메뉴 건너뛰기




Volumn 17, Issue 7, 2009, Pages 491-495

Oral delivery of siRNA and antisense oligonucleotides

Author keywords

Gene silencing; GIT; Gut; M cells; Oligodeoxynucleotides; Oral drug delivery; Peyers patches; Short interfering RNA

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BETA 1,3 GLUCAN; SMALL INTERFERING RNA;

EID: 70349784215     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860903057674     Document Type: Note
Times cited : (51)

References (39)
  • 2
    • 59849090457 scopus 로고    scopus 로고
    • Cellular delivery in vivo of siRNA-based therapeutics
    • [Review]
    • Aigner A. (2008). Cellular delivery in vivo of siRNA-based therapeutics. Curr Pharm Des, 14(34), 3603-3619. [Review]
    • (2008) Curr Pharm des , vol.14 , Issue.34 , pp. 3603-3619
    • Aigner, A.1
  • 3
    • 33645982602 scopus 로고    scopus 로고
    • Non-viral vectors for gene therapy: Beyond delivery
    • Akhtar S. (2006). Non-viral vectors for gene therapy: beyond delivery. Gene Ther, 13, 739-740.
    • (2006) Gene Ther , vol.13 , pp. 739-740
    • Akhtar, S.1
  • 4
    • 36849044732 scopus 로고    scopus 로고
    • Nonviral delivery of synthetic siRNAs in vivo
    • December
    • Akhtar S, Benter IF. (2007a, December). Nonviral delivery of synthetic siRNAs in vivo. J Clin Invest, 117(12), 3623-3632.
    • (2007) J Clin Invest , vol.117 , Issue.12 , pp. 3623-3632
    • Akhtar, S.1    Benter, I.F.2
  • 5
    • 34248672837 scopus 로고    scopus 로고
    • Toxicogenomics of non-viral drug delivery systems for RNAi: Potential impact on siRNAmediated gene silencing activity and specificity
    • March 30
    • Akhtar S, Benter I. (2007b, March 30). Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNAmediated gene silencing activity and specificity. Adv Drug Deliv Rev, 59(2-3), 164-182.
    • (2007) Adv Drug Deliv Rev , vol.59 , Issue.2-3 , pp. 164-182
    • Akhtar, S.1    Benter, I.2
  • 7
    • 65949106130 scopus 로고    scopus 로고
    • Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation
    • April 30
    • Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. (2009, April 30). Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature, 458(7242), 1180-1184.
    • (2009) Nature , vol.458 , Issue.7242 , pp. 1180-1184
    • Aouadi, M.1    Tesz, G.J.2    Nicoloro, S.M.3    Wang, M.4    Chouinard, M.5    Soto, E.6    Ostroff, G.R.7    Czech, M.P.8
  • 8
    • 1842588051 scopus 로고    scopus 로고
    • Gene silencing nucleic acids designed by scanning arrays: Anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system
    • August
    • Beale G, Hollins AJ, Benboubetra M, Sohail M, Fox SP, Benter I, Akhtar S. (2003, August). Gene silencing nucleic acids designed by scanning arrays: anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system. J Drug Target, 11(7), 449-456.
    • (2003) J Drug Target , vol.11 , Issue.7 , pp. 449-456
    • Beale, G.1    Hollins, A.J.2    Benboubetra, M.3    Sohail, M.4    Fox, S.P.5    Benter, I.6    Akhtar, S.7
  • 10
    • 38149017208 scopus 로고    scopus 로고
    • M-cells: Origin, morphology and role in mucosal immunity and microbial pathogenesis
    • January
    • Corr SC, Gahan CC, Hill C. (2008, January). M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis. FEMS Immunol Med Microbiol, 52(1), 2-12.
    • (2008) FEMS Immunol Med Microbiol , vol.52 , Issue.1 , pp. 2-12
    • Corr, S.C.1    Gahan, C.C.2    Hill, C.3
  • 11
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Costanotto D, Rossi JJ. (2009). The promises and pitfalls of RNA- interference-based therapeutics. Nature, 457(7228), 426-433.
    • (2009) Nature , vol.457 , Issue.7228 , pp. 426-433
    • Costanotto, D.1    Rossi, J.J.2
  • 12
    • 55649089421 scopus 로고    scopus 로고
    • State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers
    • December 8
    • Fattal E, Bochot A. (2008, December 8). State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers. Int J Pharm, 364(2), 237-248.
    • (2008) Int J Pharm , vol.364 , Issue.2 , pp. 237-248
    • Fattal, E.1    Bochot, A.2
  • 13
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
    • DOI 10.1038/35888
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811. (Pubitemid 28099681)
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 14
    • 2942702257 scopus 로고    scopus 로고
    • Issues in oral nanoparticle drug carrier uptake and targeting
    • February. [Review]
    • Florence AT. (2004, February). Issues in oral nanoparticle drug carrier uptake and targeting. J Drug Target, 12(2), 65-70. [Review]
    • (2004) J Drug Target , vol.12 , Issue.2 , pp. 65-70
    • Florence, A.T.1
  • 15
    • 0036288129 scopus 로고    scopus 로고
    • Alginate/ poly-L-lysine microparticles for the intestinal delivery of antisense oligonucleotides
    • Jun
    • González Ferreiro M, Tillman LG, Hardee G, Bodmeier R. Alginate/ poly-L-lysine microparticles for the intestinal delivery of antisense oligonucleotides. Pharm Res. 2002 Jun;19(6):755-64.
    • (2002) Pharm Res , vol.19 , Issue.6 , pp. 755-764
    • González Ferreiro, M.1    Tillman, L.G.2    Hardee, G.3    Bodmeier, R.4
  • 16
    • 33646685202 scopus 로고    scopus 로고
    • Delivery strategies for siRNAmediated gene silencing
    • Apr. [Review]
    • Gilmore IR, Fox SP, Hollins AJ, Akhtar S. Delivery strategies for siRNAmediated gene silencing. Curr Drug Deliv. 2006 Apr;3(2):147-155 [Review]
    • (2006) Curr Drug Deliv , vol.3 , Issue.2 , pp. 147-155
    • Gilmore, I.R.1    Fox, S.P.2    Hollins, A.J.3    Akhtar, S.4
  • 17
    • 34248213490 scopus 로고    scopus 로고
    • Toxicogenomics of drug delivery systems: Exploiting delivery system-induced changes in target gene expression to enhance siRNA activity
    • January
    • Hollins AJ, Omidi Y, Benter IF, Akhtar S. (2007, January). Toxicogenomics of drug delivery systems: exploiting delivery system-induced changes in target gene expression to enhance siRNA activity. J Drug Target, 15(1), 83-88.
    • (2007) J Drug Target , vol.15 , Issue.1 , pp. 83-88
    • Hollins, A.J.1    Omidi, Y.2    Benter, I.F.3    Akhtar, S.4
  • 18
    • 0035282789 scopus 로고    scopus 로고
    • The cellular delivery of antisense oligonucleotides and ribozymes
    • Hughes MD, Hussain M, Nawaz Q, Sayyed P, Akhtar S. (2001). The cellular delivery of antisense oligonucleotides and ribozymes. Drug Discov Today, 6(6), 303-315.
    • (2001) Drug Discov Today , vol.6 , Issue.6 , pp. 303-315
    • Hughes, M.D.1    Hussain, M.2    Nawaz, Q.3    Sayyed, P.4    Akhtar, S.5
  • 19
    • 0035940059 scopus 로고    scopus 로고
    • Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics
    • August 23
    • Hussain N, Jaitley V, Florence AT. (2001, August 23). Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics. Adv Drug Deliv Rev, 50(1-2), 107-142.
    • (2001) Adv Drug Deliv Rev , vol.50 , Issue.1-2 , pp. 107-142
    • Hussain, N.1    Jaitley, V.2    Florence, A.T.3
  • 20
    • 22344454846 scopus 로고    scopus 로고
    • Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
    • Judge AD, Sood V, Shaw JR, Fang D, McClintock K, Maclachlan I. (2005). Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol, 23(4), 457-462.
    • (2005) Nat Biotechnol , vol.23 , Issue.4 , pp. 457-462
    • Judge, A.D.1    Sood, V.2    Shaw, J.R.3    Fang, D.4    McClintock, K.5    MacLachlan, I.6
  • 21
    • 47249138782 scopus 로고    scopus 로고
    • Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
    • July
    • Juliano R, Alam MR, Dixit V, Kang H. (2008, July). Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res, 36(12), 4158-4171.
    • (2008) Nucleic Acids Res , vol.36 , Issue.12 , pp. 4158-4171
    • Juliano, R.1    Alam, M.R.2    Dixit, V.3    Kang, H.4
  • 22
    • 33751562849 scopus 로고    scopus 로고
    • Polymer genomics: An insight into pharmacology and toxicology of nanomedicines
    • December 30
    • Kabanov AV. (2006, December 30). Polymer genomics: an insight into pharmacology and toxicology of nanomedicines. Adv Drug Deliv Rev, 58(15), 1597-1621.
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.15 , pp. 1597-1621
    • Kabanov, A.V.1
  • 23
    • 4644293047 scopus 로고    scopus 로고
    • Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: In vitro and in vivo studies
    • Khan A, Benboubetra M, Sayyed PZ, Ng KW, Fox S, Beck G, Benter IF, Akhtar S. (2004). Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies. J Drug Target, 12(6), 393-404.
    • (2004) J Drug Target , vol.12 , Issue.6 , pp. 393-404
    • Khan, A.1    Benboubetra, M.2    Sayyed, P.Z.3    Ng, K.W.4    Fox, S.5    Beck, G.6    Benter, I.F.7    Akhtar, S.8
  • 26
    • 61749088168 scopus 로고    scopus 로고
    • Innovative strategies for co-delivering antigens and CpG oligonucleotides
    • March
    • Krishnamachari Y, Salem AK. (2009, March). Innovative strategies for co-delivering antigens and CpG oligonucleotides. Adv Drug Deliv Rev, 61(3), 205-217.
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.3 , pp. 205-217
    • Krishnamachari, Y.1    Salem, A.K.2
  • 27
    • 60149094505 scopus 로고    scopus 로고
    • RNA interference: From basic research to therapeutic applications
    • Kurreck J. (2009). RNA interference: from basic research to therapeutic applications. Angew Chem Int Ed Engl, 48(8), 1378-1398.
    • (2009) Angew Chem Int Ed Engl , vol.48 , Issue.8 , pp. 1378-1398
    • Kurreck, J.1
  • 28
    • 0030467093 scopus 로고    scopus 로고
    • Gastrointestinal uptake and translocation of microparticles in the streptozotocin-diabetic rat
    • Dec
    • McMinn LH, Hodges GM, Carr KE. Gastrointestinal uptake and translocation of microparticles in the streptozotocin-diabetic rat. J Anat. 1996 Dec;189 ( Pt 3):553-559
    • (1996) J Anat , vol.189 , Issue.PART 3 , pp. 553-559
    • McMinn, L.H.1    Hodges, G.M.2    Carr, K.E.3
  • 29
    • 0347756922 scopus 로고    scopus 로고
    • Toxicogenomics of non-viral vectors for gene therapy: A microarray study of lipofectin-and oligofectamineinduced gene expression changes in human epithelial cells
    • July
    • Omidi Y, Hollins AJ, Benboubetra M, Drayton R, Benter IF, Akhtar S. (2003, July). Toxicogenomics of non-viral vectors for gene therapy: a microarray study of lipofectin- and oligofectamineinduced gene expression changes in human epithelial cells. J Drug Target, 11(6), 311-323.
    • (2003) J Drug Target , vol.11 , Issue.6 , pp. 311-323
    • Omidi, Y.1    Hollins, A.J.2    Benboubetra, M.3    Drayton, R.4    Benter, I.F.5    Akhtar, S.6
  • 30
    • 30644478022 scopus 로고    scopus 로고
    • Polypropylenimine dendrimer-induced gene expression changes: The effect of complexation with DNA, dendrimer generation and cell type
    • August
    • Omidi Y, Hollins AJ, Drayton RM, Akhtar S. (2005, August). Polypropylenimine dendrimer-induced gene expression changes: the effect of complexation with DNA, dendrimer generation and cell type. J Drug Target, 13(7), 431-443.
    • (2005) J Drug Target , vol.13 , Issue.7 , pp. 431-443
    • Omidi, Y.1    Hollins, A.J.2    Drayton, R.M.3    Akhtar, S.4
  • 31
    • 0036830625 scopus 로고    scopus 로고
    • Effect of sodium caprate on the intestinal absorption of two modified antisense oligonucleotides in pigs
    • November
    • Raoof AA, Ramtoola Z, McKenna B, Yu RZ, Hardee G, Geary RS. (2002, November). Effect of sodium caprate on the intestinal absorption of two modified antisense oligonucleotides in pigs. Eur J Pharm Sci, 17(3), 131-138.
    • (2002) Eur J Pharm Sci , vol.17 , Issue.3 , pp. 131-138
    • Raoof, A.A.1    Ramtoola, Z.2    McKenna, B.3    Yu, R.Z.4    Hardee, G.5    Geary, R.S.6
  • 32
    • 2642556483 scopus 로고    scopus 로고
    • Oral bioavailability and multiple dose tolerability of an antisense oligonucleotide tablet formulated with sodium caprate
    • June
    • Raoof AA, Chiu P, Ramtoola Z, Cumming IK, Teng C, Weinbach SP, Hardee GE, Levin AA, Geary RS. (2004, June). Oral bioavailability and multiple dose tolerability of an antisense oligonucleotide tablet formulated with sodium caprate. J Pharm Sci, 93(6), 1431-1439.
    • (2004) J Pharm Sci , vol.93 , Issue.6 , pp. 1431-1439
    • Raoof, A.A.1    Chiu, P.2    Ramtoola, Z.3    Cumming, I.K.4    Teng, C.5    Weinbach, S.P.6    Hardee, G.E.7    Levin, A.A.8    Geary, R.S.9
  • 33
    • 59849103061 scopus 로고    scopus 로고
    • Drug delivery of siRNA therapeutics: Potentials and limits of nanosystems
    • March
    • Reischl D, Zimmer A. (2009, March). Drug delivery of siRNA therapeutics: potentials and limits of nanosystems. Nanomedicine, 5(1), 8-20.
    • (2009) Nanomedicine , vol.5 , Issue.1 , pp. 8-20
    • Reischl, D.1    Zimmer, A.2
  • 35
    • 64549134275 scopus 로고    scopus 로고
    • Deciphering the code of innate immunity recognition of siRNAs
    • Sioud M. (2009). Deciphering the code of innate immunity recognition of siRNAs. Methods Mol Biol, 487, 41-59.
    • (2009) Methods Mol Biol , vol.487 , pp. 41-59
    • Sioud, M.1
  • 36
    • 38349171887 scopus 로고    scopus 로고
    • Oral delivery of antisense oligonucleotides in man
    • Tillman LG, Geary RS, Hardee GE. (2008). Oral delivery of antisense oligonucleotides in man. J Pharm Sci, 97(1), 225-236.
    • (2008) J Pharm Sci , vol.97 , Issue.1 , pp. 225-236
    • Tillman, L.G.1    Geary, R.S.2    Hardee, G.E.3
  • 37
    • 0027220386 scopus 로고
    • Penetration of oligonucleotides into mouse organism through mucosa and skin
    • Vlassov VV, Karamyshev VN, Yakubov LA. (1993). Penetration of oligonucleotides into mouse organism through mucosa and skin. FEBS Lett, 327(3), 271-274.
    • (1993) FEBS Lett , vol.327 , Issue.3 , pp. 271-274
    • Vlassov, V.V.1    Karamyshev, V.N.2    Yakubov, L.A.3
  • 38
    • 59349116903 scopus 로고    scopus 로고
    • Knocking down barriers: Advances in siRNA delivery
    • February. [Review]
    • Whitehead KA, Langer R, Anderson DG. (2009, February). Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov, 8(2), 129-138. [Review]
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.2 , pp. 129-138
    • Whitehead, K.A.1    Langer, R.2    Anderson, D.G.3
  • 39
    • 66249083866 scopus 로고    scopus 로고
    • Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
    • May 3. [Epub ahead of print]
    • Woodrow KA, Cu Y, Booth CJ, Saucier-Sawyer JK, Wood MJ, Mark Saltzman W. (2009, May 3). Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat Mater. [Epub ahead of print]
    • (2009) Nat Mater
    • Woodrow, K.A.1    Cu, Y.2    Booth, C.J.3    Saucier-Sawyer, J.K.4    Wood, M.J.5    Mark Saltzman, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.