Prediction of enzyme classes from 3D structure: A general model and examples of experimental-theoretic scoring of peptide mass fingerprints of Leishmania proteins

Journal of Proteome Research

Volumn 8, Issue 9, 2009, Pages 4372-4382

  Concu, Riccardo ^a,b   Dea Ayuela, Maria A ^c   Perez Montoto, Lazaro G ^a   Bolas Fernández, Francisco ^d   Prado Prado, Francisco J ^a   Podda, Gianni ^b   Uriarte, Eugenio ^a   Ubeira, Florencio M ^a   González Díaz, Humberto ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNICA   (Italy)

^c UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

2D electrophoresis; Electrostatic potential; Enzyme mechanism of action; HINT potential; Leishmania infantum; Markov models; Mass spectrometry; Peptide mass fingerprints; Protein structure function relationship; QSAR

Indexed keywords

HYDROLASE; ISOMERASE; LIGASE; LYASE; OXIDOREDUCTASE; TRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM IDENTIFICATION; CONTROLLED STUDY; DNA FINGERPRINTING; ENZYME ANALYSIS; ENZYME MECHANISM; LEISHMANIA; LEISHMANIA INFANTUM; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL GENETICS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR DYNAMICS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROBABILITY; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THEORETICAL MODEL; THREE DIMENSIONAL IMAGING; TWO DIMENSIONAL ELECTROPHORESIS;

ALGORITHMS; ANIMALS; DATABASES, PROTEIN; DISCRIMINANT ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYMES; LEISHMANIA INFANTUM; MODELS, MOLECULAR; PEPTIDE MAPPING; PROTEIN CONFORMATION; PROTOZOAN PROTEINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EUKARYOTA; LEISHMANIA INFANTUM; PROKARYOTA;

EID: 70349895744     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr9003163     Document Type: Article

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