메뉴 건너뛰기




Volumn 22, Issue 4, 2009, Pages 953-961

Human HSP70 and modified HPV16 E7 fusion DNA vaccine induces enhanced specific CD8+ T cell responses and anti-tumor effects

Author keywords

Cervical cancer; DNA vaccine; E7 gene; Heat shock protein 70; Human papilloma virus 16

Indexed keywords

DNA VACCINE; HEAT SHOCK PROTEIN 70; PROTEIN E7;

EID: 70350359428     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000522     Document Type: Article
Times cited : (32)

References (45)
  • 1
    • 0037434411 scopus 로고    scopus 로고
    • Human papillomavirus types in invasive cervical cancer worldwide: A meta-analysis
    • Clifford GM, Smith JS, Plummer M, Munoz N and Franceschi S: Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis. Br J Cancer 88: 63-73, 2003.
    • (2003) Br J Cancer , vol.88 , pp. 63-73
    • Clifford, G.M.1    Smith, J.S.2    Plummer, M.3    Munoz, N.4    Franceschi, S.5
  • 2
    • 3142661757 scopus 로고    scopus 로고
    • Against which human papillomavirus types shall we vaccinate and screen? The international perspective
    • Muñoz N, Bosch FX, Castellsagué X, et al: Against which human papillomavirus types shall we vaccinate and screen? The international perspective. Int J Cancer 111: 278-285, 2004.
    • (2004) Int J Cancer , vol.111 , pp. 278-285
    • Muñoz, N.1    Bosch, F.X.2    Castellsagué, X.3
  • 3
    • 31944448352 scopus 로고    scopus 로고
    • Associations of high-risk HPV types and viral load with cervical cancer in China
    • Wu Y, Chen Y, Li L, Yu G, Zhang Y and He Y: Associations of high-risk HPV types and viral load with cervical cancer in China. J Clin Virol 35: 264-269, 2006.
    • (2006) J Clin Virol , vol.35 , pp. 264-269
    • Wu, Y.1    Chen, Y.2    Li, L.3    Yu, G.4    Zhang, Y.5    He, Y.6
  • 4
    • 39049187522 scopus 로고    scopus 로고
    • Siddiqui MA and Perry CM: Human papillomavirus quadrivalent (types 6, 11, 16, 18) recombinant vaccine (Gardasil): profile report. BioDrugs 20: 313-316, 2006.
    • Siddiqui MA and Perry CM: Human papillomavirus quadrivalent (types 6, 11, 16, 18) recombinant vaccine (Gardasil): profile report. BioDrugs 20: 313-316, 2006.
  • 5
    • 33847701587 scopus 로고    scopus 로고
    • Cervarix - a bivalent L1 virus-like particle vaccine for prevention of human papillomavirus type 16- and 18-associated cervical cancer
    • Crosbie EJ and Kitchener HC: Cervarix - a bivalent L1 virus-like particle vaccine for prevention of human papillomavirus type 16- and 18-associated cervical cancer. Expert Opin Biol Ther 7: 391-396, 2007.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 391-396
    • Crosbie, E.J.1    Kitchener, H.C.2
  • 6
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • Hausen H: Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2: 342-350, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 342-350
    • Hausen, H.1
  • 7
    • 0032519813 scopus 로고    scopus 로고
    • Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype
    • Zehbe I, Wilander E, Delius H and Tommasino M: Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype. Cancer Res 58: 829-833, 1998.
    • (1998) Cancer Res , vol.58 , pp. 829-833
    • Zehbe, I.1    Wilander, E.2    Delius, H.3    Tommasino, M.4
  • 8
    • 0034046182 scopus 로고    scopus 로고
    • DNA vaccines: Immunology, application, and optimization
    • Gurunathan S, Klinman DM and Seder RA: DNA vaccines: immunology, application, and optimization. Annu Rev Immunol 18: 927-974, 2000.
    • (2000) Annu Rev Immunol , vol.18 , pp. 927-974
    • Gurunathan, S.1    Klinman, D.M.2    Seder, R.A.3
  • 10
    • 0036467388 scopus 로고    scopus 로고
    • Roles of heat-shock proteins in antigen presentation and cross-presentation
    • Li Z, Menoret A and Srivastava P: Roles of heat-shock proteins in antigen presentation and cross-presentation. Curr Opin Immunol 14: 45-51, 2002.
    • (2002) Curr Opin Immunol , vol.14 , pp. 45-51
    • Li, Z.1    Menoret, A.2    Srivastava, P.3
  • 11
    • 0036214288 scopus 로고    scopus 로고
    • Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses
    • Srivastava P: Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu Rev Immunol 20: 395-425, 2002.
    • (2002) Annu Rev Immunol , vol.20 , pp. 395-425
    • Srivastava, P.1
  • 12
    • 0034113617 scopus 로고    scopus 로고
    • HSP70 stimulates cytokine production through a CD14-dependent pathway, demonstrating its dual role as a chaperone and cytokine
    • Asea A, Kraeft SK, Kurt-Jones EA, et al: HSP70 stimulates cytokine production through a CD14-dependent pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med 6: 435-442, 2000.
    • (2000) Nat Med , vol.6 , pp. 435-442
    • Asea, A.1    Kraeft, S.K.2    Kurt-Jones, E.A.3
  • 14
    • 0035007710 scopus 로고    scopus 로고
    • The role of heat shock protein (hsp70) in dendritic cell maturation: Hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors
    • Kuppner MC, Gastpar R, Gelwer S, Nössner E, Ochmann O, Scharner A and Issels RD: The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors. Eur J Immunol 31: 1602-1609, 2001.
    • (2001) Eur J Immunol , vol.31 , pp. 1602-1609
    • Kuppner, M.C.1    Gastpar, R.2    Gelwer, S.3    Nössner, E.4    Ochmann, O.5    Scharner, A.6    Issels, R.D.7
  • 15
  • 16
    • 2942748077 scopus 로고    scopus 로고
    • Secretory heat-shock protein as a dendritic cell-targeting molecule: A new strategy to enhance the potency of genetic vaccines
    • Hauser H, Shen L, Gu QL, Krueger S and Chen SY: Secretory heat-shock protein as a dendritic cell-targeting molecule: a new strategy to enhance the potency of genetic vaccines. Gene Ther 11: 924-932, 2004.
    • (2004) Gene Ther , vol.11 , pp. 924-932
    • Hauser, H.1    Shen, L.2    Gu, Q.L.3    Krueger, S.4    Chen, S.Y.5
  • 18
    • 0033198580 scopus 로고    scopus 로고
    • Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
    • Steinhoff U, Brinkmann V, Klemm U, et al: Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells. Immunity 11: 349-358,1999.
    • (1999) Immunity , vol.11 , pp. 349-358
    • Steinhoff, U.1    Brinkmann, V.2    Klemm, U.3
  • 19
    • 0038737428 scopus 로고    scopus 로고
    • Role of heat shock proteins in protection from and pathogenesis of infectious diseases
    • Zugel U and Kaufmann SHE: Role of heat shock proteins in protection from and pathogenesis of infectious diseases. Clin Microbiol Rev 12: 19-39, 1999.
    • (1999) Clin Microbiol Rev , vol.12 , pp. 19-39
    • Zugel, U.1    Kaufmann, S.H.E.2
  • 25
    • 0035077790 scopus 로고    scopus 로고
    • Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen
    • Hsu KF, Hung CF, Cheng WF, He L, Slater LA, Ling M and Wu TC: Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen. Gene Ther 8: 376-383, 2001.
    • (2001) Gene Ther , vol.8 , pp. 376-383
    • Hsu, K.F.1    Hung, C.F.2    Cheng, W.F.3    He, L.4    Slater, L.A.5    Ling, M.6    Wu, T.C.7
  • 27
    • 0034252620 scopus 로고    scopus 로고
    • CD91: A receptor for heat shock protein gp96
    • Binder RJ, Han DK and Srivastava PK: CD91: a receptor for heat shock protein gp96. Nat Immunol 1: 151-155, 2000.
    • (2000) Nat Immunol , vol.1 , pp. 151-155
    • Binder, R.J.1    Han, D.K.2    Srivastava, P.K.3
  • 28
    • 18644364531 scopus 로고    scopus 로고
    • Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation
    • Delneste Y, Magistrelli G, Gauchat J, et al: Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity 17: 353-362, 2002.
    • (2002) Immunity , vol.17 , pp. 353-362
    • Delneste, Y.1    Magistrelli, G.2    Gauchat, J.3
  • 29
    • 0034677127 scopus 로고    scopus 로고
    • In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4 (+) T-cell independent
    • Huang Q, Richmond JF, Suzue K, Eisen HN and Young RA: In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4 (+) T-cell independent. J Exp Med 191: 403-408, 2000.
    • (2000) J Exp Med , vol.191 , pp. 403-408
    • Huang, Q.1    Richmond, J.F.2    Suzue, K.3    Eisen, H.N.4    Young, R.A.5
  • 31
    • 0026525090 scopus 로고
    • The use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guérin priming
    • Barrios C, Lussow AR, Van Embden J, et al: The use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guérin priming. Eur J Immunol 22: 1365-1372, 1992.
    • (1992) Eur J Immunol , vol.22 , pp. 1365-1372
    • Barrios, C.1    Lussow, A.R.2    Van Embden, J.3
  • 32
    • 0030028801 scopus 로고    scopus 로고
    • Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24
    • Suzue K and Young RA: Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24. J Immunol 156: 873-876, 1996.
    • (1996) J Immunol , vol.156 , pp. 873-876
    • Suzue, K.1    Young, R.A.2
  • 33
    • 26044433779 scopus 로고    scopus 로고
    • Message in a bottle: Role of the 70-kDa heat shock protein family in anti-tumor immunity
    • Calderwood SK, Theriault JR and Gong J: Message in a bottle: role of the 70-kDa heat shock protein family in anti-tumor immunity. Eur J Immunol 35: 2518-2527, 2005.
    • (2005) Eur J Immunol , vol.35 , pp. 2518-2527
    • Calderwood, S.K.1    Theriault, J.R.2    Gong, J.3
  • 34
    • 17844398281 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis heat shock fusion protein enhances class I MHC cross-processing and - presentation by B lymphocytes
    • Tobian AA, Harding CV and Canaday DH: Mycobacterium tuberculosis heat shock fusion protein enhances class I MHC cross-processing and - presentation by B lymphocytes. J Immunol 174: 5209-5214, 2005.
    • (2005) J Immunol , vol.174 , pp. 5209-5214
    • Tobian, A.A.1    Harding, C.V.2    Canaday, D.H.3
  • 35
    • 33744522260 scopus 로고    scopus 로고
    • Generation of anti-tumor immunity using mammalian heat shock protein 70 DNA vaccines for cancer immunotherapy
    • Li Y, Subjeck J, Yang G, Repasky E and Wang XY: Generation of anti-tumor immunity using mammalian heat shock protein 70 DNA vaccines for cancer immunotherapy. Vaccine 24: 5360-5370, 2006.
    • (2006) Vaccine , vol.24 , pp. 5360-5370
    • Li, Y.1    Subjeck, J.2    Yang, G.3    Repasky, E.4    Wang, X.Y.5
  • 36
    • 0037435923 scopus 로고    scopus 로고
    • Immunopotentiating heat shock proteins: Negotiators between innate danger and control of autoimmunity
    • Van Eden W, Koets A, van Kooten P, Prakken B and van der Zee R: Immunopotentiating heat shock proteins: negotiators between innate danger and control of autoimmunity. Vaccine 21: 897-901, 2003.
    • (2003) Vaccine , vol.21 , pp. 897-901
    • Van Eden, W.1    Koets, A.2    van Kooten, P.3    Prakken, B.4    van der Zee, R.5
  • 37
    • 0141885424 scopus 로고    scopus 로고
    • Innate immune responses to mycobacteria and the downregulation of atopic responses
    • Rook GA, Martinelli R and Brunet LR: Innate immune responses to mycobacteria and the downregulation of atopic responses. Curr Opin Allergy Clin Immunol 3: 337-342, 2003.
    • (2003) Curr Opin Allergy Clin Immunol , vol.3 , pp. 337-342
    • Rook, G.A.1    Martinelli, R.2    Brunet, L.R.3
  • 39
    • 0028279059 scopus 로고
    • DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1
    • Lukas J, Müller H, Bartkova J, et al: DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1. J Cell Biol 125: 625-638, 1994.
    • (1994) J Cell Biol , vol.125 , pp. 625-638
    • Lukas, J.1    Müller, H.2    Bartkova, J.3
  • 40
    • 0035919589 scopus 로고    scopus 로고
    • A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16) induces E7-specific cytotoxic T cells but lacks transforming activity
    • Osen W, Peiler T, Ohlschlager P, et al: A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16) induces E7-specific cytotoxic T cells but lacks transforming activity. Vaccine 19: 4276-4286, 2001.
    • (2001) Vaccine , vol.19 , pp. 4276-4286
    • Osen, W.1    Peiler, T.2    Ohlschlager, P.3
  • 41
    • 0032838682 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 DNA vaccine: Mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity
    • Shi W, Bu P, Liu J, Polack A, Fisher S and Qiao L: Human papillomavirus type 16 E7 DNA vaccine: mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity. J Virol 73: 7877-7881, 1999.
    • (1999) J Virol , vol.73 , pp. 7877-7881
    • Shi, W.1    Bu, P.2    Liu, J.3    Polack, A.4    Fisher, S.5    Qiao, L.6
  • 42
    • 0035866607 scopus 로고    scopus 로고
    • Modified HPV16 E7 genes as DNA vaccine against E7-containing oncogenic cells
    • Smahel M, Sima P, Ludvikova V and Vonka V: Modified HPV16 E7 genes as DNA vaccine against E7-containing oncogenic cells. Virology 281: 231-238, 2001.
    • (2001) Virology , vol.281 , pp. 231-238
    • Smahel, M.1    Sima, P.2    Ludvikova, V.3    Vonka, V.4
  • 43
    • 0036396551 scopus 로고    scopus 로고
    • Codon modified human papillomavirus type 16 E7 DNA vaccine enhances cytotoxic T-lymphocyte induction and anti-tumour activity
    • Liu WJ, Gao F, Zhao KN, Zhao W, Fernando GJ, Thomas R and Frazer IH: Codon modified human papillomavirus type 16 E7 DNA vaccine enhances cytotoxic T-lymphocyte induction and anti-tumour activity. Virology 301: 43-52, 2002.
    • (2002) Virology , vol.301 , pp. 43-52
    • Liu, W.J.1    Gao, F.2    Zhao, K.N.3    Zhao, W.4    Fernando, G.J.5    Thomas, R.6    Frazer, I.H.7
  • 44
    • 0025247797 scopus 로고
    • Stress proteins and immunology
    • Young RA: Stress proteins and immunology. Annu Rev Immunol 8: 401-420, 1990.
    • (1990) Annu Rev Immunol , vol.8 , pp. 401-420
    • Young, R.A.1
  • 45
    • 0025358777 scopus 로고
    • Autoimmune diseases: The failure of self tolerance
    • Sinha AA, Lopez M and McDevitt HO: Autoimmune diseases: the failure of self tolerance. Science 248: 1380-1388, 1990.
    • (1990) Science , vol.248 , pp. 1380-1388
    • Sinha, A.A.1    Lopez, M.2    McDevitt, H.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.