ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 10, 2009, Pages 1678-1683

  Bacci, Simonetta ^a   Di Paola, Rosa ^a   Menzaghi, Claudia ^a   Di Fulvio, Patrizia ^b   Di Silvestre, Sara ^b   Pellegrini, Fabio ^c   Baratta, Roberto ^d   Marucci, Antonella ^a   Mastroianno, Sandra ^a   Fini, Grazia ^a   Formoso, Gloria ^b   Consoli, Agostino ^b   Perticone, Francesco ^a,e   Frittitta, Lucia ^d   Pandolfi, Assunta ^b   Trischitta, Vincenzo ^a,f  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c Consorzio Mario Negri Sud ^*  (Italy)

^d UNIVERSITY OF CATANIA   (Italy)

^e UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^f SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Arterial stiffness; Cardiovascular disease; Endothelial dysfunction; ENPP 1 gene; Insulin resistance

Indexed keywords

GLYCOPROTEIN; INSULIN; INSULIN RECEPTOR; NITRIC OXIDE SYNTHASE; PLASMA CELL ANTIGEN 1; PROTEIN KINASE B; UNCLASSIFIED DRUG; ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1; INORGANIC PYROPHOSPHATASE; PHOSPHODIESTERASE;

ADULT; ARTICLE; AUTOPHOSPHORYLATION; CARDIOVASCULAR RISK; CAUCASIAN; CONTROLLED STUDY; DIABETOGENESIS; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HERITABILITY; HETEROZYGOTE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULSE PRESSURE; SIGNAL TRANSDUCTION; BLOOD PRESSURE; CELL CULTURE; ENZYMOLOGY; GENETICS; HYPERTENSION; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; PHYSIOLOGY; SYSTOLE;

ADULT; BLOOD PRESSURE; CELLS, CULTURED; ENDOTHELIAL CELLS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; HYPERTENSION; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORYLATION; POLYMORPHISM, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; PYROPHOSPHATASES; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; SYSTOLE;

EID: 70349574150     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.189191     Document Type: Article

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