-
1
-
-
0037389094
-
SCCM/ESICM/ACCP/ATS/SIS International sepsis definitions conference
-
Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G: 2001 SCCM/ESICM/ACCP/ATS/SIS International sepsis definitions conference. Crit Care Med 31:1250-1256, 2003.
-
(2001)
Crit Care Med
, vol.31
, pp. 1250-1256
-
-
Levy, M.M.1
Fink, M.P.2
Marshall, J.C.3
Abraham, E.4
Angus, D.5
Cook, D.6
Cohen, J.7
Opal, S.M.8
Vincent, J.L.9
Ramsay, G.10
-
2
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin GS, Mannino DM, Eaton S, Moss M: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348:1546-1554, 2003.
-
(2003)
N Engl J Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
3
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR: Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29:1303-1310, 2001.
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
4
-
-
0038482456
-
Such stuff as dreams are made on: Mediator-directed therapy in sepsis
-
Marshall JC: Such stuff as dreams are made on: mediator-directed therapy in sepsis. Nat Rev Drug Discov 2:391-405, 2003.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 391-405
-
-
Marshall, J.C.1
-
6
-
-
13244288781
-
The "cytokine profile": A code for sepsis
-
Ulloa L, Tracey KJ: The "cytokine profile": a code for sepsis. Trends Mol Med 11:56-63, 2005.
-
(2005)
Trends Mol Med
, vol.11
, pp. 56-63
-
-
Ulloa, L.1
Tracey, K.J.2
-
7
-
-
4744359153
-
Genetic determinants of the inflammatory response
-
Imahara SD, O'Keefe GE: Genetic determinants of the inflammatory response. Curr Opin Crit Care 10:318-324, 2004.
-
(2004)
Curr Opin Crit Care
, vol.10
, pp. 318-324
-
-
Imahara, S.D.1
O'Keefe, G.E.2
-
8
-
-
0037904920
-
Measures, markers, and mediators: Toward a staging system for clinical sepsis
-
A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26 2000
-
Marshall JC, Vincent JL, Fink MP, Cook DJ, Rubenfeld G, Foster D, Fisher CJ Jr, Faist E, Reinhart K: Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000. Crit Care Med 31:1560-1567, 2003.
-
(2003)
Crit Care Med
, vol.31
, pp. 1560-1567
-
-
Marshall, J.C.1
Vincent, J.L.2
Fink, M.P.3
Cook, D.J.4
Rubenfeld, G.5
Foster, D.6
Jr F.Cj7
Faist, E.8
Reinhart, K.9
-
10
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
Hotchkiss RS, Nicholson DW: Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 6:813-822, 2006.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
11
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
Hotchkiss RS, Swanson PE, Freeman BD, Tinsley KW, Cobb JP, Matuschak GM, Buchman TG, Karl IE: Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 27:1230-1251, 1999.
-
(1999)
Crit Care Med
, vol.27
, pp. 1230-1251
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
12
-
-
23044477087
-
Leukocyte apoptosis and its significance in sepsis and shock
-
Wesche DE, Lomas-Neira JL, Perl M, Chung CS, Ayala A: Leukocyte apoptosis and its significance in sepsis and shock. J Leukoc Biol 78:325-337, 2005.
-
(2005)
J Leukoc Biol
, vol.78
, pp. 325-337
-
-
Wesche, D.E.1
Lomas-Neira, J.L.2
Perl, M.3
Chung, C.S.4
Ayala, A.5
-
13
-
-
0032734726
-
Clinical aspects: From systemic inflammation to 'immunoparalysis'
-
Volk HD, Reinke P, Döcke WD: Clinical aspects: from systemic inflammation to 'immunoparalysis'. Chem Immunol 74:162-177, 2000.
-
(2000)
Chem Immunol
, vol.74
, pp. 162-177
-
-
Volk, H.D.1
Reinke, P.2
Döcke, W.D.3
-
14
-
-
0029903114
-
Sir Isaac Newton, sepsis, SIRS, and CARS
-
Bone RC: Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med 24: 1125-1128, 1996.
-
(1996)
Crit Care Med
, vol.24
, pp. 1125-1128
-
-
Bone, R.C.1
-
15
-
-
5644241698
-
Dysregulation of the immune response in severe sepsis
-
Pinsky MR: Dysregulation of the immune response in severe sepsis. Am J Med Sci 328:220-229, 2004.
-
(2004)
Am J Med Sci
, vol.328
, pp. 220-229
-
-
Pinsky, M.R.1
-
16
-
-
0035434019
-
Sepsis syndromes: Understanding the role of innate and acquired immunity
-
Oberholzer A, Oberholzer C, Moldawer LL: Sepsis syndromes: understanding the role of innate and acquired immunity. Shock 16:83-96, 2001.
-
(2001)
Shock
, vol.16
, pp. 83-96
-
-
Oberholzer, A.1
Oberholzer, C.2
Moldawer, L.L.3
-
17
-
-
0034641931
-
Corpse clearance defines the meaning of cell death
-
Savill J, Fadok V: Corpse clearance defines the meaning of cell death. Nature 407:784-788, 2000.
-
(2000)
Nature
, vol.407
, pp. 784-788
-
-
Savill, J.1
Fadok, V.2
-
18
-
-
1542511202
-
Death-defying immunity: Do apoptotic cells influence antigen processing and presentation?
-
Albert ML: Death-defying immunity: do apoptotic cells influence antigen processing and presentation? Nat Rev Immunol 4:223-231, 2004.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 223-231
-
-
Albert, M.L.1
-
19
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans
-
Hotchkiss RS, Tinsley KW, Swanson PE, et al.: Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol 166:6952-6963, 2001.
-
(2001)
J Immunol
, vol.166
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
-
20
-
-
0036499162
-
Depletion of dendritic cells, but not macrophages, in patients with sepsis
-
Hotchkiss RS, Tinsley KW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP, Coopersmith C, Karl IE: Depletion of dendritic cells, but not macrophages, in patients with sepsis. J Immunol 168:2493-2500, 2002.
-
(2002)
J Immunol
, vol.168
, pp. 2493-2500
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Grayson, M.H.4
Osborne, D.F.5
Wagner, T.H.6
Cobb, J.P.7
Coopersmith, C.8
Karl, I.E.9
-
21
-
-
14844343217
-
Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure
-
Felmet KA, Hall MW, Clark RS, Jaffe R, Carcillo JA: Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure. J Immunol 174:3765-3772, 2005.
-
(2005)
J Immunol
, vol.174
, pp. 3765-3772
-
-
Felmet, K.A.1
Hall, M.W.2
Clark, R.S.3
Jaffe, R.4
Carcillo, J.A.5
-
22
-
-
85047692486
-
Spleen depletion in neonatal sepsis and chorioamnionitis
-
Toti P, De FC, Occhini R, Schuerfeld K, Stumpo M, Epistolato MC, Vatti R, Buonocore G: Spleen depletion in neonatal sepsis and chorioamnionitis. Am J Clin Pathol 122:765-771, 2004.
-
(2004)
Am J Clin Pathol
, vol.122
, pp. 765-771
-
-
Toti, P.1
De Fc Occhini, R.2
Schuerfeld, K.3
Stumpo, M.4
Epistolato, M.C.5
Vatti, R.6
Buonocore, G.7
-
23
-
-
33745617094
-
Neutrophils in development of multiple organ failure in sepsis
-
Brown KA, Brain SD, Pearson JD, Edgeworth JD, Lewis SM, Treacher DF: Neutrophils in development of multiple organ failure in sepsis. Lancet 368:157-169, 2006.
-
(2006)
Lancet
, vol.368
, pp. 157-169
-
-
Brown, K.A.1
Brain, S.D.2
Pearson, J.D.3
Edgeworth, J.D.4
Lewis, S.M.5
Treacher, D.F.6
-
24
-
-
28944454528
-
Neutrophils in the pathogenesis of sepsis
-
Marshall JC: Neutrophils in the pathogenesis of sepsis. Crit Care Med 33:S502YS505, 2005.
-
(2005)
Crit Care Med
, vol.33
-
-
Marshall, J.C.1
-
25
-
-
21644476233
-
Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment
-
von Gunten S, Yousefi S, Seitz M, Jakob SM, Schaffner T, Seger R, Takala J, Villiger PM, Simon HU: Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment. Blood 106:1423-1431, 2005.
-
(2005)
Blood
, vol.106
, pp. 1423-1431
-
-
Von Gunten, S.1
Yousefi, S.2
Seitz, M.3
Jakob, S.M.4
Schaffner, T.5
Seger, R.6
Takala, J.7
Villiger, P.M.8
Simon, H.U.9
-
26
-
-
3142704153
-
Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity
-
Taneja R, Parodo J, Jia SH, Kapus A, Rotstein OD, Marshall JC: Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity. Crit Care Med 32:1460-1469, 2004.
-
(2004)
Crit Care Med
, vol.32
, pp. 1460-1469
-
-
Taneja, R.1
Parodo, J.2
Jia, S.H.3
Kapus, A.4
Rotstein, O.D.5
Marshall, J.C.6
-
27
-
-
0037394676
-
Neutrophils and acute lung injury
-
Abraham E: Neutrophils and acute lung injury. Crit Care Med 31:S195YS199, 2003.
-
(2003)
Crit Care Med
, vol.31
-
-
Abraham, E.1
-
28
-
-
0038171416
-
Neutrophil apoptosis pathways and their modifications in inflammation
-
Simon HU: Neutrophil apoptosis pathways and their modifications in inflammation. Immunol Rev 193:101-110, 2003.
-
(2003)
Immunol Rev
, vol.193
, pp. 101-110
-
-
Simon, H.U.1
-
30
-
-
33646230779
-
Sialic acid binding immunoglobulinYlike lectins may regulate innate immune responses by modulating the life span of granulocytes
-
von Gunten S, Simon HU: Sialic acid binding immunoglobulinYlike lectins may regulate innate immune responses by modulating the life span of granulocytes. FASEB J 20:601-605, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 601-605
-
-
Von Gunten, S.1
Simon, H.U.2
-
31
-
-
29444437433
-
SiglecsVthe major subfamily of I-type lectins
-
Varki A, Angata T: SiglecsVthe major subfamily of I-type lectins. Glycobiology 16:1RY27R, 2006.
-
(2006)
Glycobiology
, vol.16
-
-
Varki, A.1
Angata, T.2
-
32
-
-
33845483093
-
Immunologic and functional evidence for antiYSiglec-9 autoantibodies in intravenous immunoglobulin preparations
-
von Gunten S, Schaub A, Vogel M, Stadler BM, Miescher S, Simon HU: Immunologic and functional evidence for antiYSiglec-9 autoantibodies in intravenous immunoglobulin preparations. Blood 108:4255-4259, 2006.
-
(2006)
Blood
, vol.108
, pp. 4255-4259
-
-
Von Gunten, S.1
Schaub, A.2
Vogel, M.3
Stadler, B.M.4
Miescher, S.5
Simon, H.U.6
-
33
-
-
0026874127
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20:864-874, 1992.
-
(1992)
Crit Care Med
, vol.20
, pp. 864-874
-
-
-
34
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, Brunner T, Simon HU: Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 8:1124-1132, 2006.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
Ziemiecki, A.4
Schaffner, T.5
Scapozza, L.6
Brunner, T.7
Simon, H.U.8
-
35
-
-
0036155137
-
Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils
-
Daigle I, Yousefi S, Colonna M, Green DR, Simon HU: Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils. Nat Med 8:61-67, 2002.
-
(2002)
Nat Med
, vol.8
, pp. 61-67
-
-
Daigle, I.1
Yousefi, S.2
Colonna, M.3
Green, D.R.4
Simon, H.U.5
-
36
-
-
0242657656
-
The interleukin- 13 production by peripheral blood T cells from atopic dermatitis patients does not require CD2 costimulation
-
Simon D, von Gunten S, Borelli S, Braathen LR, Simon HU: The interleukin- 13 production by peripheral blood T cells from atopic dermatitis patients does not require CD2 costimulation. Int Arch Allergy Immunol 132:148-155, 2003.
-
(2003)
Int Arch Allergy Immunol
, vol.132
, pp. 148-155
-
-
Simon, D.1
Von Gunten, S.2
Borelli, S.3
Braathen, L.R.4
Simon, H.U.5
-
37
-
-
2542466891
-
Inflammation-associated cellcycleYindependent block of apoptosis by survivin in terminally differentiated neutrophils
-
Altznauer F, Martinelli S, Yousefi S, et al.: Inflammation-associated cellcycleYindependent block of apoptosis by survivin in terminally differentiated neutrophils. J Exp Med 199:1343-1354, 2004.
-
(2004)
J Exp Med
, vol.199
, pp. 1343-1354
-
-
Altznauer, F.1
Martinelli, S.2
Yousefi, S.3
-
38
-
-
0035208625
-
Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis
-
Daigle I, Simon HU: Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis. Int Arch Allergy Immunol 126:147-156, 2001.
-
(2001)
Int Arch Allergy Immunol
, vol.126
, pp. 147-156
-
-
Daigle, I.1
Simon, H.U.2
-
39
-
-
33947499837
-
SOCS3 targets Siglec 7 for proteosomal degradation and blocks Siglec 7-mediated responses
-
Orr SJ, Morgan NM, Buick RJ, Boyd CR, Elliott J, Burrows JF, Jefferies CA, Crocker PR, Johnston JA: SOCS3 targets Siglec 7 for proteosomal degradation and blocks Siglec 7-mediated responses. J Biol Chem 282:3418-3422, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 3418-3422
-
-
Orr, S.J.1
Morgan, N.M.2
Buick, R.J.3
Boyd, C.R.4
Elliott, J.5
Burrows, J.F.6
Jefferies, C.A.7
Crocker, P.R.8
Johnston, J.A.9
-
40
-
-
33846864687
-
CD33 responses are blocked by SOCS3 through accelerated proteasomalmediated turnover
-
Orr SJ, Morgan NM, Elliott J, Burrows JF, Scott CJ, McVicar DW, Johnston JA: CD33 responses are blocked by SOCS3 through accelerated proteasomalmediated turnover. Blood 109:1061-1068, 2007.
-
(2007)
Blood
, vol.109
, pp. 1061-1068
-
-
Orr, S.J.1
Morgan, N.M.2
Elliott, J.3
Burrows, J.F.4
Scott, C.J.5
McVicar, D.W.6
Johnston, J.A.7
-
41
-
-
0035829842
-
Early goaldirected therapy in the treatment of severe sepsis and septic shock
-
Early Goal-Directed Therapy Collaborative Group
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group: Early goaldirected therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368-1377, 2001.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
-
42
-
-
27544464728
-
Early and innovative interventions for severe sepsis and septic shock: Taking advantage of a window of opportunity
-
Rivers EP, McIntyre L, Morro DC, Rivers KK: Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunity. CMAJ 173:1054-1065, 2005.
-
(2005)
CMAJ
, vol.173
, pp. 1054-1065
-
-
Rivers, E.P.1
McIntyre, L.2
Morro, D.C.3
Rivers, K.K.4
-
43
-
-
33646230779
-
Sialic acid binding immunoglobulinYlike lectins may regulate innate immune responses by modulating the life span of granulocytes
-
von Gunten S, Simon HU: Sialic acid binding immunoglobulinYlike lectins may regulate innate immune responses by modulating the life span of granulocytes. FASEB J 20:601-605, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 601-605
-
-
Von Gunten, S.1
Simon, H.U.2
-
44
-
-
51749118051
-
Natural anti-Siglec autoantibodies mediate potential immunoregulatory mechanisms: Implications for the clinical use of intravenous immunoglobulins (IVIg)
-
von Gunten S, Simon HU: Natural anti-Siglec autoantibodies mediate potential immunoregulatory mechanisms: implications for the clinical use of intravenous immunoglobulins (IVIg). Autoimmun Rev 7:453-456, 2008.
-
(2008)
Autoimmun Rev
, vol.7
, pp. 453-456
-
-
Von Gunten, S.1
Simon, H.U.2
-
45
-
-
56549099820
-
Basic and clinical immunology of Siglecs
-
von Gunten S, Bochner BS: Basic and clinical immunology of Siglecs. Ann N Y Acad Sci 1143:61-82, 2008.
-
(2008)
Ann N y Acad Sci
, vol.1143
, pp. 61-82
-
-
Von Gunten, S.1
Bochner, B.S.2
-
46
-
-
33847276096
-
Appropriate use of intravenous immunoglobulin in neonatal neutropenia
-
Buenz EJ, Howe CL: Appropriate use of intravenous immunoglobulin in neonatal neutropenia. J Perinatol 27:196-197, 2007.
-
(2007)
J Perinatol
, vol.27
, pp. 196-197
-
-
Buenz, E.J.1
Howe, C.L.2
-
47
-
-
34047161745
-
Intravenous immunoglobulin preparations contain antiYSiglec-8 autoantibodies
-
von Gunten S, Vogel M, Schaub A, Stadler BM, Miescher S, Crocker PR, Simon HU: Intravenous immunoglobulin preparations contain antiYSiglec-8 autoantibodies. J Allergy Clin Immunol 119:1005-1011, 2007.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1005-1011
-
-
Von Gunten, S.1
Vogel, M.2
Schaub, A.3
Stadler, B.M.4
Miescher, S.5
Crocker, P.R.6
Simon, H.U.7
-
48
-
-
25144477056
-
Mechanism of Siglec-8Yinduced human eosinophil apoptosis: Role of caspases and mitochondrial injury
-
Nutku E, Hudson SA, Bochner BS: Mechanism of Siglec-8Yinduced human eosinophil apoptosis: role of caspases and mitochondrial injury. Biochem Biophys Res Commun 336:918-924, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 918-924
-
-
Nutku, E.1
Hudson, S.A.2
Bochner, B.S.3
-
49
-
-
0038730955
-
The inhibitory effect of anti-CD33 monoclonal antibodies on AML cell growth correlates with Syk and/or ZAP-70 expression
-
Balaian L, Zhong R, Ball ED: The inhibitory effect of anti-CD33 monoclonal antibodies on AML cell growth correlates with Syk and/or ZAP-70 expression. Exp Hematol 31:363-371, 2003.
-
(2003)
Exp Hematol
, vol.31
, pp. 363-371
-
-
Balaian, L.1
Zhong, R.2
Ball, E.D.3
|