Cysteine protease-mediated cytoskeleton interactions with LFA-1 promote T-cell morphological changes

Cell Motility and the Cytoskeleton

Volumn 66, Issue 11, 2009, Pages 1030-1040

  Jevnikar, Zala ^a   Obermajer, Nataša ^a   Kos, Janko ^a,b  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

Cathepsin L; Cathepsin X; High affinity LFA 1; T cell morphology; Talin

Indexed keywords

ACTIN; CATHEPSIN L; CATHEPSIN X; CYSTEINE PROTEINASE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PROCATHEPSIN X; PROTEIN PRECURSOR; TALIN; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; CELL MEMBRANE; CELL SHAPE; CELL STRUCTURE; CHEMOTAXIS; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOPLASM; ENZYME INHIBITION; HUMAN; HUMAN CELL; LYMPHOCYTE MIGRATION; LYSOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE;

ACTINS; CATHEPSINS; CELL POLARITY; CELL SURFACE EXTENSIONS; CHEMOTAXIS; CYSTEINE PROTEASES; HUMANS; JURKAT CELLS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; PROTEIN MULTIMERIZATION; T-LYMPHOCYTES; TALIN;

UROPODA;

EID: 70350243049     PISSN: 08861544     EISSN: 10970169     Source Type: Journal    
DOI: 10.1002/cm.20413     Document Type: Conference Paper

References (49)

1. del Pozo MA, Sánchez-Mateos P, Nieto M, Sánchez-Madrid F. 1995. Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway. J Cell Biol 131:495-508.
2. Eddy RJ, Pierini LM, Matsumura F, Maxfield FR. 2000. Ca21-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci 113:1287-1298. (Pubitemid 30229545)
3. Friedl P, Borgmann S, Bröcker EB. 2001. Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement. J Leukoc Biol 70:491-509. (Pubitemid 32954760)
4. García-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC. 2003. Structural determinants of integrin recognition by talin. Mol Cell 11:49-58. (Pubitemid 36131107)
5. Guinec N, Dalet-Fumeron V, Pagano M. 1993. "In vitro" study of basement membrane degradation by the cysteine proteinases, cathepsins B. B-like and L. Digestion of collagen IV, laminin, fibronectin, and release of gelatinase activities from basement membrane fibronectin. Biol Chem Hoppe Seyler 374:1135-1146.
6. Hibbs ML, Xu H, Stacker SA, Springer TA. 1991. Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit. Science 251:1611-1613. (Pubitemid 21916935)
7. Hmama Z, Knutson KL, Herrera-Velit P, Nandan D, Reiner NE. 1999. Monocyte adherence induced by lipopolysaccharide involves CD14. LFA-1, and cytohesin-1. Regulation by Rho and phosphatidylinositol 3-kinase. J Biol Chem 274:1050-1057. (Pubitemid 29058079)
8. Jevnikar Z, Obermajer N, Bogyo M, Kos J. 2008. The role of cathepsin X in the migration and invasiveness of T lymphocytes. J Cell Sci 121:2652-2661.
9. Kim M, Carman CV, Springer TA. 2003. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 301:1720-1725. (Pubitemid 37174365)
10. Kolanus W, Nagel W, Schiller B, Zeitlmann L, Godar S, Stockinger H, Seed B. 1996. Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule. Cell 86:233-242.
11. Kos J, Sekirnik A, Premzl A, Zavasnik Bergant V, Langerholc T, Turk B, Werle B, Golouh R, Repnik U, Jeras M, Turk V. 2005. Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. Exp Cell Res 306(1):103-113. (Pubitemid 40692776)
12. Krueger S, Kellner U, Buehling F, Roessner A. 2001. Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotype. Cancer Gene 8:522-528.
13. Krummel MF, Macara I. 2006. Maintenance and modulation of T cell polarity. Nat Immunol 7:1143-1149.
14. Liliental J, Chang DD. 1998. Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit. J Biol Chem 273:2379-2383. (Pubitemid 28069294)
15. Lim J, Wiedemann A, Tzircotis G, Monkley SJ, Critchley DR, Caron E. 2007. An essential role for talin during alpha(M)beta(2)- mediated phagocytosis. Mol Biol Cell 18:976-985.
16. Ling K, Doughman RL, Iyer VV, Firestone AJ, Bairstow SF, Mosher DF, Schaller MD, Anderson RA. 2003. Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch. J Cell Biol 163:1339-1349. (Pubitemid 38032094)
17. Liu S, Calderwood DA, Ginsberg MH. 2000. Integrin cytoplasmic domain-binding proteins. J Cell Sci 113:3563-3571.
18. Maciewicz RA, Etherington DJ, Kos J, Turk V. 1987. Collagenolytic cathepsins of rabbit spleen: a kinetic analysis of collagen degradation and inhibition by chicken cystatin. Coll Relat Res 7:295-304.
19. Morin NA, Oakes PW, Hyun YM, Lee D, Chin YE, King MR, Springer TA, Shimaoka M, Tang JX, Reichner JS, Kim M. 2008. Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. J Exp Med 205:195-205. (Pubitemid 351185726)
20. Nägler DK, Zhang R, Tam W, Sulea T, Purisima EO, Ménard R. 1999. Human cathepsin X: a cysteine protease with unique carboxypeptidase activity. Biochemistry 38:12648-12654. (Pubitemid 129515561)
21. Nurmi SM, Autero M, Raunio AK, Gahmberg CG, Fagerholm SC. 2007. Phosphorylation of the LFA-1 integrin beta2-chain on Thr-758 leads to adhesion. Rac-1/Cdc42 activation, and stimulation of CD69 expression in human T cells. J Biol Chem 282:968-975. (Pubitemid 47076564)
22. Obermajer N, Repnik U, Jevnikar Z, Turk B, Kreft M, Kos J. 2008a. Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins. Immunology 124:76-88.
23. Obermajer N, Svajger U, Bogyo M, Jeras M, Kos J. 2008b. Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X. J Leukoc Biol 84:1306-1315.
24. Pavalko FM, Burridge K. 1991. Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin. J Cell Biol 114:481-491. (Pubitemid 21909817)
25. Pierini LM, Lawson MA, Eddy RJ, Hendey B, Maxfield FR. 2000. Oriented endocytic recycling of alpha5beta1 in motile neutrophils. Blood 95:2471-2480.
26. Pollard TD, Borisy GG. 2003. Cellular motility driven by assembly and disassembly of actin filaments. Cell 112:453-465.
27. Porter JC, Bracke M, Smith A, Davies D, Hogg N. 2002. Signaling through integrin LFA-1 leads to filamentous actin polymerization and remodeling, resulting in enhanced T cell adhesion. J Immunol 168:6330-6335. (Pubitemid 34620055)
28. Rees DJ, Ades SE, Singer SJ, Hynes RO. 1990. Sequence and domain structure of talin. Nature 347:685-689.
29. Roth SJ, Carr MW, Rose SS, Springer TA. 1995. Characterization of transendothelial chemotaxis of T lymphocytes. J Immunol Methods 188:97-116.
30. Sampath R, Gallagher PJ, Pavalko FM. 1998. Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin. J Biol Chem 273:33588-33594. (Pubitemid 129754433)
31. Samstag Y, Eibert SM, Klemke M, Wabnitz GH. 2003. Actin cytoskeletal dynamics in T lymphocyte activation and migration. J Leukoc Biol 73:30-48. (Pubitemid 36125673)
32. Sánchez-Madrid F, del Pozo MA. 1999. Leukocyte polarization in cell migration and immune interactions. EMBO J 18:501-511. (Pubitemid 29057235)
33. Schaller MD, Otey CA, Hildebrand JD, Parsons JT. 1995. Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J Cell Biol 130:1181-1187.
34. Sharma CP, Ezzell RM, Arnaout MA. 1995. Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18. J Immunol 154:3461-3470.
35. Sivaraman J, Nägler DK, Zhang R, Ménard R, Cygler M. 2000. Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine. J Mol Biol 295:939-951. (Pubitemid 30700936)
36. Skrzydlewska E, Sulkowska M, Koda M, Sulkowski S. 2005. Proteolytic- antiproteolytic balance and its regulation in carcinogenesis. World J Gastroenterol 11:1251-1266. (Pubitemid 40425906)
37. Smith A, Bracke M, Leitinger B, Porter JC, Hogg N. 2003. LFA-1- induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment. J Cell Sci 116:3123-3133. (Pubitemid 37038961)
38. Smith A, Carrasco YR, Stanley P, Kieffer N, Batista FD, Hogg N. 2005. A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes. J Cell Biol 170:141-151. (Pubitemid 40994103)
39. Smith A, Stanley P, Jones K, Svensson L, McDowall A, Hogg N. 2007. The role of the integrin LFA-1 in T-lymphocyte migration. Immunol Rev 218:135-146. (Pubitemid 47052307)
40. Stanley P, Smith A, McDowall A, Nicol A, Zicha D, Hogg N. 2008. Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell. EMBO J 27:62-75.
41. Stossel TP. 1993. On the crawling of animal cells. Science 260:1086-1094.
42. Strojnik T, Zidanik B, Kos J, Lah TT. 2001. Cathepsins B and L are markers for clinically invasive types of meningiomas. Neurosurgery 48:598-605. (Pubitemid 32199609)
43. Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA. 2003. Talin binding to integrin beta tails: a final common step in integrin activation. Science 302:103-106. (Pubitemid 37210697)
44. Tang P, Cao C, Xu M, Zhang L. 2007. Cytoskeletal protein radixin activates integrin alpha(M)beta(2) by binding to its cytoplasmic tail. FEBS Lett 581:1103-1108.
45. Tsuge H, Nishimura T, Tada Y, Asao T, Turk D, Turk V, Katunuma N. 1999. Inhibition mehanism of cathepsin-L specific inhibitors based on the crystal structure of papain-CLIK148 complex. Biochem Biophys Res Commun 266:411-416. (Pubitemid 30028682)
46. Vicente-Manzanares M, Sánchez-Madrid F. 2004. Role of the cytoskeleton during leukocyte responses. Nat Rev Immunol 4:110-122.
47. Volkov Y, Long A, McGrath S, Ni Eidhin D, Kelleher D. 2001. Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells. Nat Immunol 2:508-514. (Pubitemid 33705852)
48. Yang Z, Cox JL. 2007. Cathepsin L increases invasion and migration of B16 melanoma. Cancer Cell Int 7:8. (Pubitemid 46902104)
49. Wolf K, Müller R, Borgmann S, Bröcker EB, Friedl P. 2003. Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases. Blood 102:3262-3269. (Pubitemid 37314765)