Characterization of human breast cancer epithelial cells (HBCEC) derived from long term cultured biopsies

Journal of Experimental and Clinical Cancer Research

Volumn 28, Issue 1, 2009, Pages

  Hass, Ralf ^a   Bertram, Catharina ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CD24 ANTIGEN; CYTOKERATIN; FLUORESCEIN; HERMES ANTIGEN; MUCIN 1; TELOMERASE; ANTINEOPLASTIC AGENT; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CELL CULTURE; CELL DIVISION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; TUMOR BIOPSY; AGED; BIOPSY; BREAST TUMOR; CELL AGING; CULTURE TECHNIQUE; DRUG EFFECT; EPITHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; METHODOLOGY; MIDDLE AGED; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; ULTRASTRUCTURE;

AGED; ANTINEOPLASTIC AGENTS; BIOPSY; BREAST NEOPLASMS; CELL AGING; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; TELOMERASE; TUMOR MARKERS, BIOLOGICAL;

EID: 70350369677     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-28-127     Document Type: Article

References (38)

1. Intracellular flow cytometric analysis of primary cultured breast tumor cells. RL Loveday V Speirs PJ Drew MJ Kerin JR Monson J Greenman, Cancer Invest 2002 20 340 347 10.1081/CNV-120001179 12025229
2. MMP-7 is involved in the aging of primary human mammary epithelial cells (HMEC). C Bertram R Hass, Exp Gerontol 2008 43 209 217 10.1016/j.exger.2007.11. 007 18207346
3. Isolation and growth of human mammary epithelial cells. MR Stampfer, J Tissue Culture Methods 1985 9 107 115 10.1007/BF01797781 (Pubitemid 16207734)
4. Culture of normal and malignant primary human mammary epithelial cells in a physiological manner simulates in vivo growth patterns and allows discrimination of cell type. LM Bergstraesser SA Weitzman, Cancer Res 1993 53 2644 2654 8495428
5. Selective growth of freshly isolated human breast epithelial cells cultured at low concentrations in the presence or absence of bone marrow cells. JT Emerman J Stingl A Petersen EJ Shpall CJ Eaves, Breast Cancer Res Treat 1996 41 147 159 10.1007/BF01807160 8944333
6. Novel cell culture models for prevention of human breast cancer (Review). M Katdare MP Osborne NT Telang, Int J Oncol 2003 22 509 515 12579302
7. Short-term primary culture of epithelial cells derived from human breast tumours. V Speirs AR Green DS Walton MJ Kerin JN Fox PJ Carleton SB Desai SL Atkin, Br J Cancer 1998 78 1421 1429 9836473
8. Routine culturing of normal, dysplastic and malignant human mammary epithelial cells from small tissue samples. JT Emerman DA Wilkinson, In Vitro Cell Dev Biol 1990 26 1186 1194 10.1007/BF02623697 2079464
9. Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium. J Taylor-Papadimitriou M Stampfer J Bartek A Lewis M Boshell EB Lane IM Leigh, J Cell Sci 1989 94 Pt 3 403 413 2483723
10. Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia. G Dontu MS Wicha, J Mammary Gland Biol Neoplasia 2005 10 75 86 10.1007/s10911-005-2542-5 15886888
11. Stem cells and breast cancer: A field in transit. M Smalley A Ashworth, Nat Rev Cancer 2003 3 832 844 10.1038/nrc1212 14668814
12. Stem cells in normal breast development and breast cancer. G Dontu M Al-Hajj WM Abdallah MF Clarke MS Wicha, Cell Prolif 2003 36 Suppl 1 59 72 10.1046/j.1365-2184.36.s.1.6.x 14521516 (Pubitemid 37521844)
13. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. G Dontu WM Abdallah JM Foley KW Jackson MF Clarke MJ Kawamura MS Wicha, Genes Dev 2003 17 1253 1270 10.1101/gad.1061803 12756227
14. Evidence for the isolation, growth, and characterization of malignant cells in primary cultures of human tumors. RL Ochs J Fensterer NP Ohori A Wells M Gabrin LD George P Kornblith, In Vitro Cell Dev Biol Anim 2003 39 63 70 10.1290/1543-706X(2003)039<0063:EFTIGA2.0.CO;2 12892529
15. New concepts regarding focal adhesion kinase promotion of cell migration and proliferation. BD Cox M Natarajan MR Stettner CL Gladson, J Cell Biochem 2006 99 35 52 10.1002/jcb.20956 16823799
16. Can cancer be reversed by engineering the tumor microenvironment? DE Ingber, Semin Cancer Biol 2008 18 356 364 10.1016/j.semcancer.2008.03.016 18472275
17. Cadherins and the mammary gland. KA Knudsen MJ Wheelock, J Cell Biochem 2005 95 488 496 10.1002/jcb.20419 15838893
18. Adhesion systems in normal breast and in invasive breast carcinoma. M Glukhova V Koteliansky X Sastre JP Thiery, Am J Pathol 1995 146 706 716 7887451
19. Dedifferentiation of human hepatocytes by extracellular matrix proteins in vitro: quantitative and qualitative investigation of cytokeratin 7, 8, 18, 19 and vimentin filaments. RA Blaheta B Kronenberger D Woitaschek MK Auth M Scholz S Weber H Schuldes A Encke BH Markus, J Hepatol 1998 28 677 690 10.1016/S0168-8278(98)80293-6 9566838
20. Altered expression of keratin and vimentin in human retinal pigment epithelial cells in vivo and in vitro. RC Hunt AA Davis, J Cell Physiol 1990 145 187 199 10.1002/jcp.1041450202 1700982
21. Simultaneous expression of two different types of intermediate sized filaments in mouse keratinocytes proliferating in vitro. WW Franke E Schmid D Breitkreutz M Luder P Boukamp NE Fusenig M Osborn K Weber, Differentiation 1979 14 35 50 10.1111/j.1432-0436.1979.tb01010.x 383562
22. Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells. I Brockhausen JM Yang J Burchell C Whitehouse J Taylor-Papadimitriou, Eur J Biochem 1995 233 607 617 10.1111/j.1432-1033.1995. 607-2.x 7588808
23. MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation. JA Schroeder AA Masri MC Adriance JC Tessier KL Kotlarczyk MC Thompson SJ Gendler, Oncogene 2004 23 5739 5747 10.1038/sj.onc.1207713 15221004
24. Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene. X Wei H Xu D Kufe, Cancer Res 2007 67 1853 1858 10.1158/0008-5472.CAN-06-3063 17308127
25. Epithelial progenitors in the normal human mammary gland. J Stingl A Raouf JT Emerman CJ Eaves, J Mammary Gland Biol Neoplasia 2005 10 49 59 10.1007/s10911-005-2540-7 15886886
26. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. KE Sleeman H Kendrick A Ashworth CM Isacke MJ Smalley, Breast Cancer Res 2006 8 7 10.1186/bcr1371 16417656
27. CD24 expression in ductal carcinoma in situ and invasive ductal carcinoma of breast: an immunohistochemistry-based pilot study. S Bircan N Kapucuoglu S Baspinar G Inan O Candir, Pathol Res Pract 2006 202 569 576 10.1016/j.prp.2006. 05.004 16828238
28. CD24 and human carcinoma: tumor biological aspects. SC Lim, Biomed Pharmacother 2005 59 Suppl 2 351 354 10.1016/S0753-3322(05)80076-9 16507407
29. CD44 and its interaction with extracellular matrix. J Lesley R Hyman PW Kincade, Adv Immunol 1993 54 271 335 full-text 8379464
30. The prognostic role of a gene signature from tumorigenic breast-cancer cells. R Liu X Wang GY Chen P Dalerba A Gurney T Hoey G Sherlock J Lewicki K Shedden MF Clarke, N Engl J Med 2007 356 217 226 10.1056/NEJMoa063994 17229949
31. Prospective identification of tumorigenic breast cancer cells. M Al-Hajj MS Wicha A Benito-Hernandez SJ Morrison MF Clarke, Proc Natl Acad Sci USA 2003 100 3983 3988 10.1073/pnas.0530291100 12629218 (Pubitemid 36418143)
32. Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man? C Fillmore C Kuperwasser, Breast Cancer Res 2007 9 303 10.1186/bcr1673 17540049
33. MMP-7 is involved in the aging of primary human mammary epithelial cells (HMEC). C Bertram R Hass, Exp Gerontol 2008 43 209 217 10.1016/j.exger.2007.11. 007 18207346
34. Telomerase in cancer and aging. MP Granger WE Wright JW Shay, Crit Rev Oncol Hematol 2002 41 29 40 10.1016/S1040-8428(01)00188-3 11796230
35. Prognostic significance of reactivation of telomerase in breast core biopsy specimens. GS Herbert VY Sohn MJ Mulcahy AL Champeaux TA Brown, Am J Surg 2007 193 547 550 discussion 550 10.1016/j.amjsurg.2007.01.011 17434352
36. Clinical studies with epothilones for the treatment of metastatic breast cancer. LT Vahdat, Semin Oncol 2008 35 22 30 quiz S40 10.1053/j.seminoncol.2008. 02.003 18410796
37. Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel. TC Chou XG Zhang CR Harris SD Kuduk A Balog KA Savin JR Bertino SJ Danishefsky, Proc Natl Acad Sci USA 1998 95 15798 15802 10.1073/pnas.95.26.15798 9861050
38. Epothilones: a novel class of microtubule-stabilizing drugs for the treatment of cancer. M Trivedi I Budihardjo K Loureiro TR Reid JD Ma, Future Oncol 2008 4 483 500 10.2217/14796694.4.4.483 18684060