The use of self-interaction chromatography in stable formulation and crystallization of proteins

Biotechnology Journal

Volumn 4, Issue 9, 2009, Pages 1266-1277

  Deshpande, Kedar S ^a,b   Ahamed, Tangir ^a,c   ter Hoorst, Joop H ^b   Jansens, Peter J ^b   van der Wielen, Luuk A M ^a   Ottens, Marcel ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c SynCo Bio Partners   (Netherlands)

Author keywords

Miniaturization; Predictive protein crystallization; Protein phase behavior; Self interaction chromatography

Indexed keywords

BASIC PRINCIPLES; EXPERIMENTAL PROTOCOLS; MICRO-SCALES; MINIATURIZATION; NOVEL TECHNIQUES; PREDICTIVE PROTEIN CRYSTALLIZATION; PROTEIN CRYSTALLIZATION; PROTEIN SOLUTION; RATIONAL DESIGN; SELF-INTERACTION CHROMATOGRAPHIES; SELF-INTERACTION CHROMATOGRAPHY; SOLUTION CONDITIONS; THERAPEUTIC PROTEIN;

CHROMATOGRAPHIC ANALYSIS; CRYSTALLIZATION; MINIATURE INSTRUMENTS; PROTEINS; WAVE INTERFERENCE;

CHROMATOGRAPHY;

CHROMATOGRAPHY; COLUMN CHROMATOGRAPHY; COMPUTER SYSTEM; CRYSTALLIZATION; GEL PERMEATION CHROMATOGRAPHY; LIGHT SCATTERING; LIQUID CHROMATOGRAPHY; MICROFLUIDIC ANALYSIS; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS TECHNOLOGY; PROTEIN AGGREGATION; PROTEIN DETERMINATION; PROTEIN IMMOBILIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REVIEW; SELF INTERACTION CHROMATOGRAPHY;

CHROMATOGRAPHY; CRYSTALLIZATION; PROTEIN CONFORMATION; PROTEINS;

EID: 70350089358     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.200800226     Document Type: Review

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