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Volumn 126, Issue 1, 2009, Pages 127-133

No effect of acute, single dose oral administration of Momordica charantia Linn., on glycemia, energy expenditure and appetite: A pilot study in non-diabetic overweight men

Author keywords

Appetite; Energy expenditure; Humans; Hunger; Momordica charantia Linn.; Obesity; Phytomedicine; Visual analogue scale

Indexed keywords

CARBOHYDRATE; GLUCOSE; INSULIN; LIPID; MOMORDICA CHARANTIA EXTRACT; PLACEBO;

EID: 70349786477     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.07.035     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 0033107711 scopus 로고    scopus 로고
    • Effect of Momordica charantia (karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients
    • Ahmad N., Hassan M.R., Halder H., and Bennoor K.S. Effect of Momordica charantia (karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients. Bangladesh Medical Research Council Bulletin 25 (1999) 11-13
    • (1999) Bangladesh Medical Research Council Bulletin , vol.25 , pp. 11-13
    • Ahmad, N.1    Hassan, M.R.2    Halder, H.3    Bennoor, K.S.4
  • 2
    • 3442899940 scopus 로고    scopus 로고
    • Beneficial effects and mechanism of action of Momordica charantia juice in the treatment of streptozotocin-induced diabetes mellitus in rat
    • Ahmed I., Adeghate E., Cummings E., Sharma A.K., and Singh J. Beneficial effects and mechanism of action of Momordica charantia juice in the treatment of streptozotocin-induced diabetes mellitus in rat. Molecular and Cellular Biochemistry 261 (2004) 63-70
    • (2004) Molecular and Cellular Biochemistry , vol.261 , pp. 63-70
    • Ahmed, I.1    Adeghate, E.2    Cummings, E.3    Sharma, A.K.4    Singh, J.5
  • 3
    • 0032104490 scopus 로고    scopus 로고
    • Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat
    • Ahmed I., Adeghate E., Sharma A.K., Pallot D.J., and Singh J. Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat. Diabetes Research and Clinical Practice 40 (1998) 145-151
    • (1998) Diabetes Research and Clinical Practice , vol.40 , pp. 145-151
    • Ahmed, I.1    Adeghate, E.2    Sharma, A.K.3    Pallot, D.J.4    Singh, J.5
  • 4
    • 0019943438 scopus 로고
    • Trial of Momordica charantia Linn. (Karela) powder in patients with maturity-onset diabetes
    • Akhtar M.S. Trial of Momordica charantia Linn. (Karela) powder in patients with maturity-onset diabetes. Journal of Pakistan Medical Association 32 (1982) 106-107
    • (1982) Journal of Pakistan Medical Association , vol.32 , pp. 106-107
    • Akhtar, M.S.1
  • 5
    • 0027373553 scopus 로고
    • Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordica charantia on normal and diabetic model rats
    • Ali L., Azad Khan A.K., Rouf Mamun M.I., Mosihuzzaman M., Nahar N., Nur-e-Alam M., et al. Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordica charantia on normal and diabetic model rats. Planta Medica 59 (1993) 408-412
    • (1993) Planta Medica , vol.59 , pp. 408-412
    • Ali, L.1    Azad Khan, A.K.2    Rouf Mamun, M.I.3    Mosihuzzaman, M.4    Nahar, N.5    Nur-e-Alam, M.6
  • 6
    • 9644280963 scopus 로고    scopus 로고
    • Ethnomedicinal uses of momordicacharantia (cucurbitaceae) in togo and relation to its phytochemistry and biological activity
    • Beloin N., Gbeassor M., Akpagana K., Hudson J., de Soussa K., Koumaglo K., et al. Ethnomedicinal uses of momordicacharantia (cucurbitaceae) in togo and relation to its phytochemistry and biological activity. Journal of Ethnopharmacology 96 (2005) 49-55
    • (2005) Journal of Ethnopharmacology , vol.96 , pp. 49-55
    • Beloin, N.1    Gbeassor, M.2    Akpagana, K.3    Hudson, J.4    de Soussa, K.5    Koumaglo, K.6
  • 7
    • 0022626574 scopus 로고
    • Paradoxical effects of an intense sweetener (aspartame) on appetite
    • Blundell J.E., and Hill A.J. Paradoxical effects of an intense sweetener (aspartame) on appetite. Lancet 1 (1986) 1092-1093
    • (1986) Lancet , vol.1 , pp. 1092-1093
    • Blundell, J.E.1    Hill, A.J.2
  • 8
    • 0028110340 scopus 로고
    • Hypoglycaemic effect of Momordica charantia extracts in normoglycaemic or cyproheptadine-induced hyperglycaemic mice
    • Cakici I., Hurmoglu C., Tunctan B., Abacioglu N., Kanzik I., and Sener B. Hypoglycaemic effect of Momordica charantia extracts in normoglycaemic or cyproheptadine-induced hyperglycaemic mice. Journal of Ethnopharmacology 44 (1994) 117-121
    • (1994) Journal of Ethnopharmacology , vol.44 , pp. 117-121
    • Cakici, I.1    Hurmoglu, C.2    Tunctan, B.3    Abacioglu, N.4    Kanzik, I.5    Sener, B.6
  • 9
    • 0037385896 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia) reduces adiposity, lowers serum insulin and normalizes glucose tolerance in rats fed a high fat diet
    • Chen Q., Chan L.L., and Li E.T. Bitter melon (Momordica charantia) reduces adiposity, lowers serum insulin and normalizes glucose tolerance in rats fed a high fat diet. Journal of Nutrition 133 (2003) 1088-1093
    • (2003) Journal of Nutrition , vol.133 , pp. 1088-1093
    • Chen, Q.1    Chan, L.L.2    Li, E.T.3
  • 10
    • 24344453383 scopus 로고    scopus 로고
    • Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines
    • Chen Q., and Li E.T. Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines. British Journal of Nutrition 93 (2005) 747-754
    • (2005) British Journal of Nutrition , vol.93 , pp. 747-754
    • Chen, Q.1    Li, E.T.2
  • 11
    • 24344453383 scopus 로고    scopus 로고
    • Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines
    • Chen Q., and Li E.T. Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines. The British Journal of Nutrition 93 (2005) 747-754
    • (2005) The British Journal of Nutrition , vol.93 , pp. 747-754
    • Chen, Q.1    Li, E.T.2
  • 12
    • 24344453383 scopus 로고    scopus 로고
    • Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines
    • Chen Q., and Li E.T.S. Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamines. British Journal of Nutrition 93 (2005) 747-754
    • (2005) British Journal of Nutrition , vol.93 , pp. 747-754
    • Chen, Q.1    Li, E.T.S.2
  • 15
    • 38049123030 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats
    • Huang H.-, Hong Y.-, Wong Y.-, Chen Y.-, Chyuan J.-, Huang C.-, et al. Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats. British Journal of Nutrition 99 (2008) 230-239
    • (2008) British Journal of Nutrition , vol.99 , pp. 230-239
    • Huang H.-1    Hong Y.-2    Wong Y.-3    Chen Y.-4    Chyuan J.-5    Huang C.-6
  • 17
    • 33746386763 scopus 로고    scopus 로고
    • Bitter gourd (Momordica charantia): a dietary approach to hyperglycemia
    • Krawinkel M.B., and Keding G.B. Bitter gourd (Momordica charantia): a dietary approach to hyperglycemia. Nutrition Reviews 64 (2006) 331-337
    • (2006) Nutrition Reviews , vol.64 , pp. 331-337
    • Krawinkel, M.B.1    Keding, G.B.2
  • 19
    • 23944448055 scopus 로고    scopus 로고
    • Bitter gourd (Momordica charantia) modulates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats
    • Kumar Shetty A., Suresh Kumar G., and Veerayya Salimath P. Bitter gourd (Momordica charantia) modulates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats. Molecular Nutrition and Research 49 (2005) 791-796
    • (2005) Molecular Nutrition and Research , vol.49 , pp. 791-796
    • Kumar Shetty, A.1    Suresh Kumar, G.2    Veerayya Salimath, P.3
  • 21
    • 70349783243 scopus 로고    scopus 로고
    • Phytochemicals isolated from the anti-hyperglycaemic hexane extracts of the unripe fruit of Momordica charantia L.
    • Lau C.R.A., Noel M., Kergoat M., and Autier V. Phytochemicals isolated from the anti-hyperglycaemic hexane extracts of the unripe fruit of Momordica charantia L. Journal of Pharmacy and Pharmacology 50 (1998) 84
    • (1998) Journal of Pharmacy and Pharmacology , vol.50 , pp. 84
    • Lau, C.R.A.1    Noel, M.2    Kergoat, M.3    Autier, V.4
  • 24
    • 13444277207 scopus 로고    scopus 로고
    • Momordica charantia extracts inhibit uptake of monosaccharide and amino acid across rat everted gut sacs in-vitro
    • Mahomoodally M.F., Fakim A.-, and Subratty A.H. Momordica charantia extracts inhibit uptake of monosaccharide and amino acid across rat everted gut sacs in-vitro. Biological and Pharmaceutical Bulletin 27 (2004) 216-218
    • (2004) Biological and Pharmaceutical Bulletin , vol.27 , pp. 216-218
    • Mahomoodally, M.F.1    Fakim A.-2    Subratty, A.H.3
  • 25
    • 13444292156 scopus 로고    scopus 로고
    • Experimental evidence for in vitro fluid transport in the presence of a traditional medicinal fruit extract across rat everted intestinal sacs
    • Mahomoodally M.F., Gurib-Fakim A., and Subratty A.H. Experimental evidence for in vitro fluid transport in the presence of a traditional medicinal fruit extract across rat everted intestinal sacs. Fundamental and Clinical Pharmacology 19 (2005) 87-92
    • (2005) Fundamental and Clinical Pharmacology , vol.19 , pp. 87-92
    • Mahomoodally, M.F.1    Gurib-Fakim, A.2    Subratty, A.H.3
  • 26
    • 0032955530 scopus 로고    scopus 로고
    • Inhibition of gastric emptying by triterpene saponin, momordin ic, in mice: Roles of blood glucose, capsaicinsensitive sensory nerves, and central nervous system
    • Matsuda H., Li Y., Yamahara J., and Yoshikawa M. Inhibition of gastric emptying by triterpene saponin, momordin ic, in mice: Roles of blood glucose, capsaicinsensitive sensory nerves, and central nervous system. Journal of Pharmacology and Experimental Therapeutics 289 (1999) 729-734
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.289 , pp. 729-734
    • Matsuda, H.1    Li, Y.2    Yamahara, J.3    Yoshikawa, M.4
  • 27
    • 0033522839 scopus 로고    scopus 로고
    • Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats
    • Matsuda H., Li Y., and Yoshikawa M. Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats. Life Sciences 65 (1999) 27-32
    • (1999) Life Sciences , vol.65 , pp. 27-32
    • Matsuda, H.1    Li, Y.2    Yoshikawa, M.3
  • 29
    • 16244401835 scopus 로고    scopus 로고
    • Suppressive activity of the fruit of Momordica charantia with exercise on blood glucose in type 2 diabetic mice
    • Miura T., Itoh Y., Iwamoto N., Kato M., and Ishida T. Suppressive activity of the fruit of Momordica charantia with exercise on blood glucose in type 2 diabetic mice. Biological and Pharmaceutical Bulletin 27 (2004) 248-250
    • (2004) Biological and Pharmaceutical Bulletin , vol.27 , pp. 248-250
    • Miura, T.1    Itoh, Y.2    Iwamoto, N.3    Kato, M.4    Ishida, T.5
  • 30
    • 0035144201 scopus 로고    scopus 로고
    • Medicinal foodstuffs. XXI. structures of new cucurbitane-type triterpene glycosides, goyaglycosides-a, -b, -c, -d, -e, -f, -g, and -h, and new oleanane-type triterpene saponins, goyasaponins I, II, and III, from the fresh fruit of japanese Momordica charantia L
    • Murakami T., Emoto A., Matsuda H., and Yoshikawa M. Medicinal foodstuffs. XXI. structures of new cucurbitane-type triterpene glycosides, goyaglycosides-a, -b, -c, -d, -e, -f, -g, and -h, and new oleanane-type triterpene saponins, goyasaponins I, II, and III, from the fresh fruit of japanese Momordica charantia L. Chemical and Pharmaceutical Bulletin 49 (2001) 54-63
    • (2001) Chemical and Pharmaceutical Bulletin , vol.49 , pp. 54-63
    • Murakami, T.1    Emoto, A.2    Matsuda, H.3    Yoshikawa, M.4
  • 31
    • 33845422623 scopus 로고    scopus 로고
    • Hypoglycemic effect of the seeds of Momordica charantia
    • Omar S.H., Ansari Z., and Nehal M. Hypoglycemic effect of the seeds of Momordica charantia. Fitoterapia 78 (2007) 46-47
    • (2007) Fitoterapia , vol.78 , pp. 46-47
    • Omar, S.H.1    Ansari, Z.2    Nehal, M.3
  • 32
    • 0036226097 scopus 로고    scopus 로고
    • Purification and characterization of charantin, a napin-like ribosome-inactivating peptide from bitter gourd (Momordica charantia) seeds
    • Parkash A., Ng T.B., and Tso W.W. Purification and characterization of charantin, a napin-like ribosome-inactivating peptide from bitter gourd (Momordica charantia) seeds. Journal of Peptide Research 59 (2002) 197-202
    • (2002) Journal of Peptide Research , vol.59 , pp. 197-202
    • Parkash, A.1    Ng, T.B.2    Tso, W.W.3
  • 33
    • 70349785125 scopus 로고    scopus 로고
    • Perronet F, M.D., 1991. Table of nonprotein respiratory quotient: an update. 16, 23-29.
    • Perronet F, M.D., 1991. Table of nonprotein respiratory quotient: an update. 16, 23-29.
  • 34
    • 0030034198 scopus 로고    scopus 로고
    • Determinants of postprandial appetite sensations: macronutrient intake and glucose metabolism
    • Raben A., Holst J.J., Christensen N.J., and Astrup A. Determinants of postprandial appetite sensations: macronutrient intake and glucose metabolism. International Journal of Obesity 20 (1996) 161-169
    • (1996) International Journal of Obesity , vol.20 , pp. 161-169
    • Raben, A.1    Holst, J.J.2    Christensen, N.J.3    Astrup, A.4
  • 35
    • 0035990605 scopus 로고    scopus 로고
    • The effect of Momordica charantia and mucuna pruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism
    • Rathi S.S., Grover J.K., and Vats V. The effect of Momordica charantia and mucuna pruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism. Phytotherapy Research 16 (2002) 236-243
    • (2002) Phytotherapy Research , vol.16 , pp. 236-243
    • Rathi, S.S.1    Grover, J.K.2    Vats, V.3
  • 36
    • 3242705191 scopus 로고    scopus 로고
    • Application of modified in vitro screening procedure for identifying herbals possessing sulfonylurea-like activity
    • Rotshteyn Y., and Zito S.W. Application of modified in vitro screening procedure for identifying herbals possessing sulfonylurea-like activity. Journal of Ethnopharmacology 93 (2004) 337-344
    • (2004) Journal of Ethnopharmacology , vol.93 , pp. 337-344
    • Rotshteyn, Y.1    Zito, S.W.2
  • 37
    • 21144434516 scopus 로고    scopus 로고
    • Beneficial effects of Momordica charantia seeds in the treatment of STZ-induced diabetes in experimental rats
    • Sathishsekar D., and Subramanian S. Beneficial effects of Momordica charantia seeds in the treatment of STZ-induced diabetes in experimental rats. Biological and Pharmaceutical Bulletin 28 (2005) 978-983
    • (2005) Biological and Pharmaceutical Bulletin , vol.28 , pp. 978-983
    • Sathishsekar, D.1    Subramanian, S.2
  • 39
    • 0027215565 scopus 로고
    • Hypoglycaemic activity of coccinia indica and Momordica charantia in diabetic rats: Depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase
    • Shibib B.A., Khan L.A., and Rahman R. Hypoglycaemic activity of coccinia indica and Momordica charantia in diabetic rats: Depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase. Biochemical Journal 292 (1993) 267-270
    • (1993) Biochemical Journal , vol.292 , pp. 267-270
    • Shibib, B.A.1    Khan, L.A.2    Rahman, R.3
  • 40
    • 40449117390 scopus 로고    scopus 로고
    • Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats
    • Sridhar M.G., Vinayagamoorthi R., Arul Suyambunathan V., Bobby Z., and Selvaraj N. Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats. British Journal of Nutrition 99 (2008) 806-812
    • (2008) British Journal of Nutrition , vol.99 , pp. 806-812
    • Sridhar, M.G.1    Vinayagamoorthi, R.2    Arul Suyambunathan, V.3    Bobby, Z.4    Selvaraj, N.5
  • 43
    • 0032501443 scopus 로고    scopus 로고
    • Ribosome inactivating protein and lectin from bitter melon (Momordica charantia) seeds: sequence comparison with related proteins
    • Wang H., and Ng T.B. Ribosome inactivating protein and lectin from bitter melon (Momordica charantia) seeds: sequence comparison with related proteins. Biochemistry and Biophysics Research Communication 253 (1998) 143-146
    • (1998) Biochemistry and Biophysics Research Communication , vol.253 , pp. 143-146
    • Wang, H.1    Ng, T.B.2
  • 45
    • 14244253087 scopus 로고    scopus 로고
    • Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats
    • Yadav U.C.S., Moorthy K., and Baquer N.Z. Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats. Molecular and Cellular Biochemistry 268 (2005) 111-120
    • (2005) Molecular and Cellular Biochemistry , vol.268 , pp. 111-120
    • Yadav, U.C.S.1    Moorthy, K.2    Baquer, N.Z.3
  • 46
    • 0042668497 scopus 로고    scopus 로고
    • Systematic review of herbs and dietary supplements for glycemic control in diabetes
    • Yeh G.Y., Eisenberg D.M., Kaptchuk T.J., and Phillips R.S. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 26 (2003) 1277-1294
    • (2003) Diabetes Care , vol.26 , pp. 1277-1294
    • Yeh, G.Y.1    Eisenberg, D.M.2    Kaptchuk, T.J.3    Phillips, R.S.4
  • 48
    • 38949083117 scopus 로고    scopus 로고
    • Hypoglycemic effect of semipurified peptides from Momordica charantia L. var. abbreviata ser. in alloxan-induced diabetic mice
    • Yuan X.-, Gu X.-, Tang J., and Wasswa J. Hypoglycemic effect of semipurified peptides from Momordica charantia L. var. abbreviata ser. in alloxan-induced diabetic mice. Journal of Food Biochemistry 32 (2008) 107-121
    • (2008) Journal of Food Biochemistry , vol.32 , pp. 107-121
    • Yuan X.-1    Gu X.-2    Tang, J.3    Wasswa, J.4


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