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Volumn 22, Issue 5, 2009, Pages 500-505

Muscle atrophy in immobilization and senescence in humans

Author keywords

Atrophy; Growth; Limb immobilization; Muscle protein degradation; Muscle protein synthesis; Sarcopenia

Indexed keywords

MESSENGER RNA; MUSCLE RING FINGER 1 PROTEIN;

EID: 70349660067     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/WCO.0b013e32832f15e1     Document Type: Review
Times cited : (15)

References (43)
  • 1
    • 56449103294 scopus 로고    scopus 로고
    • A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle
    • Crossland H, Constantin-Teodosiu D, Gardiner S, et al. A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. J Physiol 2008; 586:5589-5600.
    • (2008) J Physiol , vol.586 , pp. 5589-5600
    • Crossland, H.1    Constantin-Teodosiu, D.2    Gardiner, S.3
  • 2
    • 58149307451 scopus 로고    scopus 로고
    • Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy
    • Mallinson J, Constantin-Teodosiu D, Sidaway J, et al. Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy. J Physiol 2009; 587:219-230.
    • (2009) J Physiol , vol.587 , pp. 219-230
    • Mallinson, J.1    Constantin-Teodosiu, D.2    Sidaway, J.3
  • 3
    • 11144356337 scopus 로고    scopus 로고
    • Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • Sandri M, Sandri C, Gilbert A, et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 2004; 117:399-412.
    • (2004) Cell , vol.117 , pp. 399-412
    • Sandri, M.1    Sandri, C.2    Gilbert, A.3
  • 4
    • 2042425906 scopus 로고    scopus 로고
    • The IGF-1/PI3K/Akt pathway prevents short article expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
    • Stitt TN, Drujan D, Clarke BA, et al. The IGF-1/PI3K/Akt pathway prevents short article expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 2004; 14:395-403.
    • (2004) Mol Cell , vol.14 , pp. 395-403
    • Stitt, T.N.1    Drujan, D.2    Clarke, B.A.3
  • 5
    • 42649112409 scopus 로고    scopus 로고
    • Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34
    • Gulati P, Gaspers L, Dann S, et al. Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Cell Metab 2008; 7:456-465.
    • (2008) Cell Metab , vol.7 , pp. 456-465
    • Gulati, P.1    Gaspers, L.2    Dann, S.3
  • 6
    • 53149125147 scopus 로고    scopus 로고
    • Disassociation between the effects of amino acids and insulin on signalling, ubiquitin-ligases and protein turnover in human muscle
    • Greenhaff P, Karagounis L, Peirce N, et al. Disassociation between the effects of amino acids and insulin on signalling, ubiquitin-ligases and protein turnover in human muscle. Am J Physiol Endocrinol Metab 2008; 295:E595-E731.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Greenhaff, P.1    Karagounis, L.2    Peirce, N.3
  • 7
    • 0035941020 scopus 로고    scopus 로고
    • Identification of ubiquitin ligases required for skeletal muscle atrophy
    • Bodine SC, Latres E, Baumhueter S, et al. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 2001; 294:1704-1708.
    • (2001) Science , vol.294 , pp. 1704-1708
    • Bodine, S.C.1    Latres, E.2    Baumhueter, S.3
  • 8
    • 0347285363 scopus 로고    scopus 로고
    • Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
    • Lecker SH, Jagoe RT, Gilbert A, et al. Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 2004; 18:39-51.
    • (2004) FASEB J , vol.18 , pp. 39-51
    • Lecker, S.H.1    Jagoe, R.T.2    Gilbert, A.3
  • 9
    • 48549107440 scopus 로고    scopus 로고
    • Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
    • Wilkinson S, Phillips S, Atherton P, et al. Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol 2008; 586:3701-3717.
    • (2008) J Physiol , vol.586 , pp. 3701-3717
    • Wilkinson, S.1    Phillips, S.2    Atherton, P.3
  • 10
    • 63849130621 scopus 로고    scopus 로고
    • Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis
    • Drummond M, Fry C, Glynn E, et al. Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. J Physiol 2009; 587:1535-1546.
    • (2009) J Physiol , vol.587 , pp. 1535-1546
    • Drummond, M.1    Fry, C.2    Glynn, E.3
  • 11
    • 6944226810 scopus 로고    scopus 로고
    • Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass
    • Jones S, Hill R, Krasney P, et al. Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass. FASEB J 2004; 18:1025-1027.
    • (2004) FASEB J , vol.18 , pp. 1025-1027
    • Jones, S.1    Hill, R.2    Krasney, P.3
  • 12
    • 34548769347 scopus 로고    scopus 로고
    • Time course of muscular, neural and tendinous adaptations to 23 day unilateral lower-limb suspension in young men
    • de Boer M, Maganaris C, Seynnes O, et al. Time course of muscular, neural and tendinous adaptations to 23 day unilateral lower-limb suspension in young men. J Physiol 2007; 583:1079-1091.
    • (2007) J Physiol , vol.583 , pp. 1079-1091
    • De Boer, M.1    Maganaris, C.2    Seynnes, O.3
  • 13
    • 58149502082 scopus 로고    scopus 로고
    • Restoration of voluntary muscle strength after 3 weeks of cast immobilization is suppressed in women compared with men
    • Clark B, Manini T, Hoffman R, Russ D. Restoration of voluntary muscle strength after 3 weeks of cast immobilization is suppressed in women compared with men. Arch Phys Med Rehabil 2009; 90:178-180.
    • (2009) Arch Phys Med Rehabil , vol.90 , pp. 178-180
    • Clark, B.1    Manini, T.2    Hoffman, R.3    Russ, D.4
  • 14
    • 36248952729 scopus 로고    scopus 로고
    • The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse
    • de Boer M, Selby A, Atherton P, et al. The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse. J Physiol 2007; 585:241-251.
    • (2007) J Physiol , vol.585 , pp. 241-251
    • De Boer, M.1    Selby, A.2    Atherton, P.3
  • 15
    • 57649232182 scopus 로고    scopus 로고
    • Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
    • Glover E, Phillips S, Oates B, et al. Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion. J Physiol 2008; 586:6049-6061.
    • (2008) J Physiol , vol.586 , pp. 6049-6061
    • Glover, E.1    Phillips, S.2    Oates, B.3
  • 16
    • 24744466753 scopus 로고    scopus 로고
    • Of mice and men: When it comes to studying ageing and the means to slow it down, mice are not just small humans
    • Demetrius L. Of mice and men: when it comes to studying ageing and the means to slow it down, mice are not just small humans. EMBO Rep 2005; 6:S39-S44.
    • (2005) EMBO Rep , vol.6
    • Demetrius, L.1
  • 17
    • 36248937816 scopus 로고    scopus 로고
    • Transcriptional pathways associated with skeletal muscle disuse atrophy in humans
    • Chen Y, Gregory C, Scarborough M, et al. Transcriptional pathways associated with skeletal muscle disuse atrophy in humans. Physiol Genomics 2007; 31:510-520.
    • (2007) Physiol Genomics , vol.31 , pp. 510-520
    • Chen, Y.1    Gregory, C.2    Scarborough, M.3
  • 18
    • 33749380054 scopus 로고    scopus 로고
    • Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest
    • Ogawa T, Furochi H, Mameoka M, et al. Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest. Muscle Nerve 2006; 34:463-469.
    • (2006) Muscle Nerve , vol.34 , pp. 463-469
    • Ogawa, T.1    Furochi, H.2    Mameoka, M.3
  • 19
    • 53049104983 scopus 로고    scopus 로고
    • Skeletal muscle proteolysis in response to short-term unloading in humans
    • Tesch P, von Walden F, Gustafsson T, et al. Skeletal muscle proteolysis in response to short-term unloading in humans. J Appl Physiol 2008; 105:902-906.
    • (2008) J Appl Physiol , vol.105 , pp. 902-906
    • Tesch, P.1    Von Walden, F.2    Gustafsson, T.3
  • 20
    • 55449120287 scopus 로고    scopus 로고
    • Reliability of results and interpretation of measures of 3-methylhistidine in muscle interstitium as marker of muscle proteolysis
    • Rennie M, Phillips S, Smith K. Reliability of results and interpretation of measures of 3-methylhistidine in muscle interstitium as marker of muscle proteolysis. J Appl Physiol 2008; 105:1380-1381.
    • (2008) J Appl Physiol , vol.105 , pp. 1380-1381
    • Rennie, M.1    Phillips, S.2    Smith, K.3
  • 22
    • 66149124537 scopus 로고    scopus 로고
    • Exercise in space: Human skeletal muscle after 6 months aboard the International Space Station
    • Trappe S, Costill D, Gallagher P, et al. Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. J Appl Physiol 2009; 106:1159-1168.
    • (2009) J Appl Physiol , vol.106 , pp. 1159-1168
    • Trappe, S.1    Costill, D.2    Gallagher, P.3
  • 23
    • 24144485840 scopus 로고    scopus 로고
    • Effects of 84-days of bedrest and resistance training on single muscle fibre myosin heavy chain distribution in human vastus lateralis and soleus muscles
    • Gallagher P, Trappe S, Harber M, et al. Effects of 84-days of bedrest and resistance training on single muscle fibre myosin heavy chain distribution in human vastus lateralis and soleus muscles. Acta Physiol Scand 2005; 185:61-69.
    • (2005) Acta Physiol Scand , vol.185 , pp. 61-69
    • Gallagher, P.1    Trappe, S.2    Harber, M.3
  • 24
    • 8844280111 scopus 로고    scopus 로고
    • Knee extensor and plantar flexor muscle size and function following 90 days of bed rest with or without resistance exercise
    • Alkner B, Tesch P. Knee extensor and plantar flexor muscle size and function following 90 days of bed rest with or without resistance exercise. Eur J Appl Physiol 2004; 93:294-305.
    • (2004) Eur J Appl Physiol , vol.93 , pp. 294-305
    • Alkner, B.1    Tesch, P.2
  • 25
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron A, Lawler A, Lee S. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 1997; 387:83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.1    Lawler, A.2    Lee, S.3
  • 26
    • 66349104285 scopus 로고    scopus 로고
    • Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men
    • Hulmi J, Tannerstedt J, Selanne H, et al. Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men. J Appl Physiol 2009; 106:1720-1729.
    • (2009) J Appl Physiol , vol.106 , pp. 1720-1729
    • Hulmi, J.1    Tannerstedt, J.2    Selanne, H.3
  • 27
    • 67650733280 scopus 로고    scopus 로고
    • Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression
    • [Epub ahead of print]. doi: 10.1007/ s00726-008-0150-156
    • Hulmi J, Kovanen V, Selänne H, et al. Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids 2008 [Epub ahead of print]. doi: 10.1007/ s00726-008-0150-156
    • (2008) Amino Acids
    • Hulmi, J.1    Kovanen, V.2    Selänne, H.3
  • 28
    • 66149166062 scopus 로고    scopus 로고
    • Strength training the free limb attenuates strength loss during unilateral immobilization
    • Farthing J, Krentz J, Magnus C. Strength training the free limb attenuates strength loss during unilateral immobilization. J Appl Physiol 2009; 106:830-836.
    • (2009) J Appl Physiol , vol.106 , pp. 830-836
    • Farthing, J.1    Krentz, J.2    Magnus, C.3
  • 29
    • 53449102100 scopus 로고    scopus 로고
    • Muscle fiber size and function in elderly humans: A longitudinal study
    • Frontera W, Reid K, Phillips E, et al. Muscle fiber size and function in elderly humans: a longitudinal study. J Appl Physiol 2008; 105:637-642.
    • (2008) J Appl Physiol , vol.105 , pp. 637-642
    • Frontera, W.1    Reid, K.2    Phillips, E.3
  • 30
    • 0035850407 scopus 로고    scopus 로고
    • Basal muscle amino acid kinetics and protein synthesis in healthy young and older men
    • Volpi E, Sheffield-Moore M, Rasmussen B, Wolfe R. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA 2001; 286:1206-1212.
    • (2001) JAMA , vol.286 , pp. 1206-1212
    • Volpi, E.1    Sheffield-Moore, M.2    Rasmussen, B.3    Wolfe, R.4
  • 31
    • 46749092047 scopus 로고    scopus 로고
    • Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women
    • Smith G, Atherton P, Villareal D, et al. Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women. PLoS ONE 2008; 3:e1875.
    • (2008) PLoS ONE , vol.3
    • Smith, G.1    Atherton, P.2    Villareal, D.3
  • 32
    • 66349103681 scopus 로고    scopus 로고
    • Exercise training and protein metabolism: Influences of contraction, protein intake, and sex-based differences
    • Burd N, Tang J, Moore D, Phillips S. Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences. J Appl Physiol 2009; 106:1692-1701.
    • (2009) J Appl Physiol , vol.106 , pp. 1692-1701
    • Burd, N.1    Tang, J.2    Moore, D.3    Phillips, S.4
  • 33
    • 14644444464 scopus 로고    scopus 로고
    • Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
    • Cuthbertson D, Smith K, Babraj J, et al. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J 2005; 19:422-424.
    • (2005) FASEB J , vol.19 , pp. 422-424
    • Cuthbertson, D.1    Smith, K.2    Babraj, J.3
  • 34
  • 35
    • 0042068305 scopus 로고    scopus 로고
    • Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults
    • Volpi E, Kobayashi H, Sheffield-Moore M, et al. Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr 2003; 78:250-258.
    • (2003) Am J Clin Nutr , vol.78 , pp. 250-258
    • Volpi, E.1    Kobayashi, H.2    Sheffield-Moore, M.3
  • 36
    • 45149131733 scopus 로고    scopus 로고
    • Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
    • Drummond M, Dreyer H, Pennings B, et al. Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging. J Appl Physiol 2008; 104:1452-1461.
    • (2008) J Appl Physiol , vol.104 , pp. 1452-1461
    • Drummond, M.1    Dreyer, H.2    Pennings, B.3
  • 37
    • 44449084604 scopus 로고    scopus 로고
    • Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia
    • Solerte S, Gazzaruso C, Bonacasa R, et al. Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia. Am J Cardiol 2008; 101:69E-77E.
    • (2008) Am J Cardiol , vol.101
    • Solerte, S.1    Gazzaruso, C.2    Bonacasa, R.3
  • 38
    • 66149116366 scopus 로고    scopus 로고
    • Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis
    • Drummond M, Miyazaki M, Dreyer H, et al. Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis. J Appl Physiol 2009; 106:1403-1411.
    • (2009) J Appl Physiol , vol.106 , pp. 1403-1411
    • Drummond, M.1    Miyazaki, M.2    Dreyer, H.3
  • 39
    • 58149307453 scopus 로고    scopus 로고
    • Age-related differences in the doseresponse relationship of muscle protein synthesis to resistance exercise in young and old men
    • Kumar V, Selby A, Rankin D, et al. Age-related differences in the doseresponse relationship of muscle protein synthesis to resistance exercise in young and old men. J Physiol 2009; 587:211-217.
    • (2009) J Physiol , vol.587 , pp. 211-217
    • Kumar, V.1    Selby, A.2    Rankin, D.3
  • 40
    • 59649122217 scopus 로고    scopus 로고
    • Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men
    • Verdijk L, Jonkers R, Gleeson B, et al. Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. Am J Clin Nutr 2009; 89:608-616.
    • (2009) Am J Clin Nutr , vol.89 , pp. 608-616
    • Verdijk, L.1    Jonkers, R.2    Gleeson, B.3
  • 41
    • 46749089596 scopus 로고    scopus 로고
    • Proteasome activities in the rectus abdominis muscle of young and older individuals
    • Bossola M, Pacelli F, Costelli P, et al. Proteasome activities in the rectus abdominis muscle of young and older individuals. Biogerontology 2008; 9:261-268.
    • (2008) Biogerontology , vol.9 , pp. 261-268
    • Bossola, M.1    Pacelli, F.2    Costelli, P.3
  • 42
    • 39449100832 scopus 로고    scopus 로고
    • Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation
    • Lé ger B, Derave W, De Bock K, et al. Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation. Rejuvenation Res 2008; 11:163-175.
    • (2008) Rejuvenation Res , vol.11 , pp. 163-175
    • Léger, B.1    Derave, W.2    De Bock, K.3
  • 43
    • 38749140252 scopus 로고    scopus 로고
    • Proteolytic gene expression differs at rest and after resistance exercise between young and old women
    • Raue U, Slivka D, Jemiolo B, et al. Proteolytic gene expression differs at rest and after resistance exercise between young and old women. J Gerontol A Biol Sci Med Sci 2007; 62:1407-1412.
    • (2007) J Gerontol A Biol Sci Med Sci , vol.62 , pp. 1407-1412
    • Raue, U.1    Slivka, D.2    Jemiolo, B.3


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