Preparation and validation of radio iodinated recombinant human IL-10 for the measurement of natural human antibodies against IL-10

Journal of Immunological Methods

Volumn 350, Issue 1-2, 2009, Pages 46-53

  de Lemos Rieper, Carina ^a,b   Galle, Pia ^b   Svenson, Morten ^a   Pedersen, Bente Klarlund ^b   Hansen, Morten Bagge ^a  

^a University of Copenhagen   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Autoantibodies; Autoimmunity; IL 10; Immunologic tolerance; Natural antibodies

Indexed keywords

IMMUNOGLOBULIN G; INTERLEUKIN 10 ANTIBODY; IODINE 125; RECOMBINANT INTERLEUKIN 10; STAT3 PROTEIN;

ANTIBODY DETECTION; ANTIGEN BINDING; ARTICLE; BLOOD SAMPLING; COLUMN CHROMATOGRAPHY; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIOIMMUNOASSAY; RADIOIODINATION;

ANIMALS; AUTOANTIBODIES; BLOOD DONORS; CHO CELLS; CRICETINAE; CRICETULUS; DONOR SELECTION; HUMANS; INFLAMMATION; INTERLEUKIN-10; IODINE ISOTOPES; RADIOIMMUNOASSAY; RECOMBINANT PROTEINS;

EID: 70349804671     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2009.07.005     Document Type: Article

References (23)

1. Antonelli G., Simeoni E., Currenti M., De P.F., Colizzi V., Pistello M., and Dianzani F. Interferon antibodies in patients with infectious diseases. Anti-interferon antibodies. Biotherapy 10 (1997) 7
2. Bendtzen K., Hansen M.B., Ross C., and Svenson M. High-avidity autoantibodies to cytokines. Immunol. Today 19 (1998) 209
3. Bendtzen K., Hansen M.B., Ross C., and Svenson M. Detection of autoantibodies to cytokines. Mol. Biotechnol. 14 (2000) 251
4. Bonfield T.L., Russell D., Burgess S., Malur A., Kavuru M.S., and Thomassen M.J. Autoantibodies against granulocyte macrophage colony-stimulating factor are diagnostic for pulmonary alveolar proteinosis. Am. J. Respir. Cell Mol. Biol. 27 (2002) 481
5. Couper K.N., Blount D.G., and Riley E.M. IL-10: the master regulator of immunity to infection. J. Immunol. 180 (2008) 5771
6. Galle P., Svenson M., Bendtzen K., and Hansen M.B. High levels of neutralizing IL-6 autoantibodies in 0.1% of apparently healthy blood donors. Eur. J. Immunol. 34 (2004) 3267
7. Hansen M.B., Svenson M., and Bendtzen K. Serum-induced suppression of interferon (IFN) activity. Lack of evidence for the presence of specific autoantibodies to IFN-alpha in normal human sera. Clin. Exp. Immunol. 88 (1992) 559
8. Hansen M.B., Svenson M., Abell K., Yasukawa K., Diamant M., and Bendtzen K. Influence of interleukin-6 (IL-6) autoantibodies on IL-6 binding to cellular receptors. Eur. J. Immunol. 25 (1995) 348
9. Hoflich C., Sabat R., Rosseau S., Temmesfeld B., Slevogt H., Docke W.D., Grutz G., Meisel C., Halle E., Gobel U.B., Volk H.D., and Suttorp N. Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. Blood 103 (2004) 673
10. Liu E., and Eisenbarth G.S. Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays. Clin. Immunol. 125 (2007) 120
11. Meager A., Visvalingam K., Peterson P., Moll K., Murumagi A., Krohn K., Eskelin P., Perheentupa J., Husebye E., Kadota Y., and Willcox N. Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS. Med. 3 (2006) e289
12. Menetrier-Caux C., Briere F., Jouvenne P., Peyron E., Peyron F., and Banchereau J. Identification of human IgG autoantibodies specific for IL-10. Clin. Exp. Immunol. 104 (1996) 173
13. Murray P.J. Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response. Curr. Opin. Pharmacol. 6 (2006) 379
14. Puel A., Picard C., Lorrot M., Pons C., Chrabieh M., Lorenzo L., Mamani-Matsuda M., Jouanguy E., Gendrel D., and Casanova J.L. Recurrent staphylococcal cellulitis and subcutaneous abscesses in a child with autoantibodies against IL-6. J. Immunol. 180 (2008) 647
15. Rieper C.dL., Galle P., and Hansen M.B. Characterization and potential clinical applications of autoantibodies against cytokines. Cytokine Growth Factor Rev. 20 (2009) 61
16. Spencer J.V., Cadaoas J., Castillo P.R., Saini V., and Slobedman B. Stimulation of B-lymphocytes by cmvIL-10 but not LAcmvIL-10. Virology 374 (2008) 164
17. Svenson M., Hansen M.B., Kayser L., Rasmussen A.K., Reimert C.M., and Bendtzen K. Effects of human anti-IL-1 alpha autoantibodies on receptor binding and biological activities of IL-1. Cytokine 4 (1992) 125
18. Svenson M., Hansen M.B., and Bendtzen K. Binding of cytokines to pharmaceutically prepared human immunoglobulin. J. Clin. Invest. 92 (1993) 2533
19. Svenson M., Hansen M.B., Ross C., Diamant M., Rieneck K., Nielsen H., and Bendtzen K. Antibody to granulocyte-macrophage colony-stimulating factor is a dominant anti-cytokine activity in human IgG preparations. Blood 91 (1998) 2054
20. Syto R., Murgolo N.J., Braswell E.H., Mui P., Huang E., and Windsor W.T. Structural and biological stability of the human interleukin 10 homodimer. Biochemistry 37 (1998) 16,943
21. Walter M.R., and Nagabhushan T.L. Crystal structure of interleukin 10 reveals and interferon gamma-like fold. Biochemistry 34 (1995) 12,118
22. Zdanov A. Structural features of the interleukin-10 family of cytokines. Curr. Pharm. Des. 10 (2004) 3873
23. Zdanov A., Schalk-Hihi C., Gustchina A., Tsang M., Weatherbee J., and Wlodawer A. Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma. Structure 3 (1995) 591