High and Low Gain Switches for Regulation of cAMP Efflux Concentration: Distinct Roles for Particulate GC- and Soluble GC-cGMP-PDE3 Signaling in Rabbit Atria

Circulation Research

Volumn 94, Issue 7, 2004, Pages 936-943

  Wen, Jin Fu ^a   Cui, Xun ^a   Jin, Jing Yu ^a   Kim, Soo Mi ^a   Kim, Sung Zoo ^a   Kim, Suhn Hee ^a   Lee, Ho Sub ^b   Cho, Kyung Woo ^a,c  

^a Chonbuk National University Medical School   (South Korea)

^b Wonkwang University   (South Korea)

^c Chonbuk National University   (South Korea)

Author keywords

Atrial natriuretic peptide; cAMP; cGMP; Guanylyl cyclase; Phosphodiesterase 3

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; ATRIAL NATRIURETIC FACTOR; CYCLIC AMP; CYCLIC GMP; GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; LINSIDOMINE; MILRINONE; NATRIURETIC PEPTIDE TYPE C; NITRIC OXIDE DONOR; PHOSPHODIESTERASE III; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART ATRIUM; HEART ATRIUM CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE PERFUSION; HEART STROKE VOLUME; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RABBIT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE LEVEL; TRANSPORT KINETICS;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ADENINE; ANIMALS; ATRIAL NATRIURETIC FACTOR; BIOLOGICAL TRANSPORT; CARDIAC PACING, ARTIFICIAL; CYCLIC AMP; CYCLIC GMP; ENZYME INHIBITORS; GUANYLATE CYCLASE; HEART ATRIA; MILRINONE; MOLSIDOMINE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, C-TYPE; NITRIC OXIDE DONORS; OXADIAZOLES; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PYRAZOLES; PYRIDINES; QUINOXALINES; RABBITS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SECOND MESSENGER SYSTEMS; STROKE VOLUME;

EID: 1842863225     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000123826.70125.4D     Document Type: Article

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