Mechanism of Siglec-8-induced human eosinophil apoptosis: Role of caspases and mitochondrial injury

Biochemical and Biophysical Research Communications

Volumn 336, Issue 3, 2005, Pages 918-924

  Nutku, Esra ^a   Hudson, Sherry A ^a   Bochner, Bruce S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspases; Human eosinophils; Mitochondria; Siglec 8; TMRE staining

Indexed keywords

ANTIBODY; CASPASE; CASPASE 3; CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE INHIBITOR; CITRININ; GLYCOPROTEIN; REACTIVE OXYGEN METABOLITE; ROTENONE; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN 8; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY REACTION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; EOSINOPHIL; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; APOPTOSIS; CASPASE 8; CASPASE 9; CASPASES; ELECTRON TRANSPORT; EOSINOPHILS; HUMANS; LECTINS; MEMBRANE POTENTIALS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 25144477056     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.202     Document Type: Article

References (37)

1. K.K. Kikly, B.S. Bochner, S. Freeman, K.B. Tan, K.T. Gallagher, K. D'Alessio, S.D. Holmes, J. Abrahamson, C.B. Hopson, E.I. Fischer, C.L. Erickson-Miller, H. Tachimoto, R.P. Schleimer, and J.R. White Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells and basophils J. Allergy Clin. Immunol. 105 2000 1093 1100
2. G. Foussias, G.M. Yousef, and E.P. Diamandis Molecular characterization of a Siglec-8 variant containing cytoplasmic tyrosine-based motifs, and mapping of the Siglec-8 gene Biochem. Biophys. Res. Commun. 278 2000 775 781
3. H. Floyd, J. Ni, A.L. Cornish, Z. Zeng, D. Liu, K.C. Carter, J. Steel, and P.R. Crocker Siglec-8: a novel eosinophil-specific member of the immunoglobulin superfamily J. Biol. Chem. 275 2000 861 866
4. P.R. Crocker, and A. Varki Siglecs, sialic acids and innate immunity Trends Immunol. 22 2001 337 342
5. E. Nutku, H. Aizawa, S.A. Hudson, and B.S. Bochner Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis Blood 101 2003 5014 5020
6. P.H. Krammer CD95(APO-1/Fas)-mediated apoptosis: live and let die Adv. Immunol. 71 1999 163 210
7. J.C. Reed The Survivin saga goes in vivo J. Clin. Invest. 108 2001 965 969
8. N.B. Blatt, and G.D. Glick Signaling pathways and effector mechanisms pre-programmed cell death Bioorg. Med. Chem. 9 2001 1371 1384
9. K. Matsumoto, R.P. Schleimer, H. Saito, Y. Iikura, and B.S. Bochner Induction of apoptosis in human eosinophils by anti-fas antibody treatment in vitro Blood 86 1995 1437 1443
10. D.L. Farkas, M.D. Wei, P. Febbroriello, J.H. Carson, and L.M. Loew Simultaneous imaging of cell and mitochondrial membrane potentials Biophys. J. 56 1989 1053 1069
11. G. Dewson, G.M. Cohen, and A.J. Wardlaw Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils Blood 98 2001 2239 2247
12. N. Zamzami, P. Marchetti, M. Castedo, C. Zanin, J.L. Vayssiere, P.X. Petit, and G. Kroemer Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo J. Exp. Med. 181 1995 1661 1672
13. C. Voisine, E.A. Craig, N. Zufall, O. von Ahsen, N. Pfanner, and W. Voos The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70 Cell 97 1999 565 574
14. J.E. Ricci, R.A. Gottlieb, and D.R. Green Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis J. Cell Biol. 160 2003 65 75
15. Q. Chen, E.J. Vazquez, S. Moghaddas, C.L. Hoppel, and E.J. Lesnefsky Production of reactive oxygen species by mitochondria: central role of complex III J. Biol. Chem. 278 2003 36027 36031
16. K. Sugioka, M. Nakano, H. Totsune-Nakano, H. Minakami, S. Tero-Kubota, and Y. Ikegami Mechanism of O2- generation in reduction and oxidation cycle of ubiquinones in a model of mitochondrial electron transport systems Biochim. Biophys. Acta 936 1988 377 385
17. J.F. Turrens, and A. Boveris Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria Biochem. J. 191 1980 421 427
18. S. Tan, Y. Sagara, Y. Liu, P. Maher, and D. Schubert The regulation of reactive oxygen species production during programmed cell death J. Cell Biol. 141 1998 1423 1432
19. A.K. Bhunia, H. Han, A. Snowden, and S. Chatterjee Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells J. Biol. Chem. 272 1997 15642 15649
20. K. Irani, Y. Xia, J.L. Zweier, S.J. Sollott, C.J. Der, E.R. Fearon, M. Sundaresan, T. Finkel, and P.J. Goldschmidt-Clermont Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts Science 275 1997 1649 1652
21. Y. Li, and M.A. Trush Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production Biochem. Biophys. Res. Commun. 253 1998 295 299
22. S. von Gunten, S. Yousefi, M. Seitz, S.M. Jakob, T. Schaffner, R. Seger, J. Takala, P.M. Villiger, and H.U. Simon Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment Blood 106 2005 1423 1431
23. E.A. Slee, C. Adrain, and S.J. Martin Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis J. Biol. Chem. 276 2001 7320 7326
24. A. Ashkenazi, and V.M. Dixit Death receptors: signaling and modulation Science 281 1998 1305 1308
25. X. Luo, I. Budihardjo, H. Zou, C. Slaughter, and X. Wang Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors Cell 94 1998 481 490
26. H. Li, H. Zhu, C.J. Xu, and J. Yuan Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 94 1998 491 501
27. S. Letuve, A. Druilhe, M. Grandsaigne, M. Aubier, and M. Pretolani Involvement of caspases and of mitochondria in Fas ligation-induced eosinophil apoptosis: modulation by interleukin-5 and interferon-gamma J. Leukoc. Biol. 70 2001 767 775
28. H.R. Stennicke, Q.L. Deveraux, E.W. Humke, J.C. Reed, V.M. Dixit, and G.S. Salvesen Caspase-9 can be activated without proteolytic processing J. Biol. Chem. 274 1999 8359 8362
29. E.A. Slee, M.T. Harte, R.M. Kluck, B.B. Wolf, C.A. Casiano, D.D. Newmeyer, H.G. Wang, J.C. Reed, D.W. Nicholson, E.S. Alnemri, D.R. Green, and S.J. Martin Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner J. Cell Biol. 144 1999 281 292
30. T. Hirsch, P. Marchetti, S.A. Susin, B. Dallaporta, N. Zamzami, I. Marzo, M. Geuskens, and G. Kroemer The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death Oncogene 15 1997 1573 1581
31. T. Hirsch, I. Marzo, and G. Kroemer Role of the mitochondrial permeability transition pore in apoptosis Biosci. Rep. 17 1997 67 76
32. P. Li, D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, E.S. Alnemri, and X. Wang Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 1997 479 489
33. S.A. Susin, H.K. Lorenzo, N. Zamzami, I. Marzo, B.E. Snow, G.M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D.R. Goodlett, R. Aebersold, D.P. Siderovski, J.M. Penninger, and G. Kroemer Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 1999 441 446
34. J. Zangrilli, N. Robertson, A. Shetty, J. Wu, A. Hastie, J.E. Fish, G. Litwack, and S.P. Peters Effect of IL-5, glucocorticoid, and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils Clin. Exp. Immunol. 120 2000 12 21
35. I. Kato, T. Takai, and A. Kudo The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB J. Immunol. 168 2002 629 634
36. K.L. Berg, K. Carlberg, L.R. Rohrschneider, K.A. Siminovitch, and E.R. Stanley The major SHP-1-binding, tyrosine-phosphorylated protein in macrophages is a member of the KIR/LIR family and an SHP-1 substrate Oncogene 17 1998 2535 2541
37. A. Kuroiwa, Y. Yamashita, M. Inui, T. Yuasa, M. Ono, A. Nagabukuro, Y. Matsuda, and T. Takai Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, and chromosomal assignment of the gene J. Biol. Chem. 273 1998 1070 1074