Stimulation of B lymphocytes by cmvIL-10 but not LAcmvIL-10

Virology

Volumn 374, Issue 1, 2008, Pages 164-169

  Spencer, Juliet V ^a   Cadaoas, Jaclyn ^a   Castillo, Patricia R ^a   Saini, Vandana ^a   Slobedman, Barry ^b  

^a UNIVERSITY OF SAN FRANCISCO   (United States)

^b WESTMEAD HOSPITAL   (Australia)

Author keywords

Human cytomegalovirus; Immune evasion; Interleukin 10; Viral cytokine

Indexed keywords

CYTOMEGALOVIRUS INTERLEUKIN 10; INTERLEUKIN 10; LATENCY ASSOCIATED CYTOMEGALOVIRUS INTERLEUKIN 10; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; VIRUS INFECTIVITY;

B-LYMPHOCYTES; CELL LINE; CELL PROLIFERATION; HUMANS; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; STAT3 TRANSCRIPTION FACTOR; VIRAL PROTEINS;

HUMAN HERPESVIRUS 5;

EID: 41149122453     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.11.031     Document Type: Article

References (21)

1. Basta S., and Bennink J.R. A survival game of hide and seek: cytomegaloviruses and MHC class I antigen presentation pathways. Viral. Immunol. 16 3 (2003) 231-242
2. Brennan D.C. Cytomegalovirus in renal transplantation. J. Am. Soc. Nephrol. 12 4 (2001) 848-855
3. Britt W.J.a., and C.A.A. Cytomegalovirus. In: Fields D.M.K.B.N., Howley P.M., et al. (Eds). Fields Virology. 3rd Edition (1996), Lippincott-Raven Publishers, Philadelphia, PA 2493-2523
4. Brooks D.G., Trifilo M.J., Edelmann K.H., Teyton L., McGavern D.B., and Oldstone M.B. Interleukin-10 determines viral clearance or persistence in vivo. Nat. Med. 12 11 (2006) 1301-1309
5. Chang W.L., Baumgarth N., Yu D., and Barry P.A. Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality. J. Virol. 78 16 (2004) 8720-8731
6. Fleming S.B., McCaughan C.A., Andrews A.E., Nash A.D., and Mercer A.A. A homolog of interleukin-10 is encoded by the poxvirus Orf virus. J. Virol. 71 6 (1997) 4857-4861
7. Go N.F., Castle B.E., Barrett R., Kastelein R., Dang W., Mosmann T.R., Moore K.W., and Howard M. Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J. Exp. Med. 172 6 (1990) 1625-16231
8. Hengel H., Brune W., and Koszinowski U.H. Immune evasion by cytomegalovirus-survival strategies of a highly adapted opportunist. Trends Microbiol. 6 5 (1998) 190-197
9. Hsu D.H., de Waal Malefyt R., Fiorentino D.F., Dang M.N., Vieira P., de Vries J., Spits H., Mosmann T.R., and Moore K.W. Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science 250 4982 (1990) 830-832
10. Jenkins C., Abendroth A., and Slobedman B. A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection. J. Virol. 78 3 (2004) 1440-1447
11. Jones B.C., Logsdon N.J., Josephson K., Cook J., Barry P.A., and Walter M.R. Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc. Natl. Acad. Sci. U. S. A. 99 14 (2002) 9404-9409
12. Kotenko S.V., Saccani S., Izotova L.S., Mirochnitchenko O.V., and Pestka S. Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10). Proc. Natl Acad. Sci. U. S. A. 97 4 (2000) 1695-1700
13. Mocarski Jr. E.S. Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion. Trends Microbiol. 10 7 (2002) 332-339
14. Moore K.W., de Waal Malefyt R., Coffman R.L., and O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19 (2001) 683-765
15. Murphy E., Yu D., Grimwood J., Schmutz J., Dickson M., Jarvis M.A., Hahn G., Nelson J.A., Myers R.M., and Shenk T.E. Coding potential of laboratory and clinical strains of human cytomegalovirus. Proc. Natl. Acad. Sci. U. S. A. 100 25 (2003) 14976-14981
16. Raftery M.J., Wieland D., Gronewald S., Kraus A.A., Giese T., and Schonrich G. Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10. J. Immunol. 173 5 (2004) 3383-3391
17. Redpath S., Ghazal P., and Gascoigne N.R. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol. 9 2 (2001) 86-92
18. Rode H.J., Janssen W., Rosen-Wolff A., Bugert J.J., Thein P., Becker Y., and Darai G. The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene. Virus Genes 7 1 (1993) 111-116
19. Rousset F., Garcia E., Defrance T., Peronne C., Vezzio N., Hsu D.H., Kastelein R., Moore K.W., and Banchereau J. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 89 5) (1992) 1890-1893
20. Spencer J.V. The cytomegalovirus homolog of interleukin-10 requires phosphatidylinositol 3-kinase activity for inhibition of cytokine synthesis in monocytes. J. Virol. 81 4 (2007) 2083-2086
21. Spencer J.V., Lockridge K.M., Barry P.A., Lin G., Tsang M., Penfold M.E., and Schall T.J. Potent immunosuppressive activities of cytomegalovirus-encoded interleukin-10. J. Virol. 76 3 (2002) 1285-1292