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Volumn 45, Issue 6, 2009, Pages 1034-1043

Increased calcium content and inhomogeneity of mineralization render bone toughness in osteoporosis: Mineralization, morphology and biomechanics of human single trabeculae

Author keywords

Biomechanics; Bone histomorphometry; Bone mineralization; Materials testing; Osteoporosis

Indexed keywords

CALCIUM;

EID: 70350212810     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.08.002     Document Type: Article
Times cited : (151)

References (64)
  • 1
    • 84924706624 scopus 로고    scopus 로고
    • Princeton University Press, Princeton, N.J, USA
    • st ed. vol. 1 (2002), Princeton University Press, Princeton, N.J, USA
    • (2002) st ed. , vol.1
    • Currey, J.D.1
  • 2
    • 0030956347 scopus 로고    scopus 로고
    • From density to structure: growing up and growing old on the surfaces of bone
    • Seeman E. From density to structure: growing up and growing old on the surfaces of bone. J. Bone Miner. Res. 12 4 (1997) 509-521
    • (1997) J. Bone Miner. Res. , vol.12 , Issue.4 , pp. 509-521
    • Seeman, E.1
  • 3
    • 33646889773 scopus 로고    scopus 로고
    • Bone quality-the material and structural basis of bone strength and fragility
    • Seeman E., and Delmas P.D. Bone quality-the material and structural basis of bone strength and fragility. N. Engl. J. Med. 25 354(21) (2006) 2250-2261
    • (2006) N. Engl. J. Med. , vol.25 , Issue.354 21 , pp. 2250-2261
    • Seeman, E.1    Delmas, P.D.2
  • 4
    • 0036279670 scopus 로고    scopus 로고
    • The impact of bone turnover and bone-active agents on bone quality: focus on the hip
    • Dempster D.W. The impact of bone turnover and bone-active agents on bone quality: focus on the hip. Osteoporos. Int. 13 5 (2002) 349-352
    • (2002) Osteoporos. Int. , vol.13 , Issue.5 , pp. 349-352
    • Dempster, D.W.1
  • 6
    • 0028306362 scopus 로고
    • Assessment of fracture risk and its application to screening for postmenopausal osteoporosis
    • Report of a WHO Study Group
    • Report of a WHO Study Group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. World Health Organ Tech. Rep. Ser. 843 (1994) 1-129
    • (1994) World Health Organ Tech. Rep. Ser. , vol.843 , pp. 1-129
  • 8
    • 0038753019 scopus 로고    scopus 로고
    • DXA scanning to diagnose osteoporosis: do you know what the results mean?
    • Richmond B. DXA scanning to diagnose osteoporosis: do you know what the results mean?. Clevel. Clin. J. Med. 70 4 (2003) 353-360
    • (2003) Clevel. Clin. J. Med. , vol.70 , Issue.4 , pp. 353-360
    • Richmond, B.1
  • 9
    • 0034093030 scopus 로고    scopus 로고
    • Dual X-ray absorptiometry: recognizing image artifacts and pathology
    • Jacobson J.A., Jamadar D.A., and Hayes C.W. Dual X-ray absorptiometry: recognizing image artifacts and pathology. AJR Am. J. Roentgenol. 174 6 (2000) 1699-1705
    • (2000) AJR Am. J. Roentgenol. , vol.174 , Issue.6 , pp. 1699-1705
    • Jacobson, J.A.1    Jamadar, D.A.2    Hayes, C.W.3
  • 10
    • 67649641790 scopus 로고    scopus 로고
    • Spatial and temporal variations of mechanical properties and mineral content of the external callus during bone healing
    • Manjubala I., Liu Y., Epari D.R., Roschger P., Schell H., Fratzl P., et al. Spatial and temporal variations of mechanical properties and mineral content of the external callus during bone healing. Bone 45 2 (2009 Aug) 185-192
    • (2009) Bone , vol.45 , Issue.2 , pp. 185-192
    • Manjubala, I.1    Liu, Y.2    Epari, D.R.3    Roschger, P.4    Schell, H.5    Fratzl, P.6
  • 11
    • 0033811529 scopus 로고    scopus 로고
    • If bone is the answer, then what is the question?
    • Huiskes R. If bone is the answer, then what is the question?. J. Anat. 197 Pt 2 (2000) 145-156
    • (2000) J. Anat. , vol.197 , Issue.PART 2 , pp. 145-156
    • Huiskes, R.1
  • 12
    • 0042807480 scopus 로고    scopus 로고
    • How well are bones designed to resist fracture?
    • Currey J.D. How well are bones designed to resist fracture?. J. Bone Miner. Res. 18 4 (2003) 591-598
    • (2003) J. Bone Miner. Res. , vol.18 , Issue.4 , pp. 591-598
    • Currey, J.D.1
  • 13
    • 33644968292 scopus 로고    scopus 로고
    • Effect of microstructure on the mechanical properties of Haversian cortical bone
    • Hoc T., Henry L., Verdier M., Aubry D., Sedel L., and Meunier A. Effect of microstructure on the mechanical properties of Haversian cortical bone. Bone 38 4 (2006) 466-474
    • (2006) Bone , vol.38 , Issue.4 , pp. 466-474
    • Hoc, T.1    Henry, L.2    Verdier, M.3    Aubry, D.4    Sedel, L.5    Meunier, A.6
  • 15
    • 0026070777 scopus 로고
    • Undecalcified preparation of bone tissue: report of technical experience and development of new methods
    • Hahn M., Vogel M., and Delling G. Undecalcified preparation of bone tissue: report of technical experience and development of new methods. Virchows Arch. A Pathol. Anat. Histopathol. 418 1 (1991) 1-7
    • (1991) Virchows Arch. A Pathol. Anat. Histopathol. , vol.418 , Issue.1 , pp. 1-7
    • Hahn, M.1    Vogel, M.2    Delling, G.3
  • 16
    • 0028064534 scopus 로고
    • Three-dimensional analysis of the spine in autopsy cases with renal osteodystrophy
    • Amling M., Grote H.J., Vogel M., Hahn M., and Delling G. Three-dimensional analysis of the spine in autopsy cases with renal osteodystrophy. Kidney Int. 46 3 (1994) 733-743
    • (1994) Kidney Int. , vol.46 , Issue.3 , pp. 733-743
    • Amling, M.1    Grote, H.J.2    Vogel, M.3    Hahn, M.4    Delling, G.5
  • 17
    • 70350239170 scopus 로고    scopus 로고
    • Busse B, Hahn M, Schinke T, Püschel K, Duda GN, Amling M. Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling. J Biomed Mater Res A. Electronic publication ahead of print 2009 Apr 9.
    • Busse B, Hahn M, Schinke T, Püschel K, Duda GN, Amling M. Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling. J Biomed Mater Res A. Electronic publication ahead of print 2009 Apr 9.
  • 18
    • 0023488581 scopus 로고
    • Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2 6 (1987) 595-610
    • (1987) J. Bone Miner. Res. , vol.2 , Issue.6 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6
  • 19
    • 0029969893 scopus 로고    scopus 로고
    • Architecture and distribution of cancellous bone yield vertebral fracture clues. A histomorphometric analysis of the complete spinal column from 40 autopsy specimens
    • Amling M., Pösl M., Ritzel H., Hahn M., Vogel M., Wening V.J., et al. Architecture and distribution of cancellous bone yield vertebral fracture clues. A histomorphometric analysis of the complete spinal column from 40 autopsy specimens. Arch. Orthop. Trauma. Surg. 115 5 (1996) 262-269
    • (1996) Arch. Orthop. Trauma. Surg. , vol.115 , Issue.5 , pp. 262-269
    • Amling, M.1    Pösl, M.2    Ritzel, H.3    Hahn, M.4    Vogel, M.5    Wening, V.J.6
  • 20
    • 0027173883 scopus 로고
    • Relation between 2- and 3-dimensional architecture of trabecular bone in the human spine
    • Vogel M., Hahn M., and Delling G. Relation between 2- and 3-dimensional architecture of trabecular bone in the human spine. Bone 14 3 (1993 May-Jun) 199-203
    • (1993) Bone , vol.14 , Issue.3 , pp. 199-203
    • Vogel, M.1    Hahn, M.2    Delling, G.3
  • 21
    • 0029151175 scopus 로고
    • Intervertebral variation in trabecular microarchitecture throughout the normal spine in relation to age
    • Grote H.J., Amling M., Vogel M., Hahn M., Pösl M., and Delling G. Intervertebral variation in trabecular microarchitecture throughout the normal spine in relation to age. Bone 16 3 (1995 Mar) 301-308
    • (1995) Bone , vol.16 , Issue.3 , pp. 301-308
    • Grote, H.J.1    Amling, M.2    Vogel, M.3    Hahn, M.4    Pösl, M.5    Delling, G.6
  • 22
    • 70350230691 scopus 로고    scopus 로고
    • Seitz S, Schnabel C, Busse B, Schmidt HU, Beil FT, Friedrich RE, et al. High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1. Electronic publication ahead of print Osteoporos Int 2009 May 5.
    • Seitz S, Schnabel C, Busse B, Schmidt HU, Beil FT, Friedrich RE, et al. High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1. Electronic publication ahead of print Osteoporos Int 2009 May 5.
  • 23
    • 0007506435 scopus 로고    scopus 로고
    • Scanning electron microscopy of bone: instrument, specimen, and issues
    • Boyde A., and Jones S.J. Scanning electron microscopy of bone: instrument, specimen, and issues. Microsc. Res. Tech. 1 33(2) (1996) 92-120
    • (1996) Microsc. Res. Tech. , vol.1 , Issue.33 2 , pp. 92-120
    • Boyde, A.1    Jones, S.J.2
  • 24
    • 0027398456 scopus 로고
    • Influence of mineral content and composition on graylevels in backscattered electron images of bone
    • Skedros J.G., Bloebaum R.D., Bachus K.N., Boyce T.M., and Constantz B. Influence of mineral content and composition on graylevels in backscattered electron images of bone. J. Biomed. Mat. Res. 27 (1993) 57-64
    • (1993) J. Biomed. Mat. Res. , vol.27 , pp. 57-64
    • Skedros, J.G.1    Bloebaum, R.D.2    Bachus, K.N.3    Boyce, T.M.4    Constantz, B.5
  • 25
    • 0028882234 scopus 로고
    • A new scanning electron microscopy approach to the quantification of bone mineral distribution: backscattered electron image grey-levels correlated to calcium K alpha-line intensities
    • Roschger P., Plenk H., Klaushofer K., and Eschberger J. A new scanning electron microscopy approach to the quantification of bone mineral distribution: backscattered electron image grey-levels correlated to calcium K alpha-line intensities. Scanning Microsc. 9 (1995) 75-86
    • (1995) Scanning Microsc. , vol.9 , pp. 75-86
    • Roschger, P.1    Plenk, H.2    Klaushofer, K.3    Eschberger, J.4
  • 26
    • 17644445505 scopus 로고    scopus 로고
    • Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies
    • Roschger P., Fratzl P., Eschberger J., and Klaushofer K. Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies. Bone 23 (1998) 319-326
    • (1998) Bone , vol.23 , pp. 319-326
    • Roschger, P.1    Fratzl, P.2    Eschberger, J.3    Klaushofer, K.4
  • 27
    • 37349074523 scopus 로고    scopus 로고
    • Quantitative backscattered electron imaging of bone in proximal femur fragility fracture and medical illness
    • Sutton-Smith P., Beard H., and Fazzalari N. Quantitative backscattered electron imaging of bone in proximal femur fragility fracture and medical illness. J. Microsc. 229 Pt 1 (2008) 60-66
    • (2008) J. Microsc. , vol.229 , Issue.PART 1 , pp. 60-66
    • Sutton-Smith, P.1    Beard, H.2    Fazzalari, N.3
  • 28
    • 39149107458 scopus 로고    scopus 로고
    • Bone mineralization density distribution in health and disease
    • Roschger P., Paschalis E.P., Fratzl P., and Klaushofer K. Bone mineralization density distribution in health and disease. Bone 42 3 (2008) 456-466
    • (2008) Bone , vol.42 , Issue.3 , pp. 456-466
    • Roschger, P.1    Paschalis, E.P.2    Fratzl, P.3    Klaushofer, K.4
  • 29
    • 0028650369 scopus 로고
    • Polyostotic heterogeneity of the spine in osteoporosis. Quantitative analysis and three-dimensional morphology
    • Amling M., Grote H.J., Pösl M., Hahn M., and Delling G. Polyostotic heterogeneity of the spine in osteoporosis. Quantitative analysis and three-dimensional morphology. Bone Miner. 27 3 (1994) 193-208
    • (1994) Bone Miner. , vol.27 , Issue.3 , pp. 193-208
    • Amling, M.1    Grote, H.J.2    Pösl, M.3    Hahn, M.4    Delling, G.5
  • 30
    • 0027499810 scopus 로고
    • Relationships between bone structure in the iliac crest and bone structure and strength in the lumbar spine
    • Dempster D.W., Ferguson-Pell M.W., Mellish R.W., Cochran G.V., Xie F., Fey C., et al. Relationships between bone structure in the iliac crest and bone structure and strength in the lumbar spine. Osteoporos. Int. 3 2 (1993) 90-96
    • (1993) Osteoporos. Int. , vol.3 , Issue.2 , pp. 90-96
    • Dempster, D.W.1    Ferguson-Pell, M.W.2    Mellish, R.W.3    Cochran, G.V.4    Xie, F.5    Fey, C.6
  • 31
    • 0036138698 scopus 로고    scopus 로고
    • Static histomorphometry of human iliac crest and vertebral trabecular bone: a comparative study
    • Thomsen J.S., Ebbesen E.N., and Mosekilde L. Static histomorphometry of human iliac crest and vertebral trabecular bone: a comparative study. Bone 30 1 (2002 Jan) 267-274
    • (2002) Bone , vol.30 , Issue.1 , pp. 267-274
    • Thomsen, J.S.1    Ebbesen, E.N.2    Mosekilde, L.3
  • 32
    • 0030051521 scopus 로고    scopus 로고
    • Heterogeneity of the skeleton: comparison of the trabecular microarchitecture of the spine, the iliac crest, the femur, and the calcaneus
    • Amling M., Herden S., Pösl M., Hahn M., Ritzel H., and Delling G. Heterogeneity of the skeleton: comparison of the trabecular microarchitecture of the spine, the iliac crest, the femur, and the calcaneus. J. Bone Miner. Res. 11 1 (1996) 36-45
    • (1996) J. Bone Miner. Res. , vol.11 , Issue.1 , pp. 36-45
    • Amling, M.1    Herden, S.2    Pösl, M.3    Hahn, M.4    Ritzel, H.5    Delling, G.6
  • 33
    • 18444365600 scopus 로고    scopus 로고
    • Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies
    • Thomsen J.S., Laib A., Koller B., Prohaska S., Mosekilde L., and Gowin W. Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies. J. Microsc. 218 Pt 2 (2005 May) 171-179
    • (2005) J. Microsc. , vol.218 , Issue.PART 2 , pp. 171-179
    • Thomsen, J.S.1    Laib, A.2    Koller, B.3    Prohaska, S.4    Mosekilde, L.5    Gowin, W.6
  • 34
    • 0025200816 scopus 로고
    • The elastic moduli of human subchondral, trabecular, and cortical bone tissue and the size-dependency of cortical bone modulus
    • Choi K., Kuhn J.L., Ciarelli M.J., and Goldstein S.A. The elastic moduli of human subchondral, trabecular, and cortical bone tissue and the size-dependency of cortical bone modulus. J. Biomech. 23 11 (1990) 1103-1113
    • (1990) J. Biomech. , vol.23 , Issue.11 , pp. 1103-1113
    • Choi, K.1    Kuhn, J.L.2    Ciarelli, M.J.3    Goldstein, S.A.4
  • 36
    • 0034510062 scopus 로고    scopus 로고
    • Micromechanical testing of bone trabeculae: potentials and limitations
    • Lucchinetti E., Thomann D., and Danuser G. Micromechanical testing of bone trabeculae: potentials and limitations. J. Mater. Sci. 35 (2000) 6057-6064
    • (2000) J. Mater. Sci. , vol.35 , pp. 6057-6064
    • Lucchinetti, E.1    Thomann, D.2    Danuser, G.3
  • 37
    • 31344455165 scopus 로고    scopus 로고
    • Stress-concentrating effect of resorption lacunae in trabecular bone
    • McNamara L.M., Van der Linden J.C., Weinans H., and Prendergast P.J. Stress-concentrating effect of resorption lacunae in trabecular bone. J. Biomech. 39 4 (2006) 734-741
    • (2006) J. Biomech. , vol.39 , Issue.4 , pp. 734-741
    • McNamara, L.M.1    Van der Linden, J.C.2    Weinans, H.3    Prendergast, P.J.4
  • 38
    • 0023868463 scopus 로고
    • On the dependence of the elasticity and strength of cancellous bone on apparent density
    • Rice J.C., Cowin S.C., and Bowman J.A. On the dependence of the elasticity and strength of cancellous bone on apparent density. J. Biomech. 21 2 (1988) 155-168
    • (1988) J. Biomech. , vol.21 , Issue.2 , pp. 155-168
    • Rice, J.C.1    Cowin, S.C.2    Bowman, J.A.3
  • 39
    • 0032029664 scopus 로고    scopus 로고
    • Mechanical properties and the hierarchical structure of bone
    • Rho J.Y., Kuhn-Spearing L., and Zioupos P. Mechanical properties and the hierarchical structure of bone. Med. Eng. Phys. 20 2 (1998) 92-102
    • (1998) Med. Eng. Phys. , vol.20 , Issue.2 , pp. 92-102
    • Rho, J.Y.1    Kuhn-Spearing, L.2    Zioupos, P.3
  • 40
    • 0034763706 scopus 로고    scopus 로고
    • Trabecular bone's mechanical properties are affected by its non-uniform mineral distribution
    • van der Linden J.C., Birkenhäger-Frenkel D.H., Verhaar J.A., and Weinans H. Trabecular bone's mechanical properties are affected by its non-uniform mineral distribution. J. Biomech. 34 12 (2001) 1573-1580
    • (2001) J. Biomech. , vol.34 , Issue.12 , pp. 1573-1580
    • van der Linden, J.C.1    Birkenhäger-Frenkel, D.H.2    Verhaar, J.A.3    Weinans, H.4
  • 41
    • 0024209735 scopus 로고
    • Composition of the cement line and its possible mechanical role as a local interface in human compact bone
    • Burr D.B., Schaffler M.B., and Frederickson R.G. Composition of the cement line and its possible mechanical role as a local interface in human compact bone. J. Biomech. 21 11 (1988) 939-945
    • (1988) J. Biomech. , vol.21 , Issue.11 , pp. 939-945
    • Burr, D.B.1    Schaffler, M.B.2    Frederickson, R.G.3
  • 42
    • 0026990532 scopus 로고
    • A comparison of the fatigue behavior of human trabecular and cortical bone tissue
    • Choi K., and Goldstein S.A. A comparison of the fatigue behavior of human trabecular and cortical bone tissue. J. Biomech. 25 12 (1992) 1371-1381
    • (1992) J. Biomech. , vol.25 , Issue.12 , pp. 1371-1381
    • Choi, K.1    Goldstein, S.A.2
  • 43
    • 25144435387 scopus 로고    scopus 로고
    • Cement lines of secondary osteons in human bone are not mineral-deficient: new data in a historical perspective
    • Skedros J.G., Holmes J.L., Vajda E.G., and Bloebaum R.D. Cement lines of secondary osteons in human bone are not mineral-deficient: new data in a historical perspective. Anat. Rec. A Discov. Mol. Cell. Evol. Biol. 286 1 (2005) 781-803
    • (2005) Anat. Rec. A Discov. Mol. Cell. Evol. Biol. , vol.286 , Issue.1 , pp. 781-803
    • Skedros, J.G.1    Holmes, J.L.2    Vajda, E.G.3    Bloebaum, R.D.4
  • 44
    • 33744945021 scopus 로고    scopus 로고
    • Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing
    • McNamara L.M., Ederveen A.G., Lyons C.G., Price C., Schaffler M.B., Weinans H., et al. Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing. Bone 39 2 (2006) 392-400
    • (2006) Bone , vol.39 , Issue.2 , pp. 392-400
    • McNamara, L.M.1    Ederveen, A.G.2    Lyons, C.G.3    Price, C.4    Schaffler, M.B.5    Weinans, H.6
  • 45
    • 0032032059 scopus 로고    scopus 로고
    • Effect of estrogen suppression on the mineralization density of iliac crest biopsies in young women as assessed by backscattered electron imaging
    • Boyde A., Compston J.E., Reeve J., Bell K.L., Noble B.S., Jones S.J., et al. Effect of estrogen suppression on the mineralization density of iliac crest biopsies in young women as assessed by backscattered electron imaging. Bone 22 3 (1998) 241-250
    • (1998) Bone , vol.22 , Issue.3 , pp. 241-250
    • Boyde, A.1    Compston, J.E.2    Reeve, J.3    Bell, K.L.4    Noble, B.S.5    Jones, S.J.6
  • 46
    • 0035658186 scopus 로고    scopus 로고
    • The temporal changes of trabecular architecture in ovariectomized rats assessed by MicroCT
    • Laib A., Kumer J.L., Majumdar S., and Lane N.E. The temporal changes of trabecular architecture in ovariectomized rats assessed by MicroCT. Osteoporos. Int. 12 11 (2001) 936-941
    • (2001) Osteoporos. Int. , vol.12 , Issue.11 , pp. 936-941
    • Laib, A.1    Kumer, J.L.2    Majumdar, S.3    Lane, N.E.4
  • 47
    • 59249105230 scopus 로고    scopus 로고
    • Oral ibandronate preserves trabecular microarchitecture: micro-computed tomography findings from the oral ibandronate osteoporosis vertebral fracture trial in North America and Europe study
    • Recker R.R., Ste-Marie L.G., Langdahl B., Masanauskaite D., Ethgen D., and Delmas P.D. Oral ibandronate preserves trabecular microarchitecture: micro-computed tomography findings from the oral ibandronate osteoporosis vertebral fracture trial in North America and Europe study. J. Clin. Densitom. 12 1 (2009 Jan-Mar) 71-76
    • (2009) J. Clin. Densitom. , vol.12 , Issue.1 , pp. 71-76
    • Recker, R.R.1    Ste-Marie, L.G.2    Langdahl, B.3    Masanauskaite, D.4    Ethgen, D.5    Delmas, P.D.6
  • 48
    • 0029329134 scopus 로고
    • Relations of mechanical properties to density and CT numbers in human bone
    • Rho J.Y., Hobatho M.C., and Ashman R.B. Relations of mechanical properties to density and CT numbers in human bone. Med. Eng. Phys. 17 5 (1995 Jul) 347-355
    • (1995) Med. Eng. Phys. , vol.17 , Issue.5 , pp. 347-355
    • Rho, J.Y.1    Hobatho, M.C.2    Ashman, R.B.3
  • 49
    • 0021761489 scopus 로고
    • Effects of differences in mineralization on the mechanical properties of bone
    • Currey J.D. Effects of differences in mineralization on the mechanical properties of bone. Philos. Trans. R. Soc. Lond. B Biol. Sci. 304 (1984) 509-518
    • (1984) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.304 , pp. 509-518
    • Currey, J.D.1
  • 50
    • 44649090086 scopus 로고    scopus 로고
    • Role of collagen and other organics in the mechanical properties of bone
    • Currey J.D. Role of collagen and other organics in the mechanical properties of bone. Osteoporos. Int. 14 Suppl. 5 (2003) 29-36
    • (2003) Osteoporos. Int. , vol.14 , Issue.SUPPL. 5 , pp. 29-36
    • Currey, J.D.1
  • 52
    • 0036122985 scopus 로고    scopus 로고
    • Bone material properties and mineral matrix contributions to fracture risk or age in women and men
    • Burr D.B. Bone material properties and mineral matrix contributions to fracture risk or age in women and men. J. Musculoskelet. Neuronal. Interact. 2 3 (2002) 201-204
    • (2002) J. Musculoskelet. Neuronal. Interact. , vol.2 , Issue.3 , pp. 201-204
    • Burr, D.B.1
  • 53
    • 0030087838 scopus 로고    scopus 로고
    • The effects of ageing and changes in mineral content in degrading the toughness of human femora
    • Currey J.D., Brear K., and Zioupos P. The effects of ageing and changes in mineral content in degrading the toughness of human femora. J. Biomech. 29 2 (1996) 257-260
    • (1996) J. Biomech. , vol.29 , Issue.2 , pp. 257-260
    • Currey, J.D.1    Brear, K.2    Zioupos, P.3
  • 54
    • 0027236835 scopus 로고
    • Age and disease-related changes in the mineral of bone
    • Grynpas M. Age and disease-related changes in the mineral of bone. Calcif. Tissue Int. 53 Suppl. 1 (1993) 57-64
    • (1993) Calcif. Tissue Int. , vol.53 , Issue.SUPPL. 1 , pp. 57-64
    • Grynpas, M.1
  • 55
    • 0018331354 scopus 로고
    • Changes in the impact energy absorption of bone with age
    • Currey J.D. Changes in the impact energy absorption of bone with age. J. Biomech. 12 6 (1979) 459-469
    • (1979) J. Biomech. , vol.12 , Issue.6 , pp. 459-469
    • Currey, J.D.1
  • 56
    • 0027434996 scopus 로고
    • Cortical aging differences and fracture implications for the human femoral neck
    • Boyce T.M., and Bloebaum R.D. Cortical aging differences and fracture implications for the human femoral neck. Bone 14 5 (1993) 769-778
    • (1993) Bone , vol.14 , Issue.5 , pp. 769-778
    • Boyce, T.M.1    Bloebaum, R.D.2
  • 57
    • 0028297654 scopus 로고
    • Failure mechanisms in human vertebral cancellous bone
    • Fyhrie D.P., and Schaffler M.B. Failure mechanisms in human vertebral cancellous bone. Bone 15 1 (1994) 105-109
    • (1994) Bone , vol.15 , Issue.1 , pp. 105-109
    • Fyhrie, D.P.1    Schaffler, M.B.2
  • 58
    • 0031441779 scopus 로고    scopus 로고
    • Trabecular bone volume and microdamage accumulation in the femoral heads of women with and without femoral neck fractures
    • Mori S., Harruff R., Ambrosius W., and Burr D.B. Trabecular bone volume and microdamage accumulation in the femoral heads of women with and without femoral neck fractures. Bone 21 6 (1997) 521-526
    • (1997) Bone , vol.21 , Issue.6 , pp. 521-526
    • Mori, S.1    Harruff, R.2    Ambrosius, W.3    Burr, D.B.4
  • 59
    • 0028377564 scopus 로고
    • The extent of microcracking and the morphology of microcracks in damaged bone
    • Zioupos P., and Currey J.D. The extent of microcracking and the morphology of microcracks in damaged bone. J. Mater. Sci. 29 (1994) 978-986
    • (1994) J. Mater. Sci. , vol.29 , pp. 978-986
    • Zioupos, P.1    Currey, J.D.2
  • 60
    • 34547945278 scopus 로고    scopus 로고
    • Scanning and transmission electron microscopy for evaluation of order/disorder in bone structure
    • Suvorova E.I., Petrenko P.P., and Buffat P.A. Scanning and transmission electron microscopy for evaluation of order/disorder in bone structure. Scanning 29 4 (2007) 162-170
    • (2007) Scanning , vol.29 , Issue.4 , pp. 162-170
    • Suvorova, E.I.1    Petrenko, P.P.2    Buffat, P.A.3
  • 61
    • 0021761489 scopus 로고
    • Effects of differences in mineralization on the mechanical properties of bone
    • Currey J.D. Effects of differences in mineralization on the mechanical properties of bone. Philos. Trans. R. Soc. Lond. B Biol. Sci. 304 (1984) 509-518
    • (1984) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.304 , pp. 509-518
    • Currey, J.D.1
  • 62
    • 44649090086 scopus 로고    scopus 로고
    • Role of collagen and other organics in the mechanical properties of bone
    • Currey J.D. Role of collagen and other organics in the mechanical properties of bone. Osteoporos. Int. 14 Suppl. 5 (2003) 29-36
    • (2003) Osteoporos. Int. , vol.14 , Issue.SUPPL. 5 , pp. 29-36
    • Currey, J.D.1
  • 63
    • 4043114822 scopus 로고    scopus 로고
    • Structure and mechanical quality of the collagen-mineral nano-composite in bone
    • Fratzl P., Gupta H.S., Paschalis E.P., and Roschger P. Structure and mechanical quality of the collagen-mineral nano-composite in bone. J. Mater. Chem. 14 (2004) 2115-2123
    • (2004) J. Mater. Chem. , vol.14 , pp. 2115-2123
    • Fratzl, P.1    Gupta, H.S.2    Paschalis, E.P.3    Roschger, P.4
  • 64
    • 1542346348 scopus 로고    scopus 로고
    • Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone
    • Akkus O., Adar F., and Schaffler M.B. Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone. Bone 34 3 (2004) 443-453
    • (2004) Bone , vol.34 , Issue.3 , pp. 443-453
    • Akkus, O.1    Adar, F.2    Schaffler, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.