Antibiotic translocation through membrane channels: Temperature-dependent ion current fluctuation for catching the fast events

European Biophysics Journal

Volumn 38, Issue 8, 2009, Pages 1141-1145

  Mahendran, Kozhinjampara R ^a   Chimerel, Catalin ^a,b   MacH, Tivadar ^a   Winterhalter, Mathias ^a  

^a JACOBS UNIVERSITY BREMEN   (Germany)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Arrhenius; Ompf ampicillin translocation (nonspecific); Temperature

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; OUTER MEMBRANE PROTEIN F;

ARTICLE; ENERGY; ION CURRENT; MEMBRANE CHANNEL; MEMBRANE PERMEABILITY; NANOPORE; ROOM TEMPERATURE; TEMPERATURE DEPENDENCE;

AMPICILLIN; ANTI-BACTERIAL AGENTS; COMPUTER SIMULATION; ION CHANNEL GATING; LIPID BILAYERS; MEMBRANE POTENTIALS; MODELS, CHEMICAL; PORINS; TEMPERATURE;

ESCHERICHIA COLI;

EID: 70349669315     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-009-0495-0     Document Type: Article

References (32)

1. WR Bauer W Nadler 2006 Molecular transport through channels and pores: effects of in-channel interactions and blocking Proc Natl Acad Sci USA 103 11446 11451 10.1073/pnas.0601769103 16861303 10.1073/pnas.0601769103 1:CAS:528:DC%2BD28XotFegtL4%3D (Pubitemid 44182471)
2. AM Berezhkovskii SM Bezrukov 2005 Optimizing transport of metabolites through large channels: molecular sieves with and without binding Biophys J 88 L17 L19 10.1529/biophysj.104.057588 15626697 10.1529/biophysj.104.057588 1:CAS:528:DC%2BD2MXis1Whtrg%3D (Pubitemid 40976167)
3. AM Berezhkovskii MA Pustovoit SM Bezrukov 2002 Channel-facilitated membrane transport: transit probability and interaction with the channel J Chem Phys 116 9952 9956 10.1063/1.1475758 10.1063/1.1475758 1:CAS:528: DC%2BD38XjvF2gt7k%3D (Pubitemid 34690646)
4. AM Berezhkovskii MA Pustovoit SM Bezrukov 2002 Effect of binding on particle number fluctuations in a membrane channel J Chem Phys 116 6216 6220 10.1063/1.1458935 10.1063/1.1458935 1:CAS:528:DC%2BD38XisVCisL8%3D (Pubitemid 34476577)
5. J Bredin N Saint M Mallea E De G Molle JM Pagès V Simonet 2002 Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region Biochem J 363 521 528 10.1042/0264-6021: 3630521 11964152 10.1042/0264-6021:3630521 1:CAS:528:DC%2BD38XjvFenu7g%3D (Pubitemid 34526372)
6. M Ceccarelli C Danelon A Laio M Parrinello 2004 Microscopic mechanism of antibiotics translocation through a porin Biophys J 87 58 64 10.1529/biophysj.103.037283 15240444 10.1529/biophysj.103.037283 1:CAS:528:DC%2BD2cXmtVemtbc%3D (Pubitemid 38880064)
7. C Chimerel S Pezeshki M Winterhalter U Kleinekathöfer 2008 Transport at the nanoscale: temperature dependence of ion conductance Eur Biophys J 38 121 125 10.1007/s00249-008-0366-0 18726094 10.1007/s00249-008-0366-0 1:CAS:528:DC%2BD1cXhtlShurzL
8. Colquhoun D, Sigworth FJ (1983) Fitting and statistical analysis of single-channel records. In: Sakmann B, Neher E (eds) Single channel recording. Plenum Publishing Corp., New York, pp 191-263
9. J Comer V Dimitrov G Timp A Aksimentiev 2009 Microscopic mechanics of hairpin DNA translocation through synthetic nanopores Biophys J 96 593 608 10.1016/j.bpj.2008.09.023 19167307 10.1016/j.bpj.2008.09.023 1:CAS:528:DC%2BD1MXht12ktrw%3D
10. SW Cowan T Schirmer G Rummel M Steiert R Ghosh A Pauptit JN Jansonius JP Rosenbusch 1992 Crystal structures explain functional properties of two E. coli porins Nature 358 727 733 10.1038/358727a0 1380671 10.1038/358727a0 1:CAS:528:DyaK38XlsVGltbo%3D
11. C Danelon A Suenaga M Winterhalter I Yamato 2003 Molecular origin of the cation selectivity in OmpF porin. Single channel conductances versus free energy calculation Biophys Chem 104 591 603 10.1016/S0301-4622(03)00062-0 12914905 10.1016/S0301-4622(03)00062-0 1:CAS:528:DC%2BD3sXmt1GqtL8%3D (Pubitemid 36945578)
12. C Danelon T Brando M Winterhalter 2003 Probing the orientation of reconstituted maltoporin channels at the single-protein level J Biol Chem 278 35542 10.1074/jbc.M305434200 12835320 10.1074/jbc.M305434200 1:CAS:528:DC%2BD3sXntVajs70%3D (Pubitemid 37102326)
13. C Danelon EM Nestorovich, et al. 2006 Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation Biophys J 90 1617 1627 10.1529/biophysj.105.075192 16339889 10.1529/biophysj.105.075192 1:CAS:528:DC%2BD28XitVahtb8%3D
14. AG Hawkes A Jalali D Colquhoun 1990 The distribution of the apparent open times and shit times in a single channel record when brief events cannot be detected Philos Trans A 332 1627 511 538 10.1098/rsta.1990.0129
15. JB Heng A Aksimentiev C Ho P Marks YV Grinkova S Sligar K Schulten G Timp 2006 The electomechanics of DNA in a synthetic nanopore Biophys J 90 1098 1106 10.1529/biophysj.105.070672 16284270 10.1529/biophysj.105.070672 1:CAS:528:DC%2BD28XhtFGhsbg%3D
16. James CE, Mahendran KR, Molitor A, Bolla JM, Bessonov AN, Winterhalter M, Pagès JM (2009) How beta-lactam antibiotics enter bacteria: a dialogue with the porins. PLoS One 4:e5453. doi: 10.1371/journal.pone.0005453
17. Y Jung H Bayley L Movileanu 2006 Temperature-responsive protein pores J Am Chem Soc 128 15332 15340 10.1021/ja065827t 17117886 10.1021/ja065827t 1:CAS:528:DC%2BD28XhtFKlu77O (Pubitemid 44853544)
18. XF Kang L-Q Gu S Cheley H Bayley 2005 Single protein pores containing molecular adapters at high temperatures Angew Chem Int Ed 44 1495 1499 10.1002/anie.200461885 10.1002/anie.200461885 1:CAS:528:DC%2BD2MXit12gsrs%3D (Pubitemid 40460041)
19. T Mach P Neves E Spiga H Weingart M Winterhalter P Ruggerone M Ceccarelli P Gameiro 2008 Facilitated permeation of antibiotics across membrane channels-interaction of the quinolone moxifloxacin with the OmpF channel J Am Chem Soc 130 13301 13309 10.1021/ja803188c 18788798 10.1021/ja803188c 1:CAS:528:DC%2BD1cXhtFelt7bL
20. Saier MH Jr 2007 Active transport in communication, protection and nutrition J Mol Microbiol Biotechnol 12 161 164 10.1159/000099638 10.1159/000099638 (Pubitemid 46980125)
21. M Montal P Mueller 1972 Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties Proc Natl Acad Sci USA 69 3561 3566 10.1073/pnas.69.12.3561 4509315 10.1073/pnas.69.12.3561 1:CAS:528:DyaE3sXmvVGhtA%3D%3D
22. S Nekolla C Andersen R Benz 1994 Noise analysis of ion current through the open and the sugar-induced closed state of the LamB channel of Escherichia coli outer membrane: evaluation of the sugar binding kinetics to the channel interior Biophys J 66 1388 1397 10.1016/S0006-3495(94)80929-4 7520291 10.1016/S0006-3495(94)80929-4 1:CAS:528:DyaK2cXkslKgsbg%3D
23. EM Nestorovich C Danelon M Winterhalter SM Bezrukov 2002 Designed to penetrate time-resolved interaction of single antibiotic molecules with bacterial pores Proc Natl Acad Sci USA 99 9789 9794 10.1073/pnas.152206799 12119404 10.1073/pnas.152206799 1:CAS:528:DC%2BD38XlslKgs70%3D (Pubitemid 34831126)
24. EM Nestorovich TK Rostovtseva SM Bezrukov 2003 Residue ionization and ion transport through OmpF channels Biophys J 85 3718 3729 10.1016/S0006-3495(03) 74788-2 14645063 10.1016/S0006-3495(03)74788-2 1:CAS:528:DC%2BD3sXpvVams70%3D
25. H Nikaido 2003 Molecular basis of bacterial outer membrane permeability revisited Microbiol Mol Biol Rev 67 593 656 10.1128/MMBR.67.4.593-656.2003 14665678 10.1128/MMBR.67.4.593-656.2003 1:CAS:528:DC%2BD2cXmt1Sqsg%3D%3D (Pubitemid 37549772)
26. JM Pagès CE James M Winterhalter 2008 The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria Nat Rev Microbiol 6 893 903 10.1038/nrmicro1994 18997824 10.1038/nrmicro1994
27. PS Phale A Philippsen C Widmer VP Phale JP Rosenbusch T Schirmer 2001 Role of charged residues at the OmpF porin channel constriction probed by mutagenesis and simulation Biochemistry 40 6319 6325 10.1021/bi010046k 11371193 10.1021/bi010046k 1:CAS:528:DC%2BD3MXjtFGrsbg%3D (Pubitemid 32472720)
28. TK Rostovtseva EM Nestorovich SM Bezrukov 2002 Partitioning of differently sized poly (ethylene glycol) s into OmpF porin Biophys J 82 160 169 10.1016/S0006-3495(02)75383-6 11751305 10.1016/S0006-3495(02)75383-6 1:CAS:528:DC%2BD38XoslKlsA%3D%3D
29. G Schwarz C Danelon M Winterhalter 2003 On translocation through a membrane channel via an internal binding site: kinetics and voltage dependence Biophys J 84 2990 2998 10.1016/S0006-3495(03)70025-3 12719230 10.1016/S0006-3495(03)70025-3 1:CAS:528:DC%2BD3sXjvFGjtLc%3D
30. M Wanunu J Sutin B McNally A Chow A Mellar 2008 DNA translocation governed by interactions with solid-state nanopores Biophys J 95 4716 4725 10.1529/biophysj.108.140475 18708467 10.1529/biophysj.108.140475 1:CAS:528:DC%2BD1cXhtlOqtLnM
31. H Weingart M Petrescu M Winterhalter 2008 Biophysical characterization of in- and efflux in Gram-negative bacteria Curr Drug Targets 9 789 796 10.2174/138945008785747752 18781924 10.2174/138945008785747752 1:CAS:528:DC%2BD1cXhtVyltLfP
32. F Yoshimura H Nikaido 1985 Diffusion of beta-lactam antibiotics through the porin channels of Escherichia coli K-12 Antimicrob Agents Chemother 27 84 92 2580479 1:CAS:528:DyaL2MXhs1ahtbg%3D