Attenuation of catecholamine-induced immunosuppression in whole blood from patients with sepsis

Shock

Volumn 12, Issue 6, 1999, Pages 421-427

  Bergmann, Michael ^a   Gornikiewicz, Alexander ^a   Sautner, Thomas ^a   Waldmann, Elke ^a   Weber, Thomas ^a   Mittlböck, Martina ^a   Roth, Erich ^a   Függer, Reinhold ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BETA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CATECHOLAMINE; CYTOKINE; DOBUTAMINE; DOPAMINE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; METOPROLOL; NORADRENALIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BIOSYNTHESIS; BLOOD; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GRANULOCYTE; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MIDDLE AGED; MONOCYTE; PHYSIOLOGY; SEPTIC SHOCK;

ADRENERGIC BETA-ANTAGONISTS; ADULT; CATECHOLAMINES; CYTOKINES; DOBUTAMINE; DOPAMINE; EPINEPHRINE; GENE EXPRESSION REGULATION; GRANULOCYTES; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; METOPROLOL; MIDDLE AGED; MONOCYTES; NOREPINEPHRINE; RECEPTORS, ADRENERGIC, BETA-1; RNA, MESSENGER; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033258466     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199912000-00002     Document Type: Article

References (23)

1. Severn A, Rapson NT, Hunter CA, Liew JW: Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists. J Immun 148:3441-3445, 1992.
2. van der Poll T, Coyle SM, Barbosa K, Braxton CC, Lowry SF: Epinephrine inhibits tumor necrosis factor alpha and potentates interleukin-10 production during human endotoxemia. J Clin Invest 97:713-719, 1996.
3. van der Poll T, Jansen J, Endert E, Sauerwein EH, van Deventer SJH: Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin-6 production in human whole blood. Infect Immun 62: 2046-2050, 1994.
4. van der Poll T, Lowry SF: Epinephrine inhibits endotoxin-induced IL-1 beta production: roles of tumor necrosis factor-alpha and IL-10. Am J Physiol 273:R1885-1890, 1997.
5. de Waal Malefyt R, Abrams J, Bennet B, Figdor CG, de Vries JE: Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med 174: 1209-1220, 1991.
6. Woiciechowsky C, Asadulluh K, Nestler D, Eberhardt B, Platzer C, Schöning B, Glöckner B, Lanksch W, Volk HD, Döcke WD: Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Nature Med 4:808-813, 1998.
7. Monastra G, Secchi EF: Beta-adrenergic receptors mediate in vivo the adrenaline inhibition of lipopolysaccharide-induced tumor necrosis factor release. Immun Lett 38:127-130, 1993.
8. Beutler B. Endotoxin, Tumor necrosis factor, and related molecules: new approaches to shock. New Horiz 1:3-12, 1993.
9. Thijs LG, Hack CE: Time course of cytokine levels in sepsis. Int Care Med 21:S258-S263, 1995.
10. Volk HD, Reinke P, Krausch D, Zuckermann H, Asadullah K, Muller JM, Docke WD, Kox WJ: Monocyte deactivation - rationale for a new therapeutic strategy in sepsis. Int Care Med 22:S474-S481, 1996.
11. Munoz C, Carlet J, Fitting C, Misset B, Blériot JP, Cavaillon JM. Dysregulation of in vitro cytokine production by monocytes during sepsis. J Clin Invest 88:1747-1754, 1991.
12. Ertel W, Kremer JP, Kenney J, Stechholzer U, Jarrar D, Trentz O, Schildberg FW: Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 85:1341-1347, 1995.
13. Marchant A, Deviere J, Byl B, De Groote D, Vincent JL, Goldman M: Interleukin-10 production during septicemia. Lancet 343:707-708, 1994.
14. Sherry RM, Cue JI, Goddard JK, Parramore JB, DiPiro JT: Interleukin-10 is associated with the development of sepsis in trauma patients. J Trauma 40:613-616, 1996.
15. Bogdan C, Paik J, Vodovotz Y, Nathan C: Contrasting mechanism for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin 10. J Biol Chem 267:23301-23308, 1992.
16. Fong Y, Marano MA, Moldawer LL Wei H, Calvano SE, Kenney JS, Allison AC, Cerami A, Shires GT, Lowry SF: The acute splanchnic and peripheral tissue response to endotoxin in man in humans. J Clin Invest 85:1896-1905, 1990.
17. Vaughan GM, Becker RA, Allen JP, Goodwin CW Jr, Pruitt BA Jr, Mason AD Jr: Cortisol and corticothrophin in burned patients. J Trauma 22:263-270, 1982.
18. Members of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20:864-874, 1992.
19. Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ: Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 23:1638-1652, 1995.
20. Sambrook J, Fritsch EF, Maniatis T: Molecular cloning. A laboratory manual. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 1989, pp 7.39-7.52.
21. Sautner T, Götzinger P, Redl-Wenzl EM, Dittrich K, Felfernig M, Sporn P, Roth E, Függer R: Does reoperation for abdominal sepsis enhance the inflammatory host response? Arch Surg 132:250-255, 1997.
22. Cassatella MA: The production of cytokines by polymorphonuclear neutrophils. Immunol Today 16:21-26, 1995.
23. Baue AE, Günther B, Hartl W, Ackenheil M, Heberer G: Altered homonal activity in severely ill patients after injury or sepsis. Arch Surg 111:1125-1132, 1984.