Atopic sensitization during the first year of life in relation to long chain polyunsaturated fatty acid levels in human milk

Pediatric Research

Volumn 44, Issue 4, 1998, Pages 478-484

  Duchén, Karel ^a,b   Yu, Gu ^a   Björkstén, Bengt ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

POLYUNSATURATED FATTY ACID;

ADULT; AMINO ACID METABOLISM; ARTICLE; ATOPY; BREAST FEEDING; CELL PROLIFERATION; CLINICAL ARTICLE; COLOSTRUM; ENZYME ACTIVITY; FEMALE; HUMAN; INFANT; LIPID COMPOSITION; MALE; MILK; MILK ALLERGY; MONONUCLEAR CELL; PRIORITY JOURNAL; SENSITIZATION;

EID: 0031671302     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199810000-00003     Document Type: Article

References (40)

1. Simopoulos AP 1991 Omega-3 fatty acids in health and disease and in growth and development. Am J Clin Nutr 54:438-463
2. Hagve TA 1988 Effects of unsaturated fatty acids on cell membrane functions. Scand J Clin Lab Invest 48:381-388
3. Needleman P, Turk J, Jakschik BA, Morrison AR, Lefkowith JB 1986 LA metabolism. Annu Rev Biochem 55:69-102
4. Endres S, Eisenhut T, Sinha B 1995 n-3 polyunsaturated fatty acids in the regulation of human cytokine synthesis. In: Rotondo D (ed) Lipids in Immune Function and Inflammatory Dirorders. University of Sussex, Sussex, UK, pp 277-281
5. Khalfoun B, Thibault G, Lacord M, Gruel Y, Bardos P, Lebranchu Y 1996 Docosahexaenoic and eicosapentaenoic acids inhibit human lymphoproliferative responses in vitro but not the expression of T cell surface activation markers. Scand J Immunol 43:248-256
6. Hansen AE 1937 Reduced plasma essential fatty acid levels in patients with eczema. Am J Dis Child 53:933-946
7. Manku MS, Horrobin DF, Morse NL, Wright S, Burton JL 1984 Essential fatty acids in the plasma phospholipids of patients with atopic eczema. Br J Dermatol 110:643-648
8. Wright S 1985 Atopic dermatitis and essential fatty acids: a biochemical basis for atopy? Acta Derm Venereol 114(suppl):143-145
9. Oliwiecki S, Burton JL, Elles K, Horrobin DF 1990 Levels of essential and other fatty acids in plasma and red cell phospholipids from normal controls and patients with atopic eczema. Acta Derm Venereol 71:224-228
10. Lindskov R, Hølmer G 1992 Polyunsaturated fatty acids in plasma, red blood cells and mononuclear cell phospholipids of patients with atopic dermatitis. Allergy 47:517-521
11. Yu G, Björkstén B 1998 Serum levels of phospholipid fatty acids in mothers and their babies in relation to allergic disease. Eur J Pediatr 157:298-303
12. Strannegård IL, Svennerholm M, Strannegård Ö 1987 Essential fatty acids in serum lecithin of children with atopic dermatitis and in umbilical cord serum of infants with high or low IgE levels. Int Arch Allergy Appl Immunol 82:422-423
13. Yu G, Kjellman N-IM, Björkstén B 1996 Phospholipid fatty acids in cord blood: family history and development of allergy. Acta Paediatr 85:679-683
14. Melnik B, Plewig G, Tschung T 1991 Are deficiencies of prostaglandin-E-mediated immunoregulation involved in increased IgE synthesis of atopic mononuclear cells in vitro? Allergy 46:502-506
15. Rockling RE, Thistle L, Gallant L, Manku MS, Horrobin D 1986 Altered LA content in polymorphonuclear leukocytes and mononuclear cells from patients with allergic rhinitis and/or asthma. Lipids 21:17-20
16. Manku MS, Horrobin DF, Morse NL, Wright S, Burton JL 1984 Abnormalities in essential fatty acid metabolism in patients with atopic eczema. Br J Dermatol 110:643-648
17. Melnik B, Plewig G 1992 Are disturbances of ω-6-fatty acid metabolism involved in the pathogenesis of atopic dermatitis? Acta Derm Venereol 176(suppl):77-85
18. Morse PF, Horrobin DF, Manku MS, Steward JCM, Allen R, Littlewood S, Wright S, Burton J, Gould DJ, Holt PJ Jansen CT, Mattila L, Meigel W, Dettke TH, Wexler D, Guenther L, Bordoni A, Patrizzi A 1989 Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. Br J Dermatol 121:75-90
19. Wright S 1991 Essential fatty acids and atopic dermatitis. Pediatr Allergy Immunol 2(suppl 1):23-30
20. Berth-Jones J, Graham-Brown RAC 1993 Placebo controlled trial of essential fatty acid supplementation in atopic dermatitis. Lancet 341:1557-1560
21. Koletzko B, Thiel I, Obiodun P 1992 The fatty acid composition of human milk in Europe and Africa. J Pediatr 120:S62-S70
22. Wright S, Bolton C 1989 Breast milk fatty acids in mothers of children with atopic eczema. Br J Nutr 62:693-697
23. Schroten H, Schöls K, Melnik B, von Kries R, Wahn V, Biggemann B 1992 Breast milk of atopic mothers provides their infants with normal amounts of ω-6-fatty acids. Pediatr Allergy Immunol 3:140-143
24. Businco L, Ioppi M, Morse NL, Nisini R, Wright S 1993 Breast milk from mothers of children with newly developed atopic eczema has low levels of long chain polyunsaturated fatty acids. J Allergy Clin Immunol 91:1134-1139
25. Koletzko B, Mrotzek M, Bremer HJ 1988 The fatty acid composition of mature human milk in Germany. Am J Clin Nutr 47:954-959
26. Yu G, Duchén K, Björkstén B Fatty acid composition in colostrum and mature breast milk during the first 6 months of lactation from allergic and non-allergic mothers. Acta Paediatr (in press)
27. Hattevig G, Kjellman B, Björkstén B 1993 Appearance of IgE antibodies to ingested and inhaled allergens during the first 12 years of life in atopic and non-atopic children. Pediatr Allergy Immunol 4:182-186
28. Magnusson KF 1989 Breast milk antibodies to foods in relation to maternal diet, maternal atopy and the development of atopic disease in the baby. Int Arch Allergy Appl Immunol 90:297-300
29. Innis SM 1992 Plasma and red blood cell fatty acid values as indexes of essential fatty acids in the developing organs of infants fed with milk or formulas. J Pediatr 120:s78-S86
30. Decsi T, Koletzko B 1995 Growth, fatty acid composition of plasma lipid classes, and plasma retinol and α-tocopherol concentrations in full term infants fed formula enriched with ω-6 and ω-3 long chain polyunsaturated fatty acids. Acta Pediatr 84:725-732
31. Björkstén B 1983 Does breast feeding prevent the development of allergy? Immunol Today 4:215-217
32. Saarinen UM, Kajosaari M 1995 Breast feeding as prophylaxis against atopic disease: prospective follow up study until 17 years old. Lancet 346:1065-1069
33. Hanson LA, Ahlstedt S, Andersson B, Carlsson B, Fällström SP, Mellander L, Porras O, Söderström T, Svanborg Eden C,1985 Protective factors in milk and the development of the immune system. Pediatrics 75(suppl):172-176
34. Machtinger S, Moss R 1986 Cow's milk allergy in breast feed infants: the role of allergen and maternal secretory IgA antibody. J Allergy Clin Immunol 77:341-347
35. Wu D, Meydani SN, Meydani M, Hayek MG, Huth P, Nicolosi RJ 1996 Immunologic effects of marine- and plant-derived n-3 polyunsaturated fatty acids in nonhuman primates. Am J Clin Nutr 63:273-280
36. Gold KN, Weyand CM, Goronzy JJ 1994 Modulation of helper T cell function by prostaglandins. Arthritis Rheum 37:925-933
37. + T cells inhibits acquisition of ability to produce IFN-γ and IL-2 but not IL-4 and IL-5. J Immunol 155:4604-4612
38. Palkowetz KH RC, Garofalo L, Rudloff HE, Schmalstieg FC, Goldman AS 1994 Production of interleukin-6 and interleukin-8 by human mammary gland epithelial cells. J Reprod Immunol 126:57-64
39. Bertotto A, Gerli R, Fabietti G, Crupi S, Arcangeli C, Scalise F, Vaccaro R 1990 Human breast milk T lymphocytes display the phenotype and functional characteristics of memory T cells. Eur J Immunol 20:1877-1880
40. Skansén-Saphir U, Lindfors A, Andersson U 1993 Cytokine production in mononuclear cells of human milk studied at the single-cell level. Pediatr Res 34:213-216