메뉴 건너뛰기




Volumn 65, Issue 1, 2009, Pages 191-195

The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer

Author keywords

Bevacizumab; Cancer therapy; Cisplatin; PG11047; Polyamine analog

Indexed keywords

BEVACIZUMAB; CISPLATIN; PG 11047; POLYAMINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 70349621130     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-009-1105-7     Document Type: Article
Times cited : (23)

References (25)
  • 1
    • 0019469747 scopus 로고
    • Role of polyamines in the control of cell proliferation and differentiation
    • DOI 10.1111/j.1432-0436.1981.tb01123.x
    • O Heby 1981 Role of polyamines in the control of cell proliferation and differentiation Differentiation 19 1 20 6173280 10.1111/j.1432-0436.1981. tb01123.x 1:CAS:528:DyaL3MXktlOht7w%3D (Pubitemid 11091193)
    • (1981) Differentiation , vol.19 , Issue.1 , pp. 1-20
    • Heby, O.1
  • 2
    • 0025873423 scopus 로고
    • Polyamines: From molecular biology to clinical applications
    • 1930914 10.3109/07853899109148056 1:CAS:528:DyaK3MXmslemsbo%3D
    • J Janne L Alhonen P Leinonen 1991 Polyamines: from molecular biology to clinical applications Ann Med 23 241 259 1930914 10.3109/07853899109148056 1:CAS:528:DyaK3MXmslemsbo%3D
    • (1991) Ann Med , vol.23 , pp. 241-259
    • Janne, J.1    Alhonen, L.2    Leinonen, P.3
  • 3
    • 0021155448 scopus 로고
    • Polyamines
    • 6206782 10.1146/annurev.bi.53.070184.003533 1:CAS:528:DyaL2cXlt1Cqtb0%3D
    • CW Tabor H Tabor 1984 Polyamines Annu Rev Biochem 53 749 790 6206782 10.1146/annurev.bi.53.070184.003533 1:CAS:528:DyaL2cXlt1Cqtb0%3D
    • (1984) Annu Rev Biochem , vol.53 , pp. 749-790
    • Tabor, C.W.1    Tabor, H.2
  • 4
    • 0034685624 scopus 로고    scopus 로고
    • Polyamines: Mysterious modulators of cellular functions
    • DOI 10.1006/bbrc.2000.2601
    • K Igarashi K Kashiwagi 2000 Polyamines: mysterious modulators of cellular functions Biochem Biophys Res Commun 271 559 564 10814501 10.1006/bbrc.2000. 2601 1:CAS:528:DC%2BD3cXjt1SjsrY%3D (Pubitemid 30444667)
    • (2000) Biochemical and Biophysical Research Communications , vol.271 , Issue.3 , pp. 559-564
    • Igarashi, K.1    Kashiwagi, K.2
  • 5
    • 0028831608 scopus 로고
    • Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme
    • 7813017 10.1016/0092-8674(95)90450-6 1:CAS:528:DyaK2MXjtFegur4%3D
    • S Matsufuji T Matsufuji Y Miyazaki, et al. 1995 Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme Cell 80 51 60 7813017 10.1016/0092-8674(95)90450-6 1:CAS:528:DyaK2MXjtFegur4%3D
    • (1995) Cell , vol.80 , pp. 51-60
    • Matsufuji, S.1    Matsufuji, T.2    Miyazaki, Y.3
  • 6
    • 34248228763 scopus 로고    scopus 로고
    • Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
    • DOI 10.1038/nrd2243, PII NRD2243
    • RA Casero Jr LJ Marton 2007 Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases Nat Rev Drug Discov 6 373 390 17464296 10.1038/nrd2243 1:CAS:528:DC%2BD2sXkslyiu7k%3D (Pubitemid 46705201)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.5 , pp. 373-390
    • Casero, R.A.1    Marton, L.J.2
  • 7
    • 20444422472 scopus 로고    scopus 로고
    • Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy
    • DOI 10.1016/j.pharmthera.2005.02.001, PII S0163725805000380
    • N Seiler 2005 Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy Pharmacol Ther 107 99 119 15963353 10.1016/j.pharmthera.2005.02.001 1:CAS:528:DC%2BD2MXlt1Ghu78%3D (Pubitemid 40803509)
    • (2005) Pharmacology and Therapeutics , vol.107 , Issue.1 , pp. 99-119
    • Seiler, N.1
  • 8
    • 0032547998 scopus 로고    scopus 로고
    • 12N-bisethylspermine: Synthesis and growth inhibitory effects on human tumor cell lines
    • DOI 10.1021/jm980172v
    • VK Reddy A Valasinas A Sarkar, et al. 1998 Conformationally restricted analogues of 1N, 12N-bisethylspermine: synthesis and growth inhibitory effects on human tumor cell lines J Med Chem 41 4723 4732 9822543 10.1021/jm980172v 1:CAS:528:DyaK1cXmvVaqt7k%3D (Pubitemid 28530449)
    • (1998) Journal of Medicinal Chemistry , vol.41 , Issue.24 , pp. 4723-4732
    • Reddy, V.K.1    Valasinas, A.2    Sarkar, A.3    Basu, H.S.4    Marton, L.J.5    Frydman, B.6
  • 9
    • 0035254215 scopus 로고    scopus 로고
    • 14N-bisethylhomospermine (BE-4-4-4): Synthesis and growth inhibitory effects on human prostate cancer cells
    • DOI 10.1021/jm000309t
    • A Valasinas A Sarkar VK Reddy, et al. 2001 Conformationally restricted analogues of 1N, 14N-bisethylhomospermine (BE-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells J Med Chem 44 390 403 11462979 10.1021/jm000309t 1:CAS:528:DC%2BD3cXovVWmsr4%3D (Pubitemid 32113585)
    • (2001) Journal of Medicinal Chemistry , vol.44 , Issue.3 , pp. 390-403
    • Valasinas, A.1    Sarkar, A.2    Reddy, V.K.3    Marton, L.J.4    Basu, H.S.5    Frydman, B.6
  • 10
    • 14144251611 scopus 로고    scopus 로고
    • Molecular mechanisms of polyamine analogs in cancer cells
    • DOI 10.1097/00001813-200503000-00002
    • Y Huang A Pledgie RA Casero, et al. 2005 Molecular mechanisms of polyamine analogs in cancer cells Anticancer Drugs 16 229 241 15711175 10.1097/00001813-200503000-00002 1:CAS:528:DC%2BD2MXht1Omsbk%3D (Pubitemid 40283938)
    • (2005) Anti-Cancer Drugs , vol.16 , Issue.3 , pp. 229-241
    • Huang, Y.1    Pledgie, A.2    Casero Jr., R.A.3    Davidson, N.E.4
  • 11
    • 33646597294 scopus 로고    scopus 로고
    • Differential polyamine analogue effects in four human breast cancer cell lines
    • DOI 10.1016/j.tox.2006.03.009, PII S0300483X06001557
    • CM Holst B Frydman LJ Marton SM Oredsson 2006 Differential polyamine analogue effects in four human breast cancer cell lines Toxicology 223 71 81 16697514 10.1016/j.tox.2006.03.009 1:CAS:528:DC%2BD28XkvVynt7o%3D (Pubitemid 43728619)
    • (2006) Toxicology , vol.223 , Issue.1-2 , pp. 71-81
    • Holst, C.M.1    Frydman, B.2    Marton, L.J.3    Oredsson, S.M.4
  • 12
    • 53149113412 scopus 로고    scopus 로고
    • In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells
    • 18301893 10.1007/s00280-008-0706-x 1:CAS:528:DC%2BD1cXhtF2kur7P
    • A Hacker LJ Marton M Sobolewski RA Casero Jr 2008 In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells Cancer Chemother Pharmacol 63 1 45 53 18301893 10.1007/s00280-008-0706-x 1:CAS:528:DC%2BD1cXhtF2kur7P
    • (2008) Cancer Chemother Pharmacol , vol.63 , Issue.1 , pp. 45-53
    • Hacker, A.1    Marton, L.J.2    Sobolewski, M.3    Casero Jr, R.A.4
  • 13
    • 34547691625 scopus 로고    scopus 로고
    • Antizyme and antizyme inhibitor activities influence cellular responses to polyamine analogs
    • DOI 10.1007/s00726-007-0523-2, Special Issue: Polyamines and their Analogs in Cancer and other Diseases
    • JL Mitchell TK Thane JM Sequeira, et al. 2007 Antizyme and antizyme inhibitor activities influence cellular responses to polyamine analogs Amino Acids 33 291 297 17410332 10.1007/s00726-007-0523-2 1:CAS:528: DC%2BD2sXos1eqtrY%3D (Pubitemid 47222969)
    • (2007) Amino Acids , vol.33 , Issue.2 , pp. 291-297
    • Mitchell, J.L.A.1    Thane, T.K.2    Sequeira, J.M.3    Marton, L.J.4    Thokala, R.5
  • 15
    • 0035878846 scopus 로고    scopus 로고
    • Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure
    • 11454677 1:CAS:528:DC%2BD3MXlsVChsrk%3D
    • Y Wang W Devereux PM Woster 2001 Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure Cancer Res 61 5370 5373 11454677 1:CAS:528:DC%2BD3MXlsVChsrk%3D
    • (2001) Cancer Res , vol.61 , pp. 5370-5373
    • Wang, Y.1    Devereux, W.2    Woster, P.M.3
  • 18
    • 0030052627 scopus 로고    scopus 로고
    • Synergism of the polyamine analogue, N1, N11-bisethylnorspermine with cis-diaminedichloroplatinum (II) against murine neoplastic cell lines in vitro and in vivo
    • 10.1016/0304-3835(95)04043-9
    • TR Hawthorn JK Austin Jr 1996 Synergism of the polyamine analogue, N1, N11-bisethylnorspermine with cis-diaminedichloroplatinum (II) against murine neoplastic cell lines in vitro and in vivo Cancer Lett 99 1 99 107 10.1016/0304-3835(95)04043-9
    • (1996) Cancer Lett , vol.99 , Issue.1 , pp. 99-107
    • Hawthorn, T.R.1    Austin Jr, J.K.2
  • 19
    • 56449109565 scopus 로고    scopus 로고
    • Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase
    • 19010902 10.1158/0008-5472.CAN-08-2340 1:CAS:528:DC%2BD1cXhtlOmt7rL
    • KJ Svensson JE Welch P Kucharzewska 2008 Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase Cancer Res 68 22 9291 9301 19010902 10.1158/0008-5472.CAN-08-2340 1:CAS:528:DC%2BD1cXhtlOmt7rL
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9291-9301
    • Svensson, K.J.1    Welch, J.E.2    Kucharzewska, P.3
  • 20
    • 0345688128 scopus 로고    scopus 로고
    • A perspective of polyamine metabolism
    • DOI 10.1042/BJ20031327
    • HM Wallace AV Fraser A Hughes 2003 A perspective of polyamine metabolism Biochem J 376 1 14 13678416 10.1042/BJ20031327 1:CAS:528:DC%2BD3sXovVajs7Y%3D (Pubitemid 37487199)
    • (2003) Biochemical Journal , vol.376 , Issue.1 , pp. 1-14
    • Wallace, H.M.1    Fraser, A.V.2    Hughes, A.3
  • 21
    • 33644863498 scopus 로고    scopus 로고
    • Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF
    • 16278208 10.1074/jbc.M508199200 1:CAS:528:DC%2BD28Xit1Witw%3D%3D
    • WC Liang X Wu FV Peale, et al. 2006 Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF J Biol Chem 281 2 951 961 16278208 10.1074/jbc.M508199200 1:CAS:528:DC%2BD28Xit1Witw%3D%3D
    • (2006) J Biol Chem , vol.281 , Issue.2 , pp. 951-961
    • Liang, W.C.1    Wu, X.2    Peale, F.V.3
  • 23
    • 33947320115 scopus 로고    scopus 로고
    • Platinum drug effects on the expression of genes in the polyamine pathway: Time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells
    • DOI 10.1007/s00280-006-0325-3
    • R Varma S Hector WR Greco, et al. 2007 Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells Cancer Chemother Pharmacol 59 711 723 17021820 10.1007/s00280-006-0325-3 1:CAS:528:DC%2BD2sXjt1WmtL0%3D (Pubitemid 46440593)
    • (2007) Cancer Chemotherapy and Pharmacology , vol.59 , Issue.6 , pp. 711-723
    • Varma, R.1    Hector, S.2    Greco, W.R.3    Clark, K.4    Hawthorn, L.5    Porter, C.6    Pendyala, L.7
  • 24
    • 0028998931 scopus 로고
    • Vascular endothelial cell proliferation: Regulation of cellular polyamines
    • 7656288 1:CAS:528:DyaK2MXnt1eqt7s%3D
    • RF Morrison ER Seidel 1995 Vascular endothelial cell proliferation: regulation of cellular polyamines Cardiovasc Res 29 841 847 7656288 1:CAS:528:DyaK2MXnt1eqt7s%3D
    • (1995) Cardiovasc Res , vol.29 , pp. 841-847
    • Morrison, R.F.1    Seidel, E.R.2
  • 25
    • 49649129997 scopus 로고    scopus 로고
    • The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib
    • 18559525 10.1158/0008-5472.CAN-07-6483 1:CAS:528:DC%2BD1cXnt1ejs7g%3D
    • JS Carew ST Nawrocki VK Reddy, et al. 2008 The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib Cancer Res 68 4783 4790 18559525 10.1158/0008-5472.CAN-07-6483 1:CAS:528:DC%2BD1cXnt1ejs7g%3D
    • (2008) Cancer Res , vol.68 , pp. 4783-4790
    • Carew, J.S.1    Nawrocki, S.T.2    Reddy, V.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.