Scleroglucan/borax: Characterization of a novel hydrogel system suitable for drug delivery

Biomaterials

Volumn 24, Issue 16, 2003, Pages 2789-2798

  Coviello, T ^a   Grassi, M ^b   Lapasin, R ^b   Marino, A ^a   Alhaique, F ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Borax; Hydrogel; Modified release; Physically crosslinked gels; Scleroglucan

Indexed keywords

CROSSLINKING; DRUG DOSAGE; REACTION KINETICS; SWELLING;

DRUG DELIVERY;

HYDROGELS;

BORATE SODIUM; HYDROCHLORIC ACID; SCLEROGLUCAN; THEOPHYLLINE; WATER;

ACCURACY; ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG PENETRATION; DRUG SOLUBILITY; EXPERIMENTAL MODEL; GEL; HYDROGEL; KINETICS; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; TABLET MANUFACTURE; WATER TRANSPORT;

EID: 0344519686     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(03)00087-5     Document Type: Article

References (37)

1. Hoffman A.S. Hydrogels for biomedical applications. Adv Drug Delivery Rev. 43:2002;3-12.
2. Peppas N.A., Bures P., Leobandung W., Ichikawa H. Hydrogels in pharmaceutical formulations. Eur J Pharm Biopharm. 50:2000;27-46.
3. Kikuchi A., Okano T. Pulsatile drug release control using hydrogels. Adv Drug Delivery Rev. 43:2002;53-77.
4. Giavasis I., Harvey L.M., McNeil B. Scleroglucan. De Baets S., Vandamme E.J., Steinbüchel A. Biopolymers, polysaccharides II. vol. 6:2002;37-60 Wiley-VCH, Weinheim.
5. Touitou E., Alhaique F., Riccieri F.M., Riccioni G., Santucci E. Scleroglucan sustained release oral preparations. Part I. In vitro experiments. Drug Des Delivery. 5:1989;141-148.
6. Alhaique F., Carafa M., Riccieri F.M., Santucci E., Touitou E. Studies on the release behaviour of a polysaccharide matrix. Pharmazie. 48:1993;432-435.
7. Rizk S., Duru C., Gaudy D., Jacob M., Ferrari F., Bertoni M., Caramella C. Physicochemical characterization and tableting properties of Scleroglucan. Int J Pharm. 112:1994;125-131.
8. Alhaique F., Beltrami E., Riccieri F.M., Santucci E., Touitou E. Scleroglucan sustained release oral preparations Part II. Effects of additives. Drug Des Delivery. 5:1990;249-257.
9. Alhaique F., Carafa M., Coviello T., Murtas E., Riccieri F.M., Santucci E. Release from a polysaccharide matrix. effect of the molecular weight of the drug Acta Technol Legis Med. 4:1993;21-30.
10. Romanelli L., Alhaique F., Riccieri F.M., Santucci E., Valeri P. Investigation of the features of scleroglucan a polysaccharide of fungin origin as a vehicle for ocular topical administration. Pharmacol Res. 27(Suppl 1):1993;127-128.
11. Alhaique F., Riccieri F.M., Santucci E., Crescenzi V., Gamini A. A possible pH-modified drug delivery system based on a derivative of the polysaccharide scleroglucan. J Pharm Pharmacol. 37:1985;310-313.
12. Alhaique F., Riccieri F.M., Santucci E., Carafa M. Environmental effects on the delivery of drugs from a pH-sensitive matrix. Acta Technol Legis Med. 1:1990;1-9.
13. Coviello T., Maeda H., Yuguchi Y., Urakawa H., Kajiwara K., Dentini M., Crescenzi V. Conformational characteristics of oxidized scleroglucan. Macromolecules. 31:1998;1602-1607.
14. Coviello T., Dentini M., Rambone G., Desideri P., Carafa M., Murtas E., Riccieri F.M., Alhaique F. A novel co-crosslinked polysaccharide. studies for a controlled delivery matrix J Control Release. 55:1998;57-66.
15. Maeda H., Coviello T., Yuguchi Y., Urakawa H., Rambone G., Alhaique F., Kajiwara K. Structural characteristics of oxidized scleroglucan and its network. Polym Gels Networks. 6:1998;355-366.
16. Coviello T., Grassi M., Rambone G., Santucci E., Carafa M., Murtas E., Riccieri F.M., Alhaique F. Novel hydrogel system from scleroglucan. synthesis and characterization J Control Release. 60:1999;367-378.
17. Coviello T., Grassi M., Rambone G., Alhaique F. A crosslinked system from scleroglucan derivative. preparation and characterization Biomaterials. 22:2001;1899-1909.
18. Maeda H., Rambone G., Coviello T., Yuguchi Y., Urakawa H., Alhaique F., Kajiwara K. Low-Degree oxidized scleroglucan and its hydrogel. Int J Biol Macromol. 28:2001;351-358.
19. Alhaique F., Casadei M.A., Coviello T., Micheletti Moracci F. Chemical gels of scleroglucan for controlled release formulations. Acta Technol Legis Med. 12:2001;185-190.
20. Deuel H., Neukom H., Weber F. Reaction of boric acid with polysaccharides. Nature. 161:1948;96-97.
21. Davis H.B., Mott C.J.B. Interaction of boric acid and borates with carbohydrates and related substances. J Chem Soc Faraday I. 76:1980;1991-2002.
22. Cheng A.T.Y., Rodriguez F. Mechanical properties of borate crosslinked poly(vinyl alcohol) Gels. J Appl Polym Sci. 26:1981;3895-3908.
23. Ochiai H., Shimizu S., Tadokoro Y., Murakami I. Complex formation between poly(vinyl alcohol) and borate ion. Polym Commun. 22:1981;1456-1458.
24. Wing R.E., Maiti S., Doane W.M. Factors affecting release of butylate from calcium ion-modiefied starch-borate matrices. J Control Release. 5:1987;79-89.
25. Verchere J.F., Hlaibi M. Stability constants of borate complexes of oligosaccharides. Polyhedron. 6:1987;1415-1420.
26. Shibayama M., Yoshizawa H., Kurokawa H., Fujiwara H., Nomura S. Sol-gel transition of poly(vinyl alcohol)-borate complex. Polymer. 29:1988;2066-2071.
27. 11B n.m.r. study on the reaction of poly(vinylalcohol) with boric acid. Polymer. 29:1988;336-340.
28. Pezron E., Leibler L., Lafuma F. Complex formation in polymer-ion solutions. 2. Polyelectrolyte effects. Macromolecules. 22:1989;2656-2662.
29. 13C NMR spectroscopy. Carbohydr Res. 253:1994;1-12.
30. Jasinski R., Redwine D., Rose G. Boron equilibria with high molecular weight Guar. an nmr study J Polym Sci: Part B: Polym Phys. 34:1996;1477-1488.
31. 2O. killing slime J Chem Educ. 74:1997;97-99.
32. Rubinstein A., Gliko-Kabir I. Synthesis and swelling-dependent enzymatic degradation of borax-modified guar gum for colonic delivery purposes. STP Pharma Sci. 5:1995;41-46.
33. Dokoumetzidis A., Macheras P. A population growth model of dissolution. Pharm Res. 14:1997;1122-1126.
34. Dubois M., Gilles K.A., Hamilton J.K., Rebers P.A., Smith F. Colorimetric method for determination of sugars and related substances. Anal Chem. 28:1956;350-356.
35. Westrin B.A., Axelsson A., Zacchi G. Diffusion measurements in gels. J Control Release. 30:1994;189-199.
36. Patankar S.V. Numerical heat transfer and fluid flow. 1990;McGraw-Hill/Hemisphere Publishing Corporation, New York.
37. Crank J. Diffusion in a sphere. In: The mathematics of diffusion. 2nd ed. Oxford: Clarendon Press, 1975. p. 89-103 [chapter 6].