korstanje, R., R. Li, T. Howard, P. Kelmenson, J. Marshall, B. Paigen, and G. Churchill. 2004. Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population. J. Lipid Res. 45: 881-888.
    • (2004) J. Lipid Res , vol.45 , pp. 881-888
    • Korstanje, R.1    Li, R.2    Howard, T.3    Kelmenson, P.4    Marshall, J.5    Paigen, B.6    Churchill, G.7
  • 18
    • 3843133845 scopus 로고    scopus 로고
    • Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice
    • Lyons, M. A., R. Korstanje, R. Li, K. A. Walsh, G. A. Churchill, M. C. Carey, and B. Paigen. 2004. Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice. Physiol. Genomics. 17: 114-121.
    • (2004) Physiol. Genomics , vol.17 , pp. 114-121
    • Lyons, M.A.1    Korstanje, R.2    Li, R.3    Walsh, K.A.4    Churchill, G.A.5    Carey, M.C.6    Paigen, B.7
  • 19
    • 0042995279 scopus 로고    scopus 로고
    • Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice
    • Lyons, M. A., H. Wittenburg, R. Li, K. A. Walsh, G. A. Churchill, M. C. Carey, and B. Paigen. 2003. Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice. J. Lipid Res. 44: 953-967.
    • (2003) J. Lipid Res , vol.44 , pp. 953-967
    • Lyons, M.A.1    Wittenburg, H.2    Li, R.3    Walsh, K.A.4    Churchill, G.A.5    Carey, M.C.6    Paigen, B.7
  • 20
    • 1842509784 scopus 로고    scopus 로고
    • Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice
    • Lyons, M. A., H. Wittenburg, R. Li, K. A. Walsh, R. Korstanje, G. A. Churchill, M. C. Carey, and B. Paigen. 2004. Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice. Physiol. Genomics. 17: 60-68.
    • (2004) Physiol. Genomics , vol.17 , pp. 60-68
    • Lyons, M.A.1    Wittenburg, H.2    Li, R.3    Walsh, K.A.4    Korstanje, R.5    Churchill, G.A.6    Carey, M.C.7    Paigen, B.8
  • 21
    • 0032966978 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: Interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis
    • Gu, L., M. W. Johnson, and A. J. Lusis. 1999. Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis. Arterioscler. Thromb. Vasc. Biol. 19: 442-453.
    • (1999) Arterioscler. Thromb. Vasc. Biol , vol.19 , pp. 442-453
    • Gu, L.1    Johnson, M.W.2    Lusis, A.J.3
  • 24
    • 0346727152 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in KK X RR F2 mice
    • Suto, J., and K. Sekikawa. 2003. Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in KK X RR F2 mice. Biochem. Genet. 41: 325-341.
    • (2003) Biochem. Genet , vol.41 , pp. 325-341
    • Suto, J.1    Sekikawa, K.2
  • 25
    • 0030239728 scopus 로고    scopus 로고
    • Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei X C57BL/6J F2 intercross
    • York, B., K. Lei, and D. B. West. 1996. Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei X C57BL/6J F2 intercross. Mamm. Genome. 7: 677-681.
    • (1996) Mamm. Genome , vol.7 , pp. 677-681
    • York, B.1    Lei, K.2    West, D.B.3
  • 26
    • 11844280278 scopus 로고    scopus 로고
    • Genetics of variation in HDL cholesterol in humans and mice
    • Wang, X., and B. Paigen. 2005. Genetics of variation in HDL cholesterol in humans and mice. Circ. Res. 96: 27-42.
    • (2005) Circ. Res , vol.96 , pp. 27-42
    • Wang, X.1    Paigen, B.2
  • 27
    • 0036738377 scopus 로고    scopus 로고
    • Quantitative trait loci and candidate genes regulating HDL cholesterol: A murine chromosome map
    • Wang, X., and B. Paigen. 2002. Quantitative trait loci and candidate genes regulating HDL cholesterol: a murine chromosome map. Arterioscler. Thromb. Vasc. Biol. 22: 1390-1401.
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 1390-1401
    • Wang, X.1    Paigen, B.2
  • 28
    • 30844459017 scopus 로고    scopus 로고
    • Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ X SJL/J inbred mice
    • Srivastava, A. K., S. Mohan, G. L. Masinde, H. Yu, and D. J. Baylink. 2006. Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ X SJL/J inbred mice. J. Lipid Res. 47: 123-133.
    • (2006) J. Lipid Res , vol.47 , pp. 123-133
    • Srivastava, A.K.1    Mohan, S.2    Masinde, G.L.3    Yu, H.4    Baylink, D.J.5
  • 29
    • 17144370488 scopus 로고    scopus 로고
    • Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping
    • Li, R., M. A. Lyons, H. Wittenburg, B. Paigen, and G. A. Churchill. 2005. Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping. Genetics. 169: 1699-1709.
    • (2005) Genetics , vol.169 , pp. 1699-1709
    • Li, R.1    Lyons, M.A.2    Wittenburg, H.3    Paigen, B.4    Churchill, G.A.5
  • 30
    • 33750931441 scopus 로고    scopus 로고
    • Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat
    • Jagodic, M., and T. Olsson. 2006. Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat. Genomics. 88: 737-744.
    • (2006) Genomics , vol.88 , pp. 737-744
    • Jagodic, M.1    Olsson, T.2
  • 31
    • 33747146438 scopus 로고    scopus 로고
    • QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains
    • Wittenburg, H., M. A. Lyons, R. Li, U. Kurtz, X. Wang, J. Mossner, G. A. Churchill, M. C. Carey, and B. Paigen. 2006. QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains. J. Lipid Res. 47: 1780-1790.
    • (2006) J. Lipid Res , vol.47 , pp. 1780-1790
    • Wittenburg, H.1    Lyons, M.A.2    Li, R.3    Kurtz, U.4    Wang, X.5    Mossner, J.6    Churchill, G.A.7    Carey, M.C.8    Paigen, B.9
  • 32
    • 33746401934 scopus 로고    scopus 로고
    • Femur mechanical properties in the F2 progeny of an NZB/B1NJ X RF/J cross are regulated predominantly by genetic loci that regulate bone geometry
    • Wergedal, J. E., C. L. Ackert-Bicknell, S. W. Tsaih, M. H. Sheng, R. Li, S. Mohan, W. G. Beamer, G. A. Churchill, and D. J. Baylink. 2006. Femur mechanical properties in the F2 progeny of an NZB/B1NJ X RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. J. Bone Miner. Res. 21: 1256-1266.
    • (2006) J. Bone Miner. Res , vol.21 , pp. 1256-1266
    • Wergedal, J.E.1    Ackert-Bicknell, C.L.2    Tsaih, S.W.3    Sheng, M.H.4    Li, R.5    Mohan, S.6    Beamer, W.G.7    Churchill, G.A.8    Baylink, D.J.9
  • 33
    • 0035140274 scopus 로고    scopus 로고
    • Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci
    • Sugiyama, F., G. A. Churchill, D. C. Higgins, C. Johns, K. P. Makaritsis, H. Gavras, and B. Paigen. 2001. Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics. 71: 70-77.
    • (2001) Genomics , vol.71 , pp. 70-77
    • Sugiyama, F.1    Churchill, G.A.2    Higgins, D.C.3    Johns, C.4    Makaritsis, K.P.5    Gavras, H.6    Paigen, B.7
  • 34
    • 0034817026 scopus 로고    scopus 로고
    • A statistical framework for quantitative trait mapping
    • Sen, S., and G. A. Churchill. 2001. A statistical framework for quantitative trait mapping. Genetics. 159: 371-387.
    • (2001) Genetics , vol.159 , pp. 371-387
    • Sen, S.1    Churchill, G.A.2
  • 36
    • 0034523871 scopus 로고    scopus 로고
    • Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i X DBA/2 mice
    • Brockmann, G. A., J. Kratzsch, C. S. Haley, U. Renne, M. Schwerin, and S. Karle. 2000. Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i X DBA/2 mice. Genome Res. 10: 1941-1957.
    • (2000) Genome Res , vol.10 , pp. 1941-1957
    • Brockmann, G.A.1    Kratzsch, J.2    Haley, C.S.3    Renne, U.4    Schwerin, M.5    Karle, S.6
  • 37
    • 0034652629 scopus 로고    scopus 로고
    • Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus
    • Schriml, L. M., and M. Dean. 2000. Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus. Genomics. 64: 24-31.
    • (2000) Genomics , vol.64 , pp. 24-31
    • Schriml, L.M.1    Dean, M.2
  • 38
    • 4544293838 scopus 로고    scopus 로고
    • The novel gene fad158, having a transmembrane domain and leucine-rich repeat, stimulates adipocyte differentiation
    • Tominaga, K., C. Kondo, T. Kagata, T. Hishida, M. Nishizuka, and M. Imagawa. 2004. The novel gene fad158, having a transmembrane domain and leucine-rich repeat, stimulates adipocyte differentiation. J. Biol. Chem. 279: 34840-34848.
    • (2004) J. Biol. Chem , vol.279 , pp. 34840-34848
    • Tominaga, K.1    Kondo, C.2    Kagata, T.3    Hishida, T.4    Nishizuka, M.5    Imagawa, M.6
  • 39
    • 0033597338 scopus 로고    scopus 로고
    • Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions
    • Topham, M. K., and S. M. Prescott. 1999. Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions. J. Biol. Chem. 274: 11447-11450.
    • (1999) J. Biol. Chem , vol.274 , pp. 11447-11450
    • Topham, M.K.1    Prescott, S.M.2
  • 40
    • 0025336992 scopus 로고
    • Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function
    • Paigen, B., P. A. Holmes, E. K. Novak, and R. T. Swank. 1990. Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function. Arteriosclerosis. 10: 648-652.
    • (1990) Arteriosclerosis , vol.10 , pp. 648-652
    • Paigen, B.1    Holmes, P.A.2    Novak, E.K.3    Swank, R.T.4
  • 42
    • 0033180425 scopus 로고    scopus 로고
    • Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: Functional and evolutionary aspects
    • Pan, Y., W. K. Decker, A. H. Huq, and W. J. Craigen. 1999. Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects. Genomics. 59: 282-290.
    • (1999) Genomics , vol.59 , pp. 282-290
    • Pan, Y.1    Decker, W.K.2    Huq, A.H.3    Craigen, W.J.4
  • 44
    • 0034730532 scopus 로고    scopus 로고
    • The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1
    • Miyazaki, M., Y. C. Kim, M. P. Gray-Keller, A. D. Attie, and J. M. Ntambi. 2000. The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. J. Biol. Chem. 275: 30132-30138.
    • (2000) J. Biol. Chem , vol.275 , pp. 30132-30138
    • Miyazaki, M.1    Kim, Y.C.2    Gray-Keller, M.P.3    Attie, A.D.4    Ntambi, J.M.5
  • 48
    • 0030893854 scopus 로고    scopus 로고
    • Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism
    • Machleder, D., B. Ivandic, C. Welch, L. Castellani, K. Reue, and A. J. Lusis. 1997. Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism. J. Clin. Invest. 99: 1406-1419.
    • (1997) J. Clin. Invest , vol.99 , pp. 1406-1419
    • Machleder, D.1    Ivandic, B.2    Welch, C.3    Castellani, L.4    Reue, K.5    Lusis, A.J.6
  • 50
    • 0032807348 scopus 로고    scopus 로고
    • Forte, T. M., M. N. Oda, L. Knoff, B. Frei, J. Suh, J. A. Harmony, W. D. Stuart, E. M. Rubin, and D. S. Ng. 1999. Targeted disruption of the murine lecithin:cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration. J. Lipid Res. 40: 1276-1283.
    • Forte, T. M., M. N. Oda, L. Knoff, B. Frei, J. Suh, J. A. Harmony, W. D. Stuart, E. M. Rubin, and D. S. Ng. 1999. Targeted disruption of the murine lecithin:cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration. J. Lipid Res. 40: 1276-1283.
  • 51
    • 0024399652 scopus 로고
    • The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities
    • Langner, C. A., E. H. Birkenmeier, O. Ben-Zeev, M. C. Schotz, H. O. Sweet, M. T. Davisson, and J. I. Gordon. 1989. The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities. J. Biol. Chem. 264: 7994-8003.
    • (1989) J. Biol. Chem , vol.264 , pp. 7994-8003
    • Langner, C.A.1    Birkenmeier, E.H.2    Ben-Zeev, O.3    Schotz, M.C.4    Sweet, H.O.5    Davisson, M.T.6    Gordon, J.I.7
  • 52
    • 25444465996 scopus 로고    scopus 로고
    • Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis
    • Peterfy, M., J. Phan, and K. Reue. 2005. Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis. J. Biol. Chem. 280: 32883-32889.
    • (2005) J. Biol. Chem , vol.280 , pp. 32883-32889
    • Peterfy, M.1    Phan, J.2    Reue, K.3
  • 53
    • 18044393847 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor agonists modulate heart function in transgenic mice with lipotoxic cardiomyopathy
    • Vikramadithyan, R. K., K. Hirata, H. Yagyu, Y. Hu, A. Augustus, S. Homma, and I. J. Goldberg. 2005. Peroxisome proliferator-activated receptor agonists modulate heart function in transgenic mice with lipotoxic cardiomyopathy. J. Pharmacol. Exp. Ther. 313: 586-593.
    • (2005) J. Pharmacol. Exp. Ther , vol.313 , pp. 586-593
    • Vikramadithyan, R.K.1    Hirata, K.2    Yagyu, H.3    Hu, Y.4    Augustus, A.5    Homma, S.6    Goldberg, I.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.