Mechanisms of U46619-induced contraction of rat pulmonary arteries in the presence and absence of the endothelium

British Journal of Pharmacology

Volumn 157, Issue 4, 2009, Pages 581-596

  McKenzie, C ^a   MacDonald, A ^a   Shaw, A M ^a  

^a GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

Author keywords

Chloride channels; Endothelium; Potassium channels; Rat pulmonary arteries; Rho kinase; Store operated calcium channels; Thromboxane A 2; U46619; Voltage operated calcium channels

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 AMINOETHOXYDIPHENYLBORANE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; CALCIUM CHANNEL BLOCKING AGENT; CARBON DIOXIDE; CHLORIDE CHANNEL BLOCKING AGENT; G PROTEIN COUPLED RECEPTOR; MIBEFRADIL; NIFEDIPINE; NIFLUMIC ACID; OXYGEN; PHOSPHOLIPASE C; POTASSIUM CHANNEL; RHO KINASE; CALCIUM CHANNEL; CHLORIDE CHANNEL; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; NITRIC OXIDE; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THROMBOXANE A2; THROMBOXANE RECEPTOR; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; MALE; MUSCLE ISOMETRIC CONTRACTION; MUSCLE TONE; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; DRUG POTENTIATION; IN VITRO STUDY; PATHOLOGY; PHYSIOLOGY; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; WISTAR RAT;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CHLORIDE CHANNELS; DRUG INTERACTIONS; ENDOTHELIUM, VASCULAR; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; NITRIC OXIDE; POTASSIUM CHANNEL BLOCKERS; PROSTAGLANDIN ANTAGONISTS; PULMONARY ARTERY; RATS; RATS, WISTAR; RECEPTORS, THROMBOXANE; RHO-ASSOCIATED KINASES; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THROMBOXANE A2; TYPE C PHOSPHOLIPASES; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 70349929386     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2008.00084.x     Document Type: Article

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