Pharmacological stimulation of soluble guanylate cyclase modulates hypoxia-inducible factor-1α in rat heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 297, Issue 4, 2009, Pages

  Tsuruda, Toshihiro ^a   Hatakeyama, Kinta ^b   Masuyama, Hiroyuki ^a   Sekita, Yoko ^a   Imamura, Takuroh ^a   Asada, Yujiro ^b   Kitamura, Kazuo ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Angiogenesis; Cyclic guanosine monophosphate; Hypoxia; Inflammation; Mechanical load

Indexed keywords

4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; 8 BROMO CYCLIC GMP; CARBON DIOXIDE; CYCLIC GMP; GUANYLATE CYCLASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KT 5823; OXYGEN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CAPILLARY; CELL CULTURE; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART WORK; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SECOND MESSENGER;

ANIMALS; ANIMALS, NEWBORN; CARBAZOLES; CARDIOMEGALY; CELL HYPOXIA; CELLS, CULTURED; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME ACTIVATORS; GUANYLATE CYCLASE; HYPERTENSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MYOCYTES, CARDIAC; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SECOND MESSENGER SYSTEMS; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VENTRICULAR REMODELING;

EID: 70349617852     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00503.2009     Document Type: Article

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