Tetralogy of Fallot as a Model to Study Cardiac Progenitor Cell Migration and Differentiation During Heart Development

Trends in Cardiovascular Medicine

Volumn 19, Issue 4, 2009, Pages 130-135

  Di Felice, Valentina ^a   Zummo, Giovanni ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR LHX9; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN MULTITYPE 2;

CARDIAC STEM CELL; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL RENEWAL; CHROMOSOME 22Q; CHROMOSOME DELETION; EMBRYO DEVELOPMENT; FALLOT TETRALOGY; GENE MUTATION; GENETIC ASSOCIATION; HEART DEVELOPMENT; HEART HEMODYNAMICS; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE TACHYCARDIA; HETEROZYGOSITY; HUMAN; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; REVIEW; STEM CELL; TRISOMY 21;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL MOVEMENT; CELL PROLIFERATION; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; MUTATION; MYOCARDIUM; ORGANOGENESIS; STEM CELLS; TETRALOGY OF FALLOT; TRANSCRIPTION FACTORS;

EID: 70349762818     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcm.2009.07.004     Document Type: Review

References (39)

1. Akazawa H., and Komuro I. Cardiac transcription factor Csx/Nkx2-5: its role in cardiac development and diseases. Pharmacol Ther 107 (2005) 252-268
2. Akcaboy M.I., Cengiz F.B., Inceoglu B., et al. The effect of p.Arg25Cys alteration in NKX2-5 on conotruncal heart anomalies: mutation or polymorphism. Pediatr Cardiol 29 (2008) 126-129
3. Artavanis-Tsakonas S., Rand M.D., and Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 284 (1999) 770-776
4. Beltrami A.P., Barlucchi L., Torella D., et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114 (2003) 763-776
5. Biben C., Weber R., Kesteven S., et al. Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5. Circ Res 87 (2000) 888-895
6. Boon A.R., Farmer M.B., and Roberts D.F. A family study of Fallot's tetralogy. J Med Genet 9 (1972) 179-192
7. Cai C.L., Liang X., Shi Y., et al. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 5 (2003) 877-889
8. Cohen E.D., Wang Z., Lepore J.J., et al. Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J Clin Invest 117 (2007) 1794-1804
9. Crispino J.D., Lodish M.B., Thurberg B.L., et al. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev 15 (2001) 839-844
10. De la Cruz M.V., Sanchez Gomez C., Arteaga M.M., and Arguello C. Experimental study of the development of the truncus and the conus in the chick embryo. J Anat 123 (1977) 661-686
11. Di Felice V., De Luca A., Colorito M.L., et al. Cardiac stem cell research: an elephant in the room. Anat Rec 292 (2009) 449-454
12. Eldadah Z.A., Hamosh A., Biery N.J., et al. Familial tetralogy of Fallot caused by mutation in the jagged1 gene. Hum Mol Genet 10 (2001) 163-169
13. Gioli-Pereira L., Pereira A.C., Mesquita S.M., et al. NKX2.5 mutations in patients with non-syndromic congenital heart disease. Int J Cardiol (2008) 2008 Dec 14. [Epub ahead of print]
14. Goldmuntz E., Geiger E., and Benson D.W. NKX2.5 mutations in patients with tetralogy of Fallot. Circulation 104 (2001) 2565-2568
15. Harrison D.A., Harris L., Siu S.C., et al. Sustained ventricular tachycardia in adult patients late after repair of tetralogy of Fallot. J Am Coll Cardiol 30 (1997) 1368-1373
16. Ho S., McCarthy K.P., Josen M., and Rigby M.L. Anatomic-echocardiographic correlates: an introduction to normal and congenitally malformed hearts. Heart 86 Suppl 2 (2001) II3-II11
17. Karamlou T., McCrindle B.W., and Williams W.G. Surgery insight: late complications following repair of tetralogy of Fallot and related surgical strategies for management. Nat Clin Pract Cardiovasc Med 3 (2006) 611-622
18. Kelly R.G., Brown N.A., and Buckingham M.E. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev Cell 1 (2001) 435-440
19. Laugwitz K.L., Moretti A., Lam J., et al. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 433 (2005) 647-653
20. Lyons I., Parsons L.M., Hartley L., et al. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev 9 (1995) 1654-1666
21. Ma Q., Zhou B., and Pu W.T. Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity. Dev Biol 323 (2008) 98-104
22. McElhinney D.B., Geiger E., Blinder J., et al. NKX2.5 mutations in patients with congenital heart disease. J Am Coll Cardiol 42 (2003) 1650-1655
23. Nemer G., Fadlalah F., Usta J., et al. A novel mutation in the GATA4 gene in patients with Tetralogy of Fallot. Hum Mutat 27 (2006) 293-294
24. Okubo A., Miyoshi O., Baba K., et al. A novel GATA4 mutation completely segregated with atrial septal defect in a large Japanese family. J Med Genet 41 (2004) e97
25. Paladini D., Pacileo G., Palmieri S., et al. Prenatal diagnosis of 22q11 microdeletion in a fetus with a conotruncal heart defect. Ultrasound Obstet Gynecol 11 (1998) 68-70
26. Peterkin T., Gibson A., Loose M., and Patient R. The roles of GATA-4, -5 and -6 in vertebrate heart development. Semin Cell Dev Biol 16 (2005) 83-94
27. Pizzuti A., Sarkozy A., Newton A.L., et al. Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Hum Mutat 22 (2003) 372-377
28. Qyang Y., Martin-Puig S., Chiravuri M., et al. The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell 1 (2007) 165-179
29. Restivo A., Piacentini G., Placidi S., et al. Cardiac outflow tract: a review of some embryogenetic aspects of the conotruncal region of the heart. Anat Rec A Discov Mol Cell Evol Biol 288 (2006) 936-943
30. Saliba Z., Le Bidois J., Sidi D., et al. Prenatal detection of a tetralogy of Fallot with origin of the left pulmonary artery from the ascending aorta in a familial 22q11 microdeletion. Prenat Diagn 19 (1999) 260-262
31. Smagulova F.O., Manuylov N.L., Leach L.L., and Tevosian S.G. GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development. BMC Dev Biol 8 67 (2008)
32. Snarr B.S., O'Neal J.L., Chintalapudi M.R., et al. Isl1 expression at the venous pole identifies a novel role for the second heart field in cardiac development. Circ Res 101 (2007) 971-974
33. Spinner N.B., Colliton R.P., Crosnier C., et al. Jagged1 mutations in Alagille syndrome. Hum Mutat 17 (2001) 18-33
34. Svensson E.C., Huggins G.S., Lin H., et al. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nat Genet 25 (2000) 353-356
35. Tanaka M., Chen Z., Bartunkova S., et al. The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development 126 (1999) 1269-1280
36. Tevosian S.G., Deconinck A.E., Tanaka M., et al. FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. Cell 101 (2000) 729-739
37. Waldo K.L., Kumiski D.H., Wallis K.T., et al. Conotruncal myocardium arises from a secondary heart field. Development 128 (2001) 3179-3188
38. Ward C., Stadt H., Hutson M., and Kirby M.L. Ablation of the secondary heart field leads to tetralogy of Fallot and pulmonary atresia. Dev Biol 284 (2005) 72-83
39. Zhou B., von Gise A., Ma Q., et al. Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium. Biochem Biophys Res Commun 375 (2008) 450-453