Synthesis and characterization of the Zn(II) and Cu(II) piperidinyl isoeuxanthone complexes: DNA-binding and cytotoxic activity

European Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2009, Pages 4509-4515

  Wang, Hui Fang ^a   Shen, Rui ^b   Tang, Ning ^a  

^a LANZHOU UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

1 Hydroxy 6 (2 (1 piperidinyl)ethoxy)xanthone; Cu(II) complex; Cytotoxic activity; DNA binding; Intercalative mode; Zn(II) complex

Indexed keywords

1 HYDROXY 6 [2 (1 PIPERIDINYL)ETHOXY]XANTHONE; COPPER COMPLEX; CUPRIC ION; ETHIDIUM BROMIDE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE; ZINC COMPLEX; ZINC ION;

ABSORPTION SPECTROSCOPY; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ESOPHAGUS CANCER; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; LUNG ADENOCARCINOMA; PROTON NUCLEAR MAGNETIC RESONANCE; SQUAMOUS CELL CARCINOMA; STOMACH CANCER; ULTRAVIOLET SPECTROSCOPY;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CATTLE; CELL LINE, TUMOR; CELL SURVIVAL; COPPER; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; ESOPHAGEAL NEOPLASMS; HUMANS; LUNG NEOPLASMS; NEOPLASMS; SPECTROSCOPY, NEAR-INFRARED; STOMACH NEOPLASMS; VISCOSITY; XANTHONES; ZINC;

EID: 70349762509     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.06.019     Document Type: Article

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