Advanced osteoarthritis in humans is associated with altered collagen VI expression and upregulation of ER-stress markers Grp78 and Bag-1

Journal of Histochemistry and Cytochemistry

Volumn 57, Issue 10, 2009, Pages 923-931

  Nugent, Ashleigh E ^a,b   Speicher, Danielle M ^a,b   Gradisar, Ian ^c   McBurney, Denise L ^a   Baraga, Anthony ^a   Doane, Kathleen J ^a   Horton Jr , Walter E ^a,b  

^a NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^b KENT STATE UNIVERSITY   (United States)

^c SUMMA HEALTH SYSTEM   (United States)

Author keywords

Bag 1; Cartilage; Collagen VI; ER stress; Grp78; NG2; Osteoarthritis

Indexed keywords

BAG 1 PROTEIN; COLLAGEN TYPE 6; GLUCOSE REGULATED PROTEIN 78; INTEGRIN RECEPTOR; PROTEIN NG2; UNCLASSIFIED DRUG; ANTIGEN; BCL2 ASSOCIATED ATHANOGENE 1 PROTEIN; BCL2-ASSOCIATED ATHANOGENE 1 PROTEIN; BIOLOGICAL MARKER; CHONDROITIN SULFATE PROTEOGLYCAN 4; DNA BINDING PROTEIN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PROTEOGLYCAN; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CANCER SURGERY; CARTILAGE MATRIX; CELL STRESS; CHONDROSARCOMA; CONTROLLED STUDY; DISEASE SEVERITY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; OSTEOARTHRITIS; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOTAL KNEE REPLACEMENT; UPREGULATION; BIOSYNTHESIS; BONE TUMOR; COMPARATIVE STUDY; DOWN REGULATION; KNEE OSTEOARTHRITIS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; ANTIGENS; BIOLOGICAL MARKERS; BONE NEOPLASMS; CARTILAGE, ARTICULAR; CHONDROSARCOMA; COLLAGEN TYPE VI; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HUMANS; MIDDLE AGED; OSTEOARTHRITIS, KNEE; OSTEOSARCOMA; PROTEOGLYCANS; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 70349908409     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.2009.953893     Document Type: Article

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