메뉴 건너뛰기




Volumn 32, Issue 5, 2009, Pages 484-490

CL097, A TLR7/8 Ligand, inhibits TLR-4-dependent activation of IRAK-M and BCL-3 expression

Author keywords

Bcl 3; Cytokines; Immunosuppression; IRAK M; LPS; TLR

Indexed keywords

ANTINEOPLASTIC AGENT; CL 097; HYALURONIC ACID; IMIDAZOQUINOLINE DERIVATIVE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE M; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; PROTEIN BCL 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 70350221029     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181a5ac8a     Document Type: Article
Times cited : (16)

References (32)
  • 3
    • 33646778526 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced tumor necrosis factor alpha production and not monocyte human leukocyte antigen-DR expression is correlated with survival in septic trauma patients
    • Ploder M, Pelinka L, Schmuckenschlager C, Wessner B, Ankersmit HJ, Fuerst W, Redl H, Roth E, Spittler A: Lipopolysaccharide-induced tumor necrosis factor alpha production and not monocyte human leukocyte antigen-DR expression is correlated with survival in septic trauma patients. Shock 25:129-134, 2006.
    • (2006) Shock , vol.25 , pp. 129-134
    • Ploder, M.1    Pelinka, L.2    Schmuckenschlager, C.3    Wessner, B.4    Ankersmit, H.J.5    Fuerst, W.6    Redl, H.7    Roth, E.8    Spittler, A.9
  • 6
    • 67650401419 scopus 로고    scopus 로고
    • Immunosuppression associated with interleukin-1RYassociatedYkinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis)
    • Dec 26. [Epub ahead of print]
    • Wiersinga WJ, Van't Veer C, van den Pangaart PS, Dondorp AM, Day NP, Peacock SJ, van der Poll T: Immunosuppression associated with interleukin-1RYassociatedYkinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis). Crit Care Med 2009 Dec 26. [Epub ahead of print].
    • (2009) Crit Care Med
    • Wiersinga, W.J.1    Van'T Veer, C.2    Van Den Pangaart, P.S.3    Dondorp, A.M.4    Day, N.P.5    Peacock, S.J.6    Van Der Poll, R.7
  • 9
    • 24644495576 scopus 로고    scopus 로고
    • Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock
    • Lin WJ, Yeh WC: Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. Shock 24:206-209, 2005.
    • (2005) Shock , vol.24 , pp. 206-209
    • Lin, W.J.1    Yeh, W.C.2
  • 11
    • 34248587897 scopus 로고    scopus 로고
    • Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth
    • Xie Q, Gan L, Wang J, Wilson I, Li L: Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth. Mol Immunol 44:3453-3461, 2007.
    • (2007) Mol Immunol , vol.44 , pp. 3453-3461
    • Xie, Q.1    Gan, L.2    Wang, J.3    Wilson, I.4    Li, L.5
  • 13
    • 9644268197 scopus 로고    scopus 로고
    • BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages
    • Wessells J, Baer M, Young HA, Claudio E, Brown K, Siebenlist V, Johnson PF: BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages. J Biol Chem 279:49995-50003, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 49995-50003
    • Wessells, J.1    Baer, M.2    Young, H.A.3    Claudio, E.4    Brown, K.5    Siebenlist, V.6    Johnson, P.F.7
  • 14
    • 34547815755 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade
    • Carmody RJ, Ruan Q, Palmer S, Hilliard B, Chen YH: Negative regulation of Toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade. Science 317:675-678, 2007.
    • (2007) Science , vol.317 , pp. 675-678
    • Carmody, R.J.1    Ruan, Q.2    Palmer, S.3    Hilliard, B.4    Chen, Y.H.5
  • 16
    • 33847183077 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor signals in innate immune defence
    • Trinchieri G, Sher A: Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 7:179-190, 2007.
    • (2007) Nat Rev Immunol , vol.7 , pp. 179-190
    • Trinchieri, G.1    Sher, A.2
  • 17
    • 23644449245 scopus 로고    scopus 로고
    • The expression of Tolllike receptors 3 and 7 in rheumatoid arthritis synovium is increased and co-stimulation of Toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells
    • Roelofs MF, Joosten LA, Abdollahi-Roodsaz S, van Lieshout AW, Sprong T, van den Hoogen FH, van den Berg WB, Radstake TR: The expression of Tolllike receptors 3 and 7 in rheumatoid arthritis synovium is increased and co-stimulation of Toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells. Arthritis Rheum 52:2313-2322, 2005.
    • (2005) Arthritis Rheum , vol.52 , pp. 2313-2322
    • Roelofs, M.F.1    Joosten, L.A.2    Abdollahi-Roodsaz, S.3    Van Lieshout, A.W.4    Sprong, T.5    Van Den Hoogen, F.H.6    Van Den Berg, W.B.7    Radstake, T.R.8
  • 18
    • 23944489407 scopus 로고    scopus 로고
    • Selected Tolllike receptor agonist combinations synergistically trigger a T helper type 1Ypolarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A: Selected Tolllike receptor agonist combinations synergistically trigger a T helper type 1Ypolarizing program in dendritic cells. Nat Immunol 6:769-776, 2005.
    • (2005) Nat Immunol , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 21
    • 0242362818 scopus 로고    scopus 로고
    • Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients
    • Escoll P, del Fresno C, Garcia L, Valles G, Lendinez MJ, Arnalich F, Lopez-Collazo E: Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients. Biochem Biophys Res Commun 311:465-472, 2003.
    • (2003) Biochem Biophys Res Commun , vol.311 , pp. 465-472
    • Escoll, P.1    Del Fresno, C.2    Garcia, L.3    Valles, G.4    Lendinez, M.J.5    Arnalich, F.6    Lopez-Collazo, E.7
  • 23
    • 43049102416 scopus 로고    scopus 로고
    • The antiviral activity of Toll-like receptor 7 and 7/8 agonists
    • Miller RL, Meng TC, Tomai MA: The antiviral activity of Toll-like receptor 7 and 7/8 agonists. Drug News Perspect 21:69-87, 2008.
    • (2008) Drug News Perspect , vol.21 , pp. 69-87
    • Miller, R.L.1    Meng, T.C.2    Tomai, M.A.3
  • 25
    • 33846207958 scopus 로고    scopus 로고
    • MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists
    • Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C, Hellman J: MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J Immunol 178:1164-1171, 2007.
    • (2007) J Immunol , vol.178 , pp. 1164-1171
    • Bagchi, A.1    Herrup, E.A.2    Warren, H.S.3    Trigilio, J.4    Shin, H.S.5    Valentine, C.6    Hellman, J.7
  • 27
    • 34247569887 scopus 로고    scopus 로고
    • The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis
    • Hattermann K, Picard S, Borgeat M, Leclerc P, Pouliot M, Borgeat P: The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis. FASEB J 21:1575-1585, 2007.
    • (2007) FASEB J , vol.21 , pp. 1575-1585
    • Hattermann, K.1    Picard, S.2    Borgeat, M.3    Leclerc, P.4    Pouliot, M.5    Borgeat, P.6
  • 28
    • 0037201295 scopus 로고    scopus 로고
    • Immunomodulatory effects of vasoactive catechol-amines
    • Bergmann M, Sautner T: Immunomodulatory effects of vasoactive catechol-amines. Wien Klin Wochenschr 114:752-761, 2002.
    • (2002) Wien Klin Wochenschr , vol.114 , pp. 752-761
    • Bergmann, M.1    Sautner, T.2
  • 29
    • 20644450804 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptorYmediated immune responses
    • Liew FY, Xu D, Brint EK, O'Neill LA: Negative regulation of Toll-like receptorYmediated immune responses. Nat Rev Immunol 5:446-458, 2005.
    • (2005) Nat Rev Immunol , vol.5 , pp. 446-458
    • Liew, F.Y.1    Xu, D.2    Brint, E.K.3    O'Neill, L.A.4
  • 30
    • 53249098838 scopus 로고    scopus 로고
    • Up-regulation of IRAK-M is essential for endotoxin tolerance induced by a low dose of lipopolysaccharide in Kupffer cells
    • Liu ZJ, Yan LN, Li XH, Xu FL, Chen XF, You HB, Gong JP: Up-regulation of IRAK-M is essential for endotoxin tolerance induced by a low dose of lipopolysaccharide in Kupffer cells. J Surg Res 150:34-39, 2008.
    • (2008) J Surg Res , vol.150 , pp. 34-39
    • Liu, Z.J.1    Yan, L.N.2    Li, X.H.3    Xu, F.L.4    Chen, X.F.5    You, H.B.6    Gong, J.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.