Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes

Matrix Biology

Volumn 17, Issue 8-9, 1998, Pages 625-633

  Hecht, Jacqueline T ^a   Montufar Solis, Dina ^b   Decker, Glen ^c   Lawler, Jack ^d   Daniels, Karla ^e   Duke, P Jackie ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c Cell and Molec Microscopy Services   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e UNIVERSITY OF IOWA   (United States)

Author keywords

Cartilage oligomeric matrix protein; Chondrocyte; COMP; Protein secretion; PSACH; Pseudoachondroplasia

Indexed keywords

CARTILAGE OLIGOMERIC MATRIX PROTEIN; MUTANT PROTEIN; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARTILAGE CELL; CELL DEATH; CELL DIFFERENTIATION; CELL STRUCTURE; CHONDRODYSPLASIA; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; ROUGH ENDOPLASMIC RETICULUM;

EID: 0032432979     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(98)90113-5     Document Type: Article

References (20)

1. Adams, J.C., Tucker, R.P. and Lawler, J.: The Thrombospondin Gene Family. R.G. Landis, Austin, 1995.
2. Briggs, M.D., Hoffman, S.M.G., King, L.M., Olsen, A.S., Mohrenweiser, H., Leroy, J.G., Mortier, G.R., Rimoin, D.L., Lachman, R.S., Gaines, E.S., Cekleniak, J.A., Knowlton, R.G. and Cohn, D.H.: Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene. Nat. Genet. 10: 330-336, 1995.
3. Briggs, M.D., Mortier, G.R, Cole, W.G., King, L.M., Olsen, A.S., Golik, S.S., Bonaventure J., Nuytinck L., DePaepe A., Leroy, J.G., Biesecker L., Lipson, M., Wilcox W.R., Lachman, R.S., Rimoin, D.L, Knowlton, R.G. and Cohn, D.H.: Diverse mutations in the gene for cartilage oligomeric matrix protein in Pseudoachondroplasia - Multiple Epiphyseal Dysplasia spectrum. Am. J. Hum. Genet. 62: 311-319, 1995.
4. Chen, H., Hecht, J.T. and Lawler, J.: A mutation in type 3 repeats of cartilage oligomeric matrix protein causes conformational changes. Am. Soc. Cell Biol. A323, 1997.
5. Chomczynski, P. and Sacci, N.: Single step method of RNA isolation by acid guanidium thiocyanate phenol chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
6. Cooper, R.R., Poinsetti, I.V. and Maynard, J.A.: A rough surfaced endoplasmic reticulum storage disorder. J. Bone Joint Surg. 55A: 475-484, 1973.
7. DiCesare, P.E., Hauser, N., Lehman, D., Pasumarti, S. and Paulsson, M.: Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon. FEBS Lett. 354: 237-240, 1994.
8. Ekman, S., Reinholt, F.P., Hultnby, K. and Heinegård, D.: Ultrastructural immunolocalization of catilage oligomeric matrix protein (COMP) in procine growth cartilage. Calcif. Tissue Int. 60: 547-553, 1997.
9. Hauselmann, H.J., Aydelotte, M.B., Kuettner, K.E., Gitelis, S.H. and Thonar, E.J.M.A.: Synthesis and turnover of proteoglycans by human and bovine articular chondrocytes cultured in alginate beads. Matrix 12: 116-129, 1992.
10. Hecht, J.T., Deere, M., Putnam, E., Cole, W., Vertel, B. and Lawler, J.: Characterization of cartilage oligomeric matrix protein (COMP) in normal and Pseudaochondroplasia musculoskeletal tissues. Matrix Biol., in press, 1998.
11. Hecht, J.T, Nelson. L.D., Crowder, E., Wang, Y., Elder, F.F.B., Harrison, W.R., Francomano, C.A., Prange, C.K., Lennon, G.G., Deere, M. and Lawler, J.: Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia. Nat. Genet. 10: 325-329, 1995.
12. Hedbom, E., Antonsson, P., Hjerpe, A., Aeschlimann, D., Paulsson, M., Rosa-Pimentel, E., Sommarin, Y., Wendel, M., Oldberg, A. and Heinegård, D.: Cartilage matrix proteins: An acidic oligomeric protein (COMP) detected in cartilage. J. Biol. Chem. 267: 6132-6136, 1992.
13. + binding and conformation. Am. Soc. Human Gen. Abstract 1002, 1997.
14. Maddox, B.K., Keene, D.R., Sakai, L.Y., Charbonneau, N.L., Morris, N.P., Boswell, B.A., Sussman, M., Horton, W.A., Bächinger, H.P. and Hecht, J.T.: The fate of COMP is determined by the cell type in the case of a novel mutation in PSACH. J. Biol. Chem. 272: 30993-30997, 1997.
15. McKeand, J., Rotta J. and Hecht, J.T.: Natural history study of pseudaochondroplasia. Am. J. Med. Genet. 62: 406-410, 1996.
16. Newton, G, Weremowicz, S., Morton, C.C., Copeland, N.G., Gilbert, D.J., Jenkins, N.A. and Lawler, J.: Characterization of human and mouse cartilage oligomeric matrix protein. Genomics 24: 435-439, 1994.
17. Palmoski, M., Perricone, E. and Brandt, K.D.: Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization. Arthritis Rheum. 22:508-517, 1979.
18. Petrov, P., Ouyang, Q. and Swinney H.L.: Resonant pattern formation in a chemical system. Nature 388: 655-657, 1997.
19. Prabakaran, D., Kim, P.S., Dixit, V.M. and Arvan, P.: Oligomeric assembly of thrombospondin in the endoplasmic reticulum of thyroid epithelial cells. Eur. J. Cell Biol. 70: 134-141, 1996.
20. Stanescu, V., Maroteaux, P. and Stanescu, R.: The biochemical defect of pseudoachondroplasia. Eur. J. Pediatr. 138: 221-225, 1982.