Alcohol consumption is associated with decreased insulin resistance independent of body mass index in Japanese community-dwelling men

Tohoku Journal of Experimental Medicine

Volumn 218, Issue 4, 2009, Pages 331-337

  Kawamoto, Ryuichi ^a,b   Kohara, Katsuhiko ^a   Tabara, Yasuharu ^a   Miki, Tetsuro ^a   Ohtsuka, Nobuyuki ^b   Kusunoki, Tomo ^a,b   Abe, Masanori ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Seiyo Municipal Nomura Hospital   (Japan)

Author keywords

Alcohol consumption; Body mass index; Insulin resistance; Men; Risk factor

Indexed keywords

ADIPONECTIN; ALCOHOL; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; URIC ACID;

ADULT; AGE; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; BODY WEIGHT; CIGARETTE SMOKING; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRINKING BEHAVIOR; DYSLIPIDEMIA; HUMAN; HYPERTENSION; INSULIN RESISTANCE; JAPANESE; MAJOR CLINICAL STUDY; MALE; MEDICAL EXAMINATION; OBESITY; QUESTIONNAIRE; STRUCTURED INTERVIEW; SYSTOLIC BLOOD PRESSURE; AGED; ETHNOLOGY; JAPAN; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; REGRESSION ANALYSIS; RISK FACTOR; SMOKING;

ADULT; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; BODY MASS INDEX; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN RESISTANCE; JAPAN; MALE; MIDDLE AGED; REGRESSION ANALYSIS; RISK FACTORS; SMOKING;

EID: 70349763971     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.218.331     Document Type: Article

References (35)

1. Adelman, R.D. (2002) Obesity and renal disease. Curr. Opin. Nephrol. Hypertens., 11, 331-335.
2. Ajani, U.A., Hennekens, C.H., Speisberg, A. & Manson, J.E. (2000) Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians. Arch. Intern. Med., 160, 1025-1030.
3. Bell, R.A., Mayer-Davis, E.J., Martin, M.A., D'Agostino, R.B. Jr. & Haffner, S.M. (2000) Associations between alcohol consumption and insulin sensitivity and cardiovascular disease risk factors: the Insulin Resistance and Atherosclerosis Study. Diabetes Care, 23, 1630-1636.
4. Beulens, J.W., de Zoete, E.C., Kok, F.J., Schaafsma, G. & Hendriks, H.F. (2007) Effect of moderate alcohol consumption on adipokines and insulin sensitivity in lean and overweight men: a diet intervention study. Eur. J. Clin. Nutr., 62, 1098-1105.
5. Chang, S.A., Kim, H.S., Yoon, K.H., Ko, S.H., Kwon, H.S., Kim, S.R., Lee, W.C., Yoo, S.J., Son, H.S., Cha, B.Y., Lee, K.W., Son, H.Y. & Kang, S.K. (2004) Body mass index is the most important determining factor for the degree of insulin resistance in non-obese type 2 diabetic patients in Korea. Metabolism, 53, 142-146.
6. Cnop, M., Havel, R.J., Utzschneider, K.M., Carr, D.B., Sinha, M.K., Boyko, E.J., Retzlaff, B.M., Knopp, R.H., Brunzell, J.D. & Kahn S.E. (2003) Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia, 46, 459-469. (Pubitemid 36577787)
7. Conigrave, K.M., Hu, B.F., Camargo, C.A., Stampfer, M.J., Willet, W.C. & Rimm, E.B. (2001) A prospective study of drinking patterns in relation to risk of type 2 diabetes among men. Diabetes, 50, 2390-2395. (Pubitemid 33641927)
8. De Vegt, F., Dekker, J.M., Groeneveld, W.J., Nijpels, C., Stehouwer, C.D., Bouter, L.M. & Heine, R.J. (2002) Moderate alcohol consumption is associated with lower risk for incident diabetes and mortality: the Hoorn Study. Diabetes Res. Clin. Pract., 57, 53-60.
9. Esteghamati, A., Khalilzadeh, O., Anvari, M., Ahadi, M.S., Abbasi, M. & Rashidi, A. (2008) Metabolic syndrome and insulin resistance significantly correlate with body mass index. Arch. Med. Res., 39, 803-808.
10. Flanagan, D.E.H., Moore, V.M., Godsland, I.F., Cockington, R.A., Robinson, J.S. & Phillips, D.I. (2000) Alcohol consumption and insulin resistance in young adults. Eur. J. Clin. Invest., 30, 297-301.
11. Friedewald, W.T., Levy, R.I. & Fredrickson, D.S. (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem., 18, 499-502.
12. Goude, D., Fagerberg, B. & Hulthe, J. (2002) Alcohol consumption, the metabolic syndrome and insulin resistance in 58-year-old clinically healthy men (AIR study). Clin. Sci., 102, 345-352. (Pubitemid 34214398)
13. Hong, J., Smith, R.R., Harvey, A.E. & Núñez, N.P. (2009) Alcohol consumption promotes insulin sensitivity without affecting body fat levels. Int. J. Obes. (Lond), 33, 197-203.
14. Kambham, N., Markowitz, C.S., Valeri, A.M., Lin, J. & D'Agati, V.D. (2001) Obesity-related glomerulopathy: an emerging epidemic. Kidney Int., 59, 1498-1509. (Pubitemid 32281241)
15. Kawamoto, R., Ohtsuka, N., Ninomiya, D. & Nakamura, S. (2007) Carotid Atherosclerosis in Normal-Weight Metabolic Syndrome. Internal Medicine, 46, 1771-1777, (Pubitemid 350131028)
16. Khaodhiar, L., Linq, P.R., Blackburn, C.L. & Bristrian, B.R. (2004) Serum levels of interleukin-6 and c-reactive protein correlate with body mass index across the broad range of obesity. J. Parenter. Enteral. Nutr., 28, 410-415.
17. Kiechl, S., Willeit, J., Poewe, W., Egger, C., Oberhollenzer, F., Muggeo, M. & Bonora, E. (1996) Insulin sensitivity and regular alcohol consumption: large, prospective, cross sectional population study (Bruneck study). BMJ, 313, 1040-1044. (Pubitemid 26371868)
18. Kishimoto, N., Okita, K., Takada, S., Sakuma, I., Saijo, Y., Chiba, H., Ishii, K., Kishi, R. & Tsutsui, H. (2009) Lipoprotein metabolism, insulin resistance, and adipocytokine levels in Japanese female adolescents with a normal body mass index and high body fat mass. Circ J., 73, 534-539.
19. Knight, S.F. & Imig, J.D. (2007) Obesity, insulin resistance, and renal function. Microcirculation, 14, 349-362. (Pubitemid 47050027)
20. Krzystek-Korpacka, M., Patryn, E., Boehm, D., Berdowska, I., Zielinski, B. & Noczynska, A. (2008) Advanced oxidation protein products (AOPPs) in juvenile overweight and obesity prior to and following weight reduction. Clin. Biochem., 41, 943-949.
21. Lazarus, R., Sparrow, D. & Weiss, S.T. (1997) Alcohol intake and insulin levels: the Normative Aging Study. Am. J. Epidemiol., 145, 909-916.
22. Masuo, K., Mikami, H., Itoh, M., Ogihara, T. & Tuck, M.L. (2000) Sympathetic activity and body mass index contribute to blood pressure levels. Hypertens. Res., 23, 303-310.
23. Mathew, B., Patel, S.B., Reams, C.R., Freeman, R.H., Spear, R.M. & Villarreal, D. (2007) Obesity-hypertension: emerging concepts in pathophysiology and treatment. Am. J. Med. Sci., 334, 23-30.
24. Matthews, D.R., Hosker, J.P., Rudenski, A.S., Naylor, B.A., Treacher, D.F. & Turner, R.C. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412-419. (Pubitemid 15018832)
25. Mayer, E.J., Newman, B., Quesenberry, C.P. Jr., Friedman, C.D. & Selby, J.V. (1993) Alcohol consumption and insulin concentrations. Role of insulin in associations of alcohol intake with high-density lipoprotein cholesterol and triglycerides. Circulation, 88, 2190-2197.
26. Ouchi, N., Kihara, S., Arita, Y., Maeda, K., Kuriyama, H., Okamoto, Y., Hotta, K., Nishida, M., Takahashi, M., Nakamura, T., Yamashita, S., Funahashi, T. & Matsuzawa, Y. (1999) Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation, 100, 2473-2476. (Pubitemid 30005109)
27. Rossi, C.P., Belfiore, A., Bernini, C., Fabris, B., Caridi, C., Ferri, C., Giacchetti, C., Letizia, C., Maccario, M., Mannelli, M., Palumbo, C., Patalano, A., Rizzoni, D., Rossi, E., Pessina, A.C. & Mantero, F. (2008) Primary Aldosteronism Prevalence in hypertension Study Investigators: Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients. J. Clin. Endocrinol. Metab., 93, 2566-2571.
28. Rutkowski, P., Klassen, A., Sebekova, K., Bahner, U. & Heidland, A. (2006) Renal disease in obesity: the need for greater attention. J. Ren. Nutr., 16, 216-223.
29. Sierksma, A., Patel, H., Ouchi, N., Kihara, S., Funahashi, T., Heine, R.J., Grobbee, D.E., Kluft, C. & Hendriks, H.F. (2004) Effect of moderate alcohol consumption on adiponectin, tumor necrosis factor-alpha, and insulin sensitivity. Diabetes Care, 27, 184-189. (Pubitemid 38196730)
30. Suter, P.M., Schutz, Y. & Jequier, E. (1992) The effect of ethanol on fat storage in healthy subjects. N. Engl. J. Med., 326, 983-987.
31. Thamer, C., Haap, M., Fritsche, A., Haering, H. & Stumvoll, M. (2004) Relationship between moderate alcohol consumption and adiponectin and insulin sensitivity in a large heterogeneous population. Diabetes Care, 27, 1240-1240 (Pubitemid 38579807)
32. Villegas, R., Salim, A., O'Halloran, D. & Perry, I.J. (2004) Alcohol intake and insulin resistance. A cross-sectional study. Nutr. Metab. Cardiovasc. Dis., 14, 233-240.
33. Visser, M., Bouter, L.M., McQuillan, C.M., Wener, M.H. & Harris, T.B. (1999) Elevated C-reactive protein levels in overweight and obese adults. JAMA, 282, 2131-2135.
34. Wei, M., Gibbons, L.W., Mitchell, T.L., Kampert, J.B. & Blair, S.N. (2000) Alcohol intake and incidence of type 2 diabetes in men. Diabetes Care, 23, 18-22. (Pubitemid 30022888)
35. Yamada, Y., Noborisaka, Y., Ishizaki, M., Tsurutani, I., Honda, R. & Yamada, S. (2004) Alcohol consumption, homeostasis model assessment indices and blood pressure in middle-aged healthy men. J. Hum. Hypertens., 18, 343-350.