Conserved polar residues stabilize transmembrane domains and promote oligomerization in human nucleoside triphosphate diphosphohydrolase 3

Biochemistry

Volumn 48, Issue 40, 2009, Pages 9437-9447

  Gaddie, Keith J ^a   Kirley, Terence L ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP-ASE ACTIVITY; C-TERMINUS; CONSERVED POLAR RESIDUES; ENZYMATIC ACTIVITIES; EXPRESSION LEVELS; HIGHER ORDER; HYDROGEN BOND INTERACTION; INTERMOLECULAR INTERACTIONS; INTRAMOLECULAR ASSOCIATION; INTRAMOLECULAR HYDROGEN BOND; LINKING STRATEGY; MUTANT PROTEINS; N-TERMINALS; POLAR RESIDUES; PROTEIN EXPRESSIONS; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE HELICES; TRIPHOSPHATE; TRITON X-100; TWEEN-20;

ACTIVATION ANALYSIS; BINDING SITES; BIOLOGICAL MEMBRANES; BIOMOLECULES; CALCIUM; CELL MEMBRANES; DETERGENTS; HYDROGEN; HYDROGEN BONDS; OLIGOMERIZATION; OLIGOMERS;

ASSOCIATION REACTIONS;

ADENOSINE TRIPHOSPHATASE (MAGNESIUM); CYSTEINE; MUTANT PROTEIN; NUCLEOSIDE TRIPHOSPHATE; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3; NUCLEOTIDASE; OLIGOMER; PHOSPHATASE; POLYSORBATE 20; TRITON X 100; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; ENZYME ACTIVITY; GLYCOSYLATION; HUMAN; HYDROGEN BOND; MOLECULAR INTERACTION; MUTATION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; HUMANS; MEMBRANE PROTEINS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PYROPHOSPHATASES; SEQUENCE ALIGNMENT;

EID: 70350041315     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900909g     Document Type: Article

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