Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity

Life Sciences

Volumn 85, Issue 19-20, 2009, Pages 711-718

  Kumar, Puneet ^a   Kalonia, Harikesh ^a   Kumar, Anil ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

3 Nitropropionic acid; Basal ganglia; Lycopene; Mitochondria; Nitric oxide; Oxidative stress

Indexed keywords

3 NITROPROPIONIC ACID; ARGININE; CATALASE; CYTOCHROME C OXIDASE; LYCOPENE; MALONALDEHYDE; MITOCHONDRIAL ENZYME; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BODY WEIGHT; BRAIN CORTEX; BRAIN LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INACTIVATION; HIPPOCAMPUS; HUNTINGTON DISEASE LIKE SYNDROME; LIPID PEROXIDATION; LOCOMOTION; MALE; MOTOR COORDINATION; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RAT; ROTAROD TEST;

ANIMALS; ANTICARCINOGENIC AGENTS; BODY WEIGHT; CAROTENOIDS; CATALASE; COLORING AGENTS; ELECTRON TRANSPORT COMPLEX IV; HUNTINGTON DISEASE; LIPID PEROXIDATION; MALE; MOTOR ACTIVITY; NADH DEHYDROGENASE; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; NEUROTOXINS; NITRIC OXIDE; NITRITES; NITRO COMPOUNDS; OXIDATIVE STRESS; PROPIONIC ACIDS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; TETRAZOLIUM SALTS; THIAZOLES;

ANIMALIA; RATTUS;

EID: 70350307195     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.10.001     Document Type: Article

References (46)

1. Akula K.K., Dhir A., and Kulkarni S.K. Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice. European Journal of Pharmacology 587 (2008) 129-134
2. Akbaraly N.T., Faure H., Gourlet V., Favier A., and Berr C. Plasma carotenoid levels and cognitive performance in an elderly population: results of the EVA Study. Journal of Gerontology and Biological Sciences Medical Sciences 62 (2007) 308-316
3. Alexi T., Hughes P.E., Faull R.L., and Williams C.E. 3-Nitropropionic acid's lethal triplet: cooperative pathways of neurodegeneration. NeuroReport 9 (1998) R57-R64
4. Alston T.A., Mela L., and Bright H.J. 3-Nitropropionate, the toxic substance of Indigofera, is a suicide inactivator of succinate dehydrogenase. Proceedings of the National Academy of Sciences U S A 74 (1977) 3767-3771
5. Atessahin A., Ceribasi A.O., and Yilmaz S. Lycopene, a carotenoid, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rats. Basic and Clinical Pharmacology Toxicology 100 (2007) 372-376
6. Atessahin A., Yilmaz S., Karahan I., Ceribasi A.O., and Karaoglu A. Effects of lycopene against cisplatin-induced nephrotoxicity and oxidative stress in rats. Toxicology 212 (2005) 116-123
7. Beal M.F., Brouillet E., Jenkins B.G., Ferrante R.J., Kowall N.W., Miller J.M., Storey E., Srivastava R., Rosen B.R., and Hyman B.T. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. Journal of Neuroscience 13 (1993) 4181-4192
8. Beckman J.S. Oxidative damage and tyrosine nitration from peroxynitrite. Chemical Research in Toxicology 9 (1996) 836-844
9. Berman S.B., and Hastings T.G. Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease. Journal of Neurochemistry 73 (1999) 1127-1137
10. Blum D., Gall D., Cuvelier L., and Schiffmann S.N. Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat. NeuroReport 12 (2001) 1769-1772
11. Borlongan C.V., Koutouzis T.K., and Sanberg P.R. 3-Nitropropionic acid animal model and Huntington's disease. Neuroscience Biobehaviour Reviews 21 (1997) 289-293
12. Brouillet E., Conde F., Beal M.F., and Hantraye P. Replicating Huntington's disease phenotype in experimental animals. Progress in Neurobiology 59 (1999) 427-468
13. Browne S.E., Ferrante R.J., and Beal M.F. Oxidative stress in Huntington's disease. Brain Pathology 9 (1999) 147-163
14. Cipriani S., Bizzoco E., Gianfriddo M., Melani A., Vannucchi M.G., and Pedata F. Adenosine A2A receptor antagonism increases nNOS-immunoreactive neurons in the striatum of Huntington transgenic mice. Experimental Neurology 213 (2008) 163-170
15. Cohen L.A. A review of animal model studies of tomato carotenoids, lycopene, and cancer chemoprevention. Experimental Biology Medicine (Maywood) 227 (2002) 864-878
16. Coles C.J., Edmondson D.E., and Singer T.P. Inactivation of succinate dehydrogenase by 3-nitropropionate. Journal of Biology Chemistry 254 (1979) 5161-5167
17. Deshpande S.B., Hida H., Takei-Io N., Masuda T., Baba H., and Nishino H. Involvement of nitric oxide in 3-nitropropionic acid-induced striatal toxicity in rats. Brain Research 1108 (2006) 205-215
18. Gornall A.G., Bardawill C.J., and David M.M. Determination of serum proteins by means of the biuret reaction. Journal of Biology Chemistry 177 (1949) 751-766
19. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S., and Tannenbaum S.R. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Annals Biochemistry 126 (1982) 131-138
20. Gunasekera R.S., Sewgobind K., Desai S., Dunn L., Black H.S., McKeehan W.L., and Patil B. Lycopene and lutein inhibit proliferation in rat prostate carcinoma cells. Nutrition and Cancer 58 (2007) 171-177
21. Hsiao G., Fong T.H., Tzu N.H., Lin K.H., Chou D.S., and Sheu J.R. A potent antioxidant, lycopene, affords neuroprotection against microglia activation and focal cerebral ischemia in rats. In Vivo 18 (2004) 351-356
22. Ju T.C., Yang Y.T., and Yang D.I. Protective effects of S-nitrosoglutathione against neurotoxicity of 3-nitropropionic acid in rat. Neuroscience Letters 362 (2006) 226-231
23. Karahan I., Atessahin A., Yilmaz S., Ceribasi A.O., and Sakin F. Protective effect of lycopene on gentamicin-induced oxidative stress and nephrotoxicity in rats. Toxicology 215 (2005) 198-204
24. King T.E. Preparation of succinate dehydrogenase and reconstitution of succinate oxidase. Methods in Enzymology 10 (1967) 322-331
25. King T.E., and Howard R.L. Preparations and properties of soluble NADH dehydrogenases from cardiac muscle. Methods in Enzymology 10 (1967) 275-284
26. Kono Y. Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay of superoxide dismutase. Archives of Biochemistry and Biophysics 186 (1978) 189-195
27. Kuhad A., Sethi R., and Chopra K. Lycopene attenuates diabetes-associated cognitive decline in rats. Life Sciences 83 (2008) 128-134
28. Kumar P., and Kumar A. Prolonged pretreatment with carvedilol prevents 3-nitropropionic acid-induced behavioral alterations and oxidative stress in rats. Pharmacology Reports 60 (2008) 706-715
29. Kumar P., and Kumar A. Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain. Progress in Neuro-Psychopharmacology and Biological Psychiatry 33 (2009) 100-108
30. Kumar P., Padi S.S., Naidu P.S., and Kumar A. Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms. Behavioural Pharmacology 17 (2006) 485-492
31. Kumar P., Padi S.S., Naidu P.S., and Kumar A. Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms. Fundamental Clinical and Pharmacology 21 (2007) 297-306
32. La Fontaine M.A., Geddes J.W., Banks A., and Butterfield D.A. 3-nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: insights into Huntington's disease. Brain Research 858 (2000) 356-362
33. Lafon-Cazal M., Pietri S., Culcasi M., and Bockaert J. NMDA-dependent superoxide production and neurotoxicity. Nature 364 (1993) 535-537
34. Liu Y., Peterson D.A., Kimura H., and Schubert D. Mechanisms of cellular 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolinium bromide (MTT) reduction. Journal of Neurochemistry 69 (1997) 581-593
35. Luck H. Catalase. In: Bergmeyer H.U. (Ed). Methods of Enzymatic Analysis (1971), Academic Press, New York 885-893
36. Ludolph A.C., He F., Spencer P.S., Hammerstad J., and Sabri M. 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. Canadian Journal Neurology Sciences 18 (1991) 492-498
37. Nam E., Lee S.M., Koh S.E., Joo W.S., Maeng S., Im H.I., and Kim Y.S. Melatonin protects against neuronal damage induced by 3-nitropropionic acid in rat striatum. Brain Research 1046 (2005) 90-96
38. Nishino H., Fujimoto I., Shimano Y., Hida H., Kumazaki M., and Fukuda A. 3-Nitropropionic acid produces striatum selective lesions accompanied by iNOS expression. Journal of Chemical Neuroanatomy 10 (1996) 209-212
39. Rafi M.M., Yadav P.N., and Reyes M. Lycopene inhibits LPS-induced proinflammatory mediator inducible nitric oxide synthase in mouse macrophage cells. Journal of Food Science 72 (2007) S069-S074
40. Sottocasa G.L., Kuylenstierna B., Ernster L., and Bergstrand A. An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. Journal of Cell Bioliolgy 32 (1967) 415-438
41. Schulz J.B., Matthews R.T., Henshaw D.R., and Beal M.F. Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases. Neuroscience 71 (1996) 1043-1048
42. Tapiero H., Townsend D.M., and Tew K.D. The role of carotenoids in the prevention of human pathologies. Biomedicine Pharmacotherapy 58 (2004) 100-110
43. Tunez I., Montilla P., Del Carmen Munoz M., Feijoo M., and Salcedo M. Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington's disease. Journal of Pineal Research 37 (2004) 252-256
44. Visioli F., Riso P., Grande S., Galli C., and Porrini M. Protective activity of tomato products on in vivo markers of lipid oxidation. European Journal of Nutrition 42 (2003) 201-206
45. Wills E.D. Mechanisms of lipid peroxide formation in animal tissues. Biochemical Journal 99 (1966) 667-676
46. Yilmaz S., Atessahin A., Sahna E., Karahan I., and Ozer S. Protective effect of lycopene on adriamycin-induced cardiotoxicity and nephrotoxicity. Toxicology 218 (2006) 164-671