Hydrodynamics-based transfection of pancreatic duodenal homeobox 1 DNA improves hyperglycemia and is associated with limited complications in diabetic mice

Endocrine Journal

Volumn 56, Issue 6, 2009, Pages 783-790

  Chen, Tsung Hsing ^a,b   Yeh, Chau Ting ^a,b   Ho, Yu Pin ^a,b   Hsu, Chen Ming ^a,b   Huang, Chau Chun ^a   Shiau, Shuen Shian ^a,b   Liang, Chun Kai ^a,b   Chang, Ming Ling ^a,b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Diabetic; Hepatic inflammation; Hydrodynamics based transfection (HBT); Pancreatic duodenal homeobox 1 (Pdx1); Streptozocin

Indexed keywords

ALANINE AMINOTRANSFERASE; COMPLEMENTARY DNA; DNA; INSULIN; TRANSCRIPTION FACTOR PDX 1;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; HYDRODYNAMICS BASED TRANSFECTION; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INFLAMMATION; LIVER; LIVER BIOPSY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEOTIDE SEQUENCE; PLASMID; POLYMERASE CHAIN REACTION; PROGNOSIS; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; CELL LINE, TUMOR; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; GENE THERAPY; HEMODYNAMICS; HOMEODOMAIN PROTEINS; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; LIVER; LIVER FUNCTION TESTS; MALE; MICE; PANCREAS; PLASMIDS; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 70349939612     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K09E-112     Document Type: Article

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